BR112021026859A2 - Usos terapêuticos de soluções oxidantes ácidas hipotônicas - Google Patents

Usos terapêuticos de soluções oxidantes ácidas hipotônicas

Info

Publication number
BR112021026859A2
BR112021026859A2 BR112021026859A BR112021026859A BR112021026859A2 BR 112021026859 A2 BR112021026859 A2 BR 112021026859A2 BR 112021026859 A BR112021026859 A BR 112021026859A BR 112021026859 A BR112021026859 A BR 112021026859A BR 112021026859 A2 BR112021026859 A2 BR 112021026859A2
Authority
BR
Brazil
Prior art keywords
therapeutic uses
acid oxidizing
hypotonic
oxidizing solutions
caused
Prior art date
Application number
BR112021026859A
Other languages
English (en)
Inventor
Giorgio Reiner
Paolo Galfetti
De Noni Roberto
Original Assignee
Applied Pharma Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Pharma Res filed Critical Applied Pharma Res
Publication of BR112021026859A2 publication Critical patent/BR112021026859A2/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/20—Elemental chlorine; Inorganic compounds releasing chlorine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

usos terapêuticos de soluções oxidantes ácidas hipotônicas. a invenção se refere aos métodos para tratar ou prevenir úlceras causadas por epidermólise bolhosa ("eb"), toxicidades da pele induzidas pelo inibidor de egfr, lesões causadas pela doença de hailey-hailey ("hhd"), úlceras de buruli e infecções causadas por sars-cov-2, aplicando topicamente uma solução ácida oxidante hipotônica contendo ácido hipocloroso (hclo) na área afetada.
BR112021026859A 2019-07-03 2020-07-02 Usos terapêuticos de soluções oxidantes ácidas hipotônicas BR112021026859A2 (pt)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201962870100P 2019-07-03 2019-07-03
US201962870096P 2019-07-03 2019-07-03
US201962935283P 2019-11-14 2019-11-14
US201962937885P 2019-11-20 2019-11-20
US201962937884P 2019-11-20 2019-11-20
PCT/IB2020/056277 WO2021001789A1 (en) 2019-07-03 2020-07-02 Therapeutic uses of oxidising hypotonic acid solutions

Publications (1)

Publication Number Publication Date
BR112021026859A2 true BR112021026859A2 (pt) 2022-02-22

Family

ID=71527866

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021026859A BR112021026859A2 (pt) 2019-07-03 2020-07-02 Usos terapêuticos de soluções oxidantes ácidas hipotônicas

Country Status (11)

Country Link
US (1) US20220241324A1 (pt)
EP (1) EP3993811A1 (pt)
JP (1) JP2022538900A (pt)
KR (1) KR20220034142A (pt)
CN (1) CN114080230A (pt)
AU (1) AU2020298870A1 (pt)
BR (1) BR112021026859A2 (pt)
CA (1) CA3145974A1 (pt)
CO (1) CO2021018273A2 (pt)
IL (1) IL289496A (pt)
WO (1) WO2021001789A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230149444A1 (en) * 2020-04-03 2023-05-18 Phase One Health, Llc Hypochlorous acid solutions and methods of use
US11826382B2 (en) 2020-05-01 2023-11-28 Tygrus, LLC Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
US11642372B2 (en) 2020-05-01 2023-05-09 Tygrus, LLC Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
WO2022119661A1 (en) * 2020-12-04 2022-06-09 Tygrus, LLC THERAPEUTIC MATERIAL WITH LOW pH AND LOW TOXICITY ACTIVE AGAINST AT LEAST ONE PATHOGEN FOR ADDRESSING PATIENTS WITH RESPIRATORY ILLNESSES
US20230149448A1 (en) * 2021-06-03 2023-05-18 Briotech, Inc. Methods for preventing and treating respiratory infections via modification of virus receptor binding domains using hypohalous acids

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000226680A (ja) * 1998-12-02 2000-08-15 Asahi Pretec Corp 殺菌性を有する電解水の製造方法及び装置
NZ598070A (en) 2005-10-28 2013-03-28 Akuatech S R L New highly stable aqueous solution, electrode with nanocoating for preparing the solution and method for making this electrode
PL2162140T3 (pl) * 2007-04-25 2013-10-31 Apr Nanotechnologies S A Wysoce stabilna woda elektrolityczna ze zmniejszoną szerokością połówkową linii widmowej NMR
AU2015364697A1 (en) * 2014-12-16 2017-07-13 Realm Therapeutics, Inc. Hypochlorous acid formulations and methods for treating skin conditions
CN106943429A (zh) * 2016-06-28 2017-07-14 黄坚文 一种次氯酸溶液的制作方法及其医学临床应用

Also Published As

Publication number Publication date
WO2021001789A1 (en) 2021-01-07
KR20220034142A (ko) 2022-03-17
JP2022538900A (ja) 2022-09-06
EP3993811A1 (en) 2022-05-11
CO2021018273A2 (es) 2022-01-17
AU2020298870A1 (en) 2022-02-24
IL289496A (en) 2022-02-01
US20220241324A1 (en) 2022-08-04
CN114080230A (zh) 2022-02-22
CA3145974A1 (en) 2021-01-07

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