BR112019015139B1 - Fused HETEROCYCLIC COMPOUND, COMPOSITION FOR CONTROL OF A HARMFUL ARTHROPOD COMPRISING THE SAME AND NON-THERAPEUTIC METHOD FOR CONTROL OF A HARMFUL ARTHROPOD - Google Patents

Abstract

The present invention relates to a heterocyclic compound which has an excellent control effect against harmful arthropods and which is represented by formula (I) (in the formula, Q means a group represented by Q1 or the like, A2 means a nitrogen atom or CR4a, A3 means a nitrogen atom or CR4b, A4 means a nitrogen atom or CR4c, and T means a linear C1-C10 hydrocarbon group having one or more halogen atoms, or the like); and a composition containing this compound and one or more components selected from the group consisting of group (a), group (b), group (c), group (d) and group (e) listed in the description.

Description

TECHNICAL FIELD

[001] This application claims the priority and benefit of Japanese Patent Application No. 2017-010118 filed on January 24, 2017, the entire contents of which are incorporated herein by reference.

[002] The present invention relates to a heterocyclic compound and a composition for controlling harmful arthropods comprising the same.

PREVIOUS TECHNIQUE

[003] To date, in order to control harmful arthropods, several compounds have been studied and are involved in practical use.

[004] Likewise, it is known that a certain class of compounds has an effect on pest control (see Patent Document 1).

QUOTE LIST PATENT DOCUMENT

[005] Patent Document 1: WO 2016/121969 A1

SUMMARY OF THE INVENTION (PROBLEMS TO BE SOLVED BY THE INVENTION)

[006] An object of the present invention is to provide a compound having excellent efficacy for controlling harmful arthropods.

(MEANS TO SOLVE PROBLEMS)

[007] In other words, the present invention is as follows.

[008] [1] A compound represented by formula (I):

[009] [in which

[0010] Q represents a group represented by the following formula Q1, a group represented by the following formula Q2, a group represented by the following formula Q3, or a group represented by the following formula Q4:

[0011] (where

[0012] n is 0, 1 or 2,

[0013] R2 represents a cyclopropyl group, a cyclopropyl-methyl group, or a C1-C6 alkyl group optionally having one or more halogen atoms,

[0014] Z1 represents a nitrogen atom or CR3c,

[0015] Z2 represents a nitrogen atom or CR3d,

[0016] Z3 represents a nitrogen atom or CR3e,

[0017] Z4 represents NR34, CR36R37or C(O),

[0018] Z5 represents NR35, CR38R39or C(O),

[0019] R3a, R3b, R3c, R3d and R3e each independently represents a C1-C6 chain hydrocarbon group optionally having one or more substituents selected from Group B, a C3-C7 cycloalkyl group optionally having one or more substituents selected from Group E, a phenyl group optionally having one or more substituents selected from Group H, a five- or six-membered aromatic heterocyclic group optionally having one or more substituents selected from Group H, OR12, NR11R12, NR11aR12a, NR29NR11R12, NR29OR11, NR11C(O) R13, NR29NR11C(O)R13, NR11C(O)OR14, NR29NR11C(O)OR14, NR11C(O)NR15R16, NR29NR11C(O)NR15R16, N=CHNR15R16, N=S(O)xR15R16, C(O)OR17, a cyano group, a nitro group, a halogen atom or a hydrogen atom,

[0020] x is 0 or 1,

[0021] R34 and R35 each independently represent a C1-C6 chain hydrocarbon group optionally having one or more substituents selected from Group B, a phenyl group optionally having one or more substituents selected from Group C, an aromatic heterocyclic group of five or six members optionally having one or more substituents selected from Group C, a C3-C7 aliphatic hydrocarbon group optionally having one or more substituents selected from Group C, C(O)ORd, C(O)Rd, C(O)NReRf, S(O)2Ri, or a hydrogen atom,

[0022] R36, R37, R38 and R39 each independently represent a C1-C6 chain hydrocarbon group optionally having one or more substituents selected from Group B, a phenyl group optionally having one or more substituents selected from Group C, a hydrocarbon group aliphatic C3-C7 optionally having one or more substituents selected from Group C, or a hydrogen atom,

[0023] Rd represents a C1 C6 chain hydrocarbon group optionally having one or more halogen atoms, or a hydrogen atom,

[0024] Ree Rfeach independently represents a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, a C3-C7 aliphatic hydrocarbon group optionally having one or more halogen atoms, or a hydrogen atom,

[0025] Ri represents a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms),

[0026] A2 represents a nitrogen atom or CR4a,

[0027] A3 represents a nitrogen atom or CR4b,

[0028] A4 represents a nitrogen atom or CR4c,

[0029] R4a, R4b and R4c each independently represent a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, a nitro group, OR18, NR18R19, a cyano group, a halogen atom or a hydrogen atom,

[0030] R18 represents a C1 C6 chain hydrocarbon group optionally having one or more halogen atoms,

[0031] R19 represents a C1C6 chain hydrocarbon group optionally having one or more halogen atoms or a hydrogen atom,

[0032] T represents a C1C10 chain hydrocarbon group having one or more halogen atoms, a (C1-C5 alkoxy) C2-C5 alkyl group having one or more halogen atoms, a (C1C5 alkylsulfanyl) C2-C5 alkyl group having one or more halogen atoms, a (C1-C5 alkylsulfinyl) C2-C5 alkyl group having one or more halogen atoms, a (C1-C5 alkylsulfonyl) C2-C5 alkyl group having one or more halogen atoms, a (C3-C7 cycloalkyl) C1-C3 alkyl group having one or more substituents selected from Group G, a C3-C7 cycloalkyl group having one or more substituents selected from Group G, OR1, S(O)mR1, OS(O) 2R1, CH2OR1, NR1R24, C(O)R1, C(O)NR1R24, NR24C(O)R1, N=CR1R30, a group represented by the following formula T-1, a group represented by the following formula T-2, a group represented by the following formula T-3, a group represented by the following formula T-4, a group represented by the following formula T-5, a group represented by the following formula T-6, a group represented by the following formula T-7, a group represented by the following formula T-8, a group represented by the following formula T-9, a group represented by the following formula T-10, a group represented by the following formula T-11, or a group represented by the following formula T-12:

[0033] X1 represents a nitrogen atom, or CR1a,

[0034] X2 represents a nitrogen atom, or CR1b,

[0035] X3 represents a nitrogen atom, or CR1c,

[0036] X4 represents a nitrogen atom, or CR1d,

[0037] X5 represents a nitrogen atom, or CR1e,

[0038] R1a, R1b, R1c, R1de R1e each independently represents a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, a C3-C6 cycloalkyl group optionally having one or more halogen atoms, a of halogen or a hydrogen atom,

[0039] Y1 represents NR25, an oxygen atom or a sulfur atom,

[0040] Y2 represents a nitrogen atom, or CR26,

[0041] Y3 represents a nitrogen atom, or CR27,

[0042] Y4 represents a nitrogen atom, or CR28,

[0043] R25 represents a C1C6 chain hydrocarbon group optionally having one or more halogen atoms, a C1-C6 alkoxy group optionally having one or more halogen atoms, a C3-C7 cycloalkyl group optionally having one or more halogen atoms, or a (C3-C7 cycloalkyl) C1-C6 alkyl group optionally having one or more halogen atoms,

[0044] R26, R27 and R28 each independently represent a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, a C3-C6 cycloalkyl group optionally having one or more halogen atoms, a halogen atom or a of hydrogen,

[0045] R1x represents OR7, OS(O)2R7, S(O)mR7, NR8S(O)2R7, a C1-C5 chain hydrocarbon group having one or more halogen atoms, a cyano group or a halogen atom,

[0046] R1y represents OR7, OS(O)2R7, S(O)mR7, NR8S(O)2R7, a cyano group, a C1-C5 chain hydrocarbon group having one or more halogen atoms or one halogen atom,

[0047] R1ay and R7each independently represents a C1-C6 chain hydrocarbon group having one or more halogen atoms,

[0048] R8 represents a C1C6 chain hydrocarbon group having one or more halogen atoms, or a hydrogen atom,

[0049] m is 0, 1, or 2,

[0050] R1 represents a C1C10 chain hydrocarbon group having one or more halogen atoms, a (C1-C5 alkoxy) C2-C5 alkyl group having one or more halogen atoms, a (C1C5 alkylsulfanyl) C2-C5 alkyl group having one or more halogen atoms, a (C1-C5 alkylsulfinyl) C2-C5 alkyl group having one or more halogen atoms, a (C1-C5 alkylsulfonyl) C2-C5 alkyl group having one or more halogen atoms, a (C3-C7 cycloalkyl) C1-C3 alkyl group having one or more substituents selected from Group G or a C3-C7 cycloalkyl group having one or more substituents selected from Group G,

[0051] R11, R17, R24 and R29 each independently represent a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, or a hydrogen atom,

[0052] R30 represents a C1C6 chain hydrocarbon group optionally having one or more halogen atoms, or a hydrogen atom,

[0053] R12 represents a C1C6 chain hydrocarbon group optionally having one or more halogen atoms, a C1-C6 alkyl group having a substituent selected from Group F, a phenyl group optionally having one or more substituents selected from Group H, a group five- or six-membered aromatic heterocyclic optionally having one or more substituents selected from Group H, S(O)2R23, or a hydrogen atom,

[0054] R23 represents a C1C6 chain hydrocarbon group optionally having one or more halogen atoms, or a phenyl group optionally having one or more substituents selected from Group D,

[0055] R11a and R12a, and the nitrogen atom to which they are attached are taken together to form a three- to seven-membered non-aromatic heterocyclic group optionally having one or more substituents selected from Group E,

[0056] R13 represents a C1C6 chain hydrocarbon group optionally having one or more halogen atoms, a C3-C7 cycloalkyl group optionally having one or more halogen atoms, a (C3-C6 cycloalkyl) C1-C3 alkyl group optionally having one or more halogen atoms, a phenyl group optionally having one or more substituents selected from Group D, a five- or six-membered aromatic heterocyclic group optionally having one or more substituents selected from Group D or a hydrogen atom,

[0057] R14 represents a C1 C6 chain hydrocarbon group optionally having one or more halogen atoms, a C3-C7 cycloalkyl group optionally having one or more halogen atoms, a (C3-C6 cycloalkyl) C1-C3 alkyl group optionally having one or more halogen atoms, or a phenyl C1-C3 alkyl group {the phenyl moiety in the phenyl C1-C3 alkyl group may optionally have one or more substituents selected from Group D},

[0058] R15 and R16 each independently represent a C1-C6 alkyl group optionally having one or more halogen atoms,

[0059] Group B: a group consisting of a C1-C6 alkoxy group optionally having one or more halogen atoms, a C3C6 alkenyloxy group optionally having one or more halogen atoms, a C3-C6 alkynyloxy group optionally having one or more halogen atoms, a C1-C6 alkylsulfanyl group optionally having one or more halogen atoms, a C1-C6 alkylsulfinyl group optionally having one or more halogen atoms, a C1-C6 alkylsulfonyl group optionally having one or more halogen atoms, a C3-C6 cycloalkyl group optionally having one or more halogen atoms, a cyano group, a hydroxy group and a halogen atom;

[0060] Group C: a group consisting of a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, a C1-C6 alkoxy group optionally having one or more halogen atoms, a C3- C6 alkenyloxy optionally having one or more halogen atoms, a C3-C6 alkynyloxy group optionally having one or more halogen atoms and a halogen atom;

[0061] Group D: a group consisting of a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, a hydroxy group, a C1-C6 alkoxy group optionally having one or more halogen atoms, a C3-C6 alkenyloxy group optionally having one or more halogen atoms, a C3C6 alkynyloxy group optionally having one or more halogen atoms, a sulfanil group, a C1-C6 alkylsulfanyl group optionally having one or more halogen atoms, a C1 group -C6 alkylsulfinyl optionally having one or more halogen atoms, a C1C6 alkylsulfonyl group optionally having one or more halogen atoms, an amino group, NHR21, NR21R22, C(O)R21, OC(O)R21, C(O )OR21, a cyano group, a nitro group and a halogen atom {R21 and R22 each independently represent a C1-C6 alkyl group optionally having one or more halogen atoms};

[0062] Group E: a group consisting of a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, a C1-C6 alkoxy group optionally having one or more halogen atoms, a C3- C6 alkenyloxy optionally having one or more halogen atoms, a C3-C6 alkynyloxy group optionally having one or more halogen atoms, a halogen atom, an oxo group, a hydroxy group, a cyano group and a nitro group;

[0063] Group F: a group consisting of a C1-C6 alkoxy group optionally having one or more halogen atoms, a phenyl group optionally having one or more substituents selected from Group D, an aromatic heterocyclic group of five or six members optionally having one or more substituents selected from Group D, a C3-C7 cycloalkyl group optionally having one or more halogen atoms, a three- to seven-membered non-aromatic heterocyclic group optionally having one or more substituents selected from Group C, an amino group, NHR21, NR21R22, and a cyano group;

[0064] Group G: a group consisting of a C1-C6 alkyl group having one or more halogen atoms;

[0065] Group H: a group consisting of a C1-C6 alkyl group optionally having one or more halogen atoms, OR10, NR9R10, C(O)R10, C(O)NR9R10, OC(O)R9, OC( O)OR9, NR10C(O)R9, NR10C(O)OR9, C(O)OR10, a halogen atom, a nitro group, a cyano group, an amino group, and a five- or six-membered aromatic heterocyclic group { R9 represents a C1-C6 alkyl group optionally having one or more halogen atoms, or a C3-C6 cycloalkyl group optionally having one or more halogen atoms, and R10 represents a C1-C6 alkyl group optionally having one or more halogen atoms, a C3-C6 cycloalkyl optionally having one or more halogen atoms, or a hydrogen atom}] (hereinafter, a compound represented by formula (I) is referred to as "Present compound" or "Compound of the present invention").

[0066] [2] The compound described in [1] wherein R4a, R4b and R4c each independently represents a hydrogen atom or a halogen atom, T represents OR1, R1 represents a C1-C5 chain hydrocarbon group having one or more halogen atoms, R2 represents a C1-C6 alkyl group, Q represents a group represented by the above formula Q1 or a group represented by the above formula Q2, R3a and R3beach independently represent a C1-C6 alkyl group optionally having one or more atoms of halogen, a phenyl group, a pyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenyl group, the pyridyl group, the pyrimidinyl group, the pyrazolyl group and the triazolyl group each independently may optionally have a or more substituents selected from Group H}, OR12, NR11R12, NR11C(O)R14, a halogen atom or a hydrogen atom, R3c, R3d and R3e each independently represents a C1-C6 alkyl group optionally having one or plus halogen atoms, OR12, a halogen atom or a hydrogen atom, Z4 represents CR36R37 or C(O), Z5 represents NR35 or CR38R39, R35 represents a C1-C6 alkyl group or a hydrogen atom, and R36 and R37 each independently represent a C1 group -C6 alkyl optionally having one or more halogen atoms, or a hydrogen atom, and R37 and R38 each represent a hydrogen atom.

[0067] [3] The compound described in [2] wherein R1 represents a C1-C5 alkyl group having three or more fluorine atoms, and R3a and R3b each independently represent a C1-C6 alkyl group optionally having one or more fluorine atoms. halogen, OR12, a halogen atom, or a hydrogen atom, and R4a, R4b and R4ceach represent a hydrogen atom.

[0068] [4] The compound described in [3] in which R2 represents an ethyl group, and R3c, R3d, R3e, R35, R36, R37, R38 and R39 each represent a hydrogen atom.

[0069] [5] The compound described in any one of [1] to [4] where A2 represents CR4a and A4 represents CR4c.

[0070] [6] The compound described in any one of [1] to [4] in which A2 represents CR4a, A3 represents CR4b and A4 represents CR4c.

[0071] [7] The compound described in [1] where A2 represents CR4a, A3 represents CR4b, A4 represents CR4c, R4a, R4b and R4c each independently represents a hydrogen atom or a halogen atom, T represents OR1, R1 represents a hydrocarbon group - grandson of C1-C5 chain having one or more halogen atoms, R2 represents a C1-C6 alkyl group, Q represents a group represented by the above formula Q1, R3a and R3b each independently represent a C1-C6 alkyl group optionally having one or plus halogen atoms, a phenyl group, a pyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenyl group, the pyridyl group, the pyrimidinyl group, the pyrazolyl group and the triazolyl group each independently can optionally having one or more substituents selected from Group H}, OR12, NR11R12, NR11C(O)OR14, a halogen atom or a hydrogen atom, and R3c, R3d and R3e each independently represents a C1C6 alkyl group optionally having one or more atoms of halogen, OR12, a halogen atom or a hydrogen atom.

[0072] [8] The compound described in [7] wherein R1 represents a C1-C5 alkyl group having three or more fluorine atoms, R3a and R3b each independently represent a C1-C6 alkyl group optionally having one or more halogen atoms, OR12, a halogen atom, or a hydrogen atom, and R4a, R4b and R4c each represent a hydrogen atom.

[0073] [9] The compound described in [7] or [8] in which R3c, R3d and R3e each represent a hydrogen atom.

[0074] [9-2] The compound described in [7] or [8] in which R2 represents an ethyl group, Z1 represents CR3c, Z2 represents a nitrogen atom or CR3d, Z3 represents a nitrogen atom, and R3c and R3d each represent a hydrogen atom.

[0075] [10] The compound described in [1] in which A2 represents CR4a, A3 represents CR4b, A4 represents CR4c, R4a, R4b and R4c each independently represents a hydrogen atom or a halogen atom, T represents OR1, R1 represents a hydrocar group - C1-C5 chain bone having one or more halogen atoms, R2 represents a C1-C6 alkyl group, Q represents a group represented by the above formula Q2, R3a and R3beach independently represents a C1-C6 alkyl group optionally having a or more halogen atoms, a phenyl group, a pyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenyl group, the pyridyl group, the pyrimidinyl group, the pyrazolyl group and the triazolyl group each independently may optionally have one or more substituents selected from Group H}, OR12, NR11R12, NR11C(O)OR14, a halogen atom or a hydrogen atom, Z4 represents CR36R37or C(O), Z5 represents NR35or CR38R39, R3e represents a C1- group C6 alkyl optionally having one or more halogen atoms, OR12, a halogen atom or a hydrogen atom, R35 represents a C1-C6 alkyl group or a hydrogen atom, R36 and R38 each independently represent a C1-C6 alkyl group optionally having a or more halogen atoms, or one hydrogen atom, and R37 and R38 each represent one hydrogen atom.

[0076] [11] The compound described in [10] wherein R1 represents a C1-C5 alkyl group having three or more fluorine atoms, R3a and R3b each independently represent a C1-C6 alkyl group optionally having one or more halogen atoms, OR12, a halogen atom, or a hydrogen atom, and R4a, R4b and R4c each represent a hydrogen atom.

[0077] [12] The compound described in [10] or [11] in which R2 represents an ethyl group, and R35, R36, R37, R38, and R39 each represent a hydrogen atom.

[0078] [12-2] The compound described in [10] or [13] in which R2represents an ethyl group, Z3represents a nitrogen atom, Z4represents CR36R37or C(O), Z5represents CR38R39, and R36, R37, R38and R39 each represents a hydrogen atom.

[0079] [13] A composition for controlling an arthropod in the cive comprising the compound described in any one of [1] to [12], [9-2] or [12-2] and an inert vehicle.

[0080] [14] A method for controlling a harmful arthropod comprising applying an effective amount of the compound according to any one of [1] to [12], [9-2] or [12-2] to a harmful arthropod or a habitat where a harmful arthropod lives.

[0081] [15] A composition comprising one or more ingredients selected from the group consisting of the following Group (a), Group (b), Group (c), Group (d) and Group (e), and the compound according to any of [1] to [12], [9-2] or [12-2],

[0082] Group (a): a group consisting of insecticidal ingredients, miticide ingredients and nematicide ingredients;

[0083] Group (b): fungicidal ingredients;

[0084] Group (c): plant growth modulating ingredients;

[0085] Group (d): phytotoxicity-reducing ingredients; It is

[0086] Group (e): synergistic ingredients

[0087] (hereinafter referred to as "Present composition" or "Composition of the present invention").

[EFFECT OF THE INVENTION]

[0088] The present invention can control harmful arthropods.

MODE OF CARRYING OUT THE INVENTION

[0089] The substituents as described here are explained.

[0090] The term "halogen atom" represents fluorine atom, chlorine atom, bromine atom or iodine atom.

[0091] When the substituent has two or more halogen atoms, these halogen atoms can be identical or different from each other.

[0092] The expression of "CX-CY" as used herein represents that the number of carbon atoms is from X to Y. For example, the expression of "C1-C6" represents that the number of carbon atoms is 1 to 6.

[0093] The term "chain hydrocarbon group" represents an alkyl group, an alkenyl group or an alkynyl group.

[0094] Examples of the term "alkyl group" include methyl group, ethyl group, propyl group, isopropyl group, 1,1-dimethylpropyl group, 1,2-dimethylpropyl group, 1-ethylpropyl group, butyl group, sec-butyl group , tert-butyl group, pentyl group, hexyl group, heptyl group, octyl group, nonyl group and decyl group.

[0095] Examples of the term "alkenyl group" include vinyl group, 1-propenyl group, 2-propenyl group, 1-methyl-1-propenyl group, 1-methyl-2-propenyl group, 1,2- dimethyl-1-propenyl, 1-ethyl-2-propenyl group, 3-butenyl group, 4-pentenyl group, 5-hexenyl group, 6-heptenyl group, 7-octenyl group, 8-nonenyl group and 9-decenyl group.

[0096] Examples of the term "alkynyl group" include ethynyl group, 1-propynyl group, 2-propynyl group, 1-methyl-2-propynyl group, 1,1-dimethyl-2-propynyl group, 1- ethyl-2-propynyl, 2-butynyl group, 4-pentynyl group, 5-hexinyl group, 6-heptynyl group, 7-octynyl group, 8-noninyl group and 9-decynyl group.

[0097] Examples of the term "C1-C6 alkyl group having one or more halogen atoms" include trifluoromethyl group, 2,2,2-trifluoroethyl group, 2-bromo-1,1,2,2-tetrafluoroethyl group, 2,2,3,3-tetrafluoropropyl, 1-methyl-2,2,3,3-tetrafluoropropyl group and perfluorohexyl group.

[0098] Examples of the term "C1-C5 alkyl group having three or more fluorine atoms" include trifluoromethyl group, 2,2,2-trifluoroethyl group, 2,2,3,3,3-pentafluoropropyl group, group 2, 2,3,3,4,4,4- heptafluoropropyl and perfluoropropyl group.

[0099] Examples of the term "C3-C7 aliphatic hydrocarbon group" include cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl and cycloethyl.

[00100] Examples of the term "cycloalkyl group" include cyclopropyl group, cyclobutyl group, cyclopentyl group, cyclohexyl group and cycloheptyl group.

[00101] Examples of the term "C3-C7 cycloalkyl group optionally having one or more halogen atoms" include 2,2-difluorocyclopropyl group, 1-(2,2,2-trifluoroethyl)cylopropyl group and 4-(trifluoromethyl) group cyclohexyl.

[00102] Examples of the term "alkoxy group" include methoxy group, ethoxy group, propoxy group, butoxy group, pentoxy group and hexyloxy group.

[00103] The term "C1-C6 alkoxy group optionally having one or more halogen atoms" represents a C1-C6 alkoxy group in which one or more hydrogen atoms are replaced with a halogen atom, and includes, for example, trifluoromethoxy group, difluoromethoxy group, 2,2,2-trichloroethoxy group and 2,2,2-trifluoroethoxy group.

[00104] The term "alkylsulfanyl group", "alkylsulfinyl group" and "alkylsulfonyl group" represents an alkyl group including an S(O)z moiety, respectively.

[00105] For example, examples of the "alkylsulfanyl group" when z is 0 include methylsulfanyl group, ethylsulfanyl group, propylsulfanyl group and isopropylsulfanyl group.

[00106] For example, examples of the "alkylsulfinyl group" when z is 1 include methylsulfinyl group, ethylsulfinyl group, propylsulfinyl group and isopropylsulfinyl group.

[00107] For example, examples of the "alkylsulfonyl group" when z is 2 include methylsulfonyl group, ethylsulfonyl group, propylsulfonyl group and isopropylsulfonyl group.

[00108] Examples of the term "three (3) to seven (7) membered non-aromatic heterocyclic group" include aziridine ring, azetidine ring, pyrrolidine ring, imidazoline ring, imidazolidine ring, piperidine ring , tetrahydropyrimidine ring, hexahydropyrimidine ring, piperazine ring, azepane ring, oxazolidine ring, isoxazolidine ring, 1,3-oxazinane ring, morpholine ring, 1,4-oxazepane ring, thiazolidine ring , isothiazolidine ring, 1,3-thiazinane ring, thiomorpholine ring and 1,4-thiazepane ring. Examples of the three- to seven-membered non-aromatic heterocyclic group optionally having one or more substituents selected from Group E include the following:

[00109] The term "(C1-C5 alkoxy) C2-C5 alkyl group having one or more halogen atoms" represents a group in which the (C1-C5 alkoxy) and/or the (C2-C5 alkyl) have a or more halogen atoms, and include, for example, the 2-(trifluoromethoxy)ethyl group, the 2,2-difluoro-3-methoxypropyl group, the 2,2-difluoro-3-(2,2, 2-trifluoroethoxy)propyl and the 3-(2-chloroethoxy)propyl group.

[00110] The term "(C1-C5 alkylsulfanyl) C2-C5 alkyl group having one or more halogen atoms" represents a group in which the (C1-C5 alkylsulfanyl) and/or the (C2-C5 alkyl) have a or more halogen atoms, and include, for example, the 2,2-difluoro-2-(trifluoromethylthio)ethyl group.

[00111] The term "(C1-C5 alkylsulfinyl) C2-C5 alkyl group having one or more halogen atoms" represents a group in which the (C1C5 alkylsulfinyl) and/or the (C2-C5 alkyl) have one or more halogen atoms, and include, for example, the 2,2-difluoro-2-(trifluoromethansulfinyl)ethyl group.

[00112] The term "(C1-C5 alkylsulfonyl) C2-C5 alkyl group having one or more halogen atoms" represents a group in which the (C1-C5 alkylsulfonyl) and/or the (C2-C5 alkyl) have a or more halogen atoms, and include, for example, the 2,2-difluoro-2-(trifluoromethansulfonyl)ethyl group.

[00113] The term "(C3-C7 cycloalkyl) C1-C3 alkyl group optionally having one or more halogen atoms" represents a group in which the (C3-C7 cycloalkyl) and/or the (C1-C3 alkyl) have one or more halogen atoms, and include, for example, the (2,2-difluorocyclopropyl)methyl group, the 2-cyclopropyl-1,1,2,2-tetrafluoroethyl group and the 2-(2,2-difluorocyclopropyl) group )-1,1,2,2-tetrafluoroethyl.

[00114] Examples of the term "phenyl C1-C3 alkyl group {the phenyl moiety in the phenyl C1-C3 alkyl group may optionally have one or more substituents selected from Group D}" include the benzyl group, the 2-fluorobenzyl group, the 4-chlorobenzyl group, the 4-(trifluoromethyl)benzyl group and the 2-[4-(trifluoromethyl)phenyl]ethyl group.

[00115] The term "five (5) or six (6) membered aromatic heterocyclic group" represents a five-membered aromatic heterocyclic group or a six-membered aromatic heterocyclic group, and examples of the five-membered aromatic heterocyclic group include the pyrrolyl group, furyl group, thienyl group, pyrazolyl group, imidazolyl group, triazolyl group, tetrazolyl group, oxazolyl group, isoxazolyl group, thiazolyl group, isothiazolyl group, oxadiazolyl group and thiadiazolyl group. As the five-membered aromatic heterocyclic group, the pyrrolyl group, pyrazolyl group, imidazolyl group, 1,2,4-triazolyl group, 1,2,3-triazolyl group or tetrazolyl group is preferably included. Examples of the six-membered aromatic heterocyclic group include the pyridyl group, pyridazinyl group, pyrimidinyl group and pyrazinyl group.

[00116] The term "five (5) or six (6) membered aromatic heterocyclic group" represents a five-membered aromatic heterocyclic group or a six-membered aromatic heterocyclic group.

[00117] Examples of the compound embodiment of the present invention include the following compounds.

[00118] [Modality 1] A compound of the present invention in which R3b represents a phenyl group optionally having one or more substituents selected from Group H, any six-membered aromatic heterocyclic group selected from Group V (the aromatic heterocyclic group six-membered heterocyclic group may optionally have one or more substituents selected from Group H), or any five-membered aromatic heterocyclic group selected from Group W (the five-membered aromatic heterocyclic group may optionally have one or more substituents selected from Group H }: {in the formulas, R3x represents a C1-C6 alkyl group optionally having one or more halogen atoms}.

[00119] [Modality 2] The compound of the present invention in which R2 represents a C1-C6 alkyl group, R3a and R3b each independently represent a C1-C6 alkyl group optionally having one or more halogen atoms, a phenyl group, a pyridyl, a pyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenyl group, the pyridyl group, the pyrimidinyl group, the pyrazolyl group and the triazolyl group each independently may optionally have one or more substituents selected from Group H} , OR12, NR11R12, NR11C(O)OR14, or a halogen atom, or a hydrogen atom, Q represents a group represented by the formula Q1, or a group represented by the formula Q2, R3c, R3d and R3e each independently represents a C1 group -C6 alkyl optionally having one or more halogen atoms, OR12, a halogen atom or a hydrogen atom, Z4 represents CR36R37 or C(O), Z5 represents NR35 or CR38R39, and R4a, R4b and R4c each independently represents a hydrogen atom or a halogen atom.

[00120] [Modality 3] The compound described in Embodiment 2 in which R3a and R3b each independently represent a C1C6 alkyl group optionally having one or more halogen atoms, OR12, a halogen atom, or a hydrogen atom, R35 represents a C1 group -C6 alkyl or a hydrogen atom, R36 and R38 each independently represent a C1-C6 alkyl group optionally having one or more halogen atoms or a hydrogen atom, and R37 and R39 each represent a hydrogen atom.

[00121] [Mode 4] The compound described in Mode 3 in which R4a, R4b and R4c each represent a hydrogen atom.

[00122] [Mode 5] The compound described in Mode 3 in which R3c, R3d, R3e, R4a, R4b and R4c each represents a hydrogen atom.

[00123] [Mode 6] The compound described in Mode 3 in which R36, R4a, R4b and R4c each represent a hydrogen atom.

[00124] [Mode 7] The compound described in Mode 3 in which R35, R38, R4a, R4b and R4c each represent a hydrogen atom.

[00125] [Mode 8] The compound described in Mode 3 in which R3a, R3d, R3e, R35, R36, R38, R4a, R4b and R4c each represents a hydrogen atom.

[00126] [Mode 9] The compound described in Mode 8 in which R2 represents an ethyl group, and n is 2.

[00127] [Mode 10] The compound described in Mode 2 in which Q represents a group represented by the formula Q1.

[00128] [Modality 11] The compound described in Embodiment 10 in which R3a and R3beach independently represent a C1C6 alkyl group optionally having one or more halogen atoms, OR12, a halogen atom or a hydrogen atom.

[00129] [Mode 12] The compound described in Mode 11 in which R4a, R4b and R4c each represent a hydrogen atom.

[00130] [Mode 13] The compound described in Mode 13 in which R3c, R3d, R3e, R4a, R4b and R4c each represents a hydrogen atom.

[00131] [Mode 14] The compound described in Mode 13 in which R2 represents an ethyl group, and n is 2.

[00132] [Mode 15] The compound described in Mode 2 in which Q represents a group represented by the formula Q2.

[00133] [Modality 16] The compound described in Embodiment 15 in which R3a and R3b each independently represent a C1C6 alkyl group optionally having one or more halogen atoms, OR12, a halogen atom or a hydrogen atom, R35 represents a C1- group C6 alkyl or a hydrogen atom, R36 and R38 each independently represent a C1-C6 alkyl group optionally having one or more halogen atoms or a hydrogen atom, and R37 and R39 each represent a hydrogen atom.

[00134] [Mode 17] The compound described in Mode 16 in which R4a, R4b and R4c each represent a hydrogen atom.

[00135] [Mode 18] The compound described in Mode 16 in which R3e, R4a, R4b and R4c each represent a hydrogen atom.

[00136] [Mode 19] The compound described in Mode 16 in which R36, R4a, R4b and R4c each represent a hydrogen atom.

[00137] [Mode 20] The compound described in Mode 16 in which R35, R38, R4a, R4b and R4c each represent a hydrogen atom.

[00138] [Mode 21] The compound described in Mode 16 in which R35, R36, R38, R3e, R4a, R4b and R4c each represents a hydrogen atom.

[00139] [Mode 22] The compound described in Mode 16 in which R2 represents an ethyl group, and n is 2.

[00140] [Modality 23] The compound described in Modality 2 in which A2 represents CR4a, and A4 represents CR4c.

[00141] [Modality 24] The compound described in Embodiment 23 wherein R3a and R3beach independently represent a C1C6 alkyl group optionally having one or more halogen atoms, OR12, a halogen atom, or a hydrogen atom, R35 represents a C1 group -C6 alkyl or a hydrogen atom, R36 and R38 each independently represent a C1-C6 alkyl group optionally having one or more halogen atoms or a hydrogen atom, and R37 and R39 each represent a hydrogen atom.

[00142] [Mode 25] The compound described in Mode 24 in which R4a, R4b and R4c each represent a hydrogen atom.

[00143] [Mode 26] The compound described in Mode 24 in which R3c, R3d, R3e, R4a, R4b and R4c each represent a hydrogen atom.

[00144] [Mode 27] The compound described in Mode 24 in which R36, R4a, R4b and R4c each represent a hydrogen atom.

[00145] [Mode 28] The compound described in Mode 24 in which R35, R38, R4a, R4b and R4c each represent a hydrogen atom.

[00146] [Mode 29] The compound described in Mode 24 in which R3c, R3d, R3e, R35, R36, R38, R4a, R4b and R4c each represents a hydrogen atom.

[00147] [Mode 30] The compound described in Mode 29 in which R2 represents an ethyl group, and n is 2.

[00148] [Mode 31] The compound described in Mode 23 in which Q represents a group represented by the formula Q1.

[00149] [Modality 32] The compound described in Embodiment 31 in which R3a and R3b each independently represent a C1C6 alkyl group optionally having one or more halogen atoms, OR12, a halogen atom, or a hydrogen atom, R35 represents a C1 group -C6 alkyl or a hydrogen atom, R36 and R38 each independently represent a C1-C6 alkyl group optionally having one or more halogen atoms or a hydrogen atom, and R37 and R39 each represent a hydrogen atom.

[00150] [Mode 33] The compound described in Mode 32 in which R4a, R4b and R4c each represent a hydrogen atom.

[00151] [Mode 34] The compound described in Mode 32 in which R3c, R3d, R3e, R4a, R4b and R4c each represents a hydrogen atom.

[00152] [Mode 35] The compound described in Mode 34 in which R2 represents an ethyl group, and n is 2.

[00153] [Mode 36] The compound described in Mode 23 in which Q represents a group represented by the formula Q2.

[00154] [Modality 37] The compound described in Embodiment 36 wherein R3a and R3b each independently represent a C1-C6 alkyl group optionally having one or more halogen atoms, OR12, a halogen atom, or a hydrogen atom, R35 represents a C1-C6 alkyl group or a hydrogen atom, R36 and R38 each independently represent a C1-C6 alkyl group optionally having one or more halogen atoms or a hydrogen atom, and R37 and R39 each represent a hydrogen atom.

[00155] [Mode 38] The compound described in Mode 37 in which R4a, R4b and R4c each represent a hydrogen atom.

[00156] [Mode 39] The compound described in Mode 37 in which R3e, R4a, R4b and R4c each represent a hydrogen atom.

[00157] [Mode 40] The compound described in Mode 37 in which R36, R4a, R4b and R4c each represent a hydrogen atom.

[00158] [Mode 41] The compound described in Mode 37 in which R35, R38, R4a, R4b and R4c each represent a hydrogen atom.

[00159] [Mode 42] The compound described in Mode 37 in which R35, R36, R38, R3e, R4a, R4b and R4c each represents a hydrogen atom.

[00160] [Mode 43] The compound described in Mode 42 in which R2 represents an ethyl group, and n is 2.

[00161] [Modality 44] The compound described in Embodiment 2 in which A2 represents CR4a, A3 represents CR4b and A4 represents CR4c.

[00162] [Modality 44] The compound described in Embodiment 44 wherein R3a and R3beach independently represent a C1C6 alkyl group optionally having one or more halogen atoms, OR12, a halogen atom, or a hydrogen atom, R35 represents a C1 group -C6 alkyl or a hydrogen atom, R36 and R38 each independently represent a C1-C6 alkyl group optionally having one or more halogen atoms, or a hydrogen atom, and R37 and R39 each represent a hydrogen atom.

[00163] [Mode 46] The compound described in Mode 45 in which R4a, R4b, and R4c each represent a hydrogen atom.

[00164] [Mode 47] The compound described in Mode 45 in which R3c, R3d, R3e, R4a, R4b and R4c each represent a hydrogen atom.

[00165] [Mode 48] The compound described in Mode 45 in which R36, R4a, R4b and R4c each represent a hydrogen atom.

[00166] [Mode 49] The compound described in Mode 45 in which R35, R38, R4a, R4b and R4c each represent a hydrogen atom.

[00167] [Mode 50] The compound described in Mode 45 in which R3c, R3d, R3e, R35, R36, R38, R4a, R4b and R4c each represents a hydrogen atom.

[00168] [Mode 51] The compound described in Mode 45 in which R2 represents an ethyl group, and n is 2.

[00169] [Mode 52] The compound described in Mode 44 in which Q represents a group represented by the formula Q1.

[00170] [Modality 53] The compound described in Embodiment 52 wherein R3a and R3b each independently represent a C1C6 alkyl group optionally having one or more halogen atoms, OR12, a halogen atom, or a hydrogen atom, R35 represents a C1 group -C6 alkyl or a hydrogen atom, R36 and R38 each independently represent a C1-C6 alkyl group optionally having one or more halogen atoms or a hydrogen atom, and R37 and R39 each represent a hydrogen atom.

[00171] [Modality 54] The compound described in Embodiment 53 in which R4a, R4b and R4c each represent a hydrogen atom.

[00172] [Mode 55] The compound described in Mode 53 in which R3c, R3d, R3e, R4a, R4b and R4c each represent a hydrogen atom.

[00173] [Mode 56] The compound described in Mode 55 in which R2 represents an ethyl group, and n is 2.

[00174] [Mode 57] The compound described in Mode 44 in which Q represents a group represented by the formula Q2.

[00175] [Modality 58] The compound described in Embodiment 57 wherein R3a and R3b each independently represent a C1C6 alkyl group optionally having one or more halogen atoms, OR12, a halogen atom, or a hydrogen atom, R35 represents a C1 group -C6 alkyl or a hydrogen atom, R36 and R38 each independently represent a C1-C6 alkyl group optionally having one or more halogen atoms or a hydrogen atom, and R37 and R39 each represent a hydrogen atom.

[00176] [Mode 59] The compound described in Mode 58 in which R4a, R4b and R4c each represent a hydrogen atom.

[00177] [Mode 60] The compound described in Mode 58 in which R3e, R4a, R4b and R4c each represent a hydrogen atom.

[00178] [Mode 61] The compound described in Mode 58 in which R36, R4a, R4b and R4c each represent a hydrogen atom.

[00179] [Mode 62] The compound described in Mode 58 in which R35, R38, R4a, R4b and R4c each represent a hydrogen atom.

[00180] [Mode 63] The compound described in Mode 58 in which R35, R36, R38, R3e, R4a, R4b and R4c each represents a hydrogen atom.

[00181] [Mode 64] The compound described in Mode 63 in which R2 represents an ethyl group, and n is 2.

[00182] [Modality 65] The compound described in any of Modalities 1 to 64 in which T represents a C1-C10 chain hydrocarbon group optionally having one or more halogen atoms, a group (C1-C5 alkoxy ) C2-C5 alkyl having one or more halogen atoms, a (C1-C5 alkylsulfanyl) C2-C5 alkyl group having one or more halogen atoms, a (C1-C5 alkylsulfinyl) C2-C5 alkyl group having one or more atoms halogen, a (C1-C5 alkylsulfonyl) C2-C5 alkyl group having one or more halogen atoms, a (C3-C7 cycloalkyl) C1-C3 alkyl group having one or more substituents selected from Group G, a C3 group -C7 cycloalkyl having one or more substituents selected from Group G, OR1, S(O)mR1, OS(O)2R1, or NR1R24.

[00183] [Modality 66] The compound described in any of Modalities 1 to 64 in which T represents a C1-C10 chain hydrocarbon group optionally having one or more halogen atoms, a group (C1-C5 alkoxy ) C2-C5 alkyl having one or more halogen atoms, a (C1-C5 alkylsulfanyl) C2-C5 alkyl group having one or more halogen atoms, a (C1-C5 alkylsulfinyl) C2-C5 alkyl group having one or more atoms halogen, a (C1C5 alkylsulfonyl) C2-C5 alkyl group having one or more halogen atoms, a (C3-C7 cycloalkyl) C1-C3 alkyl group having one or more substituents selected from Group G, a C3-C7 group cycloalkyl having one or more substituents selected from Group G, OR1, S(O)mR1, OS(O)2R1, or NR1R24, and R1 represents a C1-C5 chain hydrocarbon group having one or more halogen atoms.

[00184] [Modality 67] The compound described in any of Modalities 1 to 64 in which T represents a C1-C10 chain hydrocarbon group optionally having one or more halogen atoms, a group (C1-C5 alkoxy ) C2-C5 alkyl having one or more halogen atoms, a (C1-C5 alkylsulfanyl) C2-C5 alkyl group having one or more halogen atoms, a (C1-C5 alkylsulfinyl) C2-C5 alkyl group having one or more atoms halogen, a (C1C5 alkylsulfonyl) C2-C5 alkyl group having one or more halogen atoms, a (C3-C7 cycloalkyl) C1-C3 alkyl group having one or more substituents selected from Group G, a C3-C7 group cycloalkyl having one or more substituents selected from Group G, OR1, S(O)mR1, OS(O)2R1, or NR1R24, and R1 represents a C1-C5 alkyl group having three or more fluorine atoms.

[00185] [Mode 68] The compound described in any of Embodiments 1 to 64 where T represents OR1.

[00186] [Modality 69] The compound described in any of Modalities 1 to 64 in which T represents OR1, and R1 represents a C1-C5 chain hydrocarbon group having one or more halogen atoms.

[00187] [Modality 70] The compound described in any one of Embodiments 1 to 64 in which T represents OR1 and R1 represents a C1-C5 alkyl group having three or more fluorine atoms.

[00188] Next, a process for preparing the compound of the present invention is explained.

Process 1

[00189] A compound of the present invention can be prepared by reacting a compound represented by the formula (M-1) (hereinafter referred to as Compound (M-1)) with a compound represented by the formula (M-2) ( hereinafter referred to as Compound (M2)) in the presence of a metal catalyst. [where Xa represents a chlorine atom, a bromine atom, or an iodine atom, and the other symbols are the same as defined above.]

[00190] The reaction is generally carried out in a solvent. Examples of the solvent to be used in the reaction include ethers such as dimethoxyethane, 1,4-dioxane, tetrahydrofuran (hereinafter referred to as THF), ethylene glycol dimethyl ether, and methyl tert-butyl ether (hereinafter referred to as MTBE) (hereinafter referred to as ethers); aromatic hydrocarbons such as toluene and xylene (hereinafter referred to as aromatic hydrocarbons); polar aprotic solvents such as N-methyl pyrrolidone (hereinafter referred to as NMP), dimethyl sulfoxide (hereinafter referred to as DMSO) (hereinafter referred to as polar aprotic solvents); water; and these solvents mixed.

[00191] Examples of the metal catalyst to be used in the reaction include palladium catalysts such as tetrakis(triphenylphosphine)palladium(0), [1,1'-bis(diphenylphosphine)ferrocene] palladium(II) dichloride, tris (dibenzylideneacetone)dipalladium(0) and palladium(II) acetate.

[00192] A ligand or base can be added to the reaction as necessary.

[00193] Examples of the ligand to be used in the reaction include triphenylphosphine, 2',4',6'-triisopropyl-1,1'-biphenyl, 2-dicyclohexylphosphine-2',6'-dimethoxybiphenyl, 1,2-bis(diphenylphosphine)ethane, 2,2'-bipyridine, 2-aminoethanol , 8-hydroquinoline and 1,10-phenanthroline.

[00194] Example of the base to be used in the reaction include organic bases such as triethylamine, diisopropylethylamine, pyridine and 4-(dimethylamino)pyridine (hereinafter referred to as organic bases), alkali metal carbonates such as sodium carbonate and sodium carbonate. potassium (hereinafter referred to as alkali metal carbonates), tri-potassium phosphate and potassium fluoride.

[00195] In the reaction, the compound (M-2) is generally used within a molar ratio range of 1 to 10, the metal catalyst is generally used within a molar ratio range of 0.01 to 0 .5, the ligand is generally used within a molar ratio range of 0.01 to 1, and the base is generally used within a molar ratio range of 0.1 to 5, as opposed to 1 mol of the compound (M-1).

[00196] The reaction temperature of the reaction is generally within a range of -20 to 200 °C. The reaction period of the reaction is generally within a range of 0.1 to 24 hours.

[00197] When the reaction is completed, water is added to the reaction mixtures, and the reaction mixtures are extracted with organic solvents, and the organic layers are prepared (such as drying and concentration) to obtain the compound of the present invention.

Process 2

[00198] A compound represented by the formula (I-Q1a) (hereinafter referred to as Compound (I-Q1a)) can be prepared by reacting a compound represented by the formula (M-3) (hereinafter referred to as Compound (M-3)) with chloroacetaldehyde. [wherein the symbols are the same as defined above.]

[00199] The reaction is generally carried out in a solvent.

[00200] Examples of solvents to be used in the reaction include ethers; polar aprotic solvents; halogenated hydrocarbons such as dichloromethane and chloroform (hereinafter referred to as halogenated hydrocarbons); nitriles such as acetonitrile (hereinafter referred to as nitriles); alcohols such as methanol and ethanol (hereinafter referred to as alcohols); water; and these solvents mixed.

[00201] An acid or a base can be added to the reaction, and examples of the acid include hydrogen chloride, p-toluenesulfonic acid and 10-camphorsulfonic acid. Examples of the base include alkali metal carbonates and organic bases.

[00202] In the reaction, the acid or base is generally used within a molar ratio range of 0.1 to 10, and chloroacetaldehyde is generally used within a molar ratio range of 1 to 10, as opposed to 1 mol of the compound (M-3).

[00203] The reaction temperature of the reaction is generally within a range of -20 to 150 °C. The reaction period of the reaction is generally within a range of 0.5 to 24 hours.

[00204] When the reaction is completed, water is added to the reaction mixtures, and the reaction mixtures are extracted with organic solvents, and the organic layers are prepared (such as drying and concentration) to obtain the compound (I-Q1a ).

Process 3

[00205] A compound represented by the formula (I-Q1b) (hereinafter referred to as Compound (I-Q1b)) can be prepared by reacting a compound represented by the formula (M-4) (hereinafter referred to as Compound (M-4)) with a compound represented by the formula (R-1) (hereinafter referred to as Compound (R-1)). [wherein R3ca represents a C1-C6 hydrocarbon group optionally having one or more substituents selected from Group B, a C3-C7 cycloalkyl group optionally having one or more substituents selected from Group E, a phenyl group optionally having one or plus substituents selected from Group H, a five- to six-membered aromatic heterocyclic group optionally having one or more substituents selected from Group H, or a hydrogen atom, and the other symbols are the same as defined above.]

[00206] The reaction is generally carried out in a solvent. Examples of solvents to be used in the reaction include ethers, polar saprotic solvents, halogenated hydrocarbons, nitriles, alcohols, water, and these mixed solvents.

[00207] An acid or a base can be added to the reaction, and examples of the acid include hydrogen chloride, p-toluenesulfonic acid and 10-camphorsulfonic acid. Examples of the base include alkali metal carbonates and organic bases.

[00208] In the reaction, the acid or base is generally used within a molar ratio of 0.1 to 10, and the compound (R-1) is generally used within a molar ratio range of 1 to 10, as opposed to to 1 mol of the compound (M-4).

[00209] The reaction temperature of the reaction is generally within a range of -20 to 150 °C. The reaction period of the reaction is generally within a range of 0.5 to 24 hours.

[00210] When the reaction is completed, water is added to the reaction mixtures, and the reaction mixtures are extracted with organic solvents, and the organic layers are prepared (such as drying and concentration) to obtain the compound (I-Q1b ).

[00211] The compound (R-1) is a commercially available compound, or can be prepared according to the known method.

Process 4

[00212] A compound represented by the formula (I-Q2a) (hereinafter referred to as Compound (I-Q2a)) can be prepared by reacting a compound represented by the formula (M-5) (hereinafter referred to as Compound (M-5)) with 2-chloroethylamine. [wherein the symbols are the same as defined above.]

[00213] The reaction is generally carried out in a solvent. Examples of the solvent to be used in the reaction include ethers, polar aprotic solvents, halogenated hydrocarbons, nitriles, alcohols, water, and these mixed solvents.

[00214] The base can be added to the reaction, and examples of the base include alkali metal carbonates, and alkali metal hydrides such as sodium hydride (hereinafter referred to as alkali metal hydrides) and organic bases.

[00215] In the reaction, the base is generally used within a molar ratio range of 1 to 10, and 2-chloroethylamine is generally used within a molar ratio range of 1 to 10, as opposed to 1 mol of the compound (M-5).

[00216] The reaction temperature of the reaction is generally within a range of -20 to 150 °C. The reaction period of the reaction is generally within a range of 0.5 to 24 hours.

[00217] When the reaction is completed, water is added to the reaction mixtures, and the reaction mixtures are extracted with organic solvents, and the organic layers are prepared (such as drying and concentration) to obtain the compound (I-Q2a ).

[00218] The compound (M-5) can be prepared, for example, according to the method described in WO 2016/121969.

Process 5

[00219] A compound represented by the formula (I-Q2b) (hereinafter referred to as Compound (I-Q2b)) can be prepared by reacting the compound (M-4) with 1,1'-carbonyldiimidazole. [wherein the symbols are the same as defined above.]

[00220] The reaction is generally carried out in a solvent. Examples of the solvent to be used in the reaction include ethers, polar aprotic solvents, halogenated hydrocarbons, nitriles, alcohols, and these mixed solvents.

[00221] In the reaction, 1,1'-carbonyldiimidazole is generally used within a range of molar ratios of 1 to 10 as opposed to 1 mol of the compound (M-4).

[00222] The reaction temperature of the reaction is generally within a range of -20 to 120 °C. The reaction period of the reaction is generally within a range of 0.1 to 12 hours.

[00223] When the reaction is completed, water is added to the reaction mixtures, and the reaction mixtures are extracted with organic solvents, and the organic layers are prepared (such as drying and concentration) to obtain the compound (I-Q2b ).

Reference Process 1

[00224] The compound (M-2) can be prepared by reacting a compound represented by the formula (M-7) with bis(pinacolato)diboron. [wherein the symbols are the same as defined above.]

[00225] The reaction can be carried out, for example, according to the method described in Example 127 of WO 2015/153720.

Reference Process 2

[00226] A compound represented by the formula (M-7b) (hereinafter referred to as Compound (M-7b)) or a compound represented by the formula (M-7c) (hereinafter referred to as Compound (M-7c)) can be prepared by oxidizing a compound represented by the formula (M-7a) (hereinafter referred to as Compound (M-7a)). [where Z6-Z7 represents a group represented by the formula Q-1, a group represented by the formula Q2-1, a group represented by the formula Q3-1, or a group represented by the formula Q4-1, and the other symbols are the same as defined above.] [wherein the symbols are the same as defined above.]

[00227] These reactions can be carried out according to the method described in process 1 of WO 2013/018928.

Reference Process 3

[00228] Compound (M-7a) can be prepared by reacting a compound represented by the formula (M-8) (hereinafter referred to as Compound (M-8)) with a compound represented by the formula (R-2 ) (hereinafter referred to as Compound (R-2)) in the presence of a base. [wherein the symbols are the same as defined above.]

[00229] The reaction can be carried out according to the method described in process 5 of WO 2013/018928.

[00230] The compound (R-2) is a commercially available compound, or can be prepared according to the known method.

Reference Process 4

[00231] A compound represented by the formula (M-8-Q1a) (hereinafter referred to as Compound (M-8-Q1a)) can be prepared by reacting a compound represented by the formula (M-9 (hereinafter referred to as referred to as Compound (M-9)) with sodium azide. [where Xb represents a fluorine atom or a chlorine atom, and the other symbols are the same as defined above.]

[00232] The reaction can be conducted according to the method described in Tetrahedron Letters, 2013, 54(5), 414.

[00233] The compound (M-9) can be prepared, for example, according to the method described in WO 2012/083224.

Reference Process 5

[00234] A compound represented by the formula (M-8-Q1b) (hereinafter referred to as Compound (M-8-Q1b)) can be prepared according to the following scheme. [wherein X represents a chlorine atom, or a bromine atom, R3da represents a C1-C6 hydrocarbon group optionally having one or more substituents selected from Group B, a C3-C7 cycloalkyl group optionally having one or more substituents selected from Group E, a phenyl group optionally having one or more substituents selected from Group H, a five- to six-membered aromatic heterocyclic group optionally having one or more substituents selected from Group H, or a hydrogen atom, the other symbols are the same as defined above.]

[00235] This reference process comprises a step 1 for preparing a compound represented by the formula (M-10) (hereinafter referred to as Compound (M-10)) from the compound (M-9), and a step 2 for preparing compound (M-8-Q1b) from compound (M-10).

[00236] First, step 1 is explained.

[00237] The compound (M-10) can be prepared by reacting the compound (M-9) with ammonia. The reaction can be carried out according to the method described in Preparation Example 8(1) of WO 2015/002211.

[00238] Next, step 2 is explained.

[00239] The compound (M-8-Q1b) can be prepared by reacting the compound (M-10) with a compound represented by the formula (R-3) (hereinafter referred to as Compound (R-3)). The reaction can be carried out according to the method described in Process 2.

[00240] The compound (R-3) is a commercially available compound, or can be prepared according to the known method.

Reference Process 6

[00241] A compound represented by the formula (M-8-Q1d) (hereinafter referred to as Compound (M-8-Q1d)), a compound represented by the formula (M-8-Q1e) (hereinafter referred to as Compound (M-8-Q1e)), a compound represented by the formula (M-8-Q1f) (hereinafter referred to as Compound (M-8-Q1f)) and a compound represented by the formula (M-8-Q1g) ( hereinafter referred to as Compound (M-8-Q1g)) can be prepared according to the following scheme. [where, R3c represents OR12, NR11R12, NR11aR12a, NR29NR11R12, NR29OR11, NR11C(O)R13, NR29NR11C(O)R13, NR11C(O)OR14, NR29NR11C(O)OR14, NR11C(O)NR15R16, or NR 29NR11C(O) NR15R16, and the other symbols are the same as defined above.]

[00242] This reference process comprises a step 1 for preparing the compound (M-8-Q1d) and the compound (M-8-Q1e) from the compound (M-8-Q1d) as well as step 2 for preparing the compound (M-8-Q1f) and the compound (M-8-Q1g) from the compound (M-8-Q1d) and the compound (M-8-Q1e).

[00243] First, step 1 is explained.

[00244] The compound (M-8-Q1d) and the compound (M-8-Q1e) can be prepared by reacting the compound (M-8-Q1c) with N-chlorosuccinimide.

[00245] The reaction can be carried out according to the method described in PREPARATIVE EXAMPLE 60 of WO 2004/026867.

[00246] Next, the second step 2 is explained.

[00247] The compound (M-8-Q1f) can be prepared by reacting the compound (M-8-Q1d) with a compound represented by the formula (R-4) (hereinafter referred to as Compound ( R-4)) in the presence of a base. The compound (M-8-Q1g) can be prepared by reacting the compound (M-8-Q1e) with the compound (R-4) in the presence of a base.

[00248] The reaction is generally carried out in a solvent. Examples of the solvent to be used in the reaction include ethers, polar aprotic solvents, halogenated hydrocarbons, nitriles, and these mixed solvents.

[00249] A base can be added to the reaction, and examples of the base include alkali metal carbonates and alkali metal hydrides such as sodium hydride, and organic bases.

[00250] In the reaction, the base is generally used within a molar ratio range of 1 to 10, and the compound (R-4) is generally used within a molar ratio range of 1 to 10, as opposed to 1 mol of the compound (M-8-Q1d) or the compound (M-8-Q1e).

[00251] The reaction temperature is generally within a range of -20 to 150 °C. The reaction period of the reaction is generally within a range of 0.5 to 24 hours.

[00252] When the reaction is completed, water is added to the reaction mixtures, and the reaction mixtures are extracted with organic solvents, and the organic layers are prepared (such as drying and concentration) to obtain the compound (Q-8 -Q1f9 or the compound (M-8-Q1g).

[00253] Compound (R-4) is a commercially available compound, or can be prepared according to the known method.

Reference Process 7

[00254] A compound represented by the formula (M-8-Q1h) (hereinafter referred to as Compound (M-8-Q1h)) can be prepared according to the following scheme. [wherein the symbols are the same as defined above.]

[00255] This reference process comprises a step 1 for preparing a compound represented by the formula (M-11) (hereinafter referred to as Compound (M-11)) from the compound (M-9), and a step 2 for preparing compound (M-8-Q1h) from compound (M-11).

[00256] First, step 1 is explained. The compound (M11) can be prepared by reacting the compound (M-9) with hydrazine.

[00257] The reaction can be carried out according to the method described in Example 2 of WO 2013/074390.

[00258] Next, step 2 is explained. The reaction can be carried out according to the method described in process 3.

[00259] The compound represented by the formula (M-8-Q1k) and the compound represented by the formula (M-8-Q1m) can be prepared according to the following scheme. [wherein the symbols are the same as defined above.]

[00260] These reactions can be carried out according to the method described in reference process 6.

Reference Process 8

[00261] A compound represented by the formula (M-8-Q2a) (hereinafter referred to as Compound (M-8-Q2a)) can be prepared by reacting the compound (M-9) with a compound represented by the formula ( R-5) (hereinafter referred to as Composite (R-5)). [wherein the symbols are the same as defined above.]

[00262] The reaction can be carried out according to the method described in process 4.

[00263] The compound (R-5) is a commercially available compound, or can be prepared according to the known method.

Reference Process 9

[00264] A compound represented by the formula (M-8-Q2b) (hereinafter referred to as Compound (M-8-Q2b)) can be prepared by reacting a compound represented by the formula (M-10) (hereinafter , referred to as Compound (M-10)) with a compound represented by the formula (R-6) (hereinafter referred to as Compound (R-6)). [wherein the symbols are the same as defined above.]

[00265] The reaction is generally carried out in a solvent. Examples of the base to be used in the reaction include polar aprotic solvents, halogenated hydrocarbons, nitriles, alcohols, and mixtures thereof.

[00266] A base can be added to the reaction, and examples of the base include alkali metal carbonates, alkali metal hydrides and organic bases.

[00267] In the reaction, the base is generally used within a molar ratio range of 1 to 10, and the compound (R-6) is generally used within a molar ratio range of 1 to 10, as opposed to 1 mol of the compound (M-10).

[00268] The reaction temperature is generally within a range of -20 to 150 °C. The reaction period of the reaction is generally within a range of 0.5 to 24 hours.

[00269] When the reaction is completed, water is added to the reaction mixtures, and the reaction mixtures are extracted with organic solvents, and the organic layers are prepared (such as drying and concentration) to obtain the compound (M-8 -Q2b).

[00270] The compound (R-6) is a commercially available compound, or can be prepared according to the known method.

Reference Process 10

[00271] A compound represented by the formula (M-8-Q2) (hereinafter referred to as Compound (M-8-Q2c)) can be prepared by reacting the compound (M-10) with a compound represented by the formula ( R-7) (hereinafter referred to as Compound (R-7)). [wherein the symbols are the same as defined above.]

[00272] The reaction is generally carried out in a solvent. Examples of the solvent to be used in the reaction include polar aprotic solvents, halogenated hydrocarbons, nitriles, alcohols, and these mixed solvents.

[00273] A base can be added to the reaction, and examples of the base include alkali metal carbonates, alkali metal hydrides, and organic bases.

[00274] In the reaction, the base is generally used within a molar ratio range of 1 to 10, and the compound (R-7) is generally used within the molar ratio range of 1 to 10, as opposed to 1 mol of the compound (M-10).

[00275] The reaction temperature is generally within a range of -20 to 150 °C. The reaction period of the reaction is generally within a range of 0.5 to 24 hours.

[00276] When the reaction is completed, water is added to the reaction mixtures, and the reaction mixtures are extracted with organic solvents, and the organic layers are prepared (such as drying and concentration) to obtain the compound (M-8 -Q2c).

[00277] Compound (R-7) is a commercially available compound, or can be prepared according to the known method.

Reference Process 11

[00278] A compound represented by the formula (M-8-Q2e) (hereinafter referred to as Compound (M-8-Q2e)) and a compound represented by the formula (M-8-Q2f) (hereinafter referred to as Compound (M-8-Q2f)) can be prepared according to the following scheme. [wherein the symbols are the same as defined above.]

[00279] This reference process comprises a step 1 for preparing the compound (M-8-Q2e) from the compound (M11), and a step 2 for preparing the compound (M-8-Q2f) from the compound (M-8-Q2e).

[00280] First, step 1 is explained.

[00281] The compound (M-8-Q2e) can be prepared by reacting the compound (M-11) with 1,1'-carbonyldiimidazole.

[00282] The reaction can be carried out according to the method described in process 5.

[00283] Next, step 2 is explained.

[00284] The compound (M-8-Q2f) can be prepared by reacting the compound (M-8-Q2e) with a compound represented by the formula (R-9) (hereinafter referred to as Compound (R-9) ).

[00285] The reaction can be conducted according to the method described in Bioorganic and Medicinal Chemistry Letters, 2015, 25(23), 5524, WO 2005/85226, U.S. Publication No. 2012/10192, or European Publication No. 2322176.

[00286] The compound (R-9) is a commercially available compound, or can be prepared according to the known method.

Reference Process 12

[00287] The compound (M-3) can be prepared by reacting the compound (M-5) with ammonia. [wherein the symbols are the same as defined above.]

[00288] The reaction can be carried out according to the method described in reference process 5 for the preparation of compound (M-10) from compound (M-9).

Reference Process 13

[00289] The compound (M-4) can be prepared by reacting the compound (M-5) with hydrazine. [wherein the symbols are the same as defined above.]

[00290] The reaction can be carried out according to the method described in Process 3 of WO 2015/002211.

Reference Process 14

[00291] A compound represented by the formula (M-1a) (hereinafter referred to as Compound (M-1a)) can be prepared by reacting a compound represented by the formula (M-20a) (hereinafter referred to as Compound (M-20a)) with a compound represented by the formula (R-10) (hereinafter referred to as Compound (R-10)) in the presence of a base. [wherein T2 represents OR1, NR1R24, a group represented by the formula T-5, a group represented by the formula T-6, a group represented by the formula T-7, or a group represented by the formula T-8, and the other symbols are the same as defined above.]

[00292] The reaction is generally carried out in a solvent. Examples of the solvent to be used in the reaction include ethers, aromatic hydrocarbons, nitriles, polar aprotic solvents, and these mixed solvents.

[00293] Examples of the base to be used in the reaction include alkali metal carbonates and alkali metal hydrides.

[00294] In the reaction, the compound (R-10) is generally used within a molar ratio range of 1 to 2, and the base is generally utilized within a molar ratio range of 1 to 10, as opposed to 1 mol of the compound (M-20a).

[00295] The reaction temperature is generally within a range of -20 to 150 °C. The reaction period of the reaction is generally within a range of 0.5 to 24 hours.

[00296] When the reaction is completed, water is added to the reaction mixtures, and the reaction mixtures are extracted with organic solvents, and the organic layers are prepared (such as drying and concentration) to obtain the compound of the present invention.

[00297] Compound (R-10) and compound (M-20a) are commercially available compounds, or can be prepared according to the known method.

Reference Process 15

[00298] A compound represented by the formula (M-1b) (hereinafter referred to as Compound (M-1b)) can be prepared by reacting a compound represented by the formula (M-20b) (hereinafter referred to as Compound (M-20b)) with a compound represented by the formula (R-11) (hereinafter referred to as Compound (R-11)). [where T3 represents a group represented by the formula T-1, a group represented by the formula T-2, a group represented by the formula T-3, a group represented by the formula T-4, a group represented by the formula T-9, a group represented by formula T-10, a group represented by formula T-11, or a group represented by formula T-12, and the other symbols are the same as defined above.]

[00299] The reaction can be conducted by using the compound (M-20b) in place of the compound (M-1), and the compound (R-11) in place of the compound (M-2), according to the method described in process 1.

[00300] Compound (R-11) and compound (M-20b) are commercially available compounds, or can be prepared according to the known method.

Reference Process 16

[00301] A compound represented by a formula (M-1c9 (hereinafter referred to as Compound (M-1c)) can be prepared by reacting a compound represented by the formula (M-20c) (hereinafter referred to as Compound (M-20c)) with a compound represented by the formula (R-12) (hereinafter referred to as Compound (R-12)). [wherein the symbols are the same as defined above.]

[00302] Reactions can be carried out according to the method described in Preparation Example 1(1) of WO 2016/125621.

[00303] Compound (R-12) and compound (M-20c) are commercially available compounds, or can be prepared according to the known method.

Reference Process 17

[00304] A compound represented by the formula (M-1d) (hereinafter referred to as the Present compound (M-1d)) can be prepared by reacting the compound (M-20b) with a compound represented by the formula ( R-13) (hereinafter referred to as Compound (R-13)) in the presence of a copper. [wherein T4 represents a C1-C10 chain hydrocarbon group optionally having one or more halogen atoms, a (C1C5 alkoxy) C2-C5 alkyl group having one or more halogen atoms, a (C1-C5 alkylsulfanyl) C2- C5 alkyl having one or more halogen atoms, a (C1-C5 alkylsulfinyl) C2-C5 alkyl group having one or more halogen atoms, a (C1-C5 alkylsulfonyl) C2-C5 alkyl group having one or more halogen atoms, a (C3-C7 cycloalkyl) C1-C3 alkyl group having one or more substituents selected from Group G, or a C3-C7 cycloalkyl group having one or more substituents selected from Group G, and the other symbols are the same as defined above.]

[00305] The reaction is generally carried out in a solvent. Examples of the solvents to be used in the reaction include aromatic hydrocarbons, polar aprotic solvents, and these mixed solvents.

[00306] In the reaction, the compound (R-13) is generally used within a molar ratio range of 1 to 10, and copper is generally utilized within the molar ratio range of 1 to 10, as opposed to 1 mol of the compound (M-20b).

[00307] The reaction temperature is generally within a range of 40 to 200 °C. The reaction period of the reaction is generally within a range of 0.1 to 24 hours.

[00308] When the reaction is completed, water is added to the reaction mixtures, and the reaction mixtures are extracted with organic solvents, and the organic layers are prepared (such as drying and concentration) to obtain the compound (M-1d ).

[00309] The compound (R-13) is a commercially available compound, or can be prepared according to the known method.

Reference Process 18

[00310] A compound represented by the formula (M-1e) (hereinafter referred to as Compound (M-1e)) can be prepared by reacting a compound represented by the formula (M-20d) (hereinafter referred to as Compound (M-20d)) with a compound represented by a formula (R-14) (hereinafter referred to as Compound (R-14)). [wherein the symbols are the same as defined above.]

[00311] The reaction can be carried out according to the method described in Preparation Examples 6(1) of WO 2014/021468.

[00312] Compound (M-20d) and compound (R-14) are commercially available compounds, or can be prepared according to the known method.

Reference Process 19

[00313] A compound represented by the formula (M-1f) (hereinafter referred to as Compound (M-1f)) can be prepared by reacting the compound (M-20b) with a compound represented by the formula (R-15) (hereinafter referred to as Compound (R-15)) in the presence of a base. [wherein the symbols are the same as defined above.]

[00314] The reaction can be conducted according to the method described in Synthesis, 2008, 3707.

[00315] The compound (R-15) is a commercially available compound, or can be prepared according to the known method.

Reference Process 20

[00316] A compound represented by the formula (M-1g) (hereinafter referred to as Compound (M-1g)) can be prepared by reacting a compound represented by the formula (M-20e) (hereinafter referred to as Compound (M-20e)) with a compound represented by the formula (R-16) (hereinafter referred to as Compound (R-16)) in the presence of a condensing agent. [wherein the symbols are the same as defined above.]

[00317] The reaction can be carried out according to the method described in Preparation Example 6(1) of WO 2014/021468.

[00318] Compound (M-20e) and compound (R-16) are commercially available compounds, or can be prepared according to the known method.

Reference Process 21

[00319] A compound represented by the formula (M-1h) (hereinafter referred to as Compound (M-1h)) can be prepared by reacting a compound represented by the formula (M-20f) (hereinafter referred to as Compound (M-20f)) with a compound represented by the formula (R-17) (hereinafter referred to as Compound (R-17)). [wherein the symbols are the same as defined above.]

[00320] The reaction is generally carried out in a solvent. Examples of the solvent to be used in the reaction include ethers, aliphatic halogenated hydrocarbons, aromatic hydrocarbons, polar aprotic solvents, and these mixed solvents.

[00321] An acid can be added to the reaction as needed, and examples of the acid include p-toluenesulfonic acid and 10-camphorsulfonic acid.

[00322] In the reaction, the compound (R-17) is generally used within a molar ratio range of 1 to 10, and the acid is generally used within a molar ratio range of 0.1 to 10, as opposed to to 1 mol of the compound (M-20f).

[00323] The reaction temperature is generally within a range of -20 to 180 °C. The reaction period of the reaction is generally within a range of 0.1 to 24 hours.

[00324] When the reaction is completed, water is added to the reaction mixtures, and the reaction mixtures are extracted with organic solvents, and the organic layers are prepared (such as drying and concentration) to obtain the compound (M-1h ).

[00325] Compound (M-20f) and compound (R-17) are commercially available compounds, or can be prepared according to the known method.

Reference Process 22

[00326] A compound represented by the formula (M-1i) (hereinafter referred to as Compound (M-1i)) can be prepared by reacting a compound represented by the formula (M-20g) (hereinafter referred to as Compound (M-20g)) with a compound represented by the formula (R-18) (hereinafter referred to as Compound (R-18)) in the presence of a base. [wherein the symbols are the same as defined above.]

[00327] The reaction is generally carried out in a solvent. Examples of the solvent to be used in the reaction include ethers, aromatic hydrocarbons, polar aprotic solvents, and these mixed solvents.

[00328] Examples of the base to be used in the reaction include organic bases, alkali metal hydrides and alkali metal carbonates.

[00329] In the reaction, the compound (R-18) is generally used within a molar ratio range of 1 to 10, and the base is generally used within a molar ratio range of 0.1 to 5, as opposed to to 1 mol of the compound (M-20g).

[00330] The reaction temperature is generally within a range of -20 to 120 °C. The reaction period of the reaction is generally within a range of 0.1 to 24 hours.

[00331] When the reaction is completed, water is added to the reaction mixtures, and the reaction mixtures are extracted with organic solvents, and the organic layers are prepared (such as drying and concentration) to obtain the compound (M-1i ).

[00332] Compound (R-18) and compound (M-20g) are commercially available compounds, or can be prepared according to the known method.

Reference Process 23

[00333] A compound represented by the formula (M-1j) (hereinafter referred to as Compound (M-1j)), a compound represented by the formula (M-1k) (hereinafter referred to as Compound (M-1k)) , a compound represented by the formula (M-1m) (hereinafter referred to as Compound ((M-1m)) can be prepared according to the following scheme. [wherein the symbols are the same as defined above.]

[00334] This reference process comprises a step 1 for preparing a compound represented by the formula (M-21) (hereinafter referred to as Compound (M-21)) from the compound (M-20b), a step 2 for preparing a compound represented by the formula (M-22) (hereinafter referred to as Compound (M-22) from compound (M-21), a step 3 for preparing compound (M-1j) from the compound (M-22), and a step 4 for preparing the compound (M-1k) and the compound (M-1m) from the compound (M-1j).

[00335] Step 1 is explained. The compound (M-21) can be prepared by reacting the compound (M-20b) with thiobenzoic acid in the presence of a copper catalyst and a base. The reaction can be carried out according to the method described in Preparation Examples 24(4) of WO 2013/018928.

[00336] Step 2 is explained. The compound (M-22) can be prepared through hydrolysis of the compound (M-21). The reaction can be carried out according to the method described in Preparation Examples 24(5) of WO 2013/018928.

[00337] Step 3 is explained. The compound (M-1j) can be prepared by reacting the compound (M-22) with the compound (R-18) in the presence of a base. The reaction can be carried out according to the method described in process reference 22.

[00338] Step 4 is explained. Compound (M-1k) and compound (M-1m) can be prepared by oxidizing compound (M- 1j). The reaction can be carried out according to the method described in process 1 of WO 2013/018928.

[00339] Next, specific examples of the present compounds are shown below.

[00340] In this invention, Me represents a methyl group, Et represents an ethyl group, Pr represents a propyl group, i-Pr represents an isopropyl group, c-Pr represents a cyclopropyl group, c-c-Bu represents a cyclobutyl group, Ph represents a phenyl group, Py2 represents a 2-pyridyl group, Py3 represents a 3-pyridyl group. When c-Pr, F, Py2, Py3, and Py4 have any substituents, the substituents are described together with a substitution position before the symbol. For example, 4-CF3-Py2 represents a 4-(trifluoromethyl)-2-pyridyl group, and 3,5-(CF3)2-Ph represents a 3,5-bis(trifluoromethyl)phenyl group.

[00341] A compound represented by formula (L-1): wherein Z1 and Z2 each represent CH, and R3 represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Class SX1 Compound).

[00342] A compound (L-1) in which Z1 and Z2 each represent CH, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX2).

[00343] A compound (L-1) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Class SX3 Compound) .

[00344] A compound (L-1) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX4).

[00345] A compound (L-1) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX5).

[00346] A compound (L-1) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX6 ).

[00347] A compound (L-1) in which Z1 and Z2 each represent a nitrogen atom, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX7) .

[00348] A compound (L-1) in which Z1 and Z2 each represent a nitrogen atom, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX8).

[00349] A compound represented by formula (L-2): wherein Z1 and Z2 each represent CH, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX9).

[00350] A compound (L-2) in which Z1 and Z2 each represent CH, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX10).

[00351] A compound (L-2) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX11) .

[00352] A compound (L-2) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX12).

[00353] A compound (L-2) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX13).

[00354] A compound (L-2) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX14 ).

[00355] A compound (L-2) in which Z1 and Z2 each represent a nitrogen atom, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX15) .

[00356] A compound (L-2) in which Z1 and Z2 each represent a nitrogen atom, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX16).

[00357] A compound represented by formula (L-3): wherein Z1 and Z2 each represent CH, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX17).

[00358] A compound (L-3) in which Z1 and Z2 each represent CH, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX18).

[00359] A compound (L-3) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX19) .

[00360] A compound (L-3) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX20).

[00361] A compound (L-3) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX21).

[00362] A compound (L-3) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX22 ).

[00363] A compound (L-3) in which Z1 and Z2 each represent a nitrogen atom, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX23) .

[00364] A compound (L-3) in which Z1 and Z2 each represent a nitrogen atom, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX24).

[00365] A compound represented by formula (L-4): wherein Z1 and Z2 each represent CH, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX25).

[00366] A compound (L-4) in which Z1 and Z2 each represent CH, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX26).

[00367] A compound (L-4) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX27) .

[00368] A compound (L-4) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX28).

[00369] A compound (L-4) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX29).

[00370] A compound (L-4) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX30 ).

[00371] A compound (L-4) in which Z1 and Z2 each represent a nitrogen atom, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX31) .

[00372] A compound (L-4) in which Z1 and Z2 each represent a nitrogen atom, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX32).

[00373] A compound represented by formula (L-5): wherein Z4 and Z5 each represent CH2, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX33).

[00374] A compound (L-5) in which Z4 and Z5 each represent CH2, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX34).

[00375] A compound (L-5) in which Z4 represents CH2, Z5 represents C(O), and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX35) .

[00376] A compound (L-5) in which Z4 represents CH2, Z5 represents C(O), and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX36).

[00377] A compound (L-5) in which Z4 represents C(O), Z5 represents CH2, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX37) .

[00378] A compound (L-5) in which Z4 represents C(O), Z5 represents CH2, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX38).

[00379] A compound (L-5) in which Z4 represents NH, Z5 represents C(O), and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX39) .

[00380] A compound (L-5) in which Z4 represents NH, Z5 represents C(O), and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX40).

[00381] A compound (L-5) in which Z4 represents C(O), Z5 represents NH, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX41) .

[00382] A compound (L-5) in which Z4 represents C(O), Z5 represents NH, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX42).

[00383] A compound (L-5) in which Z4 represents NMe, Z5 represents C(O), and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX43) .

[00384] A compound (L-5) in which Z4 represents NMe, Z5 represents C(O), and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX44).

[00385] A compound (L-5) in which Z4 represents C(O), Z5 represents NMe, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX45) .

[00386] A compound (L-5) in which Z4 represents C(O), Z5 represents NMe, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX46).

[00387] A compound represented by formula (L-6): wherein Z4 and Z5 each represent CH2, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX47).

[00388] A compound (L-6) in which Z4 and Z5 each represent CH2, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX48).

[00389] A compound (L-6) in which Z4 represents CH2, Z5 represents C(O), and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX49) .

[00390] A compound (L-6) in which Z4 represents CH2, Z5 represents C(O), and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX50).

[00391] A compound (L-6) in which Z4 represents C(O), Z5 represents CH2, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX51) .

[00392] A compound (L-6) in which Z4 represents C(O), Z5 represents CH2, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX52).

[00393] A compound (L-6) in which Z4 represents NH, Z5 represents C(O), and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX53) .

[00394] A compound (L-6) in which Z4 represents NH, Z5 represents C(O), and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX54).

[00395] A compound (L-6) in which Z4 represents C(O), Z5 represents NH, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX55) .

[00396] A compound (L-6) in which Z4 represents C(O), Z5 represents NH, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX56).

[00397] A compound (L-6) in which Z4 represents NMe, Z5 represents C(O), and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX57) .

[00398] A compound (L-6) in which Z4 represents NMe, Z5 represents C(O), and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX58).

[00399] A compound (L-6) in which Z4 represents C(O), Z5 represents NMe, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX59) .

[00400] A compound (L-6) in which Z4 represents C(O), Z5 represents NMe, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX60).

[00401] A compound represented by formula (L-7): wherein Z4 and Z5 each represent CH2, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX61).

[00402] A compound (L-7) in which Z4 and Z5 each represent CH2, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX62).

[00403] A compound (L-7) in which Z4 represents CH2, Z5 represents C(O), and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX63) .

[00404] A compound (L-7) in which Z4 represents CH2, Z5 represents C(O), and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX64).

[00405] A compound (L-7) in which Z4 represents C(O), Z5 represents CH2, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX65) .

[00406] A compound (L-7) in which Z4 represents C(O), Z5 represents CH2, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX66).

[00407] A compound (L-7) in which Z4 represents NH, Z5 represents C(O), and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX67) .

[00408] A compound (L-7) in which Z4 represents NH, Z5 represents C(O), and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX68).

[00409] A compound (L-7) in which Z4 represents C(O), Z5 represents NH, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX69).

[00410] A compound (L-7) in which Z4 represents C(O), Z5 represents NH, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX70).

[00411] A compound (L-7) in which Z4 represents NMe, Z5 represents C(O), and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX71) .

[00412] A compound (L-7) in which Z4 represents NMe, Z5 represents C(O), and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX72).

[00413] A compound (L-7) in which Z4 represents C(O), Z5 represents NMe, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX73) .

[00414] A compound (L-7) in which Z4 represents C(O), Z5 represents NMe, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX74).

[00415] A compound represented by formula (L-8): wherein Z4 and Z5 each represent CH2, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX75).

[00416] A compound (L-8) in which Z4 and Z5 each represent CH2, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX76).

[00417] A compound (L-8) in which Z4 represents CH2, Z5 represents C(O), and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX77) .

[00418] A compound (L-8) in which Z4 represents CH2, Z5 represents C(O), and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX78).

[00419] A compound (L-8) in which Z4 represents C(O), Z5 represents CH2, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX79) .

[00420] A compound (L-8) in which Z4 represents C(O), Z5 represents CH2, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX80).

[00421] A compound (L-8) in which Z4 represents NH, Z5 represents C(O), and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX81) .

[00422] A compound (L-8) in which Z4 represents NH, Z5 represents C(O), and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX82).

[00423] A compound (L-8) in which Z4 represents C(O), Z5 represents NH, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX83).

[00424] A compound (L-8) in which Z4 represents C(O), Z5 represents NH, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX84).

[00425] A compound (L-8) in which Z4 represents NMe, Z5 represents C(O), and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX85) .

[00426] A compound (L-8) in which Z4 represents NMe, Z5 represents C(O), and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX86).

[00427] A compound (L-8) in which Z4 represents C(O), Z5 represents NMe, and R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX87) .

[00428] A compound (L-8) in which Z4 represents C(O), Z5 represents NMe, and R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX88).

[00429] A compound represented by formula (L-9): wherein Z4 and Z5 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX89).

[00430] A compound represented by formula a (L-9) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX90).

[00431] A compound represented by formula (L-9) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX91).

[00432] A compound represented by formula (L-9) in which Z1 and Z2 each represent a nitrogen atom, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX92).

[00433] A compound represented by formula (L-10): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX93).

[00434] A compound represented by the formula (L-10) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX94).

[00435] A compound represented by formula (L-10) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX95).

[00436] A compound represented by the formula (L-10) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX96).

[00437] A compound represented by formula (L-11): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX97).

[00438] A compound represented by formula (L-11) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX98).

[00439] A compound represented by formula (L-11) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX99).

[00440] A compound represented by formula (L-11) in which Z1 represents a nitrogen atom, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX100).

[00441] A compound represented by formula (L-12): wherein Z1 represents CH, Z2 represents a nitrogen atom, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX102).

[00442] A compound represented by formula (L-12) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX103).

[00443] A compound represented by formula (L-12) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX104).

[00444] A compound represented by formula (L-13): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX105).

[00445] A compound represented by formula (L-13) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX106).

[00446] A compound represented by formula (L-13) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX107).

[00447] A compound represented by formula (L-13) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX108).

[00448] A compound represented by formula (L-14): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX109).

[00449] A compound represented by formula (L-14) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX110).

[00450] A compound represented by formula (L-14) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX111).

[00451] A compound represented by formula (L-14) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX112).

[00452] A compound represented by formula (L-15): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX113).

[00453] A compound represented by formula (L-15) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX114).

[00454] A compound represented by formula (L-15) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX115).

[00455] A compound represented by formula (L-15) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX116).

[00456] A compound represented by formula (L-16): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX117).

[00457] A compound represented by formula (L-16) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX118).

[00458] A compound represented by formula (L-16) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX119).

[00459] A compound represented by formula (L-16) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX120).

[00460] A compound represented by formula (L-17): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX121).

[00461] A compound represented by formula (L-17) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX122).

[00462] A compound represented by formula (L-17) in which Z1 represents a nitrogen atom, Z2 represents CH and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX123).

[00463] A compound represented by formula (L-17) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX124).

[00464] A compound represented by formula (L-18): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX125).

[00465] A compound represented by formula (L-18) in which Z1 represents CH, Z2 represents a nitrogen atom and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX126).

[00466] A compound represented by formula (L-18) in which Z1 represents a nitrogen atom, Z2 represents CH and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX127).

[00467] A compound represented by formula (L-18) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX128).

[00468] A compound represented by formula (L-19): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX129).

[00469] A compound represented by formula (L-19) in which Z1 represents CH, Z2 represents a nitrogen atom and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX130).

[00470] A compound represented by formula (L-19) in which Z1 represents a nitrogen atom, Z2 represents CH and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX131).

[00471] A compound represented by formula (L-19) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX132).

[00472] A compound represented by the formula (L-20): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX133).

[00473] A compound represented by formula (L-20) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX134).

[00474] A compound represented by formula (L-20) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX135).

[00475] A compound represented by the formula (L-20) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX136).

[00476] A compound represented by formula (L-21): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX137).

[00477] A compound represented by formula (L-21) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX138).

[00478] A compound represented by formula (L-21) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX139).

[00479] A compound represented by formula (L-21) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX140).

[00480] A compound represented by formula (L-22): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX141).

[00481] A compound represented by formula (L-22) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX142).

[00482] A compound represented by formula (L-22) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX143).

[00483] A compound represented by formula (L-22) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX144).

[00484] A compound represented by formula (L-23): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX145).

[00485] A compound represented by formula (L-23) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX146).

[00486] A compound represented by formula (L-23) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX147).

[00487] A compound represented by formula (L-23) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX148).

[00488] A compound represented by formula (L-24): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX149).

[00489] A compound represented by formula (L-24) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX150).

[00490] A compound represented by formula (L-24) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX151).

[00491] A compound represented by formula (L-24) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX152).

[00492] A compound represented by the formula (L-25): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX153).

[00493] A compound represented by formula (L-25) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX154).

[00494] A compound represented by formula (L-25) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX155).

[00495] A compound represented by formula (L-25) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX156).

[00496] A compound represented by formula (L-26): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX157).

[00497] A compound represented by formula (L-26) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX158).

[00498] A compound represented by formula (L-26) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX159).

[00499] A compound represented by formula (L-26) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX160).

[00500] A compound represented by formula (L-27): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX161).

[00501] A compound represented by formula (L-27) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX162).

[00502] A compound represented by formula (L-27) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX163).

[00503] A compound represented by formula (L-27) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX164).

[00504] A compound represented by formula (L-28): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX165).

[00505] A compound represented by formula (L-28) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX166).

[00506] A compound represented by formula (L-28) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX167).

[00507] A compound represented by formula (L-28) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX168).

[00508] A compound represented by formula (L-29): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX169).

[00509] A compound represented by formula (L-29) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX170).

[00510] A compound represented by formula (L-29) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX171).

[00511] A compound represented by formula (L-29) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX172).

[00512] A compound represented by the formula (L-30): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX173).

[00513] A compound represented by formula (L-30) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX174).

[00514] A compound represented by formula (L-30) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX175).

[00515] A compound represented by the formula (L-30) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX176).

[00516] A compound represented by formula (L-31): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX177).

[00517] A compound represented by formula (L-31) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX178).

[00518] A compound represented by formula (L-31) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX179).

[00519] A compound represented by formula (L-31) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX180).

[00520] A compound represented by formula (L-32): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX181).

[00521] A compound represented by formula (L-32) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX182).

[00522] A compound represented by formula (L-32) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX183).

[00523] A compound represented by formula (L-32) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX184).

[00524] A compound represented by formula (L-33): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX185).

[00525] A compound represented by formula (L-33) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX186).

[00526] A compound represented by formula (L-33) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX187).

[00527] A compound represented by formula (L-33) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX188).

[00528] A compound represented by formula (L-34): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX189).

[00529] A compound represented by formula (L-34) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX190).

[00530] A compound represented by formula (L-34) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX191).

[00531] A compound represented by formula (L-34) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX192).

[00532] A compound represented by formula (L-35): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX193).

[00533] A compound represented by formula (L-35) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX194).

[00534] A compound represented by formula (L-35) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX195).

[00535] A compound represented by formula (L-35) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX196).

[00536] A compound represented by formula (L-36): wherein Z1 and Z2 each represent CH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX197).

[00537] A compound represented by formula (L-36) in which Z1 represents CH, Z2 represents a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX198).

[00538] A compound represented by formula (L-36) in which Z1 represents a nitrogen atom, Z2 represents CH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX199).

[00539] A compound represented by formula (L-36) in which Z1 and Z2 each represent a nitrogen atom, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX200).

[00540] A compound represented by formula (L-37): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX201).

[00541] A compound represented by formula (L-37) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX202).

[00542] A compound represented by formula (L-37) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX203).

[00543] A compound represented by formula (L-37) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX204).

[00544] A compound represented by formula (L-37) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX205).

[00545] A compound represented by formula (L-37) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX206).

[00546] A compound represented by formula (L-37) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX207).

[00547] A compound represented by formula (L-38): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX208).

[00548] A compound represented by formula (L-38) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX209).

[00549] A compound represented by formula (L-38) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX210).

[00550] A compound represented by formula (L-38) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX211).

[00551] A compound represented by formula (L-38) in which Z4 represents C(O), Z5 represents NH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX212).

[00552] A compound represented by formula (L-38) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX213).

[00553] A compound represented by formula (L-38) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX214).

[00554] A compound represented by formula (L-39): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX215).

[00555] A compound represented by formula (L-39) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX216).

[00556] A compound represented by formula (L-39) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX217).

[00557] A compound represented by formula (L-39) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX218).

[00558] A compound represented by formula (L-39) in which Z4 represents C(O), Z5 represents NH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX219).

[00559] A compound represented by formula (L-39) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX220).

[00560] A compound represented by formula (L-39) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX221).

[00561] A compound represented by the formula (L-40): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX222).

[00562] A compound represented by formula (L-40) where Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX223).

[00563] A compound represented by formula (L-40) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX224).

[00564] A compound represented by formula (L-40) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX225).

[00565] A compound represented by the formula (L-40) in which Z4 represents C(O), Z5 represents NH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX226).

[00566] A compound represented by formula (L-40) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX227).

[00567] A compound represented by formula (L-40) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX228).

[00568] A compound represented by formula (L-41): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX229).

[00569] A compound represented by formula (L-41) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX230).

[00570] A compound represented by formula (L-41) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX231).

[00571] A compound represented by formula (L-41) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX232).

[00572] A compound represented by formula (L-41) in which Z4 represents C(O), Z5 represents NH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX233).

[00573] A compound represented by formula (L-41) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX234).

[00574] A compound represented by formula (L-41) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX235).

[00575] A compound represented by the formula (L-42): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX236).

[00576] A compound represented by formula (L-42) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX237).

[00577] A compound represented by formula (L-42) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX238).

[00578] A compound represented by formula (L-42) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX239).

[00579] A compound represented by formula (L-42) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX240).

[00580] A compound represented by formula (L-42) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX241).

[00581] A compound represented by formula (L-42) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX242).

[00582] A compound represented by formula (L-43): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX243).

[00583] A compound represented by formula (L-43) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX244).

[00584] A compound represented by formula (L-43) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX245).

[00585] A compound represented by formula (L-43) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX246).

[00586] A compound represented by formula (L-43) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX247).

[00587] A compound represented by formula (L-43) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX248).

[00588] A compound represented by formula (L-43) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX249).

[00589] A compound represented by formula (L-44): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX250).

[00590] A compound represented by formula (L-44) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX251).

[00591] A compound represented by formula (L-44) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX252).

[00592] A compound represented by formula (L-44) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX253).

[00593] A compound represented by formula (L-44) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX254).

[00594] A compound represented by formula (L-44) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX255).

[00595] A compound represented by formula (L-44) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX256).

[00596] A compound represented by the formula (L-45): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX257).

[00597] A compound represented by formula (L-45) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX258).

[00598] A compound represented by formula (L-45) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX259).

[00599] A compound represented by formula (L-45) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX260).

[00600] A compound represented by formula (L-45) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX261).

[00601] A compound represented by formula (L-45) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX262).

[00602] A compound represented by formula (L-45) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX263).

[00603] A compound represented by formula (L-46): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX264).

[00604] A compound represented by formula (L-46) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX265).

[00605] A compound represented by formula (L-46) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX266).

[00606] A compound represented by formula (L-46) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX267).

[00607] A compound represented by formula (L-46) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX268).

[00608] A compound represented by formula (L-46) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX269).

[00609] A compound represented by formula (L-46) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX270).

[00610] A compound represented by formula (L-47): z1' where Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX271).

[00611] A compound represented by formula (L-47) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX272).

[00612] A compound represented by formula (L-47) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX273).

[00613] A compound represented by formula (L-47) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX274).

[00614] A compound represented by formula (L-47) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX275).

[00615] A compound represented by formula (L-47) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX276).

[00616] A compound represented by formula (L-47) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX277).

[00617] A compound represented by formula (L-48): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX278).

[00618] A compound represented by formula (L-48) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX279).

[00619] A compound represented by formula (L-48) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX280).

[00620] A compound represented by formula (L-48) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX281).

[00621] A compound represented by formula (L-48) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX282).

[00622] A compound represented by formula (L-48) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX283).

[00623] A compound represented by formula (L-48) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX284).

[00624] A compound represented by formula (L-49): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX285).

[00625] A compound represented by formula (L-49) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX286).

[00626] A compound represented by formula (L-49) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX287).

[00627] A compound represented by formula (L-49) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX288).

[00628] A compound represented by formula (L-49) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX289).

[00629] A compound represented by formula (L-49) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX290).

[00630] A compound represented by formula (L-49) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX291).

[00631] A compound represented by the formula (L-50): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX292).

[00632] A compound represented by the formula (L-50) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX293).

[00633] A compound represented by the formula (L-50) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX294).

[00634] A compound represented by the formula (L-50) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX295).

[00635] A compound represented by the formula (L-50) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX296).

[00636] A compound represented by the formula (L-50) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX297).

[00637] A compound represented by the formula (L-50) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX298).

[00638] A compound represented by formula (L-51): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX299).

[00639] A compound represented by formula (L-51) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX300).

[00640] A compound represented by formula (L-51) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX301).

[00641] A compound represented by formula (L-51) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX302).

[00642] A compound represented by formula (L-51) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX303).

[00643] A compound represented by formula (L-51) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX304).

[00644] A compound represented by formula (L-51) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX305).

[00645] A compound represented by the formula (L-52): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX306).

[00646] A compound represented by formula (L-52) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX307).

[00647] A compound represented by formula (L-52) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX308).

[00648] A compound represented by formula (L-51) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX309).

[00649] A compound represented by formula (L-51) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX310).

[00650] A compound represented by formula (L-52) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX311).

[00651] A compound represented by formula (L-52) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX312).

[00652] A compound represented by formula (L-53): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX313).

[00653] A compound represented by formula (L-53) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX314).

[00654] A compound represented by formula (L-53) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX315).

[00655] A compound represented by formula (L-53) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX316).

[00656] A compound represented by formula (L-53) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX317).

[00657] A compound represented by formula (L-53) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX318).

[00658] A compound represented by formula (L-53) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX319).

[00659] A compound represented by formula (L-54): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX320).

[00660] A compound represented by formula (L-54) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX321).

[00661] A compound represented by formula (L-54) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX322).

[00662] A compound represented by formula (L-54) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX323).

[00663] A compound represented by formula (L-54) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX324).

[00664] A compound represented by formula (L-54) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX325).

[00665] A compound represented by formula (L-54) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX326).

[00666] A compound represented by the formula (L-55): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX327).

[00667] A compound represented by formula (L-55) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX328).

[00668] A compound represented by formula (L-55) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX329).

[00669] A compound represented by formula (L-55) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX330).

[00670] A compound represented by formula (L-55) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX331).

[00671] A compound represented by formula (L-55) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX332).

[00672] A compound represented by formula (L-55) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX333).

[00673] A compound represented by formula (L-56): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX334).

[00674] A compound represented by formula (L-56) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX335).

[00675] A compound represented by formula (L-56) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX336).

[00676] A compound represented by formula (L-56) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX337).

[00677] A compound represented by formula (L-56) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX338).

[00678] A compound represented by formula (L-56) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX339).

[00679] A compound represented by formula (L-56) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX340).

[00680] A compound represented by formula (L-57): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX341).

[00681] A compound represented by formula (L-57) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX342).

[00682] A compound represented by formula (L-57) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX343).

[00683] A compound represented by formula (L-57) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX344).

[00684] A compound represented by formula (L-57) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX345).

[00685] A compound represented by formula (L-57) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX346).

[00686] A compound represented by formula (L-57) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX347).

[00687] A compound represented by formula (L-58): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX348).

[00688] A compound represented by formula (L-58) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX349).

[00689] A compound represented by formula (L-58) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX350).

[00690] A compound represented by formula (L-58) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX351).

[00691] A compound represented by formula (L-58) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX352).

[00692] A compound represented by formula (L-58) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX353).

[00693] A compound represented by formula (L-58) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX354).

[00694] A compound represented by the formula (L-59): Z5 where Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX355).

[00695] A compound represented by formula (L-59) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX356).

[00696] A compound represented by formula (L-59) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX357).

[00697] A compound represented by formula (L-59) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX358).

[00698] A compound represented by formula (L-59) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX359).

[00699] A compound represented by formula (L-59) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX360).

[00700] A compound represented by formula (L-59) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX361).

[00701] A compound represented by the formula (L-60): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX362).

[00702] A compound represented by the formula (L-60) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX363).

[00703] A compound represented by the formula (L-60) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX364).

[00704] A compound represented by the formula (L-60) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX365).

[00705] A compound represented by the formula (L-60) in which Z4 represents C(O), Z5 represents NH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX366).

[00706] A compound represented by formula (L-60) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX367).

[00707] A compound represented by the formula (L-60) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX368).

[00708] A compound represented by the formula (L-61): z5 where Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX369).

[00709] A compound represented by formula (L-61) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX370).

[00710] A compound represented by formula (L-61) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX371).

[00711] A compound represented by formula (L-61) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX372).

[00712] A compound represented by formula (L-61) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX373).

[00713] A compound represented by formula (L-61) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX374).

[00714] A compound represented by formula (L-61) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX375).

[00715] A compound represented by the formula (L-62): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX376).

[00716] A compound represented by formula (L-62) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX377).

[00717] A compound represented by formula (L-62) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX378).

[00718] A compound represented by formula (L-62) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX379).

[00719] A compound represented by formula (L-62) in which Z4 represents C(O), Z5 represents NH, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX380).

[00720] A compound represented by formula (L-62) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX381).

[00721] A compound represented by formula (L-62) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX382).

[00722] A compound represented by the formula (L-63): Z4'N ^z5 where Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX383).

[00723] A compound represented by formula (L-63) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX384).

[00724] A compound represented by formula (L-63) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX385).

[00725] A compound represented by formula (L-63) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX386).

[00726] A compound represented by formula (L-63) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX387).

[00727] A compound represented by formula (L-63) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX388).

[00728] A compound represented by formula (L-63) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX389).

[00729] A compound represented by the formula (L-64): wherein Z4 and Z5 each represent CH2, and R3b represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX390).

[00730] A compound represented by formula (L-64) in which Z4 represents CH2, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX391).

[00731] A compound represented by formula (L-64) in which Z4 represents C(O), Z5 represents CH2, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX392).

[00732] A compound represented by formula (L-64) in which Z4 represents NH, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX393).

[00733] A compound represented by formula (L-64) in which Z4 represents C(O), Z5 represents NH, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX394).

[00734] A compound represented by formula (L-64) in which Z4 represents NMe, Z5 represents C(O), and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX395).

[00735] A compound represented by formula (L-64) in which Z4 represents C(O), Z5 represents NMe, and R3 represents any substituents indicated in Table 7 to Table 15 (hereinafter referred to as Compound Class SX396).

[00736] A compound represented by the formula (L-65): wherein Z2 and Z3 each represent CH, R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX397).

[00737] A compound represented by formula (L-65) in which Z2 and R3 each represent CH, R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX398).

[00738] A compound represented by the formula (L-65) in which Z2 represents CH, Z3 represents a nitrogen atom, R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX399).

[00739] A compound represented by the formula (L-65) in which Z2 represents CH, Z3 represents a nitrogen atom, R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX400).

[00740] A compound represented by the formula (L-65) in which Z2 represents a nitrogen atom, Z3 represents CH, R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX401).

[00741] A compound represented by the formula (L-65) in which Z2 represents a nitrogen atom, Z3 represents CH, R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX402).

[00742] A compound represented by the formula (L-65) wherein Z2 and Z3 each represent a nitrogen atom, R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX403).

[00743] A compound represented by the formula (L-65) in which Z2 and Z3 each represent a nitrogen atom, R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX404).

[00744] A compound represented by the formula (L-66): wherein Z4 and Z5 each represent CH2, R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX405).

[00745] A compound represented by formula (L-66) wherein Z4 and Z5 each represent CH2, R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX406).

[00746] A compound represented by formula (L-66) in which Z4 represents CH2, Z5 represents C(O), R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Composite Class SX407).

[00747] A compound represented by formula (L-66) wherein Z4 represents CH2, Z5 represents C(O), R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX408).

[00748] A compound represented by formula (L-66) in which Z4 represents C(O), Z5 represents CH2, R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Composite Class SX409).

[00749] A compound represented by formula (L-66) wherein Z4 represents C(O), Z5 represents CH2, R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Composite Class SX410).

[00750] A compound represented by the formula (L-66) in which Z4 represents NH, Z5 represents C(O), R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Composite Class SX411).

[00751] A compound represented by formula (L-66) in which Z4 represents NH, Z5 represents C(O), R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX412).

[00752] A compound represented by the formula (L-66) in which Z4 represents C(O), Z5 represents NH, R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Composite Class SX413).

[00753] A compound represented by formula (L-66) in which Z4 represents C(O), Z5 represents NH, R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX414).

[00754] A compound represented by the formula (L-66) in which Z4 represents NMe, Z5 represents C(O), R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX415).

[00755] A compound represented by formula (L-66) wherein Z4 represents NMe, Z5 represents C(O), R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX416).

[00756] A compound represented by the formula (L-66) in which Z4 represents C(O), Z5 represents NMe, R3b represents a hydrogen atom, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX417).

[00757] A compound represented by formula (L-66) wherein Z4 represents C(O), Z5 represents NMe, R3b represents a trifluoromethyl group, and T represents any substituents indicated in Table 1 to Table 6 (hereinafter referred to as Compound Class SX417).

[00758] A compound represented by formula (L-67): wherein Zx1, Zx2 and Zx3 each represent any combinations of the substituents indicated in Table 16 and Table 17 (hereinafter referred to as Compound Class SX419). [Table 16]

[00759] A compound represented by formula (L-68): wherein Zx1, Zx2 and Zx3 each represent any combinations of the substituents indicated in Table 16 and Table 17 (hereinafter referred to as Compound Class SX420).

[00760] A compound represented by the formula (L-69): wherein Zx3, Zx4 and Zx5 each represent any combinations of the substituents indicated in Table 18 (hereinafter referred to as Compound Class SX421). [Table 18]

[00761] A compound represented by the formula (L-70): wherein Zx3, Zx4 and Zx5 each represent any combinations of the substituents indicated in Table 18 (hereinafter referred to as Compound Class SX422).

[00762] The compound of the present invention can be mixed or combined with one or more ingredients selected from a group consisting of the following Group (a), Group (b), Group (c), Group (d) and Group (e) (hereinafter referred to as "Present ingredient").

[00763] The above-mentioned mixture or combination represents a use of the compound Gift and the ingredient Gift at the same time, separately or at certain intervals.

[00764] When the present compound and the present ingredient are used at the same time, the present compound and the present ingredient may be contained in separate formulations respectively, or may be contained in the same formulation.

[00765] One aspect of the present invention is a composition comprising one or more ingredients selected from Group (a), Group (b), Group (c), Group (d) and Group (e) (i.e., Present ingredient) as well as the compound Present.

[00766] Group (a) represents a group of insecticidal ingredients, a group of miticide ingredients, or a group of nematicide ingredients, which is selected from the group consisting of the following subgroup a-1 to subgroup a-10.

[00767] Subgroup a-1: carbamate acetylcholineesterase (AChE) inhibitors

[00768] Subgroup a-2: organophosphorus acetylcholineesterase (AChE) inhibitors

[00769] Subgroup a-3: GABA-activated chloride channel blockers

[00770] Subgroup a-4: GABA-activated chloride channel allosteric modulators

[00771] Subgroup a-5: sodium channel modulators

[00772] Subgroup a-6: competitive modulators of the nicotinic acetylcholine receptor (nAChR)

[00773] Subgroup a-7: ryanodine receptor modulators

[00774] Subgroup a-8: microbial materials

[00775] Subgroup a-9: nematicidal ingredients

[00776] Subgroup a-10: The other group as insecticidal active ingredients and miticidal active ingredients

[00777] Group (b) represents a group of fungicidal active ingredient selected from the group consisting of the following subgroup b-1 to subgroup b-18.

[00778] Subgroup b-1: PA fungicides (Phenyl amide)

[00779] Subgroup b-2: MBC fungicides (methyl benzimidazole carbamate)

[00780] Subgroup b-3: Thiazole carboxamides

[00781] Subgroup b-4: SDHI (succinate dehydrogenase inhibitors)

[00782] Subgroup b-5: QoI fungicides (Qo Inhibitors)

[00783] Subgroup b-6: QiI fungicides (Qi Inhibitors)

[00784] Subgroup b-7: Thiophene carboxamides

[00785] Subgroup b-8: AP fungicides (Anilinopyrimidine)

[00786] Subgroup b-9: PP (Phenylpyrrole) fungicides

[00787] Subgroup b-10: AH fungicides (Aromatic hydrocarbons)

[00788] Subgroup b-11: DMI fungicides (demethylation inhibitors)

[00789] Subgroup b-12: CCA (carboxylic acid amide) fungicides

[00790] Subgroup b-13: Piperidinyl thiazole isoxazoline

[00791] Subgroup b-14: Tetrazolyl oxime

[00792] Subgroup b-15: Dithiocarbamate

[00793] Subgroup b-16: Phthalimide

[00794] Subgroup b-17: microbial fungicides

[00795] Subgroup b-18: Other fungicides

[00796] Group (c) represents a group of plant growth modulation ingredients selected from the group consisting of the following subgroup c-1, subgroup c-2 and subgroup c-3.

[00797] Subgroup c-1: plant growth modulating compounds

[00798] Subgroup c-2: group of fungi of the genus Mycorrhizal

[00799] Subgroup c-3: group of root nodule bacteria

[00800] Group (d) represents a group of phytotoxicity reducing ingredients.

[00801] Group (e) represents a synergistic group.

[00802] The composition comprising the present ingredient and the present above-mentioned compound may exert an effect of the composition depending on the contents or the ratio of contents of the present above-mentioned ingredients or the present above-mentioned compound in the above-mentioned composition. Accordingly, the use of the above-mentioned composition can be decided depending on the effect that is produced by the above-mentioned composition. The above-mentioned composition may have one or two or more applied uses.

[00803] One embodiment of the above-mentioned composition is an agrochemical composition.

[00804] Likewise, another embodiment of the above-mentioned composition is an insecticidal, miticidal or nematicidal composition.

[00805] Also, another embodiment of the aforementioned composition is a fungicidal composition.

[00806] Furthermore, another modality of the above-mentioned composition is a plant growth modulating composition.

[00807] Also, another embodiment of the above-mentioned composition is a phytotoxicity-reducing composition.

[00808] Examples of the combination of the present ingredient and the present compound are described below. For example, alanicarb + SX means a combination of alanicarb and SX.

[00809] The "SX" symbol represents any of the present compound selected from the Class SX1 compound through the Class SX422 compound. Likewise, all of the present ingredients mentioned below are known ingredients, and are commercially available or can be produced by a known method. If the present ingredient is a bacteria, it is available from the bacterial authority depository. The numeric figure in parentheses represents a CAS registration number.

[00810] Examples of the combination of the Present ingredient of the above subgroup a-1 and the Present compound:

[00811] alanicarb + SX, aldicarb + SX, bendiocarb + SX, benfura- carb + SX, butocarboxim + SX, butoxycarboxim + SX, carbaryl: NAC + SX, carbofuran + SX, carbosulfan + SX, ethiofencarb + SX, fenobu- carb : BPMC + SX, formetanate + SX, furatiocarb + SX, isoprocarb: MIPC + SX, methiocarb + SX, methomyl + SX, metolcarb + SX, oxamyl + SX, pirimicarb + SX, propoxur: FC + SX, tiodicarb + SX, tiofanox + SX, triazamate + SX, trimetacarb + SX, XMC + SX, xylylcarb + SX.

[00812] Examples of the combination of the Present ingredient of the above subgroup a-2 and the Present compound:

[00813] acephate + SX, azamethiphos + SX, azinphos-ethyl + SX, azinphos-methyl + SX, cadusafos + SX, chlorethoxyphos + SX, chlorfenvinphos + SX, chlormephos + SX, chlorpyrifos + SX, chlorpyrifos-methyl + SX, coumaphos + SX, cyanophos: CYAP + SX, demeton-S-methyl + SX, diazinon + SX, dichlorvos: DDVP + SX, dicrotophos + SX, dimethoate + SX, dimethylvinphos + SX, disulfoton + SX, EPN + SX, ethion + SX, etoprofos + SX, fanfur + SX, fenamiphos + SX, fenitrothion: MEP + SX, fenthion: MPP + SX, fos- thiazate + SX, heptenophos + SX, imiciaphos + SX, isofenfos + SX, isoprop- yl-O -(methoxyaminothiophosphoryl)salicylate + SX, isoxathione + SX, malathion + SX, mecarbam + SX, methamidophos + SX, methidathione: DMTP + SX, mevinphos + SX, monocrotophos + SX, naled: BRP + SX, omethoate + SX, oxidemeton- methyl + SX, parathion + SX, parathion-methyl + SX, phento-ate: PAP + SX, phorate + SX, fosalone + SX, phosmet: PMP + SX, phosphamidone + SX, phoxim + SX, pirimiphos-methyl + SX, profenofos + SX, propetanphos + SX, prothiophos + SX, pyraclofos + SX, pyridafenthion + SX, quinalphos + SX, sulfotep + SX, tebupirinphos + SX, temephos + SX, terbufos + SX, tetrachlorvinphos + SX, thiometon + SX, triazophos + SX, trichlorfon: DEP + SX, vamidothione + SX.

[00814] Examples of the combination of the Present ingredient of the subgroup above a-3 and the Present compound:

[00815] etiprol + SX, fipronil + SX, flufiprol + SX, chlordane + SX, endosulfan + SX, alpha-endosulfan + SX.

[00816] Examples of the combination of the Present ingredient of the above subgroup a-4 and the Present compound:

[00817] afoxolaner + SX, fluralaner + SX, broflanilide + SX, fluxametamide + SX.

[00818] Examples of the combination of the Present ingredient of the above subgroup a-5 and the Present compound:

[00819] acrinathrin + SX, allethrin + SX, bifenthrin + SX, capa-fifenthrin + SX, bioalethrin + SX, bioresmethrin + SX, cycloprothrin + SX, cyfluthrin + SX, beta-cyfluthrin + SX, cyhalothrin + SX, gamma-cyhalothrin + SX, lambda-cyhalothrin + SX, cypermethrin + SX, alpha-cypermethrin + SX, beta-cypermethrin + SX, theta-cypermethrin + SX, zeta-cypermethrin + SX, cyphenothrin + SX, deltamethrin + SX, empentrin + SX, esfenvale - rat + SX, etofenprox + SX, fenpropatrin + SX, fenvalerate + SX, flucitrinate + SX, flumethrin + SX, fluvalinate + SX, tau-fluvalinate + SX, halfenprox + SX, heptafluthrin + SX, imiprothrin + SX, kadethrin + SX, meperfluthrin + SX, monfluorothrin + SX, permethrin + SX, fenothrin + SX, pralethrin + SX, pyrethrins + SX, resmethrin + SX, silafluofen + SX, tefluthrin + SX, capa-tefluthrin + SX, tetramethrin + SX, tetramethylflutri - na + SX, tralomethrin + SX, transfluthrin + SX, benfluthrin + SX, flufenoprox + SX, flumethrin + SX, sigma-cypermethrin + SX, furamethrin + SX, metofluthrin + SX, profluthrin + SX, dimefluthrin + SX, epsilon - metofluthrin + SX, epsilon-monfluorothrin + SX, methoxychlor + SX.

[00820] Examples of the combination of the Present ingredient of the above subgroup a-6 and the Present compound:

[00821] acetamiprid + SX, clothianidin + SX, dinotefuran + SX, imi-dacloprid + SX, nitenpyram + SX, thiacloprid + SX, thiamethoxam + SX, sul-foxaflor + SX, flupyradifurone + SX, triflumezopyrim + SX, dichloromezothiaz + SX , cycloxaprid + SX, (E)-N-{1- [(6-chloropyridin-3-yl)methyl]pyridine-2(1H)-ylidene}-2,2,2-trifluoroacetamide (1689566-03-7) +SX.

[00822] Examples of the combination of the Present ingredient of the subgroup above a-7 and the Present compound:

[00823] chlorantraniliprol + SX, cyantraniliprol + SX, cycloniliprol + SX, flubendiamide + SX, tetraniliprol + SX, cyalodiamide + SX, 3-bromo-N- [2,4-dichloro-6-(methylcarbamoyl)phenyl]-1- (3,5-dichloropyridin-2-yl)-1H-pyrazol-5-carboxamide (1104384-14-6) + SX.

[00824] Examples of the combination of the Present ingredient of the above subgroup a-8 and the Present compound:

[00825] Beauty firmus + SX, Bacillus megaterium + SX, Hirsutella rhossiliensis + SX, Hirsutella minnesotensis + SX, Monacrosporium phymatopagus + SX, Pasteuria nishizawae + SX, Pasteuria penetrans + SX, Pasteuria usgae + SX, Verticillium chlamydosporium + SX.

[00826] Examples of the combination of the Present ingredient of the above subgroup a-9 and the Present compound:

[00827] abamectin + SX, fluazaindolizine + SX, fluensulfone + SX, fluopyram + SX, thioxazafen + SX.

[00828] Examples of the combination of the Present ingredient of the above subgroup a-10 and the Present compound:

[00829] spinetoram + SX, spinosad + SX, emamectin-benzoate + SX, lepimectin + SX, milbemectin + SX, hydroprene + SX, quinoprene + SX, methoprene + SX, fenoxycarb + SX, pyriproxyfen + SX, methyl bromide + SX, chloropicrin + SX, sulfuryl fluoride + SX, sodium aluminum fluoride or chiolite + SX, borax + SX, boric acid + SX, disodium octaborate + SX, sodium borate + SX, sodium metaborate + SX, tartar emetic + SX, dazomet + SX, metam + SX, pymetrozine + SX, pyrifluquinazone + SX, clofentezine + SX, hexithiazox + SX, diflovidazin + SX, etoxazole + SX, diafenthiuron + SX, azocyclotine + SX, ciexatin + SX, fenbutatin oxide + SX, propargite + SX, tetradifon + SX, chlorfenapyr + SX, DNOC + SX, sulfluramid + SX, bensultap + SX, Cartap + SX, Cartap hydrochloride + SX, thiocyclam + SX, tiosultap-disodium + SX, tiosultap- monosodium + SX, bistrifluron + SX, chlorfluazuron + SX, diflubenzuron + SX, fluazuron + SX, flucicloxuron + SX, flufenoxuron + SX, hexaflumuron + SX, lufenuron + SX, novaluron + SX, noviflumuron + SX, teflubenzuron + SX, triflumuron + SX, buprofezin + SX, ciromazine + SX, cromafenozide + SX, halofenozide + SX, methoxyfenozide + SX, tebufenozide + SX, amitraz + SX, hydramethylnon + SX, acequinocil + SX, fluacripyrim + SX, bifenazate + SX, fenazaquin + SX, fenpyroximate + SX, pyridaben + SX, pyrimidifen + SX, tebufenpyrad + SX, tolfenpyrad + SX, rotenone + SX, indoxacarb + SX, metaflumizone + SX, spirodiclofen + SX, spiromesifen + SX, spirotetramat + SX, aluminum phosphide + SX, calcium phosphide + SX, phosphine + SX, zinc phosphide + SX, calcium cyanide + SX, potassium cyanide + SX, sodium cyanide + SX, cyenopirafen + SX, cyflumetofen + SX, piflubumide + SX, flonicamid + SX, azadirachtin + SX, benzoximate + SX, bromopropylate + SX, quinomethionate + SX, dicofol + SX, pyridalyl + SX, lime sulfur + SX, sulfur + SX, machine oil + SX, nicotine + SX, nicotine-sulfate + SX, afidopiropen + SX, flometoquin + SX, methoxadiazone + SX, pyriminostrobin + SX, N- [3-chloro-1-(pyridin-3-yl)-1H- pyrazol-4-yl ]-N-ethyl-3-(3,3,3-trifluoropropylsulfanyl)propanamide (147791927-9) + SX, N-[3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl ]-N-ethyl-3-(3,3,3-trifluoropropanesulfinyl)propanamide (1477923-37-7) + SX, 5-(1,3-dioxan-2-yl)-4-[4-(trifluoromethyl) benzyloxy]pyrimidine (1449021-97-9) + SX, 2- [3-(ethanesulfonyl)pyridin-2-yl]-5-(trifluoromethanesulfonyl)-benzoxazole (1616678-32-0) + SX, 4- [5- (3,5-dichlorophenyl)-5-(trifluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-2-methyl-N-(1-oxothietan-3-yl)benzamide (1241050- 20-3) + SX, 3-methoxy-N-(5-{5-(trifluorophenyl)-5-[3-(trifluorophenyl)phenyl]-4,5-dihydro-1,2-oxazol-3-yl} indan-1-yl)propanamide (1118626-57-5) + SX, 3-(4-chloro-2,6-dimethylphenyl)-4-[(ethoxycarbonyl)oxy]-8-methoxy-1-methyl-1, 8- diazaspiro [4,5]deca-3-en-2-one (1229023-00-0) + SX, N- [2-bromo-6- chloro-4-(1,1,1,2,3 ,3,3-heptafluropropan-2-yl)phenyl]-3- [ethyl- [(pyridin-4-yl)carbonyl]amino}-2-methoxybenzamide (1429513-53-0) + SX, N- [2- bromo-6-chloro-4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)phenyl]-3-[ethyl-(4-cyanobenzoyl)amino]-2-methoxybenzamide (1609007 -65-9) + SX, N-[2-bromo-6-difluoromethoxy-4-(1,1,1,2,3,3,3-heptafluropropan-2-yl)phenyl]-3-{methyl [ pyridin-4-yl)carbonyl]amino}-2-methoxybenzamide (1630969-78-6) + SX, 1-{2-fluroro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]phenyl }-3-(trifluorophenyl)- 1H-1,2,4-triazol-5-amine (885026-50-6) + SX, and 3-endo- [2-propoxy-4- (trifluorophenyl)phenoxy]-9 -{[5-(trifluorophenyl)pyridin-2-yl]oxy}-9-azacyclo[3,3,1]nonane (1332838-17-1) + SX.

[00830] Examples of the combination of the present active ingredient of the above subgroup b-1 and the present compound:

[00831] benalaxyl + SX, benalaxyl-M + SX, furalaxyl + SX, metalaxyl + SX, metalaxyl-M + SX, oxadixyl + SX, ofurace + SX.

[00832] Examples of the combination of the present active ingredient of the above subgroup b-2 and the present compound:

[00833] benomyl + SX, carbendazim + SX, fuberidazole + SX, thiabendazole + SX, thiophanate + SX, thiophanate-methyl + SX.

[00834] Examples of the combination of the present active ingredient of the above subgroup b-3 and the present compound:

[00835] etaboxam + SX.

[00836] Examples of the combination of the present active ingredient of the above subgroup b-4 and the present compound:

[00837] benodanil + SX, flutolanil + SX, mepronil + SX, isofetamid + SX, fenfuram + SX, carboxine + SX, oxycarboxine + SX, thifluzamide + SX, benzovindiflupyr + SX, bixafen + SX, fluxapyroxad + SX, furametpyr + SX , isopyrazam + SX, penflufen + SX, penthiopyrad + SX, sedaxane + SX, pidiflumetofen + SX, boscalid + SX, pyraziflumid + SX, 3-difluoromethyl-N-methoxy-1-methyl-N- [(1R)-1- methyl-2-(2,4,6-trichlorophenyl)ethyl]pyrazol-4-carboxamide (1639015-48-7) + SX, 3-difluoromethyl-N-methoxy-1-methyl-N-[(1S)-1 -methyl-2-(2,4,6-trichlorophenyl)ethyl]pyrazol-4-carboxamide (1639015-49-8) + SX, N-cyclopropyl-3-(difluoromethyl)-5-fluoro-N-(5- chloro-2-isopropylbenzyl)-1-methyl-1H-pyrazol-4-carboxamide (1255734-28-1) + SX, 3-difluoromethyl-1-methyl-N-(1,1,3-trimethylindan-4-yl )pyrazol-4-carboxamide (141573-94-6) + SX, 3-difluoromethyl-1-methyl-N-[(3R)-1,1,3-trimethylindan-4-yl]pyrazol-4-carboxamide (1352994 -67-2) + SX, 3-difluoromethyl-N-(7-fluoro-1,1,3-trimethylindan-4-yl)-1-methylpyrazol-4-carboxamide (1383809-87-7) + SX, 3 -difluoromethyl-N-[(3R)-7-fluoro-1,1,3-trimethylindan-4-yl]-1-methylpyrazol-4-carboxamide (1513466-73-3) + SX.

[00838] Examples of the combination of the present active ingredient of the above subgroup b-5 and the present compound:

[00839] azoxystrobin + SX, coumoxystrobin + SX, enoxastrobin + SX, fluphenoxystrobin + SX, picoxystrobin + SX, pyraoxystrobin + SX, mandestrobin + SX, pyraclostrobin + SX, pyramethostrobin + SX, triclopiricarb + SX, kresoxim-methyl + SX , trifloxystrobin + SX, dimoxystrobin + SX, phenaminstrobin + SX, metominostrobin + SX, orisastrobin + SX, famoxadone + SX, fluoxastrobin + SX, fenamidone + SX, piribencarb + SX.

[00840] Examples of the combination of the present active ingredient of the above subgroup b-6 and the present compound:

[00841] ciazofamid + SX, amisulbrom + SX, binapacril + SX, meptildinocap + SX, dinocap + SX, fluazinam + SX.

[00842] Examples of the combination of the present active ingredient of the above subgroup b-7 and the present compound:

[00843] siltiofam + SX.

[00844] Examples of the combination of the present active ingredient of the above subgroup b-8 and the present compound:

[00845] cyprodinil + SX, mepanipyrim + SX, pyrimethanil + SX.

[00846] Examples of the combination of the present active ingredient of the above subgroup b-9 and the present compound:

[00847] fenpiclonil + SX, fludioxonil + SX.

[00848] Examples of the combination of the present active ingredient of the above subgroup b-10 and the present compound:

[00849] biphenyl + SX, cloroneb + SX, dichloran + SX, quintazene + SX, tecnazene + SX, tolclofos-methyl + SX.

[00850] Examples of the combination of the present active ingredient of the above subgroup b-11 and the present compound:

[00851] azaconazole + SX, bitertanol + SX, bromuconazole + SX, ci-proconazole + SX, difenoconazole + SX, diniconazole + SX, diniconazole—M + SX, epoxiconazole + SX, etaconazole + SX, fenbuconazole + SX, fluquinconazole + SX, flusilazole + SX, flutriafol + SX, hexaconazole + SX, imibenconazole + SX, ipconazole + SX, ipfentrifluconazole + SX, mefentrifluconazole + SX, metconazole + SX, myclobutanil + SX, penconazole + SX, propiconazole + SX, simeconazole + SX, tebuconazole + SX, tetraconazole + SX, triadimefon + SX, triadimenol + SX, triticonazole + SX, prothioconazole + SX, triforin + SX, pyrifenox + SX, pyrisoxazole + SX, fenarimol + SX, nuarimol + SX , imazalil + SX, oxpoconazole + SX, oxpoconazole fumarate + SX, pefurazoate + SX, prochloraz + SX, triflumizole + SX.

[00852] Examples of the combination of the present active ingredient of the above subgroup b-12 and the present compound:

[00853] dimetomorph + SX, flumorph + SX, pirimorph + SX, bentiavalicarb + SX, bentivalicarb-isopropyl + SX, iprovalicarb + SX, valifenalate + SX, mandipropamid + SX.

[00854] Examples of the combination of the present active ingredient of the above subgroup b-13 and the present compound:

[00855] oxathiapiproline + SX.

[00856] Examples of the combination of the present active ingredient of the above subgroup b-14 and the present compound:

[00857] picarbutrazox + SX.

[00858] Examples of the combination of the present active ingredient of the above subgroup b-15 and the present compound:

[00859] ferbam + SX, mancozeb + SX, maneb + SX, metiram + SX, propineb + SX, tiram + SX, zineb + SX, ziram + SX.

[00860] Examples of the combination of the present active ingredient of the above subgroup b-16 and the present compound:

[00861] Captan + SX, Captafol + SX, Folpet + SX.

[00862] Examples of the combination of the present active ingredient of the above subgroup b-17 and the present compound:

[00863] strains of Agrobacterium radiobactor (such as its strain 84) + SX, Bacillus amyloliquefaciens + SX, strain of Bacillus amyloliquefaciens QST713 + SX, strain of Bacillus amyloliquefaciens FZB24 + SX, strain of Bacillus amyloliquefaciens MBI600 + SX, strain of Bacillus amyloliquefaciens D747 + SX, Bacillus amyloliquefaciens strain AT332 + SX, Bacillus amyloliquefaciens strain PTA4838 + SX, Bacillus pumilus + SX, Bacillus simplex strain CGF2856 (such as its strain CGF2856) + SX, Bacillus subtilis + SX, strain of Bacillus subtilis QST713 + SX, Bacillus subtilis strain HAI0404 + SX, Bacillus subtilis strain Y1336 + SX, strains of Variovorax paradoxus (such as its strain CGF4526) + SX, strains of Erwinia carotovora (such as its strain CGE234M403) + SX , strains of Pseudomonas fluorescens strains (such as its strain G7090) + SX, strains of Talaromyces flavus (such as its strain SAY-Y-94-01) + SX, strain of Trichoderma atroviride (such as its strain SKT-1), Trichoderma harzianum + SX strains, Harpin + SX protein.

[00864] Examples of the combination of the present active ingredient of the above subgroup b-18 and the present compound:

[00865] bupyrimate + SX, dimetirimol + SX, ethyrymol + SX, himexazol + SX, octilinone + SX, oxolinic acid + SX, diethofencarb + SX, zoxamide + SX, pencicuron + SX, fluopicolide + SX, fenamacril + SX, diflumethorim + SX, tolfenpyrad + SX, fentin acetate + SX, fentin chloride + SX, fentin hydroxide + SX, ametoctradin + SX, blasticidin-S + SX, kasugamycin + SX, streptomycin + SX, oxytetracycline + SX, quinoxifene + SX, proquinazid + SX, clozolinate + SX, dimethaclone + SX, iprodione + SX, procymidone + SX, vinclozolin + SX, edifenfos + SX, iprobenfos + SX, pyrazofos + SX, isoprothiolane + SX, etridiazole + SX, iodocarb + SX, propamocarb + SX, prothiocarb + SX, aldimorph + SX, dodemorph + SX, fenpropidine + SX, fenpropimorph + SX, piperaline + SX, spiroxamine + SX, tridemorph + SX, fenexamide + SX, fenpyrazamine + SX, piributicarb + SX, naftifine + SX, terbinafine + SX, polyoxins + SX, phthalide + SX, pyroquilone + SX, tricyclazole + SX, carpropamide + SX, diclocimet + SX, fenoxanil + SX, tolprocarb + SX, acibenzolar-S-methyl + SX, probenazol + SX, thiadinyl + SX, isothianyl + SX, laminarin + SX, cymoxanil + SX, fosetyl + SX, tecloftalam + SX, triazoxide + SX, flusulfamide + SX, diclomezine + SX, metasulfocarb + SX, ciflufenamid + SX, metrafenone + SX, pyriofenone + SX, dodine + SX, flutianil + SX, ferinzone + SX, tebufloquin + SX, validamycin + SX, basic copper chloride + SX, copper(II) hydroxide + SX, basic copper sulfate + SX, bisethylenediamine copper[II] salt of dodecylbenzenesulfonic acid (DBEDC) + SX, organocopper + SX, sulfur + SX, chlorothalonil + SX, diclofluanid + SX, tolylfluanid + SX, guazatine + SX, iminoctadine + SX, anylazine + SX, dithianon + SX, cinomethionat + SX, fluoroimide + SX, dipimetitron + SX, quinofumelin + SX, diclobentiazox + SX, 3-chloro-5-phenyl-6-methyl-4-(2,6-difluorophenyl)pyridazine ( 1358061-55-8) + SX, fenpicoxamide + SX, N'- [4-({3- [(4-chlorophenyl)methyl]-1,2,4-thiadiazol-5-yl}oxy-2,5- dimethylphenyl]-N-ethyl-N-methylmethanomidamide (1202781-91-6) + SX, 2-{3- [2-(1-{ [3,5-bis(difluoromethyl)-1H-pyrazol-1-yl] acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenyl=methanesulfonate (1360819-11-9) + SX, 4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine (1362477-26-6) + SX, 2 ,2-dimethyl-9-fluoro-5-(quinolin-3-yl)-2,3-dihydrobenzo [f] [1,4]oxazepine (1207749-50-5) + SX, 2- [6-(3 -fluoro-4-methoxyphenyl)-5-methylpyridin-2-yl]quinazoline (1257056-97-5) + SX, 5-fluoro-2-[(4-methylphenyl)methoxy]-4-pyrimidinamine (1174376-25- 0) + SX, 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidine-2(1H)-one (161666498-2) + SX, N'-(2,5-dimethyl -4-phenoxyphenyl)-N-ethyl-N-methyl- methanoimidamide (1052688-31-9) + SX, N'-{4- [(4,5-dichlorothiazol-2-yl)oxy]-2,5- dimethylphenyl}-N-ethyl-N-methyl-methanomidamide (929908-57-6) + SX, (2Z)-3-amino-2-cyano-3-phenylacrylate ethyl (39491-78-6) + SX, N - {(2-chlorothiazol-5-yl)methyl}-N-ethyl-6-methoxy-3-nitropyridine-2-amine (1446247-98-8) + SX, 1- [2-({ [1-( 4-chlorophenyl)-1H-pyrazol-3-yl]oxy}methyl)-3-methylphenyl]-4-methyl-5-oxo-4,5-dihydro-1H-tetrazol (1472649-01-6) + SX.

[00866] Examples of the combination of the present active ingredient of the above subgroup c-1 and the present compound:

[00867] ethephon + SX, chlormequat + SX, chlormequat-chloride + SX, mepiquat + SX, mepiquat-chloride + SX, Gibberellin A3 + SX, abscisic acid + SX, Kinetin + SX, benzyladenine + SX, forchlorfenuron + SX, thidiazuron +SX.

[00868] Examples of the combination of the present active ingredient of the above subgroup c-2 and the present compound:

[00869] Glomus spp. + SX, Glomus intraradices + SX, Glomus mosseae + SX, Glomus aggregatum + SX, Glomus etunicatum + SX.

[00870] Examples of the combination of the present active ingredient of the above subgroup c-3 and the present compound:

[00871] Bradyrhizobium elkani + SX, Bradyrhizobium japonicum + SX, Bradyrhizobium lupini + SX, Rhizobium leguminosarum bv. trifolii + SX, Rhizobium leguminosarum bv. phaseoli + SX, Rhizobium leguminosarum bv. viciae + SX, Sinorhizobium meliloti + SX, Rhizobium spp. +SX.

[00872] Examples of the combination of the present active ingredient of the subgroup above d and the present compound:

[00873] benoxacor + SX, cloquintocet-mexil + SX, ciometrinil + SX, dichlormid + SX, fenchlorazol-ethyl + SX, fenclorim + SX, flurazol + SX, furilazol + SX, mefenpyr-diethyl + SX, MG191 (2-( dichloromethyl)-2-methyl-1,3-dioxolane) + SX, oxabetrinil + SX, alidochlor + SX, isoxadifen-ethyl + SX, cyprosulfamide + SX, fluxofenim + SX, 1,8-naphthalic anhydride + SX, AD-67 (4-(dichloroacetyl)-1-oxa-4-azaspiro [4,5] decane) + SX.

[00874] Examples of the combination of the present active ingredient of the subgroup above and the present compound:

[00875] DMC (1,1-bis(4-chlorophenyl)ethanol) + SX, FDMC (1,1-bis(4-chlorophenyl)-2,2,2-trifluoroethanol) + SX, bucarpolate + SX, N, N-dibutyl-4-chlorobenzenesulfonamide + SX, dietholate + SX, diethylmaleate + SX, 1-dodecyl-1H-imidazole + SX, N-(2-ethylhexyl)-8,9,10-trinorborn-5-ene-2, 3- dicarboximide + SX, PSCP (cyclic phenylsaligenin phosphate) + SX, piperonyl butoxide + SX, piperonyl cyclonene + SX, piprotal + SX, propyl isoma + S, safroxan + SX, sesamex + SX, sesamolin + SX , sulfoxide + SX, tribufos + SX, TBPT (S,S,S- tributyl phosphorotrithioate) + SX, ETP (1,1,1-trichloro-2,3-expoxypropane) + SX, ETN (1,2 -epoxy- 1,2,3,4-tetrahydronaphthalene) + SX, TPP (triphenyl phosphate) + SX, Verbutin + SX.

[00876] Examples of harmful arthropods on which the compound of the present invention is effective include harmful insects and harmful mites. Specific examples of harmful arthropods include the following.

[00877] Hemiptera pests:

[00878] Delphacidae (e.g., Laodelphax striatellus, Nilaparvata lugens, Sogatella furcifera, Peregrinus maidis, Javesella pellucida, Perkinsiella saccharicida or Tagosodes orizicolus);

[00879] Cicadellidae (e.g., Nephotettix cincticeps, Nephotettix virescens, Nephotettix nigropictus, Recilia dorsalis, Empoasca onukii, Empoasca fabae, Dalbulus maidis or Cofana spectra);

[00880] Cercopidae (for example, Mahanarva posticata or Mahanarva fimbriolata);

[00881] Aphididae (e.g., Aphis fabae, Aphis glycines, Aphis gossypii, Aphis pomi, Aphis spiraecola, Myzus persicae, Brachycaudus helichrysi, Brevicoryne brassicae, Pink apple aphid (Dysaphis plantaginea), Lipaphis erysimi, Macrosiphum euphorbiae, Aulacorthum solani, Nasonovia ribisnigri, Rhopalosiphum padi, Rhopalosiphum maidis, Toxoptera citricidus, Hyalopterus pruni, Melanaphis sacchari, Tetraneura nigriabdominalis, Ceratovacuna lanigera or Eriosoma lanigerum);

[00882] Phylloxeridae (e.g., Daktulosphaira vitifoliae, Pecan phylloxera (Phylloxera devastatrix), Pecan leaf phylloxera (Phylloxera Notabilis) or Southern Pecan leaf phylloxera (Phylloxera russellae));

[00883] Adelgidae (for example, Adelges tsugae, Adelges piceae or Aphrastasia pectinatae);

[00884] Pentatomidae (e.g., Scotinophara lurida, Malay black rice bug (Scotinophara coarctata), Nezara antennata, Eysarcoris aeneus, Eysarcoris lewisi, Eysarcoris ventralis, Eysarcoris annamita, Halyomorpha halys, Nezara viridula, Brown stink bug (Euschistus heros), Bedbug red-banded (Piezodorus guildinii), Oebalus pugnax, Dichelops melacanthus);

[00885] Cydnidae (e.g., brown rodent bug (Scaptocoris castanea));

[00886] Alydidae (for example, Riptortus pedestris, Leptocorisa chinensis or Leptocorisa acuta);

[00887] Coreidae (for example, Cletus punctiger or Leptoglossus australis);

[00888] Lygaeidae (e.g., Caverelius saccharivorus, Togo hemipterus or Blissus leucopterus);

[00889] Miridae (e.g., Trigonotylus caelestialium, Stenotus rubrovittatus, Stenodema calcarata or Lygus lineolaris);

[00890] Aleyrodidae (for example, Trialeurodes vaporariorum, Bemisia tabaci, Dialeurodes citri, Aleurocanthus spiniferus, Aleurocanthus camelliae or Pealius euryae);

[00891] Diaspididae (e.g., Abgrallaspis cyanophylli, Aonidella aurantii, Diaspidiotus perniciosus, Pseudaulacaspis pentagona, Unaspis yanonensis or Unaspis citri);

[00892] Coccidae (e.g., Ceroplastes rubens);

[00893] Margarodidae (e.g., Icerya purchasi or Icerya seychellarum);

[00894] Pseudococcidae (e.g., Phenacoccus solani, Phenacoccus solenopsis, Planococcus kraunhiae, Planococcus comstocki, Planococcus citri, Pseudococcus calceolariae, Pseudococcus longispinus or Brevennia rehi);

[00895] Psyllidae (e.g., Diaphorina citri, Trioza erytreae, Cacopsylla pyrisuga, Cacopsylla chinensis, Bactericera cockerelli or pear psylla (Cacopsylla pyricola));

[00896] Tingidae (e.g., Corythucha ciliata, Corythucha marmorata, Stephanitis nashi or Stephanitis pyrioides);

[00897] Cimicidae (e.g. Cimex lectularius); It is

[00898] Cicadidae (e.g. Giant Cicada (Quesada gigas)).

[00899] Lepidoptera

[00900] Crambidae (e.g., Chilo suppressalis, Dark-headed stem borer (Chilo polychrysus), White stem borer (Scirpophaga innotata), Scirpophaga incertulas, Rupela albina, Cnaphalocrocis medinalis, Marasmia patnalis, Marasmia exigua, Notarcha derogata, Ostrinia furnacalis, European corn borer (Ostrinia nubilalis), Hellula undalis, Herpetogramma luctuosale, Pediasia teterrellus, Nymphula depunctalis, Sugar cane borer (Diatraea saccharalis));

[00901] Pyralidae (e.g., Elasmopalpus lignosellus or Plodia interpunctella);

[00902] Noctuidae (e.g., Spodoptera litura, Spodoptera exigua, Mythimna separata, Mamestra brassicae, Sesamia inferens, Spodoptera mauritia, Naranga aenescens, Spodoptera frugiperda, Spodoptera exempta, Agrotis ipsilon, Autographa nigrisigna, Plusia festucae, Larva da soybean (Chrysodeixis includens), Trichoplusia spp., Heliothis spp. (e.g. Heliothis virescens), Helicoverpa armigera, Helicoverpa spp. (e.g. Helicoverpa zea), Soybean bollworm (Anticarsia gemmatalis), Cottonworm (Alabama argillacea), Hop borer (Hydraecia immanis)),

[00903] Pieridae (e.g., Pieris rapae);

[00904] Tortricidae (e.g., Grapholita molesta, Grapholita dimorpha, Leguminivora glycinivorella, Matsumuraeses azukivora, Adoxophyes orana fasciata, Adoxophyes honmai, Homona magnanima, Archips fuscocupreanus, Cydia pomonella, Tetramoera schistaceana, Bean sprout borer (Epinotia aporema) or Citrus fruit borer (Ecdytolopha aurantiana));

[00905] Gracillariidae (e.g., Caloptilia theivora or Phyllonorycter ringoniella);

[00906] Carposinidae (e.g., Carposina sasakii);

[00907] Lyonetiidae (for example, Coffee leaf miner (Leucoptera coffeela), Lyonetia clerkella or Lyonetia prunifoliella);

[00908] Lymantriidae (e.g., Lymantria spp. (e.g., Lymantria dispar) or Euproctis spp. (e.g., Euproctis pseudoconspersa));

[00909] Pluteliidae (e.g., Plutella xylostella);

[00910] Gelechiidae (e.g., Anarsia lineatella, Helcystogramma triannulellum, Pectinophora gossypiella, Phthorimaea operculella or Tuta absolut);

[00911] Arctiidae (e.g., Hyphantria cunea);

[00912] Castniidae (e.g. Giant Sugarcane borer (Telchin licus));

[00913] Cossidae (e.g., Cosus insularis);

[00914] Geometridae (e.g. Ascotis selenaria);

[00915] Limacodidae (e.g., Parasa lepida);

[00916] Stathmopodidae (e.g., Stathmopoda masinissa);

[00917] Sphingidae (e.g., Acherontia lachesis);

[00918] Sesiidae (e.g., Nokona feralis);

[00919] Hesperiidae (e.g., Parnara guttata).

[00920] Thysanoptera

[00921] Thripidae (e.g., Frankliniella occidentalis, Thrips palmi, Scirtothrips dorsalis, Thrips tabaci, Frankliniella intonsa, Stenchaetothrips biformis or Echinothrips americanus);

[00922] Phlaeothripidae (e.g., Haplothrips aculeatus).

[00923] Diptera

[00924] Anthomyiidae (for example, Delia platura or Delia antiqua);

[00925] Ulidiidae (e.g., Tetanops myopaeformis);

[00926] Agromyzidae (for example, Agromyza oryzae, Liriomyza sativae, Liriomyza trifolii or Chromatomyia horticola);

[00927] Chloropidae (e.g., Chlorops oryzae);

[00928] Tephritidae (for example, Bactrocera cucurbitae, Bactrocera dorsalis, Bactrocera latifrons, Bactrocera oleae, Bactrocera tryoni or Ceratitis capitata);

[00929] Ephydridae (e.g., Hydrellia griseola, Hydrellia philippina or Hydrellia sasakii);

[00930] Drosophilidae (e.g., Drosophila suzukii);

[00931] Phoridae (e.g., Megaselia spiracularis);

[00932] Psychodidae (e.g., Clogmia albipunctata);

[00933] Sciaridae (e.g., Bradysia difformis);

[00934] Cecidomyiidae (for example, Mayetiola destructor or Orseolia oryzae);

[00935] Diopsidae (e.g., Diopsis macrophthalma);

[00936] Tipulidae (e.g., Tipula aino, Common cranefly (Tipula oleracea) or European cranefly (Tipula paludosa)).

[00937] Coleoptera

[00938] Chrysomelidae (e.g., Diabrotica virgifera virgifera, Diabrotica undecimpunctata howardi, Diabrotica barberi, Diabrotica virgifera zeae, Diabrotica balteata, Curcubit beetle (Diabrotica speciosa), Cerotoma trifurcata, Oulema melanopus, Aulacophora femoralis, Phyllotreta striola okay, Cabbage flea beetle (Phyllotreta cruciferae), Western black flea beetle (Phyllotreta pusilla), Cabbage stem flea beetle (Psylliodes chrysocephala), Leptinotarsa decemlineata, Oulema oryzae, Colaspis brunnea, Chaetocnema pulicaria, Chaetocnema confinis, Epitrix cucumeris, Dicladispa armigera, Grape Colaspis (Colaspis brunnea), Southern corn flea beetle (Myochrous denticollis), Laccoptera quadrimacu or Epitrix hirtipennis);

[00939] Carabidae (e.g., corn beetle (Stenolophus lecontei) or fine corn beetle (Clivina impressifrons));

[00940] Scarabaeidae (e.g., Anomala cuprea, Anomala rufocuprea, Anomala albopilosa, Popillia japonica, Heptophylla picea, European Ladybug (Rhizotrogus majalis), Tomarus gibbosus, Holotrichia spp. or Phyllophaga spp. (e.g., Phyllophaga crinita )), Diloboderus spp. (e.g. Diloboderus abderus));

[00941] Curculionidae (Aracanthus spp. (e.g., Araecerus coffeae, Cylas formicarius, Euscepes postfasciatus, Hypera postica, Sitophilus zeamais, Echinocnemus squameus, Lissorhoptrus oryzophilus, Rhabdoscelus lineatocollis, Anthonomus grandis, Sphenophorus venatus, Southern corn ladybug ( Sphenophorus callosus), Soybean stem weevil (Sternechus subsignatus), Sugarcane weevil (Sphenophorus levis), Scepticus griseus, Scepticus uniformis, Zabrotes subfasciatus, Tomicus piniperda, Coffee borer (Hypothenemus hampei) or Aracanthus mourei) or Cotton root borer (Eutinobothrus brasiliensis);

[00942] Tenebrionidae (for example, Tribolium castaneum or Tribolium confusum);

[00943] Coccinellidae (e.g., Epilachna vigintioctopunctata);

[00944] Bostrychidae (e.g., Lyctus brunneus);

[00945] Ptinidae;

[00946] Cerambycidae (for example, Anoplophora malasiaca or Migdolus fryanus);

[00947] Elateridae (e.g., Melanotus okinawensis, Agriotes fuscicollis, Melanotus legatus, Anchastus spp., Conoderus spp., Ctenicera spp., Limonius spp., Aeolus spp.);

[00948] Staphylinidae (e.g., Paederus fuscipes).

[00949] Orthoptera

[00950] Acrididae (e.g., Locusta migratoria, Dociostaurus maroccanus, Chortoicetes terminifera, Nomadacris septemfasciata, Brown grasshopper (Locustana pardalina), Tree grasshopper (Anacridium melanorhodon), Italian grasshopper (Calliptamus italicus), Differential grasshopper (Melanoplus differentialis), Grasshopper Two-striped Grasshopper (Melanoplus bivittatus), Migratory Grasshopper (Melanoplus sanguinipes), Red-legged Grasshopper (Melanoplus femurrubrum), Light-winged Grasshopper (Camnula pellucida), Schistocerca gregaria, Yellow-winged Grasshopper (Gastrimargus musicus), Grasshopper spurge (Austracris guttulosa), Oxya yezoensis, Oxya japonica or Patanga succincta);

[00951] Gryllotalpidae (e.g., Gryllotalpa orientalis);

[00952] Gryllidae (e.g., Acheta domesticus or Teleogryllus emma);

[00953] Tettigoniidae (e.g., Mormon cricket (Anabrus simplex).

[00954] Hymenoptera

[00955] Tenthredinidae (for example, Athalia rosae or Athalia japonica);

[00956] Solenopsis spp.;

[00957] Formicidae (e.g., Brown Cut Ant (Atta capiguara)).

[00958] Blattodea

[00959] Blattellidae (e.g., Blattella germanica);

[00960] Blattidae (e.g., Periplaneta fuliginosa, Periplaneta americana, Periplaneta brunnea or Blatta orientalis);

[00961] Termitidae (e.g., Reticulitermes speratus, Coptotermes formosanus, Incisitermes minor, Cryptotermes domesticus, Odontotermes formosanus, Neotermes koshunensis, Glyptotermes satsumensis, Glyptotermes nakajimai, Glyptotermes fuscus, Hodotermopsis sjostedti, Coptotermes guangzhouensi s, Reticulitermes ama- mianus, Reticulitermes miyatakei, Reticulitermes kanmonensis, Nasutitermes takasagoensis, Pericapritermes nitobei, Sinocapritermes mushae or Cornitermes cumulans).

[00962] Acari

[00963] Tetranychidae (e.g., Tetranychus urticae, Tetranychus kanzawai, Tetranychus evansi, Panonychus citri, Panonychus ulmi or Oligonychus spp.);

[00964] Eriophyidae (e.g., Aculops pelekassi, Phyllocoptruta citri, Aculops lycopersici, Calacarus carinatus, Acaphylla theavagrans, Eriophyes chibaensis, Aculus schlechtendali, Aceria diospyri, Aceria tosichella or Shevtchenkella sp.);

[00965] Tarsonemidae (e.g., Polyphagotarsonemus latus);

[00966] Tenuipalpidae (for example, Brevipalpus phoenicis);

[00967] Tuckerellidae;

[00968] Ixodidae (e.g., Haemaphysalis longicornis, Haemaphysalis flava, Dermacentor taiwanensis, Dermacentor variabilis, Ixodes ovatus, Ixodes persulcatus, Ixodes scapularis, Amblyomma americanum, Boophilus microplus or Rhipicephalus sanguineus);

[00969] Acaridae (e.g., Tyrophagus putrescentiae or Tyrophagus similis);

[00970] Pyroglyphidae (e.g., Dermatophagoides farinae or Dermatophagoides pteronyssinus);

[00971] Cheyletidae (e.g., Cheyletus eruditus, Cheyletus malaccensis, Cheyletus moorei or Cheyletiella yasguri);

[00972] Sarcoptidae (for example, Otodectes cynotis or Sarcoptes scabiei);

[00973] Demodicidae (e.g., Demodex canis);

[00974] Listrophoridae;

[00975] Haplochthoniidae;

[00976] Macronyssidae (for example ounithonyssus bacoti or Ornithonyssus sylviarum);

[00977] Dermanyssidae (e.g., Dermanyssus gallinae);

[00978] Trombiculidae (e.g. Leptotrombidium akamushi).

[00979] The composition for controlling harmful arthropods of the present invention comprises the compound of the present invention and an inert active carrier. The composition for controlling harmful arthropods of the present invention is generally prepared by mixing the compound of the present invention with an inert active carrier such as solid carrier, liquid carrier or gaseous carrier and, if necessary, adding surfactants and other auxiliary agents. for formulation, to formulate into emulsifiable concentrates, oily solutions, powder formulations, granules, wettable powders, fluids, microcapsules, aerosols, fuming agents, poison baits, resin formulations, shampoo formulations, paste formulations, foams , carbon dioxide formulations and others. Such formulations can be processed into mosquito repellent coils, electric mosquito repellent mats, liquid mosquito formulations, fuming agents, fumigation materials, sheet formulations, direct application formulations or oral treatment formulations.

[00980] The composition for controlling harmful arthropods of the present invention generally comprises from 0.01 to 95% by weight of the compound of the present invention based on the total weights of the composition for controlling harmful arthropods.

[00981] Examples of the solid carrier to be used in the formulation include fine powders or granules of clays (for example, kaolin clay, diatomaceous earth, bentonite, Fubasami clay or acidic white clay), dry silica, wet silica, talcs, ceramics, other inorganic minerals (e.g. sericite, quartz, sulfur, active carbon or calcium carbonate) or chemical fertilizers (e.g. ammonium sulfate, ammonium phosphate, ammonium nitrate, urea or ammonium chloride) and others ; as well as synthetic resins (e.g., polyester resins such as polypropylene, polyacrylonitrile, polymethylmethacrylate and polyethylene terephthalate); nylon resins (e.g., nylon-6, nylon-11 and nylon-66); polyamide resins ; polyvinyl chloride, polyvinylidene chloride, vinyl chloride-propylene copolymers and others).

[00982] Examples of the aforementioned liquid vehicles include water; alcohols (for example, methanol, ethanol, isopropyl alcohol, butanol, hexanol, benzyl alcohol, ethylene glycol, propylene glycol or phenoxy ethanol); ketones (e.g. acetone, methyl ethyl ketone or cyclohexanone); aromatic hydrocarbons (e.g. toluene, xylene, ethyl benzene, dodecyl benzene, phenyl xylyl ethane or methylnaphthalene); aliphatic hydrocarbons (e.g. hexane, cyclohexane, kerosene or light oil); esters (e.g., ethyl acetate, butyl acetate, isopropyl myristate, ethyl oleate, diisopropyl adipate, diisobutyl adipate or propylene glycol monomethyl ether acetate); nitriles (e.g. acetonitrile or isobutyronitrile); ethers (e.g., diisopropyl ether, 1,4-dioxane, 1,2-dimethoxyethane, diethylene glycol dimethyl ether, diethylene glycol monomethyl ether, propylene glycol monomethyl ether, dipropylene glycol monomethyl ether, or 3-methoxy-3 -methyl- 1-butanol); amides (e.g. dimethylformamide (hereinafter referred to as DMF), dimethylacetamide); sulfoxides (e.g. DMSO); propylene carbonate; and vegetable oils (e.g. soybean oil or cottonseed oil).

[00983] Examples of the aforementioned gaseous vehicle include fluorocarbon, butane gas, liquefied petroleum gas (LPG), dimethyl ether and carbon dioxide gas.

[00984] Examples of surfactants include nonionic surfactants such as polyoxyethylenated alkyl ethers, polyoxyethylenated alkyl aryl ethers and polyethylene glycol fatty acid esters; and anionic surfactants such as alkyl sulfonates, alkylbenzene sulfonates and alkyl sulfates.

[00985] Examples of other auxiliary agents for formulation include a binder, a dispersant, a dye and a stabilizer. Specific examples include casein, gelatin, polysaccharides (e.g., starch, gum arabic, cellulose derivatives, and alginic acid), lignin derivatives, bentonite, water-soluble synthetic polymers (e.g., polyvinyl alcohol, polyvinyl pyrrolidone, and polyvinyl acids). - acrylics), acidic isopropyl phosphate, 2,6-di-tert-butyl-4-methylphenol and a mixture of 2-tert-butyl-4-methoxyphenol and 3-tert-butyl-4-methoxyphenol.

[00986] Examples of resin formulation base material include polyvinyl chloride, polyurethane and other polymers, and a plasticizer such as phthalate esters (e.g., dimethyl phthalate, dioctyl phthalate), acid esters Adipic and stearic acid can be added to these base materials if necessary. The resin formulation can be prepared by mixing the compound of the present invention with the above-mentioned base material, mixing the mixture with a customary mixer, followed by molding it through injection molding, extrusion molding or pressure molding, and so on. The resulting resin formulation may be subjected to another molding or cutting procedure and the like, if necessary, to be processed into forms such as plate, film, tape, net or wire form. These resin formulations can be processed into animal collars, animal ear tags, sheet products, trap ropes, gardening stands and other products.

[00987] Examples of a base material for poisonous baits include bait ingredients such as grain powder, vegetable oil, saccharide and crystalline cellulose and, if necessary, with the addition of antioxidants such as dibutylhydroxytoluene and nordihydroguaiaretic acid, preservatives such as dehydroacetic acid, accidental ingestion inhibitors for children and pets such as peppermint powder, and insect-attracting fragrances such as cheese flavor, onion flavor and peanut oil.

[00988] The method for controlling harmful arthropods of the present invention is conducted by applying an effective amount of the compound of the present invention to a harmful arthropod directly and/or its habitat (e.g., plant organisms, soil, an interior of a house, animal bodies). In the method for controlling harmful arthropods of the present invention, the present compound is generally used in the form of a harmful arthropod controlling composition.

[00989] When a composition for controlling harmful arthropods of the present invention is used for controlling harmful arthropods in an agricultural field, the application dose as an amount of the compound of the present invention is generally within a range of 1 to 10,000 g per 10,000 m2. When a composition for controlling harmful arthropods of the present invention is formulated into an emulsifiable concentrate, a wetting powder, or a circulable formulation, etc., the composition is generally applied by diluting with water such that a concentration of the compound of the present invention is within a range of 0.01 to 10,000 pm. The granular formulation, or starch formulation, etc., is generally applied as is without dilution.

[00990] These formulations or an aqueous dilution thereof can be distributed directly to harmful arthropods or plants (such as crops) to be protected from harmful arthropods, and can also be applied to the soil of cultivated land in order to control harmful arthropods in it. live.

[00991] Likewise, the resin preparation that is processed into a blade or a rope can be applied by wrapping a plant with a blade or a rope of the resin preparation, placing a rope of the resin preparation around of a crop so that the plant is surrounded by rope, or placing a slide of the resin preparation on the surface of the soil near the root of a plant.

[00992] When the harmful arthropod control composition of the present invention is used to control harmful arthropods living inside a house, the application dose as an amount of the present compound is generally within a range of 0.01 to 1000 mg per 1 m2 of an area to be treated, in case of using it on a flat area. In the case of its use in relation to space, the application dose as an amount of the present compound is generally within a range of 0.01 to 500 mg per 1 m3 of the space to be treated. When the harmful arthropod control composition of the present invention is formulated into emulsifiable concentrates, wetting powders, fluids or the like, such formulations are generally applied after dilution with water such that a concentration of the active ingredient is within a range of 0.1 to 10,000 ppm and then spraying. In case they are formulated in oily solutions, aerosols, fuming agents, poisonous baits and others, these formulations are used as they are without dilution.

[00993] When the composition for controlling harmful arthropods of the present invention is used to control external parasites of farm animals, such as cows, horses, pigs, sheep, goats and chickens and small animals such as dogs, cats, rats and mice, the composition of the present invention can be applied to animals by a method known in the veterinary field. Specifically, when systemic control is desired, the control composition of the present invention is administered to animals as a tablet, a mixture with feed or a suppository, or by injection (including intramuscular, subcutaneous, intravenous and intraperitoneal injections). . On the other hand, when non-systemic control is intended, the composition of the present invention is applied to animals by spraying the oily solution or aqueous solution, pouring treatment or by direct application or washing the animal with a shampoo formulation. , or by placing a collar or ear tag produced from the resin formulations on the animal. In the case of administration to an animal body, the dose of the present compound is generally within a range of 0.1 to 1000 mg per 1 kg of an animal's body weight.

EXAMPLES

[00994] Next, the present invention is explained in greater detail using the Preparation Example, the Formulation Example and the Test Example, however, the present invention should not be limited to these examples.

[00995] Firstly, the example of preparing the compound of the present invention is shown.

Reference Preparation Example 1

[00996] A mixture of 6-chloro-3-(ethanesulfonyl)-5-(trifluorophenyl)-5'-(2,2,3,3,3-pentafluoropropoxy)-2,2'-bipyirine 500 mg and water 28% ammonia 3 ml was stirred at 100°C for 5 hours. To the resulting mixture was added water at room temperature, and the mixture was extracted with ethyl acetate. The resulting organic layers were washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The resulting residue was subjected to a silica gel chromatographic column to obtain the intermediate compound (1) represented by the following formula 401 mg.

Intermediate compound (1)

[00997] 1H-NMR (CDCl3) d: 8.44 (1H, s), 8.35 (1H, s), 7.78 (1H, d), 7.39 (1H, d), 5.52 (2H, s), 4.53 (2H, t), 3.79 (2H, q), 1.37 (3H, t).

Reference Preparation Example 2 - 1

[00998] A mixture of 6-chloro-3-(ethanesulfonyl)-5'-(2,2,3,3,3-pentafluoropropoxy)-2,2'-bipyirine 600 mg, hydrazine monohydrate 219 mg, diethylisopropylamine 180 mg and THF 2 ml was stirred under reflux for 10 hours. To the resulting mixture was added water at room temperature, and the mixture was extracted with ethyl acetate. The resulting organic layers were washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The resulting residue was recrystallized from ethyl acetate and hexane to obtain intermediate compound (2) represented by the following formula 465 mg.

Intermediate compound (2)

[00999] 1H-NMR (CDCl3) d: 8.34 (1H, d), 8.17 (1H, d), 7.70 (1H, d), 7.37 (1H, dd), 6.89 (1H, d), 6.40 (1H, s), 4.52 (2H, t), 3.93 (2H, s), 3.66 (2H, q), 1.32 (3H, t) .

Reference Preparation Example 2 - 2

[001000] The compound that was prepared according to the method described in Reference Preparation Example 2-1, and its physical property values are shown below.

Intermediate compound (3)

[001001] 1H-NMR (CDCl3) d: 8.40 (1H, s), 8.37 (1H, d), 7.82 (1H, d), 7.41 (1H, dd), 6.74 (1H, s), 4.55 (2H, t), 4.19 (2H, d), 3.80 (2H, q), 1.37 (3H, t).

Preparation Example 1

[001002] A mixture of intermediate compound (2) 185 mg, 1,1'-carbonyldiimidazole 81 mg and NMP 2 ml was stirred at room temperature for 2 hours. To the resulting mixture was added water at room temperature, and the mixture was extracted with ethyl acetate. The resulting organic layers were washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The resulting residue was subjected to a silica gel chromatographic column to obtain the present compound 1 represented by the following formula 171 mg.

Compound Gift 1

[001003] 1H-NMR (CDCl3) d: 10.17 (1H, s), 8.38 (1H, d), 7.59 (1H, d), 7.56 (1H, d), 7.36 (1H, dd), 7.22 (1H, d), 4.55 (2H, t), 3.15 (2H, q), 1.28 (3H, t).

Preparation Example 2

[001004] The compound that was prepared according to the method described in Preparation Example 1, and its physical property values are shown below.

Compound Gift 2

[001005] 1H-NMR (CDCl3) d: 10.59 (1H, s), 8.40 (1H, d), 7.95 (1H, s), 7.57 (1H, d), 7.38 (1H, dd), 4.57 (2H, t), 3.22-3.17 (2H, m), 1.29 (3H, t).

Preparation Example 3

[001006] A mixture of intermediate compound (3) 247 mg, trimethyl orthoformate 5 ml and trifluoroacetic acid 57 µl was stirred at 110 °C for 3 hours. To the resulting mixture, water was added at room temperature, and the mixture was extracted with ethyl acetate. The resulting organic layers were washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The resulting residue was subjected to a silica gel chromatographic column (hexane : ethyl acetate = 1 : 1) to obtain the present compound 3 represented by the following formula 249 mg.

Compound Gift 3

[001007] 1H-NMR (CDCl3) d: 8.59 (1H, dd), 8.49 (1H, s), 8.26 (1H, d), 7.76 (1H, dd), 7.56 (1H, dd), 4.63 (2H, t), 3.23 (2H, q), 1.31 (3H, t).

Preparation Example 4

[001008] The compound that was prepared according to the method described in Preparation Example 3, and its physical property values are shown below.

Composite gift 4

[001009] 1H-NMR (CDCl3) d: 8.57 (1H, dd), 8.39 (1H, d), 7.98 (1H, dd), 7.90 (1H, d), 7.73 (1H, dd), 7.54 (1H, dd), 4.62 (2H, td), 3.19 (2H, q), 1.28 (3H, t).

Preparation Example 5

[001010] A mixture of intermediate compound (1) 300 mg, 2-chloroethylamine hydrochloride salt 105 mg, diethylisopropylamine 310 µl and NMP 2 ml was stirred at 120 °C for 7 hours. To the resulting mixture was added water at room temperature, and the mixture was extracted with ethyl acetate. The resulting organic layers were washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The resulting residue was subjected to a silica gel chromatographic column (hexane : ethyl acetate = 1 : 1) to obtain the present compound 5 represented by the following formula 138 mg.

Composite gift 5

[001011] 1H-NMR (CDCl3) d: 8.43 (1H, d), 7.74 (1H, d), 7.53 (1H, d), 7.41 (1H, dd), 4.54 (2H, t), 4.08-4.03 (2H, m), 3.61 (2H, d), 2.93 (2H, q), 1.25 (3H, t).

Preparation Example 6

[001012] A mixture of intermediate compound (1) 300 mg, 2-chloroacetaldehyde 1.05 g, and NMP 2 ml was stirred at 120 ° C for 7 hours. To the resulting mixture was added water at room temperature, and the mixture was extracted with ethyl acetate. The resulting organic layers were washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The resulting residue was subjected to a silica gel chromatographic column (hexane : ethyl acetate = 2 : 1) to obtain the present compound 6 represented by the following formula 200 mg.

Composite gift 6

[001013] 1H-NMR (CDCl3) d: 8.56 (1H, d), 8.20 (1H, s), 7.84 (1H, d), 7.67 (1H, d), 7.53 (1H, dd), 7.20 (1H, d), 4.61 (2H, t), 3.25-3.21 (2H, m), 1.29 (3H, t).

[001014] Next, formulation examples of the Present compound are shown below. "Parts" represent "part by weight" unless otherwise specified.

Formulation Example 1

[001015] In a mixture of 35 parts of xylene and 35 parts of DMF, 10 parts of any of the present compounds 1 to 6 are dissolved, and then 14 parts of polyoxyethylene styryl phenyl ether and 6 parts of polyoxyethylene dodecylbenzene sulfonate calcium are added, followed by mixing to obtain each formulation.

Formulation Example 2

[001016] Four (4) parts of sodium lauryl sulfate, 2 parts of calcium lignin sulfonate, 20 parts of synthetic hydrated silicon fine powder and 54 parts of diatomaceous earth are mixed, plus 20 parts of any of the present compounds 1 to 6 are added, followed by their mixing to obtain each humectant powder.

Formulation Example 3

[001017] To 2 parts of any of the present compounds from 1 to 6, 1 part of fine synthetic hydrated silicon oxide powder, 2 parts of calcium lignin sulfonate, 30 parts of bentonite and 65 parts of kaolin clay are added, followed by mixing, granulation with a granulator and drying with air under pressure to obtain each granular formulation.

Formulation Example 4

[001018] In an appropriate amount of acetone, 1 part of any of the present compounds 1 to 6 is mixed, and then 5 parts of fine synthetic hydrated silicon oxide powder, 0.3 parts of isopropyl acid phosphate and 93 7 parts of kaolin clay are added, followed by mixing with careful stirring and removing acetone from the mixture through evaporation to obtain each powder formulation.

Formulation Example 5

[001019] A mixture of 35 parts of polyoxyethylene alkyl ether ammonium sulfate salt and white carbon (weight ratio 1:1), 20 parts of any of the present compounds 1 to 6, and 45 parts of water are mixed, followed by fine grinding through a wet grinding method to obtain each circulatable formulation.

Formulation Example 6

[001020] In a mixture of 5 parts of xylene and 5 parts of trichloroethane, 0.1 part of any of the present compounds 1 to 6 is dissolved, and the resulting mixture is then mixed with 89.9 parts of kerosene to obtain each oil solution.

Formulation Example 7

[001021] In 0.5 ml of acetone, 10 mg of any of the present compounds 1 to 6 are dissolved and the solution is added dropwise to 5 g of a solid feed powder for an animal (solid feed powder for an animal). cultivation and breeding CE-2, manufactured by CLEA Japan, Inc.), followed by mixing the resulting mixture evenly, and then drying it by acetone evaporation to obtain each poisonous bait.

Formulation Example 8

[001022] In an aerosol can, 0.1 part of any of the present compounds from 1 to 6 and 49.9 parts of Neothiozole (Chuo Ka-sei Co., Ltd.) are placed. After assembling an aerosol valve, 25 parts of dimethyl ether and 25 parts of LPG are charged, followed by shaking and another assembly of an actuator to obtain an oily aerosol.

Formulation Example 9

[001023] A mixture of 0.6 part of any of the present compounds from 1 to 6, 0.01 part of BHT (2,6-di-tert-butyl-4-methylphenol), 5 parts of xylene, 3, 39 parts of deodorized kerosene and 1 part of an emulsifier {Rheodol MO-60 (registered trademark of Kao Corporation)} and 50 parts of distilled water are loaded into an aerosol container, and a part of the valve is turned on. Then, 40 parts of a propellant (LPG) are charged through the valve under pressure to obtain an aqueous aerosol.

Formulation Example 10

[001024] Zero point one (0.1) part of any of the present compounds from 1 to 6 is mixed in 2 ml of propylene glycol, and the resulting solution is impregnated into a ceramic plate having a size of 4.0 cm x 4.0 cm and a thickness of 1.2 cm, to obtain thermal materials for fumigation.

Formulation Example 11

[001025] Five (5) parts of any one of Gifts composed of 1 to 6, and 95 parts of ethylene-methyl methacrylate copolymer (the ratio of methyl methacrylate in the copolymer: 10% by weight), Acryft (registered trademark ) WD 301, manufactured by Sumitomo Chemical Co. Ltd.) are melted and mixed with a closed-type pressure mixer (manufactured by Moriyama Manufacturing Co. Ltd.), and the resulting mixed product is extruded from a molding machine by extrusion through a molding die to obtain a rod-shaped molded product having a length of 15 cm and a diameter of 3 mm.

Formulation Example 12

[001026] Five (5) parts of any one of Gifts composed of 1 to 6, and 95 parts of plasticized polyvinyl chloride resin are melted and mixed with a closed-type pressure mixer (manufactured by Moriyama Manufacturing Co. Ltd.), and the resulting mixed product is extruded from an extrusion molding machine through a molding die to obtain a rod-shaped molded product having a length of 15 cm and a diameter of 3 mm.

Formulation Example 13

[001027] One hundred (100) mg of any of the Present compounds 1 to 6, 68.75 mg of lactose, 237.5 mg of corn starch, 43.75 mg of microcrystalline cellulose, 18.75 mg of polyvinylpyrrolidone, 28.75 mg of sodium carbomethyl starch and 2.5 mg of magnesium stearate are mixed, and the resulting mixture is compressed into an appropriate size to obtain a tablet.

Formulation Example 14

[001028] Twenty five (25) mg of any of the present compounds from 1 to 6, 60 mg of lactose, 25 mg of corn starch, 6 mg of carmellose calcium and an appropriate amount of 5% hydroxypropyl methylcellulose are mixed, and the resulting mixture is loaded into a rigid gelatin capsule or a hydroxypropyl methylcellulose capsule to obtain capsules. Formulation Example 15

[001029] At 100 mg of any of the present compounds from 1 to 6, 500 mg of fumaric acid, 2000 mg of sodium chloride, 150 mg of methyl paraben, 50 mg of propyl paraben, 25000 mg of granulated sugar, 13,000 mg of sorbitol (70% solution), 100 mg of Veegum K (manufactured by Vanderbilt Co.), 35 mg of perfume and 500 mg of coloring agent, distilled water is added so that a final volume is set to be 100 ml, followed by mixing to obtain a suspension for oral administration.

Formulation Example 16

[001030] In a mixture of 5% by weight of an emulsifier, 3% by weight of benzyl alcohol and 30% by weight of propylene glycol, 5% by weight of any of the present compounds 1 to 6 are dissolved, and buffer of phosphate is added so that a pH of the solution is set to be 6.0 to 6.5, and water is added as the remaining parts to obtain the solution for oral administration.

Formulation Example 17

[001031] To a mixture of 57% by weight of fractional distilled palm oil and 3% by weight of polysorbate 85, 5% by weight of aluminum distearate are added, and heated for its dispersion. The resulting mixture is cooled to room temperature, and 25% by weight of saccharin is dispersed in an oily vehicle. 10% by weight of any of the present compounds 1 to 6 are divided to obtain a paste for oral administration.

Formulation Example 18

[001032] Five (5) % by weight of any of the present compounds from 1 to 6 are mixed with 95% by weight of limestone filler, followed by wet granulation of the resulting mixture to obtain a granule for oral administration.

Formulation Example 19

[001033] In 80 parts of diethylene glycol monomethyl ether, 5 parts of any of the present compounds 1 to 6 are dissolved, and 15 parts of propylene carbonate are added, and the resulting mixture is mixed to obtain a solution of direct application.

Formulation Example 20

[001034] In 70 parts of diethylene glycol monomethyl ether, 10 parts of any of the present compounds 1 to 6 are dissolved, and 20 parts of 2-octyldodecanol are added, and the resulting mixture is mixed to obtain an application solution direct.

Formulation Example 21

[001035] To 0.5 part of any of the present compounds from 1 to 6, 60 parts of Nikkol (registered trademark) TEALS-42 (manufactured by Nikko Chemical Co. Ltd.: 42% aqueous acid triethanol amine solution sulfuric lauryl) and 20 parts of propylene glycol are added, and the resulting mixture is mixed with careful stirring, and 19.5 parts of water are then added and the resulting mixture is further mixed with careful stirring to obtain a hydrogenous solution of shampoo formulation.

Formulation Example 22

[001036] Zero point 15 (0.15)% by weight of any of the present compounds from 1 to 6, 95% by weight of animal feed, as well as 4.85% by weight of a mixture of dibasic calcium phosphate, diatomaceous earth, aerosol and carbonate (or chalk) are mixed with careful stirring to obtain a premix for animal feed.

Formulation Example 23

[001037] Seven point two (7.2) g of any of the present compounds 1 to 6, and 92.8 g of Hosco (registered trademark) S-55 (manufactured by Maruishi Pharmaceuticals) are melted and mixed with 100 °C, and the resulting mixture was poured into a suppository mold, followed by performing a cooling solidification to obtain a suppository.

[001038] In the following, Test Examples are used to show the effectiveness of the present compound in controlling harmful arthropods.

[001039] The following Test Examples were carried out at 25 °C.

Test Example 1

[001040] Test compounds were produced into a formulation according to the method described in Formulation Example 5, and in addition water containing 0.03% v/v was added from a dispenser to prepare a diluted solution containing a prescribed concentration of the test compound.

[001041] Cucumber seedling (Cucumis sativus) (in the stage of development of the second authentic leaf) was planted in a container and approximately 30 cotton aphids (Aphis gossypii) (all life stages) were released onto the leaves of the cucumber. After 1 day, the diluted solutions were sprayed on the seedling at a rate of 10 ml/seedling. After 5 days, the number of surviving insects was examined and the control value was calculated by the following equation. Control value (%) = {1-(CbxTai)/(CaixTb)}x100 where the symbols in the formula represent the following descriptions.

[001042] Cb: Number of test insects in the untreated group;

[001043] Cai: Number of surviving insects at the time of investigation in the untreated group;

[001044] Tb: Number of test insects in the treated group;

[001045] Tai: Number of surviving insects at the time of investigation in the treated group;

[001046] Here the "untreated group" represents a group where a treatment procedure similar to that of the treated group except not using the test compound is carried out.

[001047] The test was conducted by preparing the prescribed concentration 500 ppm and using the present compounds mentioned below as a test compound according to Test Example 1. As a result of the test, the present compounds mentioned below showed 90% or more as the control value. Composite gifts: 1,2, 3, 4, 5, and 6

[001048] The test was conducted by preparing the prescribed concentration 200 ppm and using the present compounds mentioned below as a test compound according to Test Example 1. As a result of the test, the present compounds mentioned below showed 90% or more as the control value. Composite gifts: 1,2, 3, 4, 5 and 6

Test Example 2

[001049] Test compounds were prepared for a formulation according to the method described in Formulation Example 5, and in addition water was added to prepare a dilute solution containing a prescribed concentration of the test compound.

[001050] Cucumber seedling (at the stage of development of the second authentic leaf) was planted in a container, and the solutions diluted at a ratio of 5 ml/seedling were irrigated at the base of the plant. After 7 days, approximately 30 cotton aphids (all life stages) were inoculated onto cucumber leaves. After an additional 6 days, the number of surviving insects was examined, and the control value was calculated by the following equation. Control value (%) = {1-(CbxTai)/(CaixTb)}x100 where the symbols in the formula represent the following descriptions.

[001051] Cb: Number of test insects in the untreated group;

[001052] Cai: Number of surviving insects at the time of investigation in the untreated group;

[001053] Tb: Number of test insects in the treated group;

[001054] Tai: Number of surviving insects at the time of investigation in the treated group;

[001055] Here the "untreated group" represents a group where a treatment procedure similar to that of the treated group except not using the test compound is carried out.

[001056] The test was conducted by preparing the prescribed concentration 1000 ppm and using the present compounds mentioned below as a test compound according to Test Example 2. As a result of the test, the present compound mentioned below showed 90% or more as the control value.

Composite gift: 4 Test Example 3

[001057] Test compounds were prepared for a formulation according to the method described in Formulation Example 5, and in addition water containing 0.03% v/v was added from a dispenser to prepare a diluted solution containing a prescribed concentration of the test compound.

[001058] Rice seedling (Oryza sativa) (at the stage of development of the second authentic leaf) was planted in a container, and the diluted solutions were sprayed on the seedling at a rate of 10 ml/seedling. After that, 20 of the 3rd larval stage larvae of brown locust (Nilaparvata lugens) were released onto the rice leaves. After 6 days, the number of surviving insects was examined, and mortality was calculated by the following equation. Mortality (%) = {1- the number of surviving insects/20} x 100

[001059] The test was conducted by preparing the prescribed concentration 500 ppm and using the present compounds mentioned below as a test compound according to Test Example 3. As a result of the test, the present compound mentioned below showed 90% or more as the control value.

Present compound: 4 Test Example 4

[001060] Test compounds were prepared for a formulation according to the method described in Formulation Example 5, and in addition water was added to prepare a dilute solution containing a prescribed concentration of the test compound.

[001061] Rice seedling (Oryza sativa) (at the stage of development of the second authentic leaf) was planted in a container, and the diluted solutions were sprayed on the seedling at a rate of 10 ml/seedling. The diluted solution was added to the container, and in the container, the rice seedling (in the stage of development of the second authentic leaf) that was planted in a container with a hole on its lower side was accommodated. After 7 days, 20 of the larvae in the 3rd larval stage of brown locust (Nilaparvata lugens) were released onto the rice leaves. After 6 days, the number of surviving insects was examined, and mortality was calculated by the following equation. Mortality (%) = {1- the number of surviving insects/20} x 100

Test Example 5

[001062] Test compounds were prepared for a formulation according to the method described in Formulation Example 5, and in addition water was added to prepare a dilute solution containing a prescribed concentration of the test compound.

[001063] In a container, 7.7 g of artificial diet (Insecta LF, manufactured by NOSAN CORPORATION) were placed, and 2 ml of the diluted solution were irrigated. Five (5) larvae of the fourth larval stage of tobacco yellowtail woodworm (Spodoptera litura) were released into the artificial diet. After 5 days, the number of surviving insects was examined, and insect mortality was calculated by the following equation. Mortality (%) = {1- the number of surviving insects/5} x 100

[001064] The test was conducted by preparing the prescribed concentration 500 ppm and using the present compounds mentioned below as a test compound according to Test Example 5. As a result of the test, the present compounds mentioned below showed 80% or more in terms of mortality.

Composite gifts: 3 and 6 Test Example 6

[001065] Test compounds were produced into a formulation according to the method described in Formulation Example 5, and in addition water containing 0.03% v/v was added from a dispenser to prepare a diluted solution containing a prescribed concentration of the test compound.

[001066] The diluted solutions were sprayed on the cabbage seedling (Brassicae oleracea) (in the development stage of the second to third authentic leaves) which was planted in a container at a ratio of 20 ml/seedling. After that, the stem and leaf were cut and were then installed in the container which was covered with the filter paper. Five (5) cabbage moths (Plutella xilostella) in the second larval instar stages were released into the cup. After 5 days, the number of surviving insects was counted, and insect mortality was calculated by the following equation. Mortality (%) = {1- the number of surviving insects/5} x 100

[001067] The test was conducted by preparing the prescribed concentration 500 ppm and using the present compounds mentioned below as a test compound according to Test Example 5. As a result of the test, the present compounds mentioned below showed 80% or more in terms of mortality. Compound Presents: 1,4 and 6 Test Example 7

[001068] Test compounds were produced into a formulation according to the method described in Formulation Example 5, and in addition water containing 0.03% v/v was added from a dispenser to prepare a diluted solution containing a prescribed concentration of the test compound.

[001069] The diluted solutions were sprayed on the cabbage seedling (in the development stage of the third to fourth authentic leaf) which was planted in a container at a ratio of 20 ml/seedling. Thereafter, ten (10) cabbage moths (Plutella xilostella) in the larval stages of the third larval stage were released into the cup. After 5 days, the number of surviving insects was counted, and insect mortality was calculated by the following equation. Mortality (%) = {1- the number of surviving insects/10} x 100

[001070] The test was conducted by preparing the prescribed concentration 200 ppm and using the present compounds mentioned below as a test compound according to Test Example 7. As a result of the test, the present compounds mentioned below showed 90% or more in terms of mortality.

Composite gifts: 2, 3, 5 and 6 Test Example 8

[001071] The test compounds were dissolved in a mixed solution of polyoxyethylene sorbitan mono-cocoate and acetone (acetone and polyoxyethylene sorbitan mono-cocoate = 5 : 95 (v/v ratio)) in a ratio of 50 µl of the solution mixed with 1 mg of the test compound. To this was added water containing 0.03% by volume from a dispenser to prepare a dilute solution containing a prescribed concentration of the test compound.

[001072] Corn (Zea mays) was sown in a tray covered with moistened KimWipes (Trademark). After the corns had been grown for 5 days, the entire corn seedling was immersed in the diluted solution for 30 seconds. Thereafter, every two kernels of the seedling were installed in a plastic Petri dish (radius 90 mm), and 10 western corn rootworms (Diabrotica virgifera virgifera) in the second instar larval stages were released into the cup. . After 5 days, the number of dead insects was counted, and insect mortality was calculated by the following equation. Mortality (%) = {1- the number of surviving insects/10} x 100

[001073] The test was conducted by preparing the prescribed concentration 500 ppm and using the present compounds mentioned below as a test compound according to Test Example 8. As a result of the test, the present compounds mentioned below showed 80% or more in terms of mortality.

Composite gifts: 1,3, 4, 5 and 6 Industrial Applicability

[001074] The present compound shows an excellent control effect against a harmful arthropod.

Claims (15)

1. Compound, characterized by the fact that it is represented by formula (I): wherein Q represents a group represented by the following formula Q1, a group represented by the following formula Q2, a group represented by the following formula Q3, or a group represented by the following formula Q4: wherein n is 0, 1 or 2, R2 represents a cyclopropyl group, a cyclopropylmethyl group, or a C1-C6 alkyl group optionally having one or more halogen atoms, Z1 represents a nitrogen atom or CR3c, Z2 represents a nitrogen atom nitrogen or CR3d, Z3 represents a nitrogen atom or CR3e, Z4 represents NR34, CR36R37 or C(O), Z5 represents NR35, CR38R39 or C(O), R3a, R3b, R3c, R3d and R3e each independently represents a group of C1-C6 chain hydrocarbon optionally having one or more substituents selected from Group B, OR12, NR11R12, NR29NR11R12, NR29OR11, NR11C(O)R13, NR29NR11C(O)R13, NR11C(O)OR14, NR29NR11C(O)OR14, NR11C(O)NR15R16, NR29NR11C(O)NR15R16, N=CHNR15R16, N=S(O)xR15R16, C(O)OR17, a cyano group, a nitro group, a halogen atom, or a hydrogen atom, x is 0 or 1, R34 and R35 each independently represent a C1-C6 chain hydrocarbon group optionally having one or more substituents selected from Group B, a C3-C7 aliphatic hydrocarbon group optionally having one or more substituents selected from Group C , C(O)ORd, C(O)Rd, C(O)NReRf, S(O)2Ri, or a hydrogen atom, R36, R37, R38 and R39 each independently represent a C1- chain hydrocarbon group C6 optionally having one or more substituents selected from Group B, a C3-C7 aliphatic hydrocarbon group optionally having one or more substituents selected from Group C, or a hydrogen atom, Rd represents a C1 chain C6 hydrocarbon group optionally having a or more halogen atoms, or a hydrogen atom, Re and Rf each independently represent a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, a C3-C7 aliphatic hydrocarbon group optionally having one or more halogen atoms, or a hydrogen atom, Ri represents a hydrocarbon group of chain C1-C6 optionally having one or more halogen atoms), A2 represents a nitrogen atom or CR4a, A3 represents a nitrogen atom or CR4b, A4 represents a nitrogen atom or CR4c, R4a, R4b, and R4c each independently represents a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, a nitro group, OR18, NR18R19, a cyano group, a of halogen or a hydrogen atom, R18 represents a C1C6 chain hydrocarbon group optionally having one or more halogen atoms, R19 represents a C1C6 chain hydrocarbon group optionally having one or more halogen atoms or a hydrogen atom, T represents a C1C10 chain hydrocarbon group having one or more halogen atoms, a (C1-C5 alkoxy) C2-C5 alkyl group having one or more halogen atoms, a (C1C5 alkylsulfanyl) C2-C5 alkyl group having one or more halogen atoms, a (C1-C5 alkylsulfinyl) C2-C5 alkyl group having one or more halogen atoms, a (C1-C5 alkylsulfonyl) C2-C5 alkyl group having one or more halogen atoms, OR1, S(O) mR1, OS(O)2R1, CH2OR1, NR1R24, C(O)R1, C(O)NR1R24, NR24C(O)R1, or N=CR1R30, m is 0, 1, or 2, R1 represents a hydrocarbon group chain C1C10 having one or more halogen atoms, a (C1-C5 alkoxy) C2-C5 alkyl group having one or more halogen atoms, a (C1C5 alkylsulfanyl) C2-C5 alkyl group having one or more halogen atoms, a (C1-C5 alkylsulfinyl) C2-C5 alkyl group having one or more halogen atoms, a (C1-C5 alkylsulfonyl) C2-C5 alkyl group having one or more halogen atoms, a (C3-C7 cycloalkyl) C1-C3 group alkyl having one or more substituents selected from Group G, or a C3-C7 cycloalkyl group having one or more substituents selected from Group G, R11, R17, R24 and R29 each independently represents a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, or a hydrogen atom, R30 represents a C1C6 chain hydrocarbon group optionally having one or more halogen atoms, or a hydrogen atom, R12 represents a C1C6 chain hydrocarbon group optionally having one or more halogen atoms, a C1-C6 alkyl group having a substituent selected from Group F, S(O)2R23, or a hydrogen atom, R23 represents a C1C6 chain hydrocarbon group optionally having one or more halogen atoms, or a phenyl group optionally having one or more substituents selected from Group D, R13 represents a C1C6 chain hydrocarbon group optionally having one or more halogen atoms, a (C3-C6 cycloalkyl) C1-C3 alkyl group optionally having one or more atoms of halogen, or a hydrogen atom, R14 represents a C1C6 chain hydrocarbon group optionally having one or more halogen atoms, or a C1-C3 alkyl (C3-C6 cycloalkyl) group optionally having one or more halogen atoms, R15 and R16 each independently represents a C1-C6 alkyl group optionally having one or more halogen atoms, Group B: a group consisting of a cyano group, a hydroxy group, and a halogen atom; C group: a group consisting of a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, a C1-C6 alkoxy group optionally having one or more halogen atoms, a C3-C6 alkenyloxy group optionally having a or more halogen atoms, a C3C6 alkynyloxy group optionally having one or more halogen atoms, and a halogen atom; Group D: a group consisting of a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, a hydroxy group, a C1-C6 alkoxy group optionally having one or more halogen atoms, a C3C6 alkenyloxy group optionally having one or more halogen atoms, a C3-C6 alkynyloxy group optionally having one or more halogen atoms, a sulfanyl group, a C1-C6 alkylsulfanyl group optionally having one or more halogen atoms, a C1C6 alkylsulfinyl group optionally having one or more more halogen atoms, a C1-C6 alkylsulfonyl group optionally having one or more halogen atoms, an amino group, NHR21, NR21R22, C(O)R21, OC(O)R21, C(O)OR21, a cyano group, a nitro group, and a halogen atom {R21 and R22 each independently represent a C1-C6 alkyl group optionally having one or more halogen atoms}; Group F: a group consisting of a C1-C6 alkoxy group optionally having one or more halogen atoms, a phenyl group optionally having one or more substituents selected from Group D, a five- to six-membered aromatic heterocyclic group optionally having one or plus substituents selected from Group D, a C3-C7 cycloalkyl group optionally having one or more halogen atoms, a three- to seven-membered non-aromatic heterocyclic group optionally having one or more substituents selected from Group C, an amino group, NHR21, NR21R22 , and a cyan group; Group G: a group consisting of a C1-C6 alkyl group having one or more halogen atoms. 2. Compound according to claim 1, characterized by the fact that R4a, R4b and R4c each independently represent a hydrogen atom, or a halogen atom, T represents OR1, R1 represents a C1-C5 chain hydrocarbon group having one or more halogen atoms, R2 represents a C1-C6 alkyl group, Q represents a group represented by the above formula Q1 or a group represented by the above formula Q2, R3a and R3b each independently represents a C1-C6 alkyl group optionally having one or more halogen atoms, OR12, NR11R12, NR11C(O)R14, a halogen atom or a hydrogen atom, R3c, R3d and R3e each independently represents a C1-C6 alkyl group optionally having one or more halogen atoms , OR12, a halogen atom or a hydrogen atom, Z4 represents CR36R37 or C(O), Z5 represents NR35 or CR38R39, R35 represents a C1-C6 alkyl group or a hydrogen atom, and R36 and R37 each independently represent a C1-C6 alkyl group optionally having one or more halogen atoms, or a hydrogen atom, and R37 and R38 each represent a hydrogen atom. 3. Compound according to claim 2, characterized in that R1 represents a C1-C5 alkyl group having three or more fluorine atoms, R3a and R3b each independently represent a C1-C6 alkyl group optionally having one or more atoms of halogen, OR12, a halogen atom, or a hydrogen atom, and R4a, R4b, and R4c each represent a hydrogen atom. 4. Compound according to claim 3, characterized by the fact that R2 represents an ethyl group, and R3c, R3d, R3e, R35, R36, R37, R38 and R39 each represent a hydrogen atom. 5. Compound according to any one of claims 1 to 4, characterized in that A2 represents CR4a and A4 represents CR4c. 6. Compound according to any one of claims 1 to 4, characterized in that A2 represents CR4a, A3 represents CR4b and A4 represents CR4c. 7. Compound according to claim 1, characterized in that A2 represents CR4a, A3 represents CR4b, A4 represents CR4c, R4a, R4b and R4c each independently represent a hydrogen atom or a halogen atom, T represents OR1, R1 represents a C1-C5 chain hydrocarbon group having one or more halogen atoms, R2 represents a C1-C6 alkyl group, Q represents a group represented by the above formula Q1, R3a and R3b each independently represents a C1-C6 group alkyl optionally having one or more halogen atoms, OR12, NR11R12, NR11C(O)OR14, a halogen atom or a hydrogen atom, and R3c, R3d and R3e each independently represents a C1-C6 alkyl group optionally having one or plus halogen atoms, OR12, a halogen atom or a hydrogen atom. 8. Compound according to claim 7, characterized in that R1 represents a C1-C5 alkyl group having three or more fluorine atoms, R3a and R3b each independently represent a C1-C6 alkyl group optionally having one or more atoms of halogen, OR12, a halogen atom, or a hydrogen atom, and R4a, R4b, and R4c each represent a hydrogen atom. 9. Compound according to claim 7 or 8, characterized by the fact that R3c, R3d and R3e each represent a hydrogen atom. 10. Compound according to claim 1, characterized by the fact that A2 represents CR4a, A3 represents CR4b, A4 represents CR4c, R4a, R4b and R4c each independently represent a hydrogen atom or a halogen atom, T represents OR1, R1 represents a C1-C5 chain hydrocarbon group having one or more halogen atoms, R2 represents a C1-C6 alkyl group, Q represents a group represented by the above formula Q2, R3a and R3b each independently represents a C1 group -C6 alkyl optionally having one or more halogen atoms, OR12, NR11R12, NR11C(O)OR14, a halogen atom or a hydrogen atom, Z4 represents CR36R37 or C(O), Z5 represents NR35 or CR38R39, R3e represents a C1-C6 alkyl group optionally having one or more halogen atoms, OR12, a halogen atom or a hydrogen atom, R35 represents a C1-C6 alkyl group or a hydrogen atom, R36 and R38 each independently represents a C1 group -C6 alkyl optionally having one or more halogen atoms, or a hydrogen atom, and R37 and R38 each represent a hydrogen atom. 11. Compound according to claim 10, characterized in that R1 represents a C1-C5 alkyl group having three or more fluorine atoms, R3a and R3b each independently represent a C1-C6 alkyl group optionally having one or more atoms of halogen, OR12, a halogen atom, or a hydrogen atom, and R4a, R4b, and R4c each represent a hydrogen atom. 12. Compound according to claim 10 or 11, characterized in that R2 represents an ethyl group, and R35, R36, R37, R38 and R39 each represent a hydrogen atom. 13. Composition for controlling a harmful arthropod, characterized by the fact that it comprises the compound as defined in any one of claims 1 to 12 and an inert carrier. 14. Composition for controlling a harmful arthropod according to claim 13, characterized by the fact that it comprises one or more ingredients selected from the group consisting of the following Group (a), Group (b), Group (c), Group (d) and Group (e), and the compound as defined in any one of claims 1 to 12, Group (a): a group consisting of insecticidal ingredients, miticide ingredients and nematicide ingredients; Group (b): fungicidal ingredients; Group (c): ingredients that modulate plant growth; Group (d): phytotoxicity-reducing ingredients; and Group (e): synergistic ingredients. 15. Non-therapeutic method for controlling a harmful arthropod, characterized by the fact that it comprises applying an effective amount of the compound as defined in any one of claims 1 to 12 to a harmful arthropod or a habitat where a harmful arthropod lives.