BR112018016725A2 - pharmaceutical composition to prevent and treat sleep disorders - Google Patents

pharmaceutical composition to prevent and treat sleep disorders

Info

Publication number
BR112018016725A2
BR112018016725A2 BR112018016725A BR112018016725A BR112018016725A2 BR 112018016725 A2 BR112018016725 A2 BR 112018016725A2 BR 112018016725 A BR112018016725 A BR 112018016725A BR 112018016725 A BR112018016725 A BR 112018016725A BR 112018016725 A2 BR112018016725 A2 BR 112018016725A2
Authority
BR
Brazil
Prior art keywords
sleep disorders
pharmaceutical composition
prevent
treat sleep
relates
Prior art date
Application number
BR112018016725A
Other languages
Portuguese (pt)
Inventor
Konstantinovich Syrov Kirill
Viktorovich Nesteruk Vladimir
Original Assignee
Valenta Intellekt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valenta Intellekt Ltd filed Critical Valenta Intellekt Ltd
Publication of BR112018016725A2 publication Critical patent/BR112018016725A2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

Abstract

a invenção se refere ao campo da medicina e à indústria químico-farmacêutica e refere-se aos agentes para uso no caso de transtornos do sono. uma composição farmacêutica para iniciar e manter o processo do sono e para prevenir, em animais e seres humanos, condições associadas a vários tipos de transtornos do sono, em que a dita composição é caracterizada por incluir quantidades eficazes de succinato de doxilamina e melatonina de liberação lenta. o resultado técnico consiste em efeitos terapêuticos sinérgicos, sucessão biológica e efeitos colaterais reduzidos.The invention relates to the field of medicine and the chemical-pharmaceutical industry and relates to agents for use in the case of sleep disorders. A pharmaceutical composition for initiating and maintaining the sleep process and for preventing, in animals and humans, conditions associated with various types of sleep disorders, wherein said composition is characterized by including effective amounts of doxylamine succinate and melatonin release. slow. The technical result consists of synergistic therapeutic effects, biological succession and reduced side effects.

BR112018016725A 2016-02-18 2017-02-16 pharmaceutical composition to prevent and treat sleep disorders BR112018016725A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2016105535A RU2620855C1 (en) 2016-02-18 2016-02-18 Pharmaceutical composition for sleep disorders prevention and treatment
PCT/RU2017/000077 WO2017142442A1 (en) 2016-02-18 2017-02-16 Pharmaceutical composition for preventing and treating sleep disorders

Publications (1)

Publication Number Publication Date
BR112018016725A2 true BR112018016725A2 (en) 2019-04-30

Family

ID=59032329

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018016725A BR112018016725A2 (en) 2016-02-18 2017-02-16 pharmaceutical composition to prevent and treat sleep disorders

Country Status (9)

Country Link
KR (1) KR20180101539A (en)
CN (1) CN108697645A (en)
BR (1) BR112018016725A2 (en)
CL (1) CL2018002337A1 (en)
EA (1) EA201891647A1 (en)
HK (1) HK1255631A1 (en)
MX (1) MX2018009921A (en)
RU (1) RU2620855C1 (en)
WO (1) WO2017142442A1 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007517040A (en) * 2003-12-24 2007-06-28 セプレイコー インコーポレイテッド Melatonin combination therapy to improve sleep quality
US9700548B2 (en) * 2011-06-09 2017-07-11 Requis Pharmaceuticals Inc. Antihistamines combined with dietary supplements for improved health
FR3000896B1 (en) * 2013-01-14 2016-08-26 Philippe Perovitch GALENIC FORM FOR ADMINISTRATION OF ACTIVE INGREDIENT (S) FOR ACCELERATED INDUCTION OF SLEEP AND / OR TREATMENT OF SLEEP DISORDERS
DK2964185T3 (en) * 2013-03-05 2022-02-14 Requis Pharmaceuticals Inc PREPARATIONS FOR THE TREATMENT OF SLEEP-RELATED RESPIRATORY DISORDERS

Also Published As

Publication number Publication date
CL2018002337A1 (en) 2018-11-30
MX2018009921A (en) 2018-11-09
KR20180101539A (en) 2018-09-12
HK1255631A1 (en) 2019-08-23
RU2620855C1 (en) 2017-05-30
EA201891647A1 (en) 2018-12-28
WO2017142442A1 (en) 2017-08-24
CN108697645A (en) 2018-10-23

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) [chapter 6.23 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements