BR112018011437A2 - process for the preparation of lisdexamphetamine - Google Patents

process for the preparation of lisdexamphetamine

Info

Publication number
BR112018011437A2
BR112018011437A2 BR112018011437A BR112018011437A BR112018011437A2 BR 112018011437 A2 BR112018011437 A2 BR 112018011437A2 BR 112018011437 A BR112018011437 A BR 112018011437A BR 112018011437 A BR112018011437 A BR 112018011437A BR 112018011437 A2 BR112018011437 A2 BR 112018011437A2
Authority
BR
Brazil
Prior art keywords
lisdexamphetamine
preparation
formula
pharmaceutically acceptable
acceptable salts
Prior art date
Application number
BR112018011437A
Other languages
Portuguese (pt)
Inventor
Sureshbhai Patel Nileshkumar
Thennati Rajamannar
Kilaru Srinivasu
Sridhar Pawar Sujit
Original Assignee
Sun Pharmaceutical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sun Pharmaceutical Ind Ltd filed Critical Sun Pharmaceutical Ind Ltd
Publication of BR112018011437A2 publication Critical patent/BR112018011437A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/16—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with acylated ring nitrogen atoms
    • C07D203/18—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with acylated ring nitrogen atoms by carboxylic acids, or by sulfur or nitrogen analogues thereof

Abstract

a presente invenção refere-se a um processo para a preparação de lisdexanfetamina e seus sais farmaceuticamente aceitáveis por meio de um novo intermediário de aziridina de fórmula iv.The present invention relates to a process for the preparation of lisdexamphetamine and its pharmaceutically acceptable salts by means of a novel aziridine intermediate of formula iv.

BR112018011437A 2015-12-11 2016-12-12 process for the preparation of lisdexamphetamine BR112018011437A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN4670MU2015 2015-12-11
PCT/IN2016/050441 WO2017098533A2 (en) 2015-12-11 2016-12-12 Process for preparation of lisdexamphetamine

Publications (1)

Publication Number Publication Date
BR112018011437A2 true BR112018011437A2 (en) 2018-11-27

Family

ID=59012856

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018011437A BR112018011437A2 (en) 2015-12-11 2016-12-12 process for the preparation of lisdexamphetamine

Country Status (4)

Country Link
EP (1) EP3386944A4 (en)
BR (1) BR112018011437A2 (en)
CA (1) CA3006537A1 (en)
WO (1) WO2017098533A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220151986A1 (en) 2020-11-18 2022-05-19 Mind Medicine, Inc. Mdma prodrugs to assist psychotherapy
EP4122914B1 (en) 2021-07-22 2023-08-16 SCI Pharmtech Inc Compound and method for preparation of lisdexamfetamine
US11608312B1 (en) 2021-07-22 2023-03-21 Sci Pharmtech Inc. Compound and method for preparation of lisdexamfetamine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1675555A4 (en) * 2003-09-30 2011-03-09 Shire Llc Pharmaceutical compositions for prevention of overdose or abuse
WO2010042120A1 (en) * 2008-10-09 2010-04-15 Archimica, Inc. Process for the synthesis of amphetamine derivatives
WO2010148305A1 (en) * 2009-06-19 2010-12-23 Cambrex Charles City, Inc. Methods and compositions for preparation of amphetamine conjugates and salts thereof
US8779191B2 (en) * 2010-12-20 2014-07-15 Cambrex Charles City, Inc. Methods and compositions for preparing lisdexamfetamine and salts thereof
WO2013011526A1 (en) * 2011-07-20 2013-01-24 Ind-Swift Laboratories Limited Process for preparation of lisdexamphetamine and salts thereof
WO2015130660A1 (en) * 2014-02-25 2015-09-03 Chemapotheca, Llc Synthesis of racemic amphetamine derivatives by cuprate addition reaction with aziridine phosphoramidate compounds

Also Published As

Publication number Publication date
EP3386944A2 (en) 2018-10-17
WO2017098533A3 (en) 2017-08-10
CA3006537A1 (en) 2017-06-15
EP3386944A4 (en) 2019-08-28
WO2017098533A2 (en) 2017-06-15

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired