BR112018008585A2 - peptide macrocycles against acinotobacter baumannii - Google Patents

peptide macrocycles against acinotobacter baumannii

Info

Publication number
BR112018008585A2
BR112018008585A2 BR112018008585A BR112018008585A BR112018008585A2 BR 112018008585 A2 BR112018008585 A2 BR 112018008585A2 BR 112018008585 A BR112018008585 A BR 112018008585A BR 112018008585 A BR112018008585 A BR 112018008585A BR 112018008585 A2 BR112018008585 A2 BR 112018008585A2
Authority
BR
Brazil
Prior art keywords
acinotobacter
baumannii
peptide macrocycles
macrocycles against
formula
Prior art date
Application number
BR112018008585A
Other languages
Portuguese (pt)
Inventor
Schaeublin Adrian
Alanine Alexander
Wahhab Amal
Fasching Bernhard
KROLL Carsten
ZAMPALONI Claudia
Macdonald Dwight
Hilpert Hans
Thomas Helmut
Shen Hong
BEIGNET Julien
Bleicher Konrad
Kolczewski Sabine
Jackson Stephen
Hu Taishan
Stoll Theodor
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority claimed from PCT/EP2016/075499 external-priority patent/WO2017072062A1/en
Publication of BR112018008585A2 publication Critical patent/BR112018008585A2/en

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

a presente invenção proporciona compostos da fórmula (i) em que x1 a x8 e r1 a r8 são tais como descritos neste contexto, bem como os seus sais farmaceuticamente aceitáveis. além disso, a presente invenção relaciona-se com a manufatura dos compostos da fórmula (i), composições farmacêuticas que compreendem os mesmos e seu uso como medicamentos para o tratamento de enfermidades e infecções causadas pelo acinotobacter baumannii.The present invention provides compounds of formula (I) wherein x1 to x8 and r1 to r8 are as described herein, as well as their pharmaceutically acceptable salts. furthermore, the present invention relates to the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments for the treatment of diseases and infections caused by acinotobacter baumannii.

BR112018008585A 2015-10-27 2016-10-24 peptide macrocycles against acinotobacter baumannii BR112018008585A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15191743 2015-10-27
PCT/EP2016/075499 WO2017072062A1 (en) 2015-10-27 2016-10-24 Peptide macrocycles against acinetobacter baumannii

Publications (1)

Publication Number Publication Date
BR112018008585A2 true BR112018008585A2 (en) 2018-10-30

Family

ID=54539821

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018008585A BR112018008585A2 (en) 2015-10-27 2016-10-24 peptide macrocycles against acinotobacter baumannii

Country Status (3)

Country Link
AR (1) AR106511A1 (en)
BR (1) BR112018008585A2 (en)
MA (1) MA43103B1 (en)

Also Published As

Publication number Publication date
MA43103B1 (en) 2020-08-31
AR106511A1 (en) 2018-01-24

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notice of approval relating to section 229 industrial property law
B06U Preliminary requirement: requests with searches performed by other patent offices: suspension of the patent application procedure