BR112017027332A2 - topical compositions comprising a corticosteroid and a retinoid for treating psoriasis. - Google Patents

topical compositions comprising a corticosteroid and a retinoid for treating psoriasis.

Info

Publication number
BR112017027332A2
BR112017027332A2 BR112017027332-2A BR112017027332A BR112017027332A2 BR 112017027332 A2 BR112017027332 A2 BR 112017027332A2 BR 112017027332 A BR112017027332 A BR 112017027332A BR 112017027332 A2 BR112017027332 A2 BR 112017027332A2
Authority
BR
Brazil
Prior art keywords
retinoid
corticosteroid
topical compositions
treating psoriasis
psoriasis
Prior art date
Application number
BR112017027332-2A
Other languages
Portuguese (pt)
Other versions
BR112017027332B1 (en
Inventor
J. Dow Gordon
Pillai Radhakrishnan
Bhatt Varsha
Original Assignee
Valeant Pharmaceuticals North America
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56131662&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112017027332(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Valeant Pharmaceuticals North America filed Critical Valeant Pharmaceuticals North America
Publication of BR112017027332A2 publication Critical patent/BR112017027332A2/en
Publication of BR112017027332B1 publication Critical patent/BR112017027332B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
BR112017027332-2A 2015-06-18 2016-06-06 Topical pharmaceutical composition to treat psoriasis and its use BR112017027332B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562181481P 2015-06-18 2015-06-18
US62/181,481 2015-06-18
PCT/US2016/035991 WO2016205001A1 (en) 2015-06-18 2016-06-06 Topical compositions comprising a corticosteroid and a retinoid for treating psoriasis

Publications (2)

Publication Number Publication Date
BR112017027332A2 true BR112017027332A2 (en) 2018-09-04
BR112017027332B1 BR112017027332B1 (en) 2023-11-07

Family

ID=56131662

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017027332-2A BR112017027332B1 (en) 2015-06-18 2016-06-06 Topical pharmaceutical composition to treat psoriasis and its use

Country Status (20)

Country Link
US (7) US10251895B2 (en)
EP (1) EP3310389B1 (en)
JP (1) JP6997624B2 (en)
KR (2) KR20240035898A (en)
CN (1) CN108282998B (en)
AU (1) AU2016279801B2 (en)
BR (1) BR112017027332B1 (en)
CA (1) CA2988577A1 (en)
CY (1) CY1123354T1 (en)
DK (1) DK3310389T3 (en)
ES (1) ES2812451T3 (en)
HR (1) HRP20201250T1 (en)
HU (1) HUE050603T2 (en)
LT (1) LT3310389T (en)
MX (1) MX2017015990A (en)
PL (1) PL3310389T3 (en)
PT (1) PT3310389T (en)
RS (1) RS60672B1 (en)
SI (1) SI3310389T1 (en)
WO (1) WO2016205001A1 (en)

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US11957753B2 (en) 2010-11-22 2024-04-16 Bausch Health Ireland Limited Pharmaceutical formulations containing corticosteroids for topical administration
AU2016279801B2 (en) 2015-06-18 2021-09-09 Valeant Pharmaceuticals North America Topical compositions comprising a corticosteroid and a retinoid for treating psoriasis
RU2699027C2 (en) * 2015-07-13 2019-09-03 Др. Редди'С Лабораториз Лтд. Retinoid compositions for topical application
US11311482B2 (en) 2017-05-12 2022-04-26 Bausch Health Us, Llc Topical compositions and methods for treating skin diseases
CA3063371A1 (en) * 2017-05-12 2018-11-15 Bausch Health Us, Llc Topical compositions and methods for treating skin diseases
CA3067657A1 (en) * 2017-06-23 2018-12-27 Laboratorios Salvat, S.A. An oil-in-water nanoemulsion composition of clobetasol
US10653656B2 (en) 2018-04-05 2020-05-19 Bausch Health Ireland Limited Topical pharmaceutical compositions for treating skin conditions
WO2019195802A1 (en) * 2018-04-05 2019-10-10 Bausch Health Ireland Limited Polymeric emulsion delivery systems
US10945952B2 (en) 2019-03-14 2021-03-16 Crescita Therapeutics Inc. Rinse-off compositions and uses thereof for delivery of active agents
KR102327827B1 (en) 2019-11-01 2021-11-18 한국과학기술연구원 Composition for improving psoriasis symptom comprising extract of Curcuma longa L and UV treatment
KR102451304B1 (en) 2020-09-14 2022-10-07 한국과학기술연구원 Composition for improving psoriasis symptom comprising extract of Thalictrum squarrosum steph
KR102527907B1 (en) 2020-09-14 2023-05-03 한국과학기술연구원 Composition for improving psoriasis symptom comprising extract of Sphallerocaprus gracilis
KR102461001B1 (en) 2020-09-14 2022-11-01 한국과학기술연구원 Composition for improving psoriasis symptom comprising extract of Dianthus superbus L.
KR20230041257A (en) 2021-09-17 2023-03-24 한국과학기술연구원 Composition for improving psoriasis symptom comprising cimicifugolide A
KR20230041255A (en) 2021-09-17 2023-03-24 한국과학기술연구원 Composition for improving psoriasis symptom comprising extract of Aruncus dioicus var. kamtschaticus
CN113975249B (en) * 2021-10-14 2023-01-03 中山大学·深圳 Preparation of Tris-BNP nano-particles and application thereof in treatment of skin diseases
CN113712918A (en) * 2021-10-28 2021-11-30 济南纽华医药科技有限公司 Apremilast microemulsion and preparation method thereof

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Also Published As

Publication number Publication date
WO2016205001A1 (en) 2016-12-22
US10426787B2 (en) 2019-10-01
LT3310389T (en) 2020-11-10
KR20180053292A (en) 2018-05-21
US20180177803A1 (en) 2018-06-28
AU2016279801B2 (en) 2021-09-09
US11679115B2 (en) 2023-06-20
PL3310389T3 (en) 2020-11-30
US20230086282A1 (en) 2023-03-23
US20210330681A1 (en) 2021-10-28
US11679116B2 (en) 2023-06-20
AU2016279801A1 (en) 2018-01-04
ES2812451T3 (en) 2021-03-17
CN108282998A (en) 2018-07-13
DK3310389T3 (en) 2020-08-10
PT3310389T (en) 2020-11-11
BR112017027332B1 (en) 2023-11-07
JP2018526325A (en) 2018-09-13
CY1123354T1 (en) 2021-12-31
MX2017015990A (en) 2018-11-09
KR102643849B1 (en) 2024-03-07
US20190231797A1 (en) 2019-08-01
KR20240035898A (en) 2024-03-18
EP3310389A1 (en) 2018-04-25
EP3310389B1 (en) 2020-07-01
JP6997624B2 (en) 2022-01-17
US11648256B2 (en) 2023-05-16
RS60672B1 (en) 2020-09-30
HRP20201250T1 (en) 2020-11-13
HUE050603T2 (en) 2020-12-28
US20160367570A1 (en) 2016-12-22
CA2988577A1 (en) 2016-12-22
US20210145847A1 (en) 2021-05-20
CN108282998B (en) 2021-07-06
US20230355640A1 (en) 2023-11-09
US10251895B2 (en) 2019-04-09
SI3310389T1 (en) 2020-11-30

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