BR112016028752A2 - ?método para puxar líquido passando uma barreira capilar, e, dispositivo útil para filtrar uma amostra líquida? - Google Patents

?método para puxar líquido passando uma barreira capilar, e, dispositivo útil para filtrar uma amostra líquida?

Info

Publication number
BR112016028752A2
BR112016028752A2 BR112016028752A BR112016028752A BR112016028752A2 BR 112016028752 A2 BR112016028752 A2 BR 112016028752A2 BR 112016028752 A BR112016028752 A BR 112016028752A BR 112016028752 A BR112016028752 A BR 112016028752A BR 112016028752 A2 BR112016028752 A2 BR 112016028752A2
Authority
BR
Brazil
Prior art keywords
capillary
small
pressure
useful
liquid
Prior art date
Application number
BR112016028752A
Other languages
English (en)
Other versions
BR112016028752B1 (pt
Inventor
Ryan Mcneely Michael
Original Assignee
Ryan Mcneely Michael
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ryan Mcneely Michael filed Critical Ryan Mcneely Michael
Publication of BR112016028752A2 publication Critical patent/BR112016028752A2/pt
Publication of BR112016028752B1 publication Critical patent/BR112016028752B1/pt

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B01D63/087—Single membrane modules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/20—Accessories; Auxiliary operations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B01D63/088—Microfluidic devices comprising semi-permeable flat membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/06—Specific process operations in the permeate stream
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/26—Further operations combined with membrane separation processes
    • B01D2311/2626—Absorption or adsorption
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/24—Specific pressurizing or depressurizing means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/025—Displaying results or values with integrated means
    • B01L2300/028—Graduation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4005—Concentrating samples by transferring a selected component through a membrane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Ecology (AREA)
  • Water Supply & Treatment (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • External Artificial Organs (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Measuring Fluid Pressure (AREA)

Abstract

muitos diagnósticos portáteis são limitados em suas funcionalidades devido à física desafiante associada com sistemas dimensionalmente pequenos. um exemplo disto são as forças capilares em sistemas hidrofílicos, tais como a retenção estanque de líquido passando através de uma membrana de filtração de poro pequeno, ou microfluídicos impulsionados pela força capilar onde, para manter o líquido fluindo as dimensões do sistema se tornam tão pequenas que as vazões são muito baixas para serem úteis, ou a fabricação de tais dispositivos se torna não econômica. esta descrição detalha métodos para ?reinicializar? a condição de força capilar para evitar a exigência de picos de pressão transientes associados com a pressão de ruptura de membranas de poro pequeno, e evitar a necessidade de canais microfluídicos extremamente pequenos, que podem ser úteis em aplicações tais como filtração de sangue integral para plasma usando apenas a pressão de sucção ou pressão capilar passiva.
BR112016028752-5A 2014-06-13 2015-06-07 Método para puxar líquido passando uma barreira capilar, e, dispositivo útil para filtrar uma amostra líquida BR112016028752B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462011661P 2014-06-13 2014-06-13
US62/011,661 2014-06-13
PCT/US2015/034608 WO2015191406A1 (en) 2014-06-13 2015-06-07 Capillary pressure re-set mechanism and applications

Publications (2)

Publication Number Publication Date
BR112016028752A2 true BR112016028752A2 (pt) 2017-08-22
BR112016028752B1 BR112016028752B1 (pt) 2022-02-15

Family

ID=54834132

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016028752-5A BR112016028752B1 (pt) 2014-06-13 2015-06-07 Método para puxar líquido passando uma barreira capilar, e, dispositivo útil para filtrar uma amostra líquida

Country Status (11)

Country Link
US (3) US10532325B2 (pt)
EP (1) EP3154666B1 (pt)
CN (1) CN106573201B (pt)
AU (1) AU2015275031B2 (pt)
BR (1) BR112016028752B1 (pt)
CA (1) CA2949863C (pt)
DK (1) DK3154666T3 (pt)
ES (1) ES2842239T3 (pt)
MX (2) MX2016016536A (pt)
MY (1) MY188120A (pt)
WO (1) WO2015191406A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11305236B2 (en) 2014-06-13 2022-04-19 Gattaco Inc. Surface tension driven filtration
MX2016016536A (es) 2014-06-13 2017-08-02 Ryan Mcneely Michael Mecanismo para reiniciar presion capilar y aplicaciones.
WO2017015243A1 (en) 2015-07-21 2017-01-26 Mcneely Michael Ryan Automatic plasma separation and metering
EP3629901A4 (en) * 2017-06-02 2021-09-01 Northwestern University EPIDERMAL SENSOR SYSTEMS FOR OPTICAL READING, VISUALIZATION AND ANALYSIS OF BIOLOGICAL LIQUIDS
ES2911016T3 (es) * 2018-06-07 2022-05-17 Becton Dickinson Co Dispositivo de separación de fluidos biológicos
CN113167785B (zh) * 2018-09-06 2024-09-03 卡皮台内尔公司 微流体装置
CN109499631A (zh) * 2018-11-19 2019-03-22 深圳拓扑精膜科技有限公司 一种集成阳极氧化铝多孔膜的微流体芯片
US11918999B2 (en) 2019-11-11 2024-03-05 Gattaco Inc. Interface to lateral flow

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EP0907412B1 (en) * 1996-06-28 2008-08-27 Caliper Life Sciences, Inc. High-throughput screening assay systems in microscale fluidic devices
WO2000022436A1 (en) * 1998-10-13 2000-04-20 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
US6811842B1 (en) * 1999-06-29 2004-11-02 The Procter & Gamble Company Liquid transport member for high flux rates between two port regions
DE10046173C2 (de) * 2000-09-08 2003-04-03 Inst Chemo Biosensorik Vorrichtung und Verfahren zur Separation von ungelösten Bestandteilen aus biologischen Flüssigkeiten
WO2003053348A2 (en) * 2001-12-12 2003-07-03 Hydration Technologies, Inc. Direct osmotic hydration devices
DE102004027422A1 (de) * 2004-06-04 2005-12-29 Boehringer Ingelheim Microparts Gmbh Vorrichtung zur Aufnahme von Blut und Abtrennung von Blutbestandteilen
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ES2352581T3 (es) * 2008-06-02 2011-02-21 Boehringer Ingelheim Microparts Gmbh Estructura de lámina microfluídica para dosificar líquidos.
US8318439B2 (en) * 2008-10-03 2012-11-27 Micronics, Inc. Microfluidic apparatus and methods for performing blood typing and crossmatching
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US9383293B2 (en) * 2010-04-23 2016-07-05 Boehringer Ingelheim Microparts Gmbh Device for plasma separation by means of a central channel structure
US8617395B2 (en) * 2010-09-30 2013-12-31 The United States Of America, As Represented By The Secretary Of Agriculture Thin film composite membranes and their method of preparation and use
US9528987B2 (en) * 2011-06-23 2016-12-27 University Of Washington Reagent patterning in capillarity-based analyzers and associated systems and methods
WO2014158660A1 (en) * 2013-03-14 2014-10-02 Dow Global Technologies Llc Composite polyamide membrane including dissolvable polymer coating
WO2015044454A2 (en) * 2013-09-30 2015-04-02 Göran Stemme A microfluidic device, use and methods
MX2016016536A (es) 2014-06-13 2017-08-02 Ryan Mcneely Michael Mecanismo para reiniciar presion capilar y aplicaciones.

Also Published As

Publication number Publication date
MY188120A (en) 2021-11-22
MX2016016536A (es) 2017-08-02
EP3154666A1 (en) 2017-04-19
CA2949863C (en) 2017-10-31
AU2015275031B2 (en) 2019-10-03
CN106573201A (zh) 2017-04-19
US20210229041A1 (en) 2021-07-29
EP3154666B1 (en) 2020-12-09
US20170087517A1 (en) 2017-03-30
MX2020012364A (es) 2021-01-20
US10870085B2 (en) 2020-12-22
AU2015275031A1 (en) 2017-01-12
CN106573201B (zh) 2020-05-22
DK3154666T3 (da) 2021-01-18
CA2949863A1 (en) 2015-12-17
US10532325B2 (en) 2020-01-14
WO2015191406A1 (en) 2015-12-17
US11426699B2 (en) 2022-08-30
ES2842239T3 (es) 2021-07-13
US20190336916A1 (en) 2019-11-07
BR112016028752B1 (pt) 2022-02-15
EP3154666A4 (en) 2018-02-21

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Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 07/06/2015, OBSERVADAS AS CONDICOES LEGAIS.