BR112016017680A2 - asymmetric interference mRNA compositions that silence k-ras and methods of using them - Google Patents
asymmetric interference mRNA compositions that silence k-ras and methods of using themInfo
- Publication number
- BR112016017680A2 BR112016017680A2 BR112016017680A BR112016017680A BR112016017680A2 BR 112016017680 A2 BR112016017680 A2 BR 112016017680A2 BR 112016017680 A BR112016017680 A BR 112016017680A BR 112016017680 A BR112016017680 A BR 112016017680A BR 112016017680 A2 BR112016017680 A2 BR 112016017680A2
- Authority
- BR
- Brazil
- Prior art keywords
- ras
- silence
- methods
- asymmetric interference
- mrna compositions
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
a invenção provê novas composições para uso em silenciamento de expressão de gene de k-ras. mais particularmente, a invenção provê novas moléculas de rna de interferência assimétrico como inibidores da expressão de k-ras, e as composições farmacêuticas e suas utilizações no tratamento de câncer ou de uma desordem relacionada em um mamífero.The invention provides novel compositions for use in k-ras gene expression silencing. more particularly, the invention provides novel asymmetric interference RNA molecules as inhibitors of k-ras expression, and pharmaceutical compositions and their uses in the treatment of cancer or a related disorder in a mammal.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461953590P | 2014-03-14 | 2014-03-14 | |
US201561121721P | 2015-02-27 | 2015-02-27 | |
PCT/US2015/020776 WO2015139044A1 (en) | 2014-03-14 | 2015-03-16 | Asymmetric interfering rna compositions that silence k-ras and methods of uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112016017680A2 true BR112016017680A2 (en) | 2018-01-23 |
Family
ID=62598787
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016017680A BR112016017680A2 (en) | 2014-03-14 | 2015-03-16 | asymmetric interference mRNA compositions that silence k-ras and methods of using them |
Country Status (1)
Country | Link |
---|---|
BR (1) | BR112016017680A2 (en) |
-
2015
- 2015-03-16 BR BR112016017680A patent/BR112016017680A2/en not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE A 5A ANUIDADE. |
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B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2558 DE 14/01/2020. |