BR112016016966A2 - process to produce a polymer - Google Patents
process to produce a polymerInfo
- Publication number
- BR112016016966A2 BR112016016966A2 BR112016016966A BR112016016966A BR112016016966A2 BR 112016016966 A2 BR112016016966 A2 BR 112016016966A2 BR 112016016966 A BR112016016966 A BR 112016016966A BR 112016016966 A BR112016016966 A BR 112016016966A BR 112016016966 A2 BR112016016966 A2 BR 112016016966A2
- Authority
- BR
- Brazil
- Prior art keywords
- glucopyranosyl
- polymer
- main chain
- linear
- microorganism
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
Abstract
processo para produzir um polímero que consiste em uma cadeia principal linear de unidades de ß-d-(1-3)-glucopiranosil tendo uma unidade de ß-d-glucopiranosil (1-6) simples ligada a uma unidade de ß-d-glucopiranosil da cadeia principal linear com um grau de ramificação médio de cerca de 0,3, o dito processo compreendendo as etapas de: (i) cultivar em um meio um micro-organismo geneticamente modificado capaz de produzir um polímero que consiste em uma cadeia principal linear de unidades de ß-d-(1-3)-glucopiranosil tendo uma unidade de ß-d-glucopiranosil (1-6) ligada a uma unidade de ß-d-glucopiranosil da cadeia principal linear com um grau de ramificação médio de cerca de 0,3, em que a modificação confere atividade diminuída em comparação com um micro-organismo de controle não modificado da mesma cepa de um produto de gene hom2 sob condições que permitem que os ditos micro-organismo produzam o dito polímero; (ii) recuperar opcionalmente o dito polímero do meio.A process for producing a polymer consisting of a linear backbone of ß-d- (1-3) -glucopyranosyl units having a single ß-d-glucopyranosyl (1-6) unit attached to a ß-d- linear main chain glucopyranosyl with an average branching degree of about 0.3, said process comprising the steps of: (i) cultivating in a medium a genetically modified microorganism capable of producing a polymer consisting of a main chain linear sequence of ß-d- (1-3) -glucopyranosyl units having a ß-d-glucopyranosyl (1-6) moiety attached to a linear main chain ß-d-glucopyranosyl moiety with an average branching degree of about 0.3, wherein the modification confers decreased activity compared to an unmodified control microorganism of the same strain of a hom2 gene product under conditions that allow said microorganism to produce said polymer; (ii) optionally recovering said medium polymer.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14152338 | 2014-01-23 | ||
| PCT/EP2014/077678 WO2015110218A1 (en) | 2014-01-23 | 2014-12-15 | Process for producing a beta-glucan polymer and genetically modified microorganisms useful in this process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112016016966A2 true BR112016016966A2 (en) | 2018-01-23 |
Family
ID=49999765
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112016016966A BR112016016966A2 (en) | 2014-01-23 | 2014-12-15 | process to produce a polymer |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP3097198A1 (en) |
| KR (1) | KR20160108557A (en) |
| CN (1) | CN106414757A (en) |
| BR (1) | BR112016016966A2 (en) |
| CA (1) | CA2937359A1 (en) |
| MX (1) | MX2016009610A (en) |
| RU (1) | RU2016134228A (en) |
| WO (1) | WO2015110218A1 (en) |
| ZA (1) | ZA201605746B (en) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112015000032A2 (en) * | 2012-07-04 | 2017-08-08 | Basf Se | genetically modified microorganism, use of a polynucleotide, and method of producing a polymer |
-
2014
- 2014-12-15 KR KR1020167022917A patent/KR20160108557A/en not_active Application Discontinuation
- 2014-12-15 MX MX2016009610A patent/MX2016009610A/en unknown
- 2014-12-15 WO PCT/EP2014/077678 patent/WO2015110218A1/en active Application Filing
- 2014-12-15 RU RU2016134228A patent/RU2016134228A/en not_active Application Discontinuation
- 2014-12-15 CN CN201480073867.8A patent/CN106414757A/en not_active Withdrawn
- 2014-12-15 EP EP14812236.9A patent/EP3097198A1/en not_active Withdrawn
- 2014-12-15 CA CA2937359A patent/CA2937359A1/en not_active Abandoned
- 2014-12-15 BR BR112016016966A patent/BR112016016966A2/en not_active Application Discontinuation
-
2016
- 2016-08-18 ZA ZA2016/05746A patent/ZA201605746B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201605746B (en) | 2018-05-30 |
| CA2937359A1 (en) | 2015-07-30 |
| CN106414757A (en) | 2017-02-15 |
| RU2016134228A (en) | 2018-03-01 |
| KR20160108557A (en) | 2016-09-19 |
| WO2015110218A1 (en) | 2015-07-30 |
| EP3097198A1 (en) | 2016-11-30 |
| MX2016009610A (en) | 2016-11-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired |