BR112015023795A2 - computer systems, computer readable media and antibody characterization methods - Google Patents

computer systems, computer readable media and antibody characterization methods

Info

Publication number
BR112015023795A2
BR112015023795A2 BR112015023795A BR112015023795A BR112015023795A2 BR 112015023795 A2 BR112015023795 A2 BR 112015023795A2 BR 112015023795 A BR112015023795 A BR 112015023795A BR 112015023795 A BR112015023795 A BR 112015023795A BR 112015023795 A2 BR112015023795 A2 BR 112015023795A2
Authority
BR
Brazil
Prior art keywords
points
computer
computer readable
series
protein
Prior art date
Application number
BR112015023795A
Other languages
Portuguese (pt)
Inventor
Max Woodhead David
A Lacey Jeffrey
Park Shawna
Marmer Steve
Original Assignee
Battelle Energy Alliance Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Battelle Energy Alliance Llc filed Critical Battelle Energy Alliance Llc
Publication of BR112015023795A2 publication Critical patent/BR112015023795A2/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/66—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Cell Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

resumo “sistemas de computação, meios legíveis por computador e métodos de caracterização de anticorpos” sistemas de computação, meios e métodos legíveis por computador são di-vulgados. no sistema de computação, um dispositivo de captura de imagem capta uma imagem de uma série de proteínas, incluindo pontos de proteínas pré-determinadas, no qual alguns dos pontos se ligaram a um material biológico pos-suindo anticorpos específicos para indivíduos para formar complexos imunes e al-guns dos complexos imunes interagiram com um agente de detecção para produzir uma imagem visível da mesma. o sistema de computação pode ser operativamente ligado ao dispositivo de captura de imagem e processa a imagem captada da série de proteínas a para determinar os locais de controle de uma pluralidade de pontos de controle em locais conhecidos na série de proteínas. o sistema de computação também extrapola locais esperados de todos os outros pontos na série de proteínas a partir dos locais de controle.abstract “computer systems, computer readable media and antibody characterization methods” computer systems, media and computer readable methods are disclosed. In the computer system, an image capture device captures an image of a series of proteins, including predetermined protein points, in which some of the points have bound to a biological material having individual-specific antibodies to form immune complexes. and some of the immune complexes interacted with a detection agent to produce a visible image thereof. The computing system may be operably connected to the imaging device and processes the captured image from the protein series a to determine the control sites of a plurality of control points at known locations in the protein series. The computing system also extrapolates expected locations from all other points in the protein series from the control locations.

BR112015023795A 2013-03-15 2014-03-13 computer systems, computer readable media and antibody characterization methods BR112015023795A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361786961P 2013-03-15 2013-03-15
PCT/US2014/025561 WO2014151360A1 (en) 2013-03-15 2014-03-13 Computing systems, computer-readable media and methods of antibody profiling

Publications (1)

Publication Number Publication Date
BR112015023795A2 true BR112015023795A2 (en) 2017-07-18

Family

ID=51580940

Family Applications (2)

Application Number Title Priority Date Filing Date
BR112015023795A BR112015023795A2 (en) 2013-03-15 2014-03-13 computer systems, computer readable media and antibody characterization methods
BR112015023732A BR112015023732A2 (en) 2013-03-15 2014-03-13 method for identifying a source of a biological material, system and, computer readable storage media

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR112015023732A BR112015023732A2 (en) 2013-03-15 2014-03-13 method for identifying a source of a biological material, system and, computer readable storage media

Country Status (4)

Country Link
EP (1) EP2971281A4 (en)
BR (2) BR112015023795A2 (en)
CA (1) CA2907147A1 (en)
WO (1) WO2014151360A1 (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040181342A1 (en) * 1999-10-12 2004-09-16 Yi-Xiong Zhou System and method for automatically analyzing gene expression spots in a microarray
WO2005090546A1 (en) * 2004-03-19 2005-09-29 Detroit R & D, Inc. Chip production, hybridization and data interpretation for antibody and protein microarrays
US20080144899A1 (en) * 2006-11-30 2008-06-19 Manoj Varma Process for extracting periodic features from images by template matching
US8014577B2 (en) * 2007-01-29 2011-09-06 Institut National D'optique Micro-array analysis system and method thereof
US8969009B2 (en) * 2009-09-17 2015-03-03 Vicki S. Thompson Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual

Also Published As

Publication number Publication date
BR112015023732A2 (en) 2017-07-18
CA2907147A1 (en) 2014-09-25
WO2014151360A1 (en) 2014-09-25
EP2971281A1 (en) 2016-01-20
EP2971281A4 (en) 2016-11-02

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Legal Events

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B08F Application fees: dismissal - article 86 of industrial property law
B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)