BR112015021186A2 - processo para a preparação de (2s,5r)-7-oxo-6-sulfóxi-2-[((3r)-pirrolidina-3-carbonil)-hidrazino carbonil]-1,6-diaza-biciclo[3.2.1]octano - Google Patents

processo para a preparação de (2s,5r)-7-oxo-6-sulfóxi-2-[((3r)-pirrolidina-3-carbonil)-hidrazino carbonil]-1,6-diaza-biciclo[3.2.1]octano

Info

Publication number
BR112015021186A2
BR112015021186A2 BR112015021186A BR112015021186A BR112015021186A2 BR 112015021186 A2 BR112015021186 A2 BR 112015021186A2 BR 112015021186 A BR112015021186 A BR 112015021186A BR 112015021186 A BR112015021186 A BR 112015021186A BR 112015021186 A2 BR112015021186 A2 BR 112015021186A2
Authority
BR
Brazil
Prior art keywords
carbonyl
sulfoxy
diaza
bicyclo
pyrrolidine
Prior art date
Application number
BR112015021186A
Other languages
English (en)
Inventor
Chandra Mishra Amit
Vithalbhai Patel Mahesh
Keshav Deshpande Prasad
Dattatraya Yeole Ravindra
Bhawsar Satish
Sampatrao Pawar Shivaji
Bhaginath Jadhav Sunil
Rane Vipul
Original Assignee
Wockhardt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wockhardt Ltd filed Critical Wockhardt Ltd
Publication of BR112015021186A2 publication Critical patent/BR112015021186A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

resumo patente de invenção: "processo para a preparação de (2s,5r)-7-oxo-6-sulfóxi-2-[((3r)-pirrolidina-3-carbonil)-hidrazino carbonil]-1,6-diaza-biciclo[3.2.1]octano". é divulgado um processo para preparação de (2s,5r)-7-oxo-6-sulfóxi-2-[((3r)-pirrolidina-3-carbonil)-hidrazino carbonil]-1,6-diaza-biciclo[3.2.1]octano incluindo a reação de um composto de fórmula (ii) com um composto de fórmula (iii) para obter um composto de fórmula (iv). o produto final cristalino é conforme reivindicado.
BR112015021186A 2013-03-08 2013-10-12 processo para a preparação de (2s,5r)-7-oxo-6-sulfóxi-2-[((3r)-pirrolidina-3-carbonil)-hidrazino carbonil]-1,6-diaza-biciclo[3.2.1]octano BR112015021186A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN715MU2013 2013-03-08
PCT/IB2013/059327 WO2014135932A1 (en) 2013-03-08 2013-10-12 A process for preparation of (2s, 5r)-7-oxo-6-sulphooxy-2-[((3r)-pyrrolidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo[3.2.1]octane

Publications (1)

Publication Number Publication Date
BR112015021186A2 true BR112015021186A2 (pt) 2017-07-18

Family

ID=54250567

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015021186A BR112015021186A2 (pt) 2013-03-08 2013-10-12 processo para a preparação de (2s,5r)-7-oxo-6-sulfóxi-2-[((3r)-pirrolidina-3-carbonil)-hidrazino carbonil]-1,6-diaza-biciclo[3.2.1]octano

Country Status (13)

Country Link
US (1) US9624222B2 (pt)
EP (1) EP3013830A1 (pt)
JP (2) JP6285970B2 (pt)
KR (1) KR101774133B1 (pt)
CN (1) CN105008359B (pt)
AU (1) AU2013380575B2 (pt)
BR (1) BR112015021186A2 (pt)
CA (1) CA2904082C (pt)
MX (1) MX2015011721A (pt)
NZ (1) NZ711328A (pt)
RU (1) RU2625304C2 (pt)
WO (1) WO2014135932A1 (pt)
ZA (1) ZA201506342B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX366948B (es) * 2012-05-30 2019-07-30 Meiji Seika Pharma Co Ltd Nuevo inhibidor de beta-lactamasa y proceso para prepararlo.
EP3013829A1 (en) * 2013-03-08 2016-05-04 Wockhardt Limited A process for sodium salt of (2s, 5r)-2-carboxamido-7-oxo-6-sulfooxy -1,6-diaza-bicyclo[3.2.1]octane
CA2904084C (en) * 2013-03-08 2017-03-28 Wockhardt Limited A process for preparation of (2s, 5r)- sulfuric acid mono-{[(4-aminopiperidin-4-yl) carbonyl]-7-oxo-1,6-diaza-bicyclo[3.2.1]-oct-6-yl} ester

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9408450A (pt) * 1993-12-29 1997-08-05 Pfizer Antagonistas da neuroquinina diazabiciclicos
MY162532A (en) 2008-01-18 2017-06-15 Merck Sharp & Dohme Beta-lactamase inhibitors
FR2951171A1 (fr) * 2009-10-09 2011-04-15 Novexel Nouveau sel de sodium d'un compose azabicyclique sous forme enantiomere cristallisee et nouvelles formes polymorphes et pseudopolymorphes ainsi que leur preparation
JP2011160817A (ja) * 2010-02-04 2011-08-25 Univ Of Tokyo 移植支援材料
CA2822758C (en) * 2010-12-22 2018-03-20 Meiji Seika Pharma Co., Ltd. Optically active diazabicyclooctane derivative and process for preparing the same
MX348974B (es) * 2011-08-27 2017-07-04 Wockhardt Ltd Derivados 1,6 - diazabiciclo [3,2,1] octan-7-ona y su uso en el tratamiento de infecciones bacterianas.

Also Published As

Publication number Publication date
NZ711328A (en) 2016-06-24
US9624222B2 (en) 2017-04-18
ZA201506342B (en) 2016-12-21
CN105008359A (zh) 2015-10-28
JP6285970B2 (ja) 2018-02-28
CA2904082A1 (en) 2014-09-12
EP3013830A1 (en) 2016-05-04
CN105008359B (zh) 2018-01-23
JP2016515102A (ja) 2016-05-26
AU2013380575B2 (en) 2016-07-07
US20160002234A1 (en) 2016-01-07
KR101774133B1 (ko) 2017-09-01
KR20150123320A (ko) 2015-11-03
CA2904082C (en) 2017-10-03
AU2013380575A1 (en) 2015-09-10
RU2015142483A (ru) 2017-04-13
RU2625304C2 (ru) 2017-07-13
JP2018058895A (ja) 2018-04-12
WO2014135932A1 (en) 2014-09-12
MX2015011721A (es) 2015-12-01

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B06I Technical and formal requirements: publication cancelled

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B07E Notice of approval relating to section 229 industrial property law
B06U Preliminary requirement: requests with searches performed by other patent offices: suspension of the patent application procedure
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements