BR112015019748A2 - Peptídeo tendo atividade inibitória da pl e/ou pla2, produto alimentício adequado para o tratamento da obesidade e/ou estresse oxidativo, e, uso de streptococcus thermophilus cncm i-2776 e/ou streptococcus thermophilus cncm i-1630 e/ou lactobacillus paracasei subsp paracasei cncm i-4270 - Google Patents
Peptídeo tendo atividade inibitória da pl e/ou pla2, produto alimentício adequado para o tratamento da obesidade e/ou estresse oxidativo, e, uso de streptococcus thermophilus cncm i-2776 e/ou streptococcus thermophilus cncm i-1630 e/ou lactobacillus paracasei subsp paracasei cncm i-4270Info
- Publication number
- BR112015019748A2 BR112015019748A2 BR112015019748A BR112015019748A BR112015019748A2 BR 112015019748 A2 BR112015019748 A2 BR 112015019748A2 BR 112015019748 A BR112015019748 A BR 112015019748A BR 112015019748 A BR112015019748 A BR 112015019748A BR 112015019748 A2 BR112015019748 A2 BR 112015019748A2
- Authority
- BR
- Brazil
- Prior art keywords
- cncm
- streptococcus thermophilus
- obesity
- treatment
- oxidative stress
- Prior art date
Links
- LWGJTAZLEJHCPA-UHFFFAOYSA-N n-(2-chloroethyl)-n-nitrosomorpholine-4-carboxamide Chemical compound ClCCN(N=O)C(=O)N1CCOCC1 LWGJTAZLEJHCPA-UHFFFAOYSA-N 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 208000008589 Obesity Diseases 0.000 title abstract 3
- 235000013305 food Nutrition 0.000 title abstract 3
- 235000020824 obesity Nutrition 0.000 title abstract 3
- 230000036542 oxidative stress Effects 0.000 title abstract 3
- 241000186605 Lactobacillus paracasei Species 0.000 title abstract 2
- 102100026918 Phospholipase A2 Human genes 0.000 title abstract 2
- 101710096328 Phospholipase A2 Proteins 0.000 title abstract 2
- 241000194020 Streptococcus thermophilus Species 0.000 title abstract 2
- 241001312556 Streptococcus thermophilus CNCM I-1630 Species 0.000 title abstract 2
- 230000002401 inhibitory effect Effects 0.000 title abstract 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 239000004471 Glycine Substances 0.000 abstract 1
- 241000186660 Lactobacillus Species 0.000 abstract 1
- 241000194017 Streptococcus Species 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 229940039696 lactobacillus Drugs 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 239000006228 supernatant Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/168—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/165—Paracasei
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/21—Streptococcus, lactococcus
- A23V2400/249—Thermophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Zoology (AREA)
- Polymers & Plastics (AREA)
- Medical Informatics (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PEPTÍDEO TENDO ATIVIDADE INIBITÓRIA DA PL E/OU PLA2, PRODUTO ALIMENTÍCIO ADEQUADO PARA O TRATAMENTO DA OBESIDADE E/OU ESTRESSE OXIDATIVO, E, USO DE STREPTOCOCCUS THERMOPHILUS CNCM I-2776 E/OU STREPTOCOCCUS THERMOPHILUS CNCM I-1630 E/OU LACTOBACILLUS PARACASEI SUBSP PARACASEI CNCM I-4270. A presente invenção refere-se a certos peptídeos obteníveis por meio da hidrólise a partir da glicina de soja por meio da ação das culturas sobrenadantes das cepas pertencentes ao gênero Lactobacillus ou Streptococcus. Estes peptídeos, extratos contendo-os e produtos alimentícios contendo-os são úteis para o tratamento e/ou prevenção da obesidade e estresse oxidativo.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2013/053233 WO2014127798A1 (en) | 2013-02-19 | 2013-02-19 | Functional peptides for obesity disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015019748A2 true BR112015019748A2 (pt) | 2017-08-22 |
Family
ID=47722294
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015019748A BR112015019748A2 (pt) | 2013-02-19 | 2013-02-19 | Peptídeo tendo atividade inibitória da pl e/ou pla2, produto alimentício adequado para o tratamento da obesidade e/ou estresse oxidativo, e, uso de streptococcus thermophilus cncm i-2776 e/ou streptococcus thermophilus cncm i-1630 e/ou lactobacillus paracasei subsp paracasei cncm i-4270 |
Country Status (10)
Country | Link |
---|---|
US (1) | US9802990B2 (pt) |
EP (1) | EP2958578B1 (pt) |
JP (1) | JP2016508510A (pt) |
CN (1) | CN105163748B (pt) |
BR (1) | BR112015019748A2 (pt) |
CA (1) | CA2897742A1 (pt) |
ES (1) | ES2676436T3 (pt) |
MX (1) | MX2015010694A (pt) |
RU (1) | RU2015132368A (pt) |
WO (1) | WO2014127798A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114835784A (zh) * | 2015-07-16 | 2022-08-02 | 努里塔斯有限公司 | 抗炎肽及其用途 |
WO2017010133A1 (ja) * | 2015-07-16 | 2017-01-19 | サントリーホールディングス株式会社 | 動植物由来ペプチド含有血清カルノシン分解酵素阻害用組成物 |
SG11201804647TA (en) | 2015-12-04 | 2018-06-28 | Global Blood Therapeutics Inc | Dosing regimens for 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde |
KR101887576B1 (ko) * | 2016-04-15 | 2018-08-13 | (주)케어젠 | 항비만 및 항당뇨 효능을 갖는 펩타이드 및 이의 용도 |
TWI718402B (zh) * | 2018-08-16 | 2021-02-11 | 葡萄王生技股份有限公司 | 副乾酪乳酸桿菌gks6之活性物質、含其之組合物及其促進長壽之用途 |
CN116491631A (zh) * | 2023-05-26 | 2023-07-28 | 青岛农业大学 | 一种预制菜红烧肉及其制备方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2960947B2 (ja) | 1989-12-25 | 1999-10-12 | 日清製粉株式会社 | 脂質分解酵素阻害剤 |
EP1529114A1 (en) * | 2002-08-09 | 2005-05-11 | Chr. Hansen A/S | Process for preparing peptides with anti-hypertensive properties |
JP2004099447A (ja) * | 2002-09-04 | 2004-04-02 | Kyowa Hakko Kogyo Co Ltd | コレステロール低減化ペプチド |
US20060204617A1 (en) * | 2003-08-08 | 2006-09-14 | Astrid Hauser | Fermented food product comprising soy protein |
FR2876876B1 (fr) * | 2004-10-22 | 2007-02-16 | Gervais Danone Sa | Protection d'ingredients alimentaires bioactifs par l'utilisation de microorganismes presentant une capacite de metabolisation reduite |
US9034402B2 (en) | 2007-04-16 | 2015-05-19 | Solae, Llc | Protein hydrolysate compositions having improved sensory characteristics and physical properties |
FR2929511B1 (fr) * | 2008-04-02 | 2010-12-31 | Basf Beauty Care Solutions France Sas | Nouveau principe actif stimulant la proliferation et/ou l'activite des fibroblastes. |
EP2545160B1 (en) * | 2010-03-12 | 2018-07-18 | Compagnie Gervais Danone | Lactic acid bacteria for coeliac disease |
JP2012116817A (ja) * | 2010-12-03 | 2012-06-21 | Fuji Oil Co Ltd | 蛋白質組成物の加水分解物を含有する抗酸化剤 |
JP5686680B2 (ja) * | 2011-06-24 | 2015-03-18 | カルピス株式会社 | 乳酸菌発酵によるカゼイン由来ペプチドの製造方法 |
-
2013
- 2013-02-19 RU RU2015132368A patent/RU2015132368A/ru not_active Application Discontinuation
- 2013-02-19 JP JP2015557337A patent/JP2016508510A/ja active Pending
- 2013-02-19 CA CA2897742A patent/CA2897742A1/en not_active Abandoned
- 2013-02-19 EP EP13704797.3A patent/EP2958578B1/en active Active
- 2013-02-19 BR BR112015019748A patent/BR112015019748A2/pt not_active IP Right Cessation
- 2013-02-19 ES ES13704797.3T patent/ES2676436T3/es active Active
- 2013-02-19 CN CN201380073349.1A patent/CN105163748B/zh active Active
- 2013-02-19 WO PCT/EP2013/053233 patent/WO2014127798A1/en active Application Filing
- 2013-02-19 MX MX2015010694A patent/MX2015010694A/es unknown
- 2013-02-19 US US14/768,823 patent/US9802990B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2014127798A1 (en) | 2014-08-28 |
US9802990B2 (en) | 2017-10-31 |
CN105163748A (zh) | 2015-12-16 |
US20160002303A1 (en) | 2016-01-07 |
CA2897742A1 (en) | 2014-08-28 |
MX2015010694A (es) | 2016-04-25 |
RU2015132368A (ru) | 2017-03-27 |
EP2958578A1 (en) | 2015-12-30 |
CN105163748B (zh) | 2017-11-21 |
JP2016508510A (ja) | 2016-03-22 |
EP2958578B1 (en) | 2018-04-11 |
ES2676436T3 (es) | 2018-07-19 |
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