BR112014031899A2 - sem titulo - Google Patents
sem tituloInfo
- Publication number
- BR112014031899A2 BR112014031899A2 BR112014031899A BR112014031899A BR112014031899A2 BR 112014031899 A2 BR112014031899 A2 BR 112014031899A2 BR 112014031899 A BR112014031899 A BR 112014031899A BR 112014031899 A BR112014031899 A BR 112014031899A BR 112014031899 A2 BR112014031899 A2 BR 112014031899A2
- Authority
- BR
- Brazil
- Prior art keywords
- untitled
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261662300P | 2012-06-20 | 2012-06-20 | |
| PCT/US2013/046645 WO2013192346A1 (en) | 2012-06-20 | 2013-06-19 | Substituted bicyclic alkoxy pyrazole analogs as allosteric modulators of mglur5 receptors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112014031899A2 true BR112014031899A2 (pt) | 2017-06-27 |
| BR112014031899A8 BR112014031899A8 (pt) | 2017-10-24 |
Family
ID=49769351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014031899A BR112014031899A8 (pt) | 2012-06-20 | 2013-06-19 | composto, composição farmacêutica, e, método para tratamento de um distúrbio |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9029366B2 (pt) |
| EP (1) | EP2863912A4 (pt) |
| JP (1) | JP2015520240A (pt) |
| KR (1) | KR20150032304A (pt) |
| CN (1) | CN104797255A (pt) |
| AU (1) | AU2013277155A1 (pt) |
| BR (1) | BR112014031899A8 (pt) |
| CA (1) | CA2876969A1 (pt) |
| IL (1) | IL236326A0 (pt) |
| MX (1) | MX2014014911A (pt) |
| RU (1) | RU2015101512A (pt) |
| SG (1) | SG11201408503QA (pt) |
| WO (1) | WO2013192346A1 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104797255A (zh) | 2012-06-20 | 2015-07-22 | 范德比尔特大学 | 作为mglur5受体变构调节剂的取代的双环烷氧基吡唑类似物 |
| EP2863922A4 (en) * | 2012-06-20 | 2015-11-04 | Univ Vanderbilt | SUBSTITUTED BICYCLIC ALKOXYPYRAZOL ANALOGUES AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS |
| WO2015129821A1 (ja) * | 2014-02-27 | 2015-09-03 | 国立大学法人東京大学 | オートタキシン阻害活性を有する縮合ピラゾール誘導体 |
| MX371197B (es) * | 2015-02-11 | 2020-01-22 | Sunovion Pharmaceuticals Inc | Compuestos de dihidro-4h-pirazolo [5,1-c] [1,4] oxazinilo y análogos para el tratamiento de trastornos del sistema nervioso central (snc). |
| WO2016179351A1 (en) | 2015-05-05 | 2016-11-10 | Northwestern University | Treatment of levodopa-induced dyskinesias |
| US10196403B2 (en) | 2016-07-29 | 2019-02-05 | Sunovion Pharmaceuticals Inc. | Compounds and compositions and uses thereof |
| CA3032141A1 (en) | 2016-07-29 | 2018-02-01 | Vadim ALEXANDROV | Compounds and compositions and uses thereof |
| BR112020001433A2 (pt) | 2017-08-02 | 2020-07-28 | Sunovion Pharmaceuticals Inc. | compostos de isocromano e usos dos mesmos |
| US11136304B2 (en) | 2019-03-14 | 2021-10-05 | Sunovion Pharmaceuticals Inc. | Salts of a heterocyclic compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200423930A (en) | 2003-02-18 | 2004-11-16 | Hoffmann La Roche | Non-nucleoside reverse transcriptase inhibitors |
| CN102282147B (zh) * | 2009-01-28 | 2015-09-30 | 卡拉治疗学股份有限公司 | 二环吡唑并-杂环 |
| US9163015B2 (en) | 2010-02-11 | 2015-10-20 | Vanderbilt University | Pyrazolopyridine, pyrarolopyrazine, pyrazolopyrimidine, pyrazolothiophene and pyrazolothiazole compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction |
| US8946223B2 (en) * | 2010-04-12 | 2015-02-03 | Millennium Pharmaceuticals, Inc. | Substituted hydroxamic acids and uses thereof |
| CA2820262A1 (en) | 2010-12-08 | 2012-06-14 | Vanderbilt University | Bicyclic pyrazole compounds as allosteric modulators of mglur5 receptors |
| CN104797255A (zh) | 2012-06-20 | 2015-07-22 | 范德比尔特大学 | 作为mglur5受体变构调节剂的取代的双环烷氧基吡唑类似物 |
-
2013
- 2013-06-19 CN CN201380043159.5A patent/CN104797255A/zh active Pending
- 2013-06-19 EP EP13807306.9A patent/EP2863912A4/en not_active Withdrawn
- 2013-06-19 MX MX2014014911A patent/MX2014014911A/es unknown
- 2013-06-19 BR BR112014031899A patent/BR112014031899A8/pt not_active IP Right Cessation
- 2013-06-19 CA CA2876969A patent/CA2876969A1/en not_active Abandoned
- 2013-06-19 US US13/922,223 patent/US9029366B2/en not_active Expired - Fee Related
- 2013-06-19 SG SG11201408503QA patent/SG11201408503QA/en unknown
- 2013-06-19 AU AU2013277155A patent/AU2013277155A1/en not_active Abandoned
- 2013-06-19 JP JP2015518564A patent/JP2015520240A/ja active Pending
- 2013-06-19 WO PCT/US2013/046645 patent/WO2013192346A1/en active Application Filing
- 2013-06-19 RU RU2015101512A patent/RU2015101512A/ru unknown
- 2013-06-19 KR KR20157001536A patent/KR20150032304A/ko not_active Application Discontinuation
-
2014
- 2014-12-17 IL IL236326A patent/IL236326A0/en unknown
-
2015
- 2015-04-03 US US14/678,684 patent/US20150216863A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20150032304A (ko) | 2015-03-25 |
| US20150216863A1 (en) | 2015-08-06 |
| US9029366B2 (en) | 2015-05-12 |
| CN104797255A (zh) | 2015-07-22 |
| AU2013277155A1 (en) | 2015-01-22 |
| EP2863912A4 (en) | 2015-11-04 |
| CA2876969A1 (en) | 2013-12-27 |
| MX2014014911A (es) | 2015-05-15 |
| WO2013192346A9 (en) | 2014-12-18 |
| BR112014031899A8 (pt) | 2017-10-24 |
| WO2013192346A1 (en) | 2013-12-27 |
| EP2863912A1 (en) | 2015-04-29 |
| RU2015101512A (ru) | 2016-08-10 |
| SG11201408503QA (en) | 2015-01-29 |
| JP2015520240A (ja) | 2015-07-16 |
| US20130345203A1 (en) | 2013-12-26 |
| IL236326A0 (en) | 2015-02-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |