BR112014024256A8 - Composição biorrelevante homogênea, meio biorrelevante aquoso, métodos de preparar um meio biorrelevante aquoso e uma composição homogênea, e, uso do meio biorrelevante aquoso - Google Patents
Composição biorrelevante homogênea, meio biorrelevante aquoso, métodos de preparar um meio biorrelevante aquoso e uma composição homogênea, e, uso do meio biorrelevante aquosoInfo
- Publication number
- BR112014024256A8 BR112014024256A8 BR112014024256A BR112014024256A BR112014024256A8 BR 112014024256 A8 BR112014024256 A8 BR 112014024256A8 BR 112014024256 A BR112014024256 A BR 112014024256A BR 112014024256 A BR112014024256 A BR 112014024256A BR 112014024256 A8 BR112014024256 A8 BR 112014024256A8
- Authority
- BR
- Brazil
- Prior art keywords
- biorelevant
- aqueous
- medium
- composition
- homogeneous
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 2
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 2
- 229930195729 fatty acid Natural products 0.000 abstract 2
- 239000000194 fatty acid Substances 0.000 abstract 2
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 abstract 2
- 241000282472 Canis lupus familiaris Species 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- BCKXLBQYZLBQEK-KVVVOXFISA-M Sodium oleate Chemical compound [Na+].CCCCCCCC\C=C/CCCCCCCC([O-])=O BCKXLBQYZLBQEK-KVVVOXFISA-M 0.000 abstract 1
- 239000003833 bile salt Substances 0.000 abstract 1
- -1 fatty acid salt Chemical class 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
- 210000000813 small intestine Anatomy 0.000 abstract 1
- JAJWGJBVLPIOOH-IZYKLYLVSA-M sodium taurocholate Chemical compound [Na+].C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCCS([O-])(=O)=O)C)[C@@]2(C)[C@@H](O)C1 JAJWGJBVLPIOOH-IZYKLYLVSA-M 0.000 abstract 1
- 229940045946 sodium taurodeoxycholate Drugs 0.000 abstract 1
- YXHRQQJFKOHLAP-FVCKGWAHSA-M sodium;2-[[(4r)-4-[(3r,5r,8r,9s,10s,12s,13r,14s,17r)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonate Chemical compound [Na+].C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCCS([O-])(=O)=O)C)[C@@]2(C)[C@@H](O)C1 YXHRQQJFKOHLAP-FVCKGWAHSA-M 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
- G09B23/30—Anatomical models
- G09B23/303—Anatomical models specially adapted to simulate circulation of bodily fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
-
- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
- G09B23/30—Anatomical models
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Computational Mathematics (AREA)
- Educational Administration (AREA)
- Mathematical Analysis (AREA)
- Business, Economics & Management (AREA)
- Algebra (AREA)
- Pure & Applied Mathematics (AREA)
- Mathematical Optimization (AREA)
- Mathematical Physics (AREA)
- Educational Technology (AREA)
- Theoretical Computer Science (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12162548.7A EP2645099A1 (en) | 2012-03-30 | 2012-03-30 | Biorelevant compositions |
| PCT/EP2013/056945 WO2013144374A1 (en) | 2012-03-30 | 2013-04-02 | Biorelevant compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112014024256A2 BR112014024256A2 (https=) | 2017-06-20 |
| BR112014024256A8 true BR112014024256A8 (pt) | 2018-02-06 |
Family
ID=48143258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014024256A BR112014024256A8 (pt) | 2012-03-30 | 2013-04-02 | Composição biorrelevante homogênea, meio biorrelevante aquoso, métodos de preparar um meio biorrelevante aquoso e uma composição homogênea, e, uso do meio biorrelevante aquoso |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20150064794A1 (https=) |
| EP (2) | EP2645099A1 (https=) |
| JP (1) | JP6348480B2 (https=) |
| KR (1) | KR20140144255A (https=) |
| CN (1) | CN104582689A (https=) |
| BR (1) | BR112014024256A8 (https=) |
| CA (1) | CA2867638A1 (https=) |
| IN (1) | IN2014DN07927A (https=) |
| MX (1) | MX357927B (https=) |
| NZ (1) | NZ700064A (https=) |
| WO (1) | WO2013144374A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011375432B2 (en) * | 2011-08-23 | 2016-02-04 | Kythera Biopharmaceuticals, Inc. | Formulations of deoxycholic acid and salts thereof |
| WO2019199238A1 (en) * | 2018-04-09 | 2019-10-17 | Vet Products Research And Innovation Center Company Limited | Inorganic mineral entrapped in nanoparticle production method thereof |
| GB201809627D0 (en) * | 2018-06-12 | 2018-07-25 | Biorelevant Com Ltd | Methods for preparing buffer solutions suitable for in vitro drug dissolution testing, drug solubility testing and/or drug profiling |
| GB201904757D0 (en) * | 2019-04-04 | 2019-05-22 | Biorelevant Com Ltd | Biorelevant composition |
| US20220373446A1 (en) * | 2019-06-28 | 2022-11-24 | Janssen Pharmaceutica Nv | Biorelevant dissolution media |
| US20230100584A1 (en) | 2020-02-19 | 2023-03-30 | Bayer Aktiengesellschaft | Predicting formulation properties |
| GB202112975D0 (en) | 2021-09-10 | 2021-10-27 | Biorelevant Com Ltd | Biorelevant dissolution compositions with reproducible spectral profiles |
| GB202405714D0 (en) * | 2024-04-23 | 2024-06-05 | Biorelevant Com Ltd | Biorelevant compositions and media for in vitro testing |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4874795A (en) * | 1985-04-02 | 1989-10-17 | Yesair David W | Composition for delivery of orally administered drugs and other substances |
| GB8909022D0 (en) * | 1989-04-20 | 1989-06-07 | Cortecs Ltd | Pharmaceutical compositions |
| US6040188A (en) * | 1997-11-18 | 2000-03-21 | The Regents Of The University Of California | In vitro gastrointestinal mimetic protocol for measuring bioavailable contaminants |
| IT1296914B1 (it) * | 1997-12-01 | 1999-08-03 | Maria Rosa Gasco | Composizione farmaceutica comprendente microparticelle atte al passaggio transmucosale ed al superamento della barriera |
| WO2003042392A1 (en) * | 2001-11-15 | 2003-05-22 | Phares Pharmaceutical Research N.V. | Standardised phospholipid mixtures |
| EP1734937A1 (en) * | 2004-03-26 | 2006-12-27 | Cell Therapeutics Europe S.R.L. | Nanoparticle formulations of platinum compounds |
| GB0522942D0 (en) | 2005-11-10 | 2005-12-21 | Leigh Steven | Dissolution composition |
| PL1981516T3 (pl) * | 2006-01-27 | 2019-03-29 | Dupont Nutrition Biosciences Aps | Zastosowanie mikroorganizmów probiotycznych w leczeniu i zapobieganiu otyłości i pokrewnym zaburzeniom |
| WO2008040799A2 (en) | 2006-10-06 | 2008-04-10 | Boehringer Ingelheim International Gmbh | Process for preparing instant forms of aqueous mixed micellar solutions as physiological buffer systems for use in the analysis of in vitro release |
-
2012
- 2012-03-30 EP EP12162548.7A patent/EP2645099A1/en not_active Ceased
-
2013
- 2013-04-02 MX MX2014011789A patent/MX357927B/es active IP Right Grant
- 2013-04-02 CA CA2867638A patent/CA2867638A1/en not_active Abandoned
- 2013-04-02 WO PCT/EP2013/056945 patent/WO2013144374A1/en not_active Ceased
- 2013-04-02 BR BR112014024256A patent/BR112014024256A8/pt not_active Application Discontinuation
- 2013-04-02 NZ NZ700064A patent/NZ700064A/en not_active IP Right Cessation
- 2013-04-02 KR KR1020147030491A patent/KR20140144255A/ko not_active Ceased
- 2013-04-02 IN IN7927DEN2014 patent/IN2014DN07927A/en unknown
- 2013-04-02 EP EP13717734.1A patent/EP2830592A1/en not_active Withdrawn
- 2013-04-02 CN CN201380018498.8A patent/CN104582689A/zh active Pending
- 2013-04-02 JP JP2015502383A patent/JP6348480B2/ja not_active Expired - Fee Related
- 2013-04-02 US US14/389,701 patent/US20150064794A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013144374A1 (en) | 2013-10-03 |
| US20150064794A1 (en) | 2015-03-05 |
| JP2015524913A (ja) | 2015-08-27 |
| JP6348480B2 (ja) | 2018-06-27 |
| MX357927B (es) | 2018-07-27 |
| BR112014024256A2 (https=) | 2017-06-20 |
| KR20140144255A (ko) | 2014-12-18 |
| CN104582689A (zh) | 2015-04-29 |
| NZ700064A (en) | 2016-08-26 |
| IN2014DN07927A (https=) | 2015-05-01 |
| CA2867638A1 (en) | 2013-10-03 |
| EP2830592A1 (en) | 2015-02-04 |
| EP2645099A1 (en) | 2013-10-02 |
| MX2014011789A (es) | 2015-06-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B25A | Requested transfer of rights approved |
Owner name: BIORELEVANT.COM LTD (GB) |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |