BR112014014652A8 - modified microorganisms and methods of making butadiene using the same - Google Patents

modified microorganisms and methods of making butadiene using the same

Info

Publication number
BR112014014652A8
BR112014014652A8 BR112014014652A BR112014014652A BR112014014652A8 BR 112014014652 A8 BR112014014652 A8 BR 112014014652A8 BR 112014014652 A BR112014014652 A BR 112014014652A BR 112014014652 A BR112014014652 A BR 112014014652A BR 112014014652 A8 BR112014014652 A8 BR 112014014652A8
Authority
BR
Brazil
Prior art keywords
methods
butadiene
same
microorganisms
modified microorganisms
Prior art date
Application number
BR112014014652A
Other languages
Portuguese (pt)
Other versions
BR112014014652B1 (en
BR112014014652A2 (en
Inventor
Michael Slovic Avram
Estrada Gouvea Iuri
Rincones Perez Johana
Penderson Parizzi Lucas
Schreiner Garcez Lopes Mateus
Original Assignee
Braskem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Braskem Sa filed Critical Braskem Sa
Publication of BR112014014652A8 publication Critical patent/BR112014014652A8/en
Publication of BR112014014652A2 publication Critical patent/BR112014014652A2/en
Publication of BR112014014652B1 publication Critical patent/BR112014014652B1/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01127—Linalool dehydratase (4.2.1.127)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

resumo “microrganismos modificados e métodos de fazer butadieno usando os mesmos” a presente invenção refere-se genericamente a microrganismos que compreendem um ou mais polinucleotideos que codificam para as enzimas em uma ou mais vias, que catalisam a conversão de uma fonte de carbono fermentável em butadieno. são também proporcionados métodos de utilização dos microrganismos em processos industriais, incluindo para utilização na produção de butadieno e produtos deles derivados.summary modified microorganisms and methods of making butadiene using the same the present invention refers generally to microorganisms that comprise one or more polynucleotides encoding enzymes in one or more pathways, which catalyze the conversion of a fermentable carbon source into butadiene. Methods of using the microorganisms in industrial processes are also provided, including for use in the production of butadiene and products derived therefrom.

BR112014014652-7A 2011-12-16 2012-12-17 METHOD OF PRODUCTION OF BUTADIENE AND GENETICALLY MODIFIED MICRO-ORGANISM BR112014014652B1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161576788P 2011-12-16 2011-12-16
US61/576,788 2011-12-16
US201261606035P 2012-03-02 2012-03-02
US61/606,035 2012-03-02
PCT/US2012/070161 WO2013090915A1 (en) 2011-12-16 2012-12-17 Modified microorganisms and methods of making butadiene using same

Publications (3)

Publication Number Publication Date
BR112014014652A8 true BR112014014652A8 (en) 2017-06-13
BR112014014652A2 BR112014014652A2 (en) 2017-06-13
BR112014014652B1 BR112014014652B1 (en) 2021-07-13

Family

ID=48613275

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014014652-7A BR112014014652B1 (en) 2011-12-16 2012-12-17 METHOD OF PRODUCTION OF BUTADIENE AND GENETICALLY MODIFIED MICRO-ORGANISM

Country Status (14)

Country Link
US (3) US9518273B2 (en)
EP (1) EP2791342B1 (en)
JP (2) JP6415326B2 (en)
KR (1) KR20150068925A (en)
CN (2) CN104471068A (en)
AU (1) AU2012353654B2 (en)
BR (1) BR112014014652B1 (en)
CA (1) CA2859556C (en)
EC (1) ECSP14007092A (en)
MX (1) MX349910B (en)
PH (1) PH12014501364A1 (en)
RU (1) RU2639564C2 (en)
SG (1) SG11201403276TA (en)
WO (1) WO2013090915A1 (en)

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JP5997939B2 (en) * 2012-05-31 2016-09-28 株式会社ブリヂストン Process for producing conjugated diene polymer
JP5997938B2 (en) * 2012-05-31 2016-09-28 株式会社ブリヂストン Method for producing butadiene polymer and method for producing tire
CN104520431A (en) * 2012-06-18 2015-04-15 布拉斯科南美公司 Modified microorganisms and methods of co-producing butadiene with 1-propanol and/or 1,2-propanediol
EP2925871A1 (en) 2012-11-28 2015-10-07 Invista Technologies S.A R.L. Methods for biosynthesis of isobutene
US20140206066A1 (en) * 2013-01-18 2014-07-24 Coskata, Inc. Syntrophic co-culture of anaerobic microorganism for production of n-butanol from syngas
BR112015020904A2 (en) * 2013-03-15 2017-10-10 Genomatica Inc microorganisms and methods for the production of butadiene and related compounds by formate assimilation
US20150050708A1 (en) * 2013-03-15 2015-02-19 Genomatica, Inc. Microorganisms and methods for producing butadiene and related compounds by formate assimilation
US10294496B2 (en) 2013-07-19 2019-05-21 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
US9862973B2 (en) 2013-08-05 2018-01-09 Invista North America S.A.R.L. Methods for biosynthesis of isoprene
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WO2015035244A1 (en) * 2013-09-05 2015-03-12 Braskem S/A Modified microorganism and methods of using same for producing butadiene and 1-propanol and/or 1,2-propanediol
EP3536799A3 (en) * 2013-09-23 2020-12-09 Braskem S.A. Engineered enzyme having acetoacetyl-coa hydrolase activity, microorganisms comprising same, and methods of using same
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EP3167066A4 (en) * 2014-07-11 2018-03-07 Genomatica, Inc. Microorganisms and methods for the production of butadiene using acetyl-coa
WO2016097293A1 (en) * 2014-12-19 2016-06-23 Global Bioenergies Process for the enzymatic production of 1-butene from 2-pentenoyl-coa
BR112017018257A2 (en) 2015-02-27 2018-04-10 White Dog Labs Inc mixotropic fermentation method to produce acetone, isopropanol, butyric acid and other bioproducts, and mixtures thereof
BR112017021667A2 (en) * 2015-04-09 2018-07-24 Genomatica Inc modified microorganisms & methods for improved crotyl alcohol production
BR112017025554B1 (en) 2015-05-30 2024-03-12 Genomatica, Inc. COMPOSITION, AND, METHOD FOR PRODUCING A POLYMER, RESIN OR ARTICLE OF MANUFACTURING
CN107922937B (en) * 2015-08-03 2022-03-15 国立研究开发法人理化学研究所 Mevalonate diphosphate decarboxylase variant and process for producing olefin compound using the same
WO2017035141A2 (en) * 2015-08-24 2017-03-02 White Dog Labs, Inc. Microbial organisms for converting acetyl-coa into crotyl alcohol and methods for producing crotyl alcohol
BR112019000633A2 (en) 2016-07-12 2019-07-09 Braskem Sa formation of alkenes through enzymatic dehydration of alkanols
KR101929631B1 (en) 2016-12-20 2018-12-14 서강대학교산학협력단 Method for manufacturing 1,3-butadien using microbial fermentation
US11162115B2 (en) 2017-06-30 2021-11-02 Inv Nylon Chemicals Americas, Llc Methods, synthetic hosts and reagents for the biosynthesis of hydrocarbons
US11634733B2 (en) 2017-06-30 2023-04-25 Inv Nylon Chemicals Americas, Llc Methods, materials, synthetic hosts and reagents for the biosynthesis of hydrocarbons and derivatives thereof
US11505809B2 (en) 2017-09-28 2022-11-22 Inv Nylon Chemicals Americas Llc Organisms and biosynthetic processes for hydrocarbon synthesis
CN108690851B (en) * 2018-05-30 2020-11-06 青岛农业大学 Butadiene producing strain and method for producing butadiene by using same
CN108949788B (en) * 2018-07-10 2020-07-14 广东省微生物研究所（广东省微生物分析检测中心） Lycopene synthesis related gene and application thereof
CN109666683B (en) * 2019-02-27 2021-10-29 昆明理工大学 Acetyl coenzyme A acetyltransferase gene RKAcaT2 and application thereof
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Also Published As

Publication number Publication date
CA2859556A1 (en) 2013-06-20
US9518273B2 (en) 2016-12-13
SG11201403276TA (en) 2014-10-30
PH12014501364A1 (en) 2014-09-22
JP6415326B2 (en) 2018-10-31
KR20150068925A (en) 2015-06-22
AU2012353654A1 (en) 2014-07-10
EP2791342A1 (en) 2014-10-22
JP2015501659A (en) 2015-01-19
CA2859556C (en) 2022-01-11
RU2014129026A (en) 2016-02-10
BR112014014652B1 (en) 2021-07-13
MX349910B (en) 2017-08-17
CN112877370A (en) 2021-06-01
US10059963B2 (en) 2018-08-28
MX2014007235A (en) 2015-04-13
ECSP14007092A (en) 2015-06-30
RU2639564C2 (en) 2017-12-21
CN104471068A (en) 2015-03-25
EP2791342A4 (en) 2016-04-13
AU2012353654A8 (en) 2014-07-17
AU2012353654B2 (en) 2016-09-29
US20160032325A1 (en) 2016-02-04
BR112014014652A2 (en) 2017-06-13
WO2013090915A1 (en) 2013-06-20
US20180346936A1 (en) 2018-12-06
US20140370564A1 (en) 2014-12-18
US10273505B2 (en) 2019-04-30
EP2791342B1 (en) 2020-04-29
JP2018134113A (en) 2018-08-30
US20150152439A2 (en) 2015-06-04

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 17/12/2012, OBSERVADAS AS CONDICOES LEGAIS.