BR112014007676A2 - isolated renal stem cells from kidney - Google Patents

isolated renal stem cells from kidney

Info

Publication number
BR112014007676A2
BR112014007676A2 BR112014007676A BR112014007676A BR112014007676A2 BR 112014007676 A2 BR112014007676 A2 BR 112014007676A2 BR 112014007676 A BR112014007676 A BR 112014007676A BR 112014007676 A BR112014007676 A BR 112014007676A BR 112014007676 A2 BR112014007676 A2 BR 112014007676A2
Authority
BR
Brazil
Prior art keywords
cell
kidney
renal
stem cells
multipotent
Prior art date
Application number
BR112014007676A
Other languages
Portuguese (pt)
Inventor
B Rangel Erika
M Hare Joshua
A Gomes Samirah
Original Assignee
The Univ Of Miami
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Univ Of Miami filed Critical The Univ Of Miami
Publication of BR112014007676A2 publication Critical patent/BR112014007676A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0684—Cells of the urinary tract or kidneys
    • C12N5/0687—Renal stem cells; Renal progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/22—Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution

Abstract

abstract of the disclosure a novel renal precursor cell is identified from kidney tissue. the cell is multipotent capable of forming renal epithelial and endothelial tissues. the cell can be amplified in culture and maintains stemness over multiple passages. this cell fulfills a major unmet need as a cell-based source for kidney regeneration or repair. treatment of kidney diseases and disorders (e.g., glomerularpathies and acute tubular necrosis) may be improved thereby. tradução do resumo resumo patente de invenção: "células-tronco renais isoladas do rim". uma nova célula precursora renal é identificada a partir de tecido de rim. a célula é multipotente capaz de formar tecidos epiteliais e endoteliais renais. a célula pode ser amplificada em cultura e mantém suas características após várias passagens. esta célula cumpre a maior parte da necessidade não atendida como uma fonte baseada em células de regeneração ou reparo renal. tratamento de doenças e distúrbios renais (por exemplo, glomerulopatias e necrose tubular aguda) pode ser melhorado desta forma.abstract of the disclosure a novel renal cell precursor is identified from kidney tissue. the cell is multipotent capable of forming renal epithelial and endothelial tissues. the cell can be amplified in culture and maintains stemness over multiple passages. this cell fulfills a major unmet need as a cell-based source for kidney regeneration or repair. treatment of kidney diseases and disorders (e.g., glomerular diseases and acute tubular necrosis) may be improved thereby. abstract of patent summary: "kidney stem cells isolated from the kidney". A new renal precursor cell is identified from kidney tissue. The cell is multipotent capable of forming renal epithelial and endothelial tissues. The cell can be amplified in culture and retains its characteristics after several passages. This cell fulfills most of the unmet need as a cell-based source for regeneration or renal repair. Treatment of kidney disease and disorders (eg, glomerulopathies and acute tubular necrosis) can be improved in this way.

BR112014007676A 2011-09-30 2012-10-01 isolated renal stem cells from kidney BR112014007676A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161541680P 2011-09-30 2011-09-30
PCT/US2012/058369 WO2013049856A2 (en) 2011-09-30 2012-10-01 Renal stem cells isolated from kidney

Publications (1)

Publication Number Publication Date
BR112014007676A2 true BR112014007676A2 (en) 2017-04-18

Family

ID=47996798

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014007676A BR112014007676A2 (en) 2011-09-30 2012-10-01 isolated renal stem cells from kidney

Country Status (4)

Country Link
US (1) US20140271578A1 (en)
EP (1) EP2760995B1 (en)
BR (1) BR112014007676A2 (en)
WO (1) WO2013049856A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3567099T3 (en) * 2012-10-24 2021-11-29 Prokidney Renal cell populations and uses thereof
WO2023217126A1 (en) * 2022-05-10 2023-11-16 上海赛立维生物科技有限公司 Renal epithelial precursor-like cell, and preparation method therefor, preparation thereof and use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4690915A (en) 1985-08-08 1987-09-01 The United States Of America As Represented By The Department Of Health And Human Services Adoptive immunotherapy as a treatment modality in humans
US4844893A (en) 1986-10-07 1989-07-04 Scripps Clinic And Research Foundation EX vivo effector cell activation for target cell killing
US5843780A (en) 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
US20020142457A1 (en) * 1999-12-28 2002-10-03 Akihiro Umezawa Cell having the potentiality of differentiation into cardiomyocytes
US20110091428A1 (en) * 2000-07-31 2011-04-21 New York Medical College Compositions of adult organ stem cells and uses thereof
EP2186883A1 (en) * 2008-11-04 2010-05-19 Fresenius Medical Care An isolated multipotent mesenchymal stem cell from human adult glomeruli (hGL-MSC), a method of preparing thereof and uses thereof in the regenerative medicine of the kidney

Also Published As

Publication number Publication date
WO2013049856A8 (en) 2013-06-27
WO2013049856A3 (en) 2013-08-15
WO2013049856A9 (en) 2013-05-02
WO2013049856A2 (en) 2013-04-04
US20140271578A1 (en) 2014-09-18
EP2760995B1 (en) 2019-08-07
EP2760995A4 (en) 2015-03-11
EP2760995A2 (en) 2014-08-06

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]