BR112013006689A2 - manufacture of tablets from energy applied powder blends - Google Patents

manufacture of tablets from energy applied powder blends

Info

Publication number
BR112013006689A2
BR112013006689A2 BR112013006689A BR112013006689A BR112013006689A2 BR 112013006689 A2 BR112013006689 A2 BR 112013006689A2 BR 112013006689 A BR112013006689 A BR 112013006689A BR 112013006689 A BR112013006689 A BR 112013006689A BR 112013006689 A2 BR112013006689 A2 BR 112013006689A2
Authority
BR
Brazil
Prior art keywords
tablets
manufacture
energy applied
powder blends
binders
Prior art date
Application number
BR112013006689A
Other languages
Portuguese (pt)
Inventor
Christopher E Szymczak
Frank J Bunick
Harry S Sowden
Joseph R Luber
Leo B Kriksunov
Original Assignee
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/887,552 external-priority patent/US9610224B2/en
Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc
Priority claimed from US13/052,200 external-priority patent/US20110319492A1/en
Publication of BR112013006689A2 publication Critical patent/BR112013006689A2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/027—Particular press methods or systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/34—Heating or cooling presses or parts thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)

Abstract

fabricação de tabletes a partir de blenda de pós com energia aplicada. a presente invenção refere-se a um processo para produção de tabletes contendo um ou mais agentes farmaceuticamente ativos e um ou mais aglutinantes, sendo que o método inclui as etapas de: (i) aplicar energia a uma blenda de pós compreendendo os um ou mais agentes farmaceuticamente ativos e os um ou mais aglutinantes durante um período de tempo suficiente para ativar os um ou mais aglutinantes contidos na blenda de pós e (ii) usar uma quantidade predeterminada da blenda de pós com energia aplicada para formar os tabletes.manufacture of tablets from powder blends with applied energy. The present invention relates to a process for producing tablets containing one or more pharmaceutically active agents and one or more binders, the method comprising the steps of: (i) applying energy to a powder blend comprising one or more pharmaceutically active agents and the one or more binders for a period of time sufficient to activate the one or more binders contained in the powder blend and (ii) use a predetermined amount of the energy applied powder blend to form the tablets.

BR112013006689A 2010-09-22 2011-03-21 manufacture of tablets from energy applied powder blends BR112013006689A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12/887,552 US9610224B2 (en) 2009-09-24 2010-09-22 Manufacture of tablet in a die utilizing powder blend containing water-containing material
US12/887,544 US8871263B2 (en) 2009-09-24 2010-09-22 Manufacture of tablet in a die utilizing radiofrequency energy and meltable binder
US13/052,200 US20110319492A1 (en) 2010-06-24 2011-03-21 Manufacture of tablets from energy-applied powder blend
PCT/US2011/029161 WO2012039790A1 (en) 2010-09-22 2011-03-21 Manufacture of tablets from energy-applied powder blend

Publications (1)

Publication Number Publication Date
BR112013006689A2 true BR112013006689A2 (en) 2016-06-07

Family

ID=44140931

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013006689A BR112013006689A2 (en) 2010-09-22 2011-03-21 manufacture of tablets from energy applied powder blends

Country Status (9)

Country Link
EP (1) EP2618813A1 (en)
KR (1) KR20130106399A (en)
CN (1) CN103124552A (en)
AU (1) AU2011306065B2 (en)
BR (1) BR112013006689A2 (en)
CA (1) CA2810837A1 (en)
MX (1) MX2013003288A (en)
RU (1) RU2013118252A (en)
WO (1) WO2012039790A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015105992A1 (en) * 2014-01-10 2015-07-16 Mcneil-Ppc, Inc. Process for making tablet using radiofrequency and lossy coated particles
EP3544585A1 (en) * 2016-11-28 2019-10-02 Johnson & Johnson Consumer Inc. Process for making a coated dosage form
US10493026B2 (en) * 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268465A (en) * 1978-01-27 1981-05-19 Massachusetts Institute Of Technology Method of accelerating the cooling of polymeric articles
JPS5967006A (en) * 1982-10-08 1984-04-16 Hitachi Ltd Tablet forming machine
US4851226A (en) 1987-11-16 1989-07-25 Mcneil Consumer Products Company Chewable medicament tablet containing means for taste masking
US4906478A (en) 1988-12-12 1990-03-06 Valentine Enterprises, Inc. Simethicone/calcium silicate composition
EP0416791A2 (en) * 1989-09-08 1991-03-13 General Motors Corporation Method and apparatus for compression moulding with dielectric heating
US5223264A (en) 1989-10-02 1993-06-29 Cima Labs, Inc. Pediatric effervescent dosage form
US5178878A (en) 1989-10-02 1993-01-12 Cima Labs, Inc. Effervescent dosage form with microparticles
US5275822A (en) 1989-10-19 1994-01-04 Valentine Enterprises, Inc. Defoaming composition
US5075114A (en) 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
CA2068402C (en) 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
US5464632C1 (en) 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
DE19531277A1 (en) 1995-08-25 1997-02-27 Basf Ag Use of lipids as an aid in the production of solid dosage forms by the melt extrusion process
EP0893992B1 (en) * 1996-04-16 2004-03-03 Novartis Consumer Health S.A. Fast disintegrating oral dosage form
CA2257303C (en) 1996-06-17 2006-04-04 Janssen Pharmaceutica N.V. Biconvex rapidly disintegrating dosage forms
US5939091A (en) * 1997-05-20 1999-08-17 Warner Lambert Company Method for making fast-melt tablets
US6103260A (en) 1997-07-17 2000-08-15 Mcneil-Ppc, Inc. Simethicone/anhydrous calcium phosphate compositions
US6589554B1 (en) 1998-03-16 2003-07-08 Yamanouchi Pharmaceutical Co., Ltd. Tablets quickly disintegrating in the oral cavity and process for producing the same
DE19812688A1 (en) 1998-03-23 1999-09-30 Basf Ag Solid dosage forms useful for slow release of drugs, fragrances, plant-treating agents, animal feed additives and food additives
US6767200B2 (en) 2001-09-28 2004-07-27 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US7807197B2 (en) 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
CA2524806C (en) * 2003-05-07 2011-07-12 Akina, Inc. Highly plastic granules for making fast melting tablets
US20090060983A1 (en) * 2007-08-30 2009-03-05 Bunick Frank J Method And Composition For Making An Orally Disintegrating Dosage Form

Also Published As

Publication number Publication date
AU2011306065A1 (en) 2013-02-28
EP2618813A1 (en) 2013-07-31
WO2012039790A1 (en) 2012-03-29
AU2011306065B2 (en) 2015-03-19
KR20130106399A (en) 2013-09-27
MX2013003288A (en) 2013-05-22
CN103124552A (en) 2013-05-29
CA2810837A1 (en) 2012-03-29
RU2013118252A (en) 2014-10-27

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]