BR112013006410B1 - Dispositivo de aplicaqao de dose - Google Patents
Dispositivo de aplicaqao de dose Download PDFInfo
- Publication number
- BR112013006410B1 BR112013006410B1 BR112013006410-2A BR112013006410A BR112013006410B1 BR 112013006410 B1 BR112013006410 B1 BR 112013006410B1 BR 112013006410 A BR112013006410 A BR 112013006410A BR 112013006410 B1 BR112013006410 B1 BR 112013006410B1
- Authority
- BR
- Brazil
- Prior art keywords
- dose
- impeller
- transmission member
- selector
- transmission
- Prior art date
Links
- 230000005540 biological transmission Effects 0.000 claims abstract description 133
- 238000002347 injection Methods 0.000 abstract description 35
- 239000007924 injection Substances 0.000 abstract description 35
- 239000003814 drug Substances 0.000 abstract description 13
- 230000008878 coupling Effects 0.000 description 20
- 238000010168 coupling process Methods 0.000 description 20
- 238000005859 coupling reaction Methods 0.000 description 20
- 229940079593 drug Drugs 0.000 description 9
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- 230000002457 bidirectional effect Effects 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000005570 vertical transmission Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
- A61M5/31528—Dosing by means of rotational movements, e.g. screw-thread mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
- A61M5/31526—Dosing by means of stepwise axial movements, e.g. ratchet mechanisms or detents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31556—Accuracy improving means
- A61M5/31558—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
- A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201000872 | 2010-09-24 | ||
| DKPA201000872 | 2010-09-24 | ||
| PCT/DK2011/000103 WO2012037938A1 (en) | 2010-09-24 | 2011-09-23 | A gearing mechanism for a dose delivery device |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR112013006410A2 BR112013006410A2 (pt) | 2016-07-26 |
| BR112013006410A8 BR112013006410A8 (pt) | 2020-11-03 |
| BR112013006410B1 true BR112013006410B1 (pt) | 2020-11-17 |
Family
ID=44883028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013006410-2A BR112013006410B1 (pt) | 2010-09-24 | 2011-09-23 | Dispositivo de aplicaqao de dose |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8864721B2 (https=) |
| EP (1) | EP2618872B1 (https=) |
| JP (1) | JP5903102B2 (https=) |
| KR (1) | KR101493626B1 (https=) |
| CN (1) | CN103189084B (https=) |
| AU (1) | AU2011304788B2 (https=) |
| BR (1) | BR112013006410B1 (https=) |
| CA (1) | CA2813007C (https=) |
| DK (1) | DK2618872T3 (https=) |
| EA (1) | EA024223B1 (https=) |
| MX (1) | MX2013003340A (https=) |
| PL (1) | PL2618872T3 (https=) |
| UA (1) | UA109665C2 (https=) |
| WO (1) | WO2012037938A1 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120283652A1 (en) * | 2009-09-30 | 2012-11-08 | Sanofi-Aventis Deutschland Gmbh | Assembly and Piston Rod for a Drug Delivery Device |
| JP6057991B2 (ja) * | 2011-06-17 | 2017-01-11 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 薬物送達デバイス用カートリッジ・ホルダ・アセンブリ |
| USD737432S1 (en) * | 2011-06-27 | 2015-08-25 | Ferring B.V. | Medicine applicator |
| EP2644217A1 (de) | 2012-03-30 | 2013-10-02 | TecPharma Licensing AG | Injektionsvorrichtung mit Dosisanzeige und Federantrieb |
| EP2830685B1 (de) | 2012-03-30 | 2017-05-31 | Tecpharma Licensing AG | Injektionsvorrichtung mit einem relativ zu einem gehäuse verschiebbaren dosisanzeigeelement |
| EP2644218B2 (de) | 2012-03-30 | 2022-11-02 | Tecpharma Licensing AG | Injektionsvorrichtung mit Dosisanzeige und Federantrieb |
| AU349334S (en) * | 2012-07-05 | 2013-06-20 | Sanofi Aventis Deutschland | Injection device |
| DK2911722T3 (da) * | 2012-10-23 | 2021-08-23 | Sanofi Aventis Deutschland | Tællersystem til brug i en anordning til indgivelse af lægemidler |
| JP6307528B2 (ja) * | 2013-03-14 | 2018-04-04 | ノートン・ヘルスケア・リミテッド | 医療器具のための投薬機構 |
| MX2015012901A (es) | 2013-03-14 | 2016-04-04 | Norton Healthcare Ltd | Mecanismo de dispensacion para un dispositivo medico. |
| EP2968787B1 (en) * | 2013-03-14 | 2020-04-29 | Norton Healthcare Limited | Dispensing mechanism for a medical device |
| GB2511806A (en) | 2013-03-14 | 2014-09-17 | Norton Healthcare Ltd | Dispensing mechanism for a medical device |
| US10322242B2 (en) * | 2013-09-03 | 2019-06-18 | Sanofi | Mechanism for a drug delivery device and drug delivery device comprising the mechanism |
| GB201318817D0 (en) * | 2013-10-24 | 2013-12-11 | Owen Mumford Ltd | Injection Devices |
| US10842945B2 (en) * | 2013-11-22 | 2020-11-24 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device with unidirectional coupling |
| AU2015269605A1 (en) | 2014-06-06 | 2016-10-27 | Eli Lilly And Company | Rotatable end of dose feedback mechanism |
| USD777907S1 (en) * | 2014-08-27 | 2017-01-31 | Merck Sharp & Dohme Corp. | Medical injector pen |
| USD773646S1 (en) * | 2014-08-27 | 2016-12-06 | Merck Sharp & Dohme Corp | Medical injector pen |
| USD752210S1 (en) * | 2014-08-27 | 2016-03-22 | Merck Sharp & Dohme Corp. | Medical injector pen |
| WO2016114985A1 (en) | 2015-01-16 | 2016-07-21 | Eli Lilly And Company | Injection device with end of dose mechanism |
| US10485927B2 (en) | 2015-07-01 | 2019-11-26 | Novo Nordisk A/S | Method for assembling a drug delivery device and drug delivery device formed by the method |
| USD850613S1 (en) * | 2016-09-09 | 2019-06-04 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device |
| CN107648704B (zh) * | 2016-07-26 | 2022-02-15 | 广东东阳光药业有限公司 | 一种注射器用传动结构及注射器 |
| DE102018108701A1 (de) * | 2018-04-12 | 2019-10-17 | Gerhard Brugger | System mit einem Dosierspender für das Austragen von pastösem oder viskosem Material |
| US12121707B2 (en) | 2018-09-08 | 2024-10-22 | Shaily Engineering Plastics Limited | Injection device |
| CN109078240B (zh) * | 2018-09-30 | 2024-05-14 | 江苏德尔福医疗器械有限公司 | 带有剂量反馈装置的一次性注射笔 |
| RU2729442C1 (ru) * | 2019-10-23 | 2020-08-06 | Общество с ограниченной ответственностью "НЭКСТ БИО" | Устройство для доставки лекарственного средства |
| GB2604096B (en) * | 2021-02-09 | 2023-03-15 | Shaily Uk Ltd | Dose delivery device with gearing |
| CN118804777A (zh) | 2022-01-14 | 2024-10-18 | 辉美医疗器械有限公司 | 带有修改的将离合器结合解除的剂量输送装置 |
| PL444242A1 (pl) * | 2023-03-28 | 2024-09-30 | Nemera Szczecin Spółka Z Ograniczoną Odpowiedzialnością | Urządzenie do wstrzykiwania leku |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3645245C2 (de) | 1986-11-14 | 1994-01-27 | Haselmeier Wilhelm Fa | Injektionsgerät |
| DK166948B1 (da) | 1988-02-10 | 1993-08-09 | Dcp Af 1988 As | Doseringsenhed til dosering af et antal afmaalte maengder af en vaeske, saasom insulin, fra en glastubule |
| US5279585A (en) | 1992-02-04 | 1994-01-18 | Becton, Dickinson And Company | Medication delivery pen having improved dose delivery features |
| US5391157A (en) | 1992-10-20 | 1995-02-21 | Eli Lilly And Company | End of dose indicator |
| GB9226423D0 (en) | 1992-12-18 | 1993-02-10 | Sams Bernard | Incrementing mechanisms |
| US5725508A (en) | 1994-06-22 | 1998-03-10 | Becton Dickinson And Company | Quick connect medication delivery pen |
| JP3568959B2 (ja) | 1995-03-07 | 2004-09-22 | イーライ・リリー・アンド・カンパニー | 再利用可能な投薬装置 |
| US5688251A (en) | 1995-09-19 | 1997-11-18 | Becton Dickinson And Company | Cartridge loading and priming mechanism for a pen injector |
| US5921966A (en) | 1997-08-11 | 1999-07-13 | Becton Dickinson And Company | Medication delivery pen having an improved clutch assembly |
| DE69900026T2 (de) | 1998-01-30 | 2001-05-10 | Novo Nordisk As | Eine injektionsspritze |
| US6221053B1 (en) | 1998-02-20 | 2001-04-24 | Becton, Dickinson And Company | Multi-featured medication delivery pen |
| US6663602B2 (en) | 2000-06-16 | 2003-12-16 | Novo Nordisk A/S | Injection device |
| DK2258424T3 (da) | 2001-05-16 | 2013-02-18 | Lilly Co Eli | Indretning til injektion af lægemidler |
| GB0205485D0 (en) | 2002-03-08 | 2002-04-24 | Dca Design Int Ltd | Improvements in and relating to a medicament delivery service |
| US6945961B2 (en) | 2002-07-10 | 2005-09-20 | Novo Nordisk A/S | Injection device |
| DE10237258B4 (de) | 2002-08-14 | 2006-09-21 | Tecpharma Licensing Ag | Injektionsvorrichtung |
| GB0304824D0 (en) | 2003-03-03 | 2003-04-09 | Dca Internat Ltd | Improvements in and relating to a pen-type injector |
| GB0304823D0 (en) | 2003-03-03 | 2003-04-09 | Dca Internat Ltd | Improvements in and relating to a pen-type injector |
| GB0304822D0 (en) | 2003-03-03 | 2003-04-09 | Dca Internat Ltd | Improvements in and relating to a pen-type injector |
| EP2210634A1 (en) | 2009-01-22 | 2010-07-28 | Sanofi-Aventis Deutschland GmbH | Drug delivery device dose setting mechanism |
| AU2004266131C1 (en) | 2003-08-12 | 2010-12-16 | Eli Lilly And Company | Medication dispensing apparatus with triple screw threads for mechanical advantage |
| DE20317377U1 (de) | 2003-11-03 | 2005-03-17 | B D Medico S A R L | Injektionsgerät |
| US20080287883A1 (en) | 2004-12-01 | 2008-11-20 | Novo Nordisk A/S | Injection Device |
| PL1877119T3 (pl) | 2005-01-25 | 2019-03-29 | Novo Nordisk A/S | Urządzenie do wstrzykiwania z mechanizmem zwrotnym informującym o końcu dawki |
| ATE418351T1 (de) | 2005-02-11 | 2009-01-15 | Novo Nordisk As | Injektionsvorrichtung |
| DE102005008280B3 (de) * | 2005-02-23 | 2006-07-13 | Tecpharma Licensing Ag | Verabreichungsvorrichtung mit Anzeigetrommel |
| US20080234633A1 (en) | 2005-07-08 | 2008-09-25 | Novo Nordisk A/S | Injection Device |
| EP1923084A1 (en) | 2006-11-17 | 2008-05-21 | Sanofi-Aventis Deutschland GmbH | Dosing and drive mechanism for drug delivery device |
| US8267901B2 (en) | 2007-09-25 | 2012-09-18 | Claus Schmidt Moller | Dose delivery device with gearing mechanism |
| US8647309B2 (en) | 2008-05-02 | 2014-02-11 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device |
| WO2010072229A1 (de) * | 2008-12-22 | 2010-07-01 | Tecpharma Licensing Ag | Dosiervorrichtung für eine injektionsvorrichtung |
-
2011
- 2011-09-23 EP EP11776068.6A patent/EP2618872B1/en active Active
- 2011-09-23 PL PL11776068T patent/PL2618872T3/pl unknown
- 2011-09-23 JP JP2013529549A patent/JP5903102B2/ja active Active
- 2011-09-23 UA UAA201303085A patent/UA109665C2/uk unknown
- 2011-09-23 DK DK11776068.6T patent/DK2618872T3/da active
- 2011-09-23 CA CA2813007A patent/CA2813007C/en active Active
- 2011-09-23 MX MX2013003340A patent/MX2013003340A/es active IP Right Grant
- 2011-09-23 KR KR20137007285A patent/KR101493626B1/ko active Active
- 2011-09-23 BR BR112013006410-2A patent/BR112013006410B1/pt active IP Right Grant
- 2011-09-23 CN CN201180045735.0A patent/CN103189084B/zh active Active
- 2011-09-23 WO PCT/DK2011/000103 patent/WO2012037938A1/en not_active Ceased
- 2011-09-23 EA EA201390247A patent/EA024223B1/ru not_active IP Right Cessation
- 2011-09-23 US US13/825,396 patent/US8864721B2/en active Active
- 2011-09-23 AU AU2011304788A patent/AU2011304788B2/en active Active
-
2014
- 2014-10-16 US US14/515,551 patent/US20150038916A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DK2618872T3 (da) | 2020-06-02 |
| KR101493626B1 (ko) | 2015-02-13 |
| CA2813007C (en) | 2016-05-17 |
| BR112013006410A8 (pt) | 2020-11-03 |
| EA201390247A1 (ru) | 2013-09-30 |
| EA024223B1 (ru) | 2016-08-31 |
| EP2618872B1 (en) | 2020-04-15 |
| JP2013537819A (ja) | 2013-10-07 |
| CN103189084B (zh) | 2015-03-25 |
| MX2013003340A (es) | 2013-12-02 |
| UA109665C2 (xx) | 2015-09-25 |
| US20150038916A1 (en) | 2015-02-05 |
| CA2813007A1 (en) | 2012-03-29 |
| US20130184653A1 (en) | 2013-07-18 |
| AU2011304788B2 (en) | 2014-09-04 |
| KR20130079510A (ko) | 2013-07-10 |
| AU2011304788A1 (en) | 2013-03-14 |
| EP2618872A1 (en) | 2013-07-31 |
| PL2618872T3 (pl) | 2020-11-16 |
| CN103189084A (zh) | 2013-07-03 |
| JP5903102B2 (ja) | 2016-04-13 |
| US8864721B2 (en) | 2014-10-21 |
| WO2012037938A1 (en) | 2012-03-29 |
| BR112013006410A2 (pt) | 2016-07-26 |
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