BR112013006250B1 - Método e disposição de geração de um gás que compreende oxigênio e óxido nítrico - Google Patents
Método e disposição de geração de um gás que compreende oxigênio e óxido nítrico Download PDFInfo
- Publication number
- BR112013006250B1 BR112013006250B1 BR112013006250-9A BR112013006250A BR112013006250B1 BR 112013006250 B1 BR112013006250 B1 BR 112013006250B1 BR 112013006250 A BR112013006250 A BR 112013006250A BR 112013006250 B1 BR112013006250 B1 BR 112013006250B1
- Authority
- BR
- Brazil
- Prior art keywords
- gas
- oxygen
- membrane
- nitrous oxide
- flow
- Prior art date
Links
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 title claims abstract description 170
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title claims abstract description 165
- 239000001301 oxygen Substances 0.000 title claims abstract description 165
- 229910052760 oxygen Inorganic materials 0.000 title claims abstract description 165
- 238000000034 method Methods 0.000 title claims abstract description 57
- 239000007789 gas Substances 0.000 claims abstract description 328
- GQPLMRYTRLFLPF-UHFFFAOYSA-N Nitrous Oxide Chemical compound [O-][N+]#N GQPLMRYTRLFLPF-UHFFFAOYSA-N 0.000 claims abstract description 292
- 239000012528 membrane Substances 0.000 claims abstract description 244
- 239000001272 nitrous oxide Substances 0.000 claims abstract description 143
- 238000010438 heat treatment Methods 0.000 claims abstract description 33
- 230000008569 process Effects 0.000 claims abstract description 14
- 239000004020 conductor Substances 0.000 claims description 42
- 230000035484 reaction time Effects 0.000 claims description 11
- 238000002156 mixing Methods 0.000 claims description 9
- 238000000926 separation method Methods 0.000 claims description 9
- 108700031620 S-acetylthiorphan Proteins 0.000 claims description 4
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 claims description 2
- 229910017604 nitric acid Inorganic materials 0.000 claims description 2
- 230000002195 synergetic effect Effects 0.000 abstract description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 22
- 230000015572 biosynthetic process Effects 0.000 description 21
- MGWGWNFMUOTEHG-UHFFFAOYSA-N 4-(3,5-dimethylphenyl)-1,3-thiazol-2-amine Chemical compound CC1=CC(C)=CC(C=2N=C(N)SC=2)=C1 MGWGWNFMUOTEHG-UHFFFAOYSA-N 0.000 description 17
- JCXJVPUVTGWSNB-UHFFFAOYSA-N nitrogen dioxide Inorganic materials O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 description 17
- 238000006243 chemical reaction Methods 0.000 description 16
- 230000001225 therapeutic effect Effects 0.000 description 13
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 12
- 229910052757 nitrogen Inorganic materials 0.000 description 12
- 239000000203 mixture Substances 0.000 description 9
- 230000008901 benefit Effects 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- 230000006835 compression Effects 0.000 description 6
- 238000007906 compression Methods 0.000 description 6
- 238000011065 in-situ storage Methods 0.000 description 6
- 239000012159 carrier gas Substances 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 230000004907 flux Effects 0.000 description 5
- 238000003860 storage Methods 0.000 description 5
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 description 4
- 239000000919 ceramic Substances 0.000 description 4
- 238000001816 cooling Methods 0.000 description 4
- 230000001419 dependent effect Effects 0.000 description 4
- 238000009413 insulation Methods 0.000 description 4
- 238000002640 oxygen therapy Methods 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 3
- 239000003054 catalyst Substances 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 206010021143 Hypoxia Diseases 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 239000006227 byproduct Substances 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 239000011261 inert gas Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 239000002243 precursor Substances 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 239000012465 retentate Substances 0.000 description 2
- 238000007086 side reaction Methods 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- WUKWITHWXAAZEY-UHFFFAOYSA-L calcium difluoride Chemical compound [F-].[F-].[Ca+2] WUKWITHWXAAZEY-UHFFFAOYSA-L 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 238000003795 desorption Methods 0.000 description 1
- 230000002542 deteriorative effect Effects 0.000 description 1
- YWEUIGNSBFLMFL-UHFFFAOYSA-N diphosphonate Chemical compound O=P(=O)OP(=O)=O YWEUIGNSBFLMFL-UHFFFAOYSA-N 0.000 description 1
- 239000010436 fluorite Substances 0.000 description 1
- 208000018875 hypoxemia Diseases 0.000 description 1
- 230000007954 hypoxia Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 229910052809 inorganic oxide Inorganic materials 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000011224 oxide ceramic Substances 0.000 description 1
- 229910052574 oxide ceramic Inorganic materials 0.000 description 1
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- DLYUQMMRRRQYAE-UHFFFAOYSA-N phosphorus pentoxide Inorganic materials O1P(O2)(=O)OP3(=O)OP1(=O)OP2(=O)O3 DLYUQMMRRRQYAE-UHFFFAOYSA-N 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 230000000287 tissue oxygenation Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000002341 toxic gas Substances 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B13/00—Oxygen; Ozone; Oxides or hydroxides in general
- C01B13/02—Preparation of oxygen
- C01B13/0229—Purification or separation processes
- C01B13/0248—Physical processing only
- C01B13/0251—Physical processing only by making use of membranes
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B21/00—Nitrogen; Compounds thereof
- C01B21/20—Nitrogen oxides; Oxyacids of nitrogen; Salts thereof
- C01B21/24—Nitric oxide (NO)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/02—Gases
- A61M2202/0266—Nitrogen (N)
- A61M2202/0275—Nitric oxide [NO]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Anesthesiology (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Oxygen, Ozone, And Oxides In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10178293 | 2010-09-22 | ||
| EP10178293.6 | 2010-09-22 | ||
| EP11156845.7 | 2011-03-03 | ||
| EP11156845 | 2011-03-03 | ||
| PCT/IB2011/054018 WO2012038860A1 (en) | 2010-09-22 | 2011-09-14 | Method and arrangement for generating oxygen and nitric oxide. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112013006250A2 BR112013006250A2 (pt) | 2020-06-09 |
| BR112013006250B1 true BR112013006250B1 (pt) | 2021-07-13 |
Family
ID=45873507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013006250-9A BR112013006250B1 (pt) | 2010-09-22 | 2011-09-14 | Método e disposição de geração de um gás que compreende oxigênio e óxido nítrico |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8920539B2 (https=) |
| EP (1) | EP2619131B1 (https=) |
| JP (1) | JP5847181B2 (https=) |
| CN (1) | CN103124689B (https=) |
| BR (1) | BR112013006250B1 (https=) |
| WO (1) | WO2012038860A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8696795B2 (en) * | 2009-12-17 | 2014-04-15 | Koninklijke Philips N.V. | Oxygen separation method and system with a plasma pump and a membrane |
| WO2013171628A1 (en) | 2012-05-16 | 2013-11-21 | Koninklijke Philips N.V. | Oxygen separator and method of generating oxygen |
| CN112867525A (zh) * | 2018-10-25 | 2021-05-28 | 帝人制药株式会社 | 一氧化氮投加装置 |
| JP7004841B2 (ja) * | 2018-10-25 | 2022-01-21 | 帝人ファーマ株式会社 | 一酸化窒素投与装置 |
| FR3093926B1 (fr) * | 2019-03-22 | 2022-10-28 | Air Liquide | Appareil et installation de fourniture d’un mélange gazeux à un patient |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61257940A (ja) * | 1985-05-13 | 1986-11-15 | Asahi Chem Ind Co Ltd | ジカルボン酸の製造法 |
| US5269822A (en) * | 1992-09-01 | 1993-12-14 | Air Products And Chemicals, Inc. | Process for recovering oxygen from gaseous mixtures containing water or carbon dioxide which process employs barium-containing ion transport membranes |
| US5472680A (en) * | 1994-01-26 | 1995-12-05 | E. I. Du Pont De Nemours And Company | Production of NO from N2 O |
| US5954859A (en) * | 1997-11-18 | 1999-09-21 | Praxair Technology, Inc. | Solid electrolyte ionic conductor oxygen production with power generation |
| JP4212234B2 (ja) | 1997-11-18 | 2009-01-21 | 旭化成ケミカルズ株式会社 | 地球温暖化防止方法及びその装置 |
| US6347627B1 (en) | 1998-04-23 | 2002-02-19 | Pioneer Inventions, Inc. | Nitrous oxide based oxygen supply system |
| DE19902109A1 (de) | 1999-01-20 | 2000-07-27 | Basf Ag | Verfahren zur thermischen N¶2¶O-Zersetzung |
| JP2001220110A (ja) * | 2000-02-01 | 2001-08-14 | Daikin Ind Ltd | 医療用酸素発生器 |
| US6623714B2 (en) | 2001-06-04 | 2003-09-23 | Praxair Technology, Inc. | Oxygen separation method using a ceramic membrane unit |
| US8200775B2 (en) * | 2005-02-01 | 2012-06-12 | Newsilike Media Group, Inc | Enhanced syndication |
| US7118612B2 (en) | 2003-12-30 | 2006-10-10 | Praxair Technology, Inc. | Oxygen separation method utilizing an oxygen transport membrane reactor |
| AU2007308838B2 (en) * | 2006-10-25 | 2014-03-13 | Revalesio Corporation | Mixing device and output fluids of same |
| JP4714664B2 (ja) * | 2006-10-31 | 2011-06-29 | 新日本製鐵株式会社 | 酸素分離装置 |
| US8607769B2 (en) * | 2006-11-16 | 2013-12-17 | Siddhartha Gaur | Combustion controlled NOx reduction method and device |
| US10960168B2 (en) * | 2008-08-21 | 2021-03-30 | Vero Biotech LLC | Delivery of high concentration nitric oxide |
| US8696795B2 (en) * | 2009-12-17 | 2014-04-15 | Koninklijke Philips N.V. | Oxygen separation method and system with a plasma pump and a membrane |
| US8821828B2 (en) * | 2009-12-23 | 2014-09-02 | Koninklijke Philips N.V. | Method for generating nitric oxide |
| US20140000473A1 (en) * | 2010-02-02 | 2014-01-02 | Supersonic Tubevehicle Llc | Transportation system and vehicle for supersonic transport |
| US8012446B1 (en) * | 2010-07-08 | 2011-09-06 | Air Products And Chemicals, Inc. | Recycle TSA regen gas to boiler for oxyfuel operations |
| WO2012036748A1 (en) * | 2010-09-16 | 2012-03-22 | Littmann Robert J | Economical hybrid fuel |
-
2011
- 2011-09-14 EP EP11768141.1A patent/EP2619131B1/en not_active Not-in-force
- 2011-09-14 CN CN201180045832.XA patent/CN103124689B/zh not_active Expired - Fee Related
- 2011-09-14 WO PCT/IB2011/054018 patent/WO2012038860A1/en not_active Ceased
- 2011-09-14 BR BR112013006250-9A patent/BR112013006250B1/pt not_active IP Right Cessation
- 2011-09-14 US US13/822,672 patent/US8920539B2/en active Active
- 2011-09-14 JP JP2013528810A patent/JP5847181B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012038860A1 (en) | 2012-03-29 |
| EP2619131B1 (en) | 2019-04-03 |
| US20130177657A1 (en) | 2013-07-11 |
| JP2013543430A (ja) | 2013-12-05 |
| EP2619131A1 (en) | 2013-07-31 |
| JP5847181B2 (ja) | 2016-01-20 |
| US8920539B2 (en) | 2014-12-30 |
| CN103124689A (zh) | 2013-05-29 |
| BR112013006250A2 (pt) | 2020-06-09 |
| CN103124689B (zh) | 2016-03-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B25D | Requested change of name of applicant approved |
Owner name: KONINKLIJKE PHILIPS N.V. (NL) |
|
| B25G | Requested change of headquarter approved |
Owner name: KONINKLIJKE PHILIPS N.V. (NL) |
|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/09/2011, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 13A ANUIDADE. |
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| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2792 DE 09-07-2024 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |