BR112013004206A2 - new isolated bacteriophage containing specific bactericidal activity of e.g. coli and antibacterial composition comprising the same - Google Patents

new isolated bacteriophage containing specific bactericidal activity of e.g. coli and antibacterial composition comprising the same

Info

Publication number
BR112013004206A2
BR112013004206A2 BR112013004206A BR112013004206A BR112013004206A2 BR 112013004206 A2 BR112013004206 A2 BR 112013004206A2 BR 112013004206 A BR112013004206 A BR 112013004206A BR 112013004206 A BR112013004206 A BR 112013004206A BR 112013004206 A2 BR112013004206 A2 BR 112013004206A2
Authority
BR
Brazil
Prior art keywords
bacteriophage
coli
bactericidal activity
specific bactericidal
active ingredient
Prior art date
Application number
BR112013004206A
Other languages
Portuguese (pt)
Other versions
BR112013004206B1 (en
Inventor
Eun Mi Shin
Jae Won Kim
Si Yong Yang
Young Sa Kim
Young Wook Cho
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of BR112013004206A2 publication Critical patent/BR112013004206A2/en
Publication of BR112013004206B1 publication Critical patent/BR112013004206B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • A23K20/147Polymeric derivatives, e.g. peptides or proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/60Feeding-stuffs specially adapted for particular animals for weanlings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/32Foods, ingredients or supplements having a functional effect on health having an effect on the health of the digestive tract
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/00021Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/00032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

Abstract

novo bacteriófago isolado contendo atividade bactericida específica de e. coli e composição antibacteriana que compreende o mesmo. a presente invenção refere-se a um novo bacteriófago que tem uma atividade bactericida específica de e. coli, uma composição para a prevenção ou tratamento de doenças infecciosas causadas por e. coli enterotoxigênica compreendendo o bacteriófago como um ingrediente ativo, um antibiótico compreendendo o bacteriófago como um ingrediente ativo, uma composição de aditivo alimentar que compreende o bacteriófago como um ingrediente ativo, um desinfetante ou produto de limpeza compreendendo o bacteriófago como um ingrediente ativo, e um método para o tratamento de colibacilose utilizando o bacteriófago. o novo bacteriófago da presente invenção possui uma atividade bactericida específica contra e. coli patogênica, e excelente resistência a ácido e ao calor. portanto, o novo bacteriófago pode ser usado para a prevenção ou tratamento de colibacilose suína, que é uma doença infecciosa causada por e. coli patogênica, e também pode ser amplamente utilizado em composições de aditivos alimentares para animais, desinfetantes, e produtos de limpeza.new isolated bacteriophage containing specific bactericidal activity of e.g. coli and antibacterial composition comprising the same. The present invention relates to a novel bacteriophage which has a specific bactericidal activity of e.g. coli, a composition for the prevention or treatment of infectious diseases caused by e.g. enterotoxigenic coli comprising bacteriophage as an active ingredient, an antibiotic comprising bacteriophage as an active ingredient, a food additive composition comprising bacteriophage as an active ingredient, a disinfectant or cleaning product comprising bacteriophage as an active ingredient, and a method for the treatment of colibacillosis using the bacteriophage. The novel bacteriophage of the present invention has a specific bactericidal activity against e.g. pathogenic coli, and excellent resistance to acid and heat. therefore, the novel bacteriophage may be used for the prevention or treatment of swine colibacillosis, which is an infectious disease caused by e.g. pathogenic coli, and can also be widely used in animal feed additive, disinfectant, and cleaning product compositions.

BR112013004206-0A 2011-11-14 2012-11-14 COMPOSITION FOR PREVENTION OR TREATMENT OF INFECTIOUS DISEASES CAUSED BY ENTEROTOXIGENIC ESCHERICHIA COLI, ANTIBIOTIC, FEED ADDITIVE COMPOSITION AND SANITIZING OR CLEANING AGENT BR112013004206B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1020110118446A KR101260645B1 (en) 2011-11-14 2011-11-14 Novel isolated bacteriophage having e. coli specific antibacterial activity and antibacterial composition comprising the same
KR10-2011-0118446 2011-11-14
PCT/KR2012/009613 WO2013073843A1 (en) 2011-11-14 2012-11-14 Novel isolated bacteriophage having e. coli-specific bactericidal activity and antibacterial composition comprising the same

Publications (2)

Publication Number Publication Date
BR112013004206A2 true BR112013004206A2 (en) 2016-05-10
BR112013004206B1 BR112013004206B1 (en) 2021-09-21

Family

ID=48429850

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013004206-0A BR112013004206B1 (en) 2011-11-14 2012-11-14 COMPOSITION FOR PREVENTION OR TREATMENT OF INFECTIOUS DISEASES CAUSED BY ENTEROTOXIGENIC ESCHERICHIA COLI, ANTIBIOTIC, FEED ADDITIVE COMPOSITION AND SANITIZING OR CLEANING AGENT

Country Status (7)

Country Link
US (1) US9358258B2 (en)
EP (1) EP2780447B1 (en)
KR (1) KR101260645B1 (en)
CN (1) CN103946375B (en)
BR (1) BR112013004206B1 (en)
TW (1) TWI465570B (en)
WO (1) WO2013073843A1 (en)

Families Citing this family (27)

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Publication number Priority date Publication date Assignee Title
KR101381796B1 (en) * 2013-02-27 2014-04-25 씨제이제일제당 (주) Novel bacteriophage and antibacterial composition comprising the same
KR101381795B1 (en) 2013-02-27 2014-04-07 씨제이제일제당 (주) Novel bacteriophage and antibacterial composition comprising the same
KR101381793B1 (en) * 2013-02-27 2014-04-07 씨제이제일제당 (주) Novel bacteriophage and antibacterial composition comprising the same
KR101581654B1 (en) 2013-06-27 2015-12-31 주식회사 인트론바이오테크놀로지 Method for prevention and treatment of Escherichia coli Type K99
KR101590108B1 (en) * 2014-04-10 2016-01-29 씨제이제일제당(주) Novel bacteriophage and composition comprising the same
KR101591793B1 (en) 2014-04-15 2016-02-04 씨제이제일제당(주) Novel bacteriophage and composition comprising the same
KR101592177B1 (en) * 2014-05-07 2016-02-05 주식회사 인트론바이오테크놀로지 Method for prevention and treatment of Escherichia coli infection using a bacteriophage with broad antibacterial spectrum against Escherichia coli
KR101761573B1 (en) * 2014-12-29 2017-07-26 주식회사 인트론바이오테크놀로지 Novel enterohemorrhage Escherichia coli bacteriophage Esc-CHP-1 and its use for preventing proliferation of enterohemorrhage Escherichia coli
KR101761581B1 (en) * 2014-12-30 2017-07-26 주식회사 인트론바이오테크놀로지 Novel enteroinvasive Escherichia coli bacteriophage Esc-COP-4 and its use for preventing proliferation of enteroinvasive Escherichia coli
KR101649851B1 (en) * 2014-12-30 2016-08-30 주식회사 인트론바이오테크놀로지 Novel Shigatoxin-producing Escherichia coli type F18 bacteriophage Esc-COP-1 and its use for preventing proliferation of Shigatoxin-producing Escherichia coli type F18
KR101761578B1 (en) * 2014-12-30 2017-07-26 주식회사 인트론바이오테크놀로지 Novel enteropathogenic Escherichia coli bacteriophage Esc-CHP-2 and its use for preventing proliferation of enteropathogenic Escherichia coli
WO2016168560A1 (en) 2015-04-16 2016-10-20 Kennesaw State University Research And Service Foundation, Inc. Escherichia coli o157:h7 bacteriophage φ241
KR101699245B1 (en) 2015-12-21 2017-02-13 주식회사 인트론바이오테크놀로지 Novel Pasteurella Multocida bacteriophage Pas-MUP-1 and its use for preventing proliferation of Pasteurella Multocida
CN113677213A (en) * 2019-03-29 2021-11-19 普瑞纳动物营养有限公司 Bacteriophage animal feed preservative
CN110129283B (en) * 2019-05-24 2021-03-02 青岛诺安百特生物技术有限公司 Short-tail coliphage and application thereof
KR20220034163A (en) * 2019-07-09 2022-03-17 디에스엠 아이피 어셋츠 비.브이. Decreased viral activity of elafibrano and riboflavin or DHA
CN110607284A (en) * 2019-10-23 2019-12-24 青岛农业大学 Escherichia coli phage vB _ EcoM _ swi3 and application thereof
CN110846282B (en) * 2019-10-30 2023-04-07 菲吉乐科(南京)生物科技有限公司 High-temperature-resistant escherichia coli bacteriophage and composition, kit and application thereof
CN111053790B (en) * 2019-12-02 2023-04-07 衡阳师范学院 Pathogenic coliphage oral preparation and preparation method thereof
CN111057681B (en) * 2019-12-02 2023-02-28 衡阳师范学院 Bacteriophage and application thereof
CN111481574B (en) * 2020-04-17 2023-03-14 吉林省农业科学院 Combined phage preparation for treating piglet diarrhea
US11701398B2 (en) * 2020-06-04 2023-07-18 Intron Biotechnology, Inc. Compositions and methods for inhibiting the proliferation of pathogenic Escherichia coli
CN113201502B (en) * 2020-08-06 2022-09-27 青岛诺安百特生物技术有限公司 Coliphage for piglet diarrhea and application thereof
CN112262918A (en) * 2020-11-18 2021-01-26 内蒙古自治区农牧业科学院 Feed microecological bactericide suspending agent and preparation method thereof
CN113583976B (en) * 2021-08-05 2022-07-01 瑞科盟(青岛)生物工程有限公司 Phage composition and application thereof
CN114317458B (en) * 2021-12-31 2023-07-14 浙江省农业科学院 Coliphage with bactericidal effect and application thereof, bactericide and medicament
CN114292822B (en) * 2021-12-31 2023-07-14 浙江省农业科学院 Coliphage ZJRP5 and application thereof, bactericide and medicament

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2251724A1 (en) * 1996-04-15 1997-10-23 Paul Averback Compositions containing bacteriophages and methods of using bacteriophages to treat infections
US6485902B2 (en) 2000-06-06 2002-11-26 Thomas E. Waddell Use of bacteriophages for control of escherichia coli O157
KR100963157B1 (en) 2007-06-18 2010-06-15 재단법인서울대학교산학협력재단 Diagnostic method for colibacillosis in pigs
KR101151516B1 (en) * 2008-12-24 2012-05-30 씨제이제일제당 (주) Novel bacteriophage and antibacterial composition comprising the same
US8293515B2 (en) 2009-09-03 2012-10-23 CJ Cheijedang Corporation Salmonella bacteriophage and antibacterial composition comprising the same
CN101724607B (en) 2009-12-18 2012-05-09 江苏省农业科学院 Bacteriophage EK99-C of enterotoxigenic Escherichia coil ETEC-K99 and application thereof

Also Published As

Publication number Publication date
US20140356330A1 (en) 2014-12-04
TWI465570B (en) 2014-12-21
EP2780447A1 (en) 2014-09-24
CN103946375B (en) 2016-12-14
WO2013073843A1 (en) 2013-05-23
US9358258B2 (en) 2016-06-07
BR112013004206B1 (en) 2021-09-21
EP2780447A4 (en) 2015-08-12
CN103946375A (en) 2014-07-23
KR101260645B1 (en) 2013-05-03
EP2780447B1 (en) 2018-01-10
TW201326395A (en) 2013-07-01

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: A61K 35/76 (2015.01), A23K 20/147 (2016.01), A23K

B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/11/2012, OBSERVADAS AS CONDICOES LEGAIS.