BR112012028841A2 - composto derivado do ácido 1-(2-fluobifenil-4-il) - ciclopropanocarboxílico para a terapia de doenças priônicas - Google Patents

composto derivado do ácido 1-(2-fluobifenil-4-il) - ciclopropanocarboxílico para a terapia de doenças priônicas

Info

Publication number
BR112012028841A2
BR112012028841A2 BR112012028841A BR112012028841A BR112012028841A2 BR 112012028841 A2 BR112012028841 A2 BR 112012028841A2 BR 112012028841 A BR112012028841 A BR 112012028841A BR 112012028841 A BR112012028841 A BR 112012028841A BR 112012028841 A2 BR112012028841 A2 BR 112012028841A2
Authority
BR
Brazil
Prior art keywords
fluobiphenyl
treatment
acid derivative
cyclopropanecarboxylic acid
derivative compound
Prior art date
Application number
BR112012028841A
Other languages
English (en)
Inventor
Bruno Pietro Imbimbo
Gino Villetti
Giorgio Poli
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of BR112012028841A2 publication Critical patent/BR112012028841A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/16—Unsaturated compounds
    • C07C61/40—Unsaturated compounds containing halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/04—Saturated compounds having a carboxyl group bound to a three or four-membered ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BR112012028841A 2010-06-04 2011-05-31 composto derivado do ácido 1-(2-fluobifenil-4-il) - ciclopropanocarboxílico para a terapia de doenças priônicas BR112012028841A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10164967 2010-06-04
PCT/EP2011/058956 WO2011151330A1 (en) 2010-06-04 2011-05-31 1-(2-fluorobiphenyl-4-yl)-cyclopropanecarboxylic acid derivatives for the therapy of prion diseases

Publications (1)

Publication Number Publication Date
BR112012028841A2 true BR112012028841A2 (pt) 2016-07-26

Family

ID=43014399

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012028841A BR112012028841A2 (pt) 2010-06-04 2011-05-31 composto derivado do ácido 1-(2-fluobifenil-4-il) - ciclopropanocarboxílico para a terapia de doenças priônicas

Country Status (9)

Country Link
US (1) US20120022163A1 (pt)
EP (1) EP2575797A1 (pt)
KR (1) KR20130080795A (pt)
CN (1) CN102905701A (pt)
AR (1) AR081574A1 (pt)
BR (1) BR112012028841A2 (pt)
CA (1) CA2801449A1 (pt)
RU (1) RU2012151850A (pt)
WO (1) WO2011151330A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9592210B2 (en) 2011-12-22 2017-03-14 Chiesi Farmaceutici S.P.A. 1-phenylalkanecarboxylic acid derivatives for the treatment of cognitive impairment
WO2015181094A1 (en) * 2014-05-26 2015-12-03 Chiesi Farmaceutici S.P.A. 1-(2-fluorobiphenyl-4-yl)-cyclopropanecarboxylic acid derivatives for the treatment of down's syndrome

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137114A1 (en) * 2001-01-19 2002-09-26 Dirk Voelkel Method of detecting PrP protein and kits therefor
ATE409176T1 (de) * 2003-02-21 2008-10-15 Chiesi Farma Spa 1-phenylalkancarbonsäurederivate zur behandlung neurodegenerativer erkrankungen
SE0401601D0 (sv) * 2004-06-21 2004-06-21 Bioarctic Neuroscience Ab Protofibril specific antibodies and uses thereof
PT1778623E (pt) 2004-08-03 2008-09-29 Chiesi Farma Spa Derivados dos ácidos 1-fenilalcanocarboxílicos para o tratamento de doenças neurodegenerativas
WO2008036733A2 (en) * 2006-09-19 2008-03-27 Myriad Genetics, Inc. Methods for treatment of vesicle transport disorders
EP2133322A1 (en) 2008-06-11 2009-12-16 CHIESI FARMACEUTICI S.p.A. Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid

Also Published As

Publication number Publication date
CN102905701A (zh) 2013-01-30
EP2575797A1 (en) 2013-04-10
KR20130080795A (ko) 2013-07-15
US20120022163A1 (en) 2012-01-26
RU2012151850A (ru) 2014-07-20
AR081574A1 (es) 2012-10-03
WO2011151330A1 (en) 2011-12-08
CA2801449A1 (en) 2011-12-08

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2386 DE 27-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B350 Update of information on the portal [chapter 15.35 patent gazette]