BR102014011436A8 - fibrin sealant for topical use, method of formation of fibrin and its use - Google Patents

fibrin sealant for topical use, method of formation of fibrin and its use

Info

Publication number
BR102014011436A8
BR102014011436A8 BR102014011436A BR102014011436A BR102014011436A8 BR 102014011436 A8 BR102014011436 A8 BR 102014011436A8 BR 102014011436 A BR102014011436 A BR 102014011436A BR 102014011436 A BR102014011436 A BR 102014011436A BR 102014011436 A8 BR102014011436 A8 BR 102014011436A8
Authority
BR
Brazil
Prior art keywords
fibrin
formation
sealant
fibrin sealant
topical
Prior art date
Application number
BR102014011436A
Other languages
Portuguese (pt)
Other versions
BR102014011436A2 (en
Inventor
Barraviera Benedito
Seabra Ferreira Junior Rui
Regina Catharino Sartori Barraviera Silvia
Original Assignee
Univ Estadual Paulista Julio De Mesquita Filho
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54479064&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR102014011436(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Estadual Paulista Julio De Mesquita Filho filed Critical Univ Estadual Paulista Julio De Mesquita Filho
Priority to BR102014011436A priority Critical patent/BR102014011436A8/en
Priority to PCT/BR2015/000065 priority patent/WO2015172215A1/en
Publication of BR102014011436A2 publication Critical patent/BR102014011436A2/en
Publication of BR102014011436A8 publication Critical patent/BR102014011436A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/58—Reptiles
    • A61K35/583—Snakes; Lizards, e.g. chameleons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

resumo selante de fibrina para uso tópico, método de formação do mesmo e seu uso a presente invenção descreve um selante de fibrina, o qual compreende uma serinoprotease extraída a partir de veneno de serpente, um crioprecipitado rico em fibrinogênio extraído de bubalinos e o diluente cloreto de cálcio. a invenção ainda ensina o método de formação do selante, cujos componentes são providos separadamente e polimerizam-se in situ após mistura, bem como seu uso. o selante de fibrina descrito apresenta inúmeras aplicações médicas tópicas e não há o risco de transmitir doenças infecciosas.Summary of Fibrin Sealant for Topical Use, Method of Formation thereof and Its Use The present invention describes a fibrin sealant which comprises a serinoprotease extracted from snake venom, a fibrinogen rich cryoprecipitate extracted from buffaloes and the chloride diluent. of calcium. The invention further teaches the method of sealant formation, the components of which are provided separately and polymerize in situ after mixing, as well as their use. The fibrin sealant described has numerous topical medical applications and there is no risk of transmitting infectious diseases.

BR102014011436A 2014-05-12 2014-05-12 fibrin sealant for topical use, method of formation of fibrin and its use BR102014011436A8 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
BR102014011436A BR102014011436A8 (en) 2014-05-12 2014-05-12 fibrin sealant for topical use, method of formation of fibrin and its use
PCT/BR2015/000065 WO2015172215A1 (en) 2014-05-12 2015-05-08 Fibrin sealant for topical use, method for producing same and use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BR102014011436A BR102014011436A8 (en) 2014-05-12 2014-05-12 fibrin sealant for topical use, method of formation of fibrin and its use

Publications (2)

Publication Number Publication Date
BR102014011436A2 BR102014011436A2 (en) 2016-02-23
BR102014011436A8 true BR102014011436A8 (en) 2018-01-09

Family

ID=54479064

Family Applications (1)

Application Number Title Priority Date Filing Date
BR102014011436A BR102014011436A8 (en) 2014-05-12 2014-05-12 fibrin sealant for topical use, method of formation of fibrin and its use

Country Status (2)

Country Link
BR (1) BR102014011436A8 (en)
WO (1) WO2015172215A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR102017008027B1 (en) * 2017-04-18 2022-04-19 Cristália Produtos Químicos Farmacêuticos Ltda Process for obtaining fibrin biopolymer, means for applying said fibrin biopolymer, and process for applying said fibrin biopolymer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1091315A (en) * 1992-10-08 1994-08-31 E·R·斯奎布父子公司 Fibrin sealant compositions and using method thereof
EP1765851B1 (en) * 2004-05-06 2011-11-16 Laboratório Biosintética Ltda. Analog compounds of analgesic peptides derived from the venom of crotalus durissus terrificus snakes, their uses, compositions, methods of preparation and purification
EP2010238A2 (en) * 2006-04-20 2009-01-07 Vivolution A/S Improved fibrin sealant composition and its use
IL207586A0 (en) * 2010-08-12 2010-12-30 Omrix Biopharmaceuticals Ltd A fibrin based therapeutic preparation and use thereof

Also Published As

Publication number Publication date
BR102014011436A2 (en) 2016-02-23
WO2015172215A1 (en) 2015-11-19

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Legal Events

Date Code Title Description
B03A Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette]
B03H Publication of an application: rectification [chapter 3.8 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal: appeal against refusal
B12B Appeal: appeal against refusal
B12G Appeal: publication cancelled

Free format text: ANULADA A PUBLICACAO CODIGO 12.2 NA RPI NO 2626 DE 04/05/2021 POR TER SIDO INDEVIDA.