BR0307895A - Human analogs of the deubiquitination protease murine genes - Google Patents

Human analogs of the deubiquitination protease murine genes

Info

Publication number
BR0307895A
BR0307895A BR0307895-7A BR0307895A BR0307895A BR 0307895 A BR0307895 A BR 0307895A BR 0307895 A BR0307895 A BR 0307895A BR 0307895 A BR0307895 A BR 0307895A
Authority
BR
Brazil
Prior art keywords
deubiquitination
protease
human
murine genes
murine
Prior art date
Application number
BR0307895-7A
Other languages
Portuguese (pt)
Inventor
Chang Hahn
Hong Liu
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0208404.4A external-priority patent/GB0208404D0/en
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of BR0307895A publication Critical patent/BR0307895A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)

Abstract

"ANáLOGOS HUMANOS DOS GENES MURINOS DA PROTEASE DE DESUBIQUITINAçãO". A presente invenção está direcionada a análogos humanos de proteases de desubiquitinação que podem ser induzidas por citocinas específicas hematopoiéticas murinas ('DUBs') agrupadas nos cromossomos 4 e 8 e às suas respectivas regiões reguladoras. Os nucleotídeos ou as proteínas codificadas pelos mesmos podem ser utilizadas em ensaios para identificar inibidores das DUBs humanas."Human Analogies of the Murine Genes of Desubiquitination Protein". The present invention is directed to human deubiquitination protease analogues which may be induced by murine hematopoietic specific cytokines ('DUBs') grouped on chromosomes 4 and 8 and their respective regulatory regions. Nucleotides or proteins encoded by them may be used in assays to identify human DUB inhibitors.

BR0307895-7A 2002-02-22 2003-02-20 Human analogs of the deubiquitination protease murine genes BR0307895A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US35887502P 2002-02-22 2002-02-22
US35887302P 2002-02-22 2002-02-22
US36302002P 2002-03-08 2002-03-08
GBGB0208404.4A GB0208404D0 (en) 2002-03-08 2002-04-12 Human analogues of murine deubiquitinating protease genes
PCT/US2003/005338 WO2003072724A2 (en) 2002-02-22 2003-02-20 Human analogs of murine deubiquitinating protease genes

Publications (1)

Publication Number Publication Date
BR0307895A true BR0307895A (en) 2006-01-17

Family

ID=27767875

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0307895-7A BR0307895A (en) 2002-02-22 2003-02-20 Human analogs of the deubiquitination protease murine genes

Country Status (7)

Country Link
EP (1) EP1534825A4 (en)
AU (1) AU2003215370B2 (en)
BR (1) BR0307895A (en)
CA (1) CA2476770A1 (en)
IL (1) IL163528A0 (en)
MX (1) MXPA04007760A (en)
WO (1) WO2003072724A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005049818A2 (en) * 2003-11-14 2005-06-02 The Queen's University Of Belfast Genes encoding human deubiquitinating enzymes
EP2049128A2 (en) * 2006-05-12 2009-04-22 The Queen's University of Belfast Dub3 as a cancer therapy target

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2229204C (en) * 1995-08-09 2012-10-09 Alan D. D'andrea Deubiquitinating enzymes that regulate cell growth
WO2000001817A2 (en) * 1998-07-06 2000-01-13 Schering Corporation Mammalian genes; dendritic cell prostaglandin-like transponder (dc-pgt), hdtea84, hsljd37r and rankl, hcc5 chemokine, deubiquitinating 11 and 12 (dub11, dub12), md-1, md2 and cyclin e2, related reagents and methods
WO2005049818A2 (en) * 2003-11-14 2005-06-02 The Queen's University Of Belfast Genes encoding human deubiquitinating enzymes

Also Published As

Publication number Publication date
MXPA04007760A (en) 2005-08-15
AU2003215370A1 (en) 2003-09-09
EP1534825A4 (en) 2006-02-01
AU2003215370B2 (en) 2008-06-12
CA2476770A1 (en) 2003-09-04
EP1534825A2 (en) 2005-06-01
IL163528A0 (en) 2005-12-18
WO2003072724A2 (en) 2003-09-04
WO2003072724A3 (en) 2005-04-07

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Legal Events

Date Code Title Description
B25G Requested change of headquarter approved

Owner name: AVENTIS PHARMACEUTICALS, INC. (US)

Free format text: SEDE ALTERADA CONFORME SOLICITADO NA PETICAO NO 020070165509/RJ DE 23/11/2007.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A E 9A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE AS 8A E 9A ANUIDADES.