BR0206690A - Processos para a identificação da função do gene, para alteração da expressão de fatores celulares e para alteração do fenótipo de célula - Google Patents

Processos para a identificação da função do gene, para alteração da expressão de fatores celulares e para alteração do fenótipo de célula

Info

Publication number
BR0206690A
BR0206690A BR0206690-4A BR0206690A BR0206690A BR 0206690 A BR0206690 A BR 0206690A BR 0206690 A BR0206690 A BR 0206690A BR 0206690 A BR0206690 A BR 0206690A
Authority
BR
Brazil
Prior art keywords
altering
processes
gene function
cell phenotype
cellular factors
Prior art date
Application number
BR0206690-4A
Other languages
English (en)
Inventor
Boro Dropulic
Original Assignee
Virxsys Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virxsys Corp filed Critical Virxsys Corp
Publication of BR0206690A publication Critical patent/BR0206690A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)

Abstract

"PROCESSOS PARA A IDENTIFICAçãO DA FUNçãO DO GENE, PARA ALTERAçãO DA EXPRESSãO DE FATORES CELULARES E PARA ALTERAçãO DO FENóTIPO DE CéLULA". A presente invenção refere-se a métodos e a composições para a eficiente identificação de uma ou mais funcionalidades de um produto codificado por uma seq³ência de ácido nucléico de interesse. Os métodos utilizam as capacidades de super e/ou subexpressar o produto em uma célula, assim como a combinação destes resultados, para permitir a identificação de pelo menos um da funcionalidade celular ou in vivo do produto.
BR0206690-4A 2001-01-25 2002-01-25 Processos para a identificação da função do gene, para alteração da expressão de fatores celulares e para alteração do fenótipo de célula BR0206690A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26427201P 2001-01-25 2001-01-25
PCT/US2002/002287 WO2002059378A2 (en) 2001-01-25 2002-01-25 Methods and compositions for identifying gene function

Publications (1)

Publication Number Publication Date
BR0206690A true BR0206690A (pt) 2006-01-17

Family

ID=23005310

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0206690-4A BR0206690A (pt) 2001-01-25 2002-01-25 Processos para a identificação da função do gene, para alteração da expressão de fatores celulares e para alteração do fenótipo de célula

Country Status (15)

Country Link
US (2) US7427474B2 (pt)
EP (1) EP1392857B1 (pt)
JP (1) JP2005508602A (pt)
KR (1) KR20030090626A (pt)
CN (1) CN100475974C (pt)
AT (1) ATE455863T1 (pt)
AU (1) AU2002241980B2 (pt)
BR (1) BR0206690A (pt)
CA (1) CA2441209C (pt)
DE (1) DE60235161D1 (pt)
IL (1) IL157087A0 (pt)
MX (1) MXPA03006624A (pt)
NZ (1) NZ527719A (pt)
WO (1) WO2002059378A2 (pt)
ZA (1) ZA200305729B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050106732A1 (en) * 2001-04-20 2005-05-19 Kingsman Susan A. Vector system

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817491A (en) * 1990-09-21 1998-10-06 The Regents Of The University Of California VSV G pseusdotyped retroviral vectors
US6372965B1 (en) * 1992-11-17 2002-04-16 E.I. Du Pont De Nemours And Company Genes for microsomal delta-12 fatty acid desaturases and hydroxylases from plants
US5814500A (en) * 1996-10-31 1998-09-29 The Johns Hopkins University School Of Medicine Delivery construct for antisense nucleic acids and methods of use
CA2277414A1 (en) * 1997-11-07 1999-05-20 Georges Natsoulis Surrogate genetics target characterization method
AU761367B2 (en) * 1998-01-16 2003-06-05 Large Scale Biology Corporation Method of determining the function of nucleotide sequences and the proteins they encode by transfecting the same into a host
GB9803351D0 (en) 1998-02-17 1998-04-15 Oxford Biomedica Ltd Anti-viral vectors
US6413776B1 (en) * 1998-06-12 2002-07-02 Galapagos Geonomics N.V. High throughput screening of gene function using adenoviral libraries for functional genomics applications
GB9827152D0 (en) * 1998-07-03 1999-02-03 Devgen Nv Characterisation of gene function using double stranded rna inhibition
WO2000024912A1 (en) * 1998-10-23 2000-05-04 The Children's Medical Center Corporation Use of a self-cleaving rna motif to modulate gene expression
EP1165842A4 (en) * 1999-03-16 2004-07-07 Dana Farber Cancer Inst Inc LENTIVIRAL VECTOR SYSTEMS FOR SCREENING LARGE QUANTITIES
US20040018570A1 (en) * 1999-09-01 2004-01-29 Brown University Kinase inhibitors and methods of use in screening assays and modulation of cell proliferation and growth
US6627442B1 (en) * 2000-08-31 2003-09-30 Virxsys Corporation Methods for stable transduction of cells with hiv-derived viral vectors
RU2301260C2 (ru) 2000-09-22 2007-06-20 Вирэкссис Корпорейшн Вирусные векторы с зависимой от условий репликацией и их применение

Also Published As

Publication number Publication date
US20090081682A1 (en) 2009-03-26
ZA200305729B (en) 2007-02-28
JP2005508602A (ja) 2005-04-07
AU2002241980B2 (en) 2008-01-31
ATE455863T1 (de) 2010-02-15
EP1392857A2 (en) 2004-03-03
NZ527719A (en) 2006-12-22
WO2002059378A2 (en) 2002-08-01
CA2441209A1 (en) 2002-08-01
CN100475974C (zh) 2009-04-08
CN1524126A (zh) 2004-08-25
US7427474B2 (en) 2008-09-23
MXPA03006624A (es) 2004-11-12
DE60235161D1 (de) 2010-03-11
WO2002059378A3 (en) 2003-12-18
IL157087A0 (en) 2004-02-08
KR20030090626A (ko) 2003-11-28
EP1392857B1 (en) 2010-01-20
US20040203017A1 (en) 2004-10-14
CA2441209C (en) 2012-11-13

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A E 8A A NUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2055 DE 25/05/2010.