BR0202064A - Método para identificação de um peptìdeo artimicrobiano, peptìdeo antimicrobiano isolado, análogos dos peptìdeos, seus usos, molécula de ácido nucleico isolada, vetor de expressão, célula hospedeira, método para prevenir o crescimento, inibir o crescimento ou reduzir a viabilidade de um microorganismo e método de tratamento de um organismo infectado com um microorganismo patogênico - Google Patents

Método para identificação de um peptìdeo artimicrobiano, peptìdeo antimicrobiano isolado, análogos dos peptìdeos, seus usos, molécula de ácido nucleico isolada, vetor de expressão, célula hospedeira, método para prevenir o crescimento, inibir o crescimento ou reduzir a viabilidade de um microorganismo e método de tratamento de um organismo infectado com um microorganismo patogênico

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Publication number
BR0202064A
BR0202064A BR0202064-5A BRPI0202064A BR0202064A BR 0202064 A BR0202064 A BR 0202064A BR PI0202064 A BRPI0202064 A BR PI0202064A BR 0202064 A BR0202064 A BR 0202064A
Authority
BR
Brazil
Prior art keywords
peptide
microorganism
isolated
identifying
nucleic acid
Prior art date
Application number
BR0202064-5A
Other languages
English (en)
Inventor
Adilson Leite
Urara Kawazoe
Paulo Arruda
Arnaldo Da Junior Silva
Original Assignee
Fundacao De Amparo A Pesquisa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundacao De Amparo A Pesquisa filed Critical Fundacao De Amparo A Pesquisa
Publication of BR0202064A publication Critical patent/BR0202064A/pt
Publication of BRPI0202064B1 publication Critical patent/BRPI0202064B1/pt
Publication of BRPI0202064B8 publication Critical patent/BRPI0202064B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/44—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from protozoa
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Abstract

"MéTODO PARA IDENTIFICAçãO DE UM PEPTìDEO ANTIMICROBIANO, PEPTìDEO ANTIMICROBIANO ISOLADO, ANáLOGOS DOS PEPTìDEOS, SEUS USOS, MOLéCULA DE áCIDO NUCLEICO ISOLADA, VETOR DE EXPRESSãO, CéLULA HOSPEDEIRA, MéTODO PARA PREVENIR O CRESCIMENTO, INIBIR O CRESCIMENTO OU REDUZIR A VIABILIDADE DE UM MICROORGANISMO E MéTODO DE TRATAMENTO DE UM ORGANISMO INFECTADO COM UM MICROORGANISMO PATOGêNICO". A presente invenção se refere a um método para identificação de peptídeos que apresentam atividade antimicrobiana, aos peptídeos antimicrobianos identificados desse modo e métodos para seu uso.
BR0202064-5 2001-06-01 2002-05-29 método para identificação de um peptídeo antimicrobiano BRPI0202064B8 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/870,498 US7550558B2 (en) 2001-06-01 2001-06-01 Antimicrobial peptides and methods for identifying and using such peptides

Publications (3)

Publication Number Publication Date
BR0202064A true BR0202064A (pt) 2003-04-22
BRPI0202064B1 BRPI0202064B1 (pt) 2018-11-21
BRPI0202064B8 BRPI0202064B8 (pt) 2021-05-25

Family

ID=25355506

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0202064-5 BRPI0202064B8 (pt) 2001-06-01 2002-05-29 método para identificação de um peptídeo antimicrobiano

Country Status (3)

Country Link
US (1) US7550558B2 (pt)
EP (2) EP1892246A3 (pt)
BR (1) BRPI0202064B8 (pt)

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US7550558B2 (en) * 2001-06-01 2009-06-23 Fundacao De Ampara A Pesquiso Do Estado De Sao Paolo (Fapesp) Antimicrobial peptides and methods for identifying and using such peptides
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US8682619B2 (en) * 2005-12-14 2014-03-25 The Invention Science Fund I, Llc Device including altered microorganisms, and methods and systems of use
US8734823B2 (en) * 2005-12-14 2014-05-27 The Invention Science Fund I, Llc Device including altered microorganisms, and methods and systems of use
US20110172826A1 (en) * 2005-12-14 2011-07-14 Amodei Dario G Device including altered microorganisms, and methods and systems of use
US8278094B2 (en) 2005-12-14 2012-10-02 The Invention Science Fund I, Llc Bone semi-permeable device
US20110184387A1 (en) * 2010-01-22 2011-07-28 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Compositions and methods for therapeutic delivery with microorganisms
US8246966B2 (en) 2006-08-07 2012-08-21 University Of Georgia Research Foundation, Inc. Trypanosome microsome system and uses thereof
WO2008021092A2 (en) * 2006-08-07 2008-02-21 University Of Georgia Research Foundation, Inc. Trypanosome microsome system and uses thereof
EP2088863A2 (en) 2006-11-22 2009-08-19 University Of Georgia Research Foundation, Inc. Tyrosine kinase inhibitors as anti-kinetolastid and anti-apicomplexan agents
WO2009103128A1 (en) * 2008-02-21 2009-08-27 The University Of Sydney Detection of anti-parasitic compounds
CA2749082A1 (en) * 2009-01-06 2010-07-15 C3 Jian, Inc. Targeted antimicrobial moieties
US11028137B2 (en) 2017-02-01 2021-06-08 The Research Foundation For The State University Of New York Mutant islet amyloid polypeptides with improved solubility and methods for using the same
WO2019236761A1 (en) * 2018-06-06 2019-12-12 Syngulon Sa Engineering antimicrobial peptides
CN110606870B (zh) * 2019-09-18 2021-02-19 广东省农业科学院动物卫生研究所 用于防治柔嫩艾美耳球虫的多肽及含有其的药物组合物
CN116375877B (zh) * 2022-12-01 2023-10-27 东北农业大学 一种细胞穿透抗菌肽pw2及其制备方法和应用

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US5324716A (en) * 1991-06-14 1994-06-28 Regents Of The University Of California Broad spectrum antimicrobial compounds and methods of use
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Also Published As

Publication number Publication date
US7550558B2 (en) 2009-06-23
EP1262556A3 (en) 2004-09-29
BRPI0202064B8 (pt) 2021-05-25
EP1892246A3 (en) 2008-07-23
US20030148397A1 (en) 2003-08-07
BRPI0202064B1 (pt) 2018-11-21
EP1262556A2 (en) 2002-12-04
EP1892246A2 (en) 2008-02-27

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