BR0111494A - Gel-forming free-flowing powder suitable for use as a vaccine, process for preparing it, dosage container for a needleless syringe, needleless syringe, vaccine composition, method for vaccinating an individual, suitable powder for use as a vaccine. a vaccine, and process for preparing it - Google Patents

Gel-forming free-flowing powder suitable for use as a vaccine, process for preparing it, dosage container for a needleless syringe, needleless syringe, vaccine composition, method for vaccinating an individual, suitable powder for use as a vaccine. a vaccine, and process for preparing it

Info

Publication number
BR0111494A
BR0111494A BR0111494-8A BR0111494A BR0111494A BR 0111494 A BR0111494 A BR 0111494A BR 0111494 A BR0111494 A BR 0111494A BR 0111494 A BR0111494 A BR 0111494A
Authority
BR
Brazil
Prior art keywords
vaccine
preparing
needleless syringe
gel
powder
Prior art date
Application number
BR0111494-8A
Other languages
Portuguese (pt)
Inventor
Yuh-Fun Maa
Lu Zhao
Steven Jpseph Prestrelski
Original Assignee
Powderject Vaccines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Powderject Vaccines Inc filed Critical Powderject Vaccines Inc
Publication of BR0111494A publication Critical patent/BR0111494A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

"Pó DE LIVRE ESCOAMENTO FORMADOR DE GEL ADEQUADO PARA USO COMO UMA VACINA, PROCESSO PARA A PREPARAçãO DO MESMO, RECEPTáCULO DE DOSAGEM PARA UMA SERINGA SEM AGULHA, SERINGA SEM AGULHA, COMPOSIçãO DE VACINA, MéTODO PARA VACINAçãO DE UM INDIVìDUO, Pó ADEQUADO PARA USO COMO UMA VACINA, E, PROCESSO PARA A PREPARAçãO DO MESMO". Um pó de livre escoamento formador de gel adequado para uso como uma vacina é preparado por secagem por pulverização ou secagem-congelamento por pulverização de uma suspensão aquosa que contém uma geralmente adsorvido em um adjuvante de sal de alumínio ou sal de cálcio, um sacarídeo, um aminoácido ou um sal do mesmo, e uma substância coloidal. O pó para fins de vacina são também preparados por secagem-congelamento por pulverização de uma suspensão aquosa de tal adjuvante tendo um antígeno adsorvido sobre o mesmo. Os processos para formar estas composições de pó são também descritos, assim como métodos para usar as composições em um procedimento de vacinação."FREE-DRINKING GEL FORMER DUST FOR USE AS A VACCINE, PROCESS FOR PREPARING THE SAME, DOSING RECEIVER FOR A NEEDLE SYRINGE, NEEDLE SYRINGE, VACCINE COMPOSITION, INDIVIDUAL VACCINATION METHOD LIKE A VACCINE, AND PROCESS FOR PREPARING IT ". A free-flowing gel-forming powder suitable for use as a vaccine is prepared by spray drying or spray freeze-drying an aqueous suspension containing one generally adsorbed on an aluminum salt or calcium salt adjuvant, a saccharide, an amino acid or a salt thereof, and a colloidal substance. Vaccine powders are also prepared by spray freeze-drying an aqueous suspension of such an adjuvant having an antigen adsorbed onto it. Processes for forming these powder compositions are also described, as are methods for using the compositions in a vaccination procedure.

BR0111494-8A 2000-06-08 2001-06-08 Gel-forming free-flowing powder suitable for use as a vaccine, process for preparing it, dosage container for a needleless syringe, needleless syringe, vaccine composition, method for vaccinating an individual, suitable powder for use as a vaccine. a vaccine, and process for preparing it BR0111494A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21058100P 2000-06-08 2000-06-08
US59077700A 2000-06-08 2000-06-08
PCT/US2001/018494 WO2001093829A2 (en) 2000-06-08 2001-06-08 Powder compositions

Publications (1)

Publication Number Publication Date
BR0111494A true BR0111494A (en) 2004-01-13

Family

ID=26905296

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0111494-8A BR0111494A (en) 2000-06-08 2001-06-08 Gel-forming free-flowing powder suitable for use as a vaccine, process for preparing it, dosage container for a needleless syringe, needleless syringe, vaccine composition, method for vaccinating an individual, suitable powder for use as a vaccine. a vaccine, and process for preparing it

Country Status (11)

Country Link
EP (1) EP1289494A2 (en)
JP (1) JP2003535119A (en)
KR (1) KR20030020294A (en)
CN (1) CN1438874A (en)
AU (1) AU2001275371B9 (en)
BR (1) BR0111494A (en)
CA (1) CA2412197A1 (en)
IL (1) IL153241A0 (en)
MX (1) MXPA02012039A (en)
NZ (2) NZ523103A (en)
WO (1) WO2001093829A2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2449593A1 (en) * 2001-06-08 2002-12-19 Powderject Vaccines, Inc. Spray freeze-dried compositions
CN1607941A (en) * 2001-11-19 2005-04-20 贝克顿迪肯森公司 Pharmaceutical compositions in particulate form
US7923029B2 (en) 2002-04-11 2011-04-12 Medimmune Llc Spray freeze dry of compositions for pulmonary administration
DE10339197A1 (en) * 2003-08-22 2005-03-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Spray-dried amorphous powder with low residual moisture and good storage stability
JP2008514644A (en) * 2004-09-28 2008-05-08 アルザ コーポレイション Stabilization of alum adjuvant immunoactive agent
JP5349043B2 (en) * 2005-06-27 2013-11-20 アプライド シン フィルムズ，インコーポレイティッド Aluminum phosphate microspheres
RU2008117396A (en) 2005-10-04 2009-11-10 Альк-Абелло А/С (Dk) SOLID VACCINE COMPOSITION
EP1945249A2 (en) * 2005-11-01 2008-07-23 Novartis AG Compositions with antigens adsorbed to calcium phosphate
US20080226729A1 (en) * 2006-09-08 2008-09-18 Becton, Dickinson And Company Stable powder formulations of alum-adsorbed vaccines
US9017697B2 (en) 2006-10-12 2015-04-28 The University Of Queensland Compositions and methods for modulating immune responses
DK2131857T3 (en) * 2007-03-22 2015-09-14 Univ Colorado Regents A method of producing an immunologically active adjuvansbundet dried vaccine composition
JP2010534622A (en) * 2007-07-26 2010-11-11 サノフィ パストゥール リミテッド Antigen-adjuvant compositions and methods
EP2589392B1 (en) 2008-03-05 2016-11-30 Sanofi Pasteur Process for stabilizing an adjuvant containing vaccine composition
EP2344188B1 (en) 2008-10-02 2017-02-15 Pharmathene Inc. Anthrax vaccine formulation and uses thereof
CN102892409B (en) * 2010-03-31 2015-12-09 稳定性科技有限公司 For preserving the method for Alum adjuvant and aluminum salt-adjuvanted vaccine
AU2011234264B2 (en) 2010-03-31 2016-02-04 Stabilitech Ltd Excipients for stabilising viral particles, polypeptides or biological material
JP5960120B2 (en) 2010-03-31 2016-08-02 スタビリテック リミテッド Stabilization of virus particles
AU2011325857A1 (en) 2010-11-01 2013-05-02 University Of Technology, Sydney Immune-modulating agents and uses therefor
EA201390812A1 (en) 2010-12-02 2013-11-29 Онколитикс Байотек Инк. LYOPHYLIZED VIRUS COMPOSITIONS
CN103347535B (en) 2010-12-02 2015-11-25 昂科利蒂克斯生物科技公司 Liquid virus preparation
CN102133396B (en) * 2011-03-16 2013-10-16 中国人民解放军第三〇二医院 Vaccine injection and preparation method thereof
GB201117233D0 (en) 2011-10-05 2011-11-16 Stabilitech Ltd Stabilisation of polypeptides
US9827303B2 (en) * 2012-03-05 2017-11-28 De Staat Der Nederlanden, Vert. Door De Minister Van Vws, Ministerie Van Volksgezondheid, Welzijn En Sport Methods and compositions for stabilizing dried biological materials
KR101441539B1 (en) * 2013-04-01 2014-09-18 재단법인 유타 인하 디디에스 및 신의료기술개발 공동연구소 Adhesive compositions having improved hygroscopicity and preparation methods thereof
CN103641886B (en) * 2013-11-26 2015-07-29 精晶药业股份有限公司 A kind of process for purification of glutamine dipeptide
GB201406569D0 (en) 2014-04-11 2014-05-28 Stabilitech Ltd Vaccine compositions
GB2562241B (en) 2017-05-08 2022-04-06 Stabilitech Biopharma Ltd Vaccine compositions

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2505657A1 (en) * 1981-05-13 1982-11-19 Pasteur Institut IMPROVEMENTS IN LIVE STABILIZING AGENTS FOR THE PREPARATION OF VACCINES, AND STABILIZED VACCINES CONTAINING SAID STABILIZING AGENTS
HU188847B (en) * 1983-02-22 1986-05-28 Human Oltoanyagtermeloe Es Kutato Intezet,Hu Process for producing liophylized combined vaccines
JPS6013718A (en) * 1983-07-05 1985-01-24 Chemo Sero Therapeut Res Inst B-type hepatitis vaccine
JP2749449B2 (en) * 1992-12-28 1998-05-13 ユー、シイ−チャン Non-volatile semiconductor memory cell
JP3583128B2 (en) * 1993-01-08 2004-10-27 シーエスエル、リミテッド Vaccine preparation
TW360548B (en) * 1993-04-08 1999-06-11 Powderject Res Ltd Products for therapeutic use
US5902565A (en) * 1993-12-24 1999-05-11 Csl Limited Spray dried vaccine preparation comprising aluminium adsorbed immunogens
RU2096042C1 (en) * 1996-11-06 1997-11-20 Виктор Иванович Ситьков Method of preparing multipartial vaccine for leptospirosis control in animals
WO1999027961A1 (en) * 1997-12-02 1999-06-10 Powderject Vaccines, Inc. Transdermal delivery of particulate vaccine compositions

Also Published As

Publication number Publication date
AU7537101A (en) 2001-12-17
EP1289494A2 (en) 2003-03-12
NZ552576A (en) 2008-06-30
KR20030020294A (en) 2003-03-08
WO2001093829A3 (en) 2002-06-13
JP2003535119A (en) 2003-11-25
WO2001093829A2 (en) 2001-12-13
IL153241A0 (en) 2003-07-06
NZ523103A (en) 2005-08-26
MXPA02012039A (en) 2003-06-06
CA2412197A1 (en) 2001-12-13
AU2001275371B9 (en) 2007-06-07
AU2001275371B2 (en) 2006-12-21
CN1438874A (en) 2003-08-27

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT.CL: A61K 9/00

Ipc: A61K 9/14 (2010.01), A61K 9/19 (2010.01), A61K 39/

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 10(VIII), 13 E 25 DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.