BR0105530A - Parainfluenza virus, methods for stimulating a patient's immune system to induce protection against parainfluenza virus and for producing a particle of parainfluenza virus, a sequential immunization method for stimulating a patient's immune system to induce protection against multiple pathogens, immunogenic composition to evoke an immune response against parainfluenza virus, isolated polynucleotide and expression vector - Google Patents
Parainfluenza virus, methods for stimulating a patient's immune system to induce protection against parainfluenza virus and for producing a particle of parainfluenza virus, a sequential immunization method for stimulating a patient's immune system to induce protection against multiple pathogens, immunogenic composition to evoke an immune response against parainfluenza virus, isolated polynucleotide and expression vectorInfo
- Publication number
- BR0105530A BR0105530A BR0105530-5A BR0105530A BR0105530A BR 0105530 A BR0105530 A BR 0105530A BR 0105530 A BR0105530 A BR 0105530A BR 0105530 A BR0105530 A BR 0105530A
- Authority
- BR
- Brazil
- Prior art keywords
- piv
- parainfluenza virus
- chimeric
- stimulating
- patient
- Prior art date
Links
Abstract
"VìRUS DA PARAINFLUENZA, MéTODOS PARA ESTIMULAR O SISTEMA IMUNE DE UM PACIENTE PARA INDUZIR PROTEçãO CONTRA O VìRUS DA PARAINFLUENZA E PARA PRODUZIR UMA PARTìCULA DE VìRUS DA PARAINFLUENZA, MéTODO DE IMUNIZAçãO SEQuENCIAL PARA ESTIMULAR O SISTEMA IMUNE DE UM PACIENTE A INDUZIR PROTEçãO CONTRA PATóGENOS MúLTIPLOS, COMPOSIçãO IMUNOGêNICA PARA EVOCAR UMA RESPOSTA IMUNE CONTRA O VìRUS DA PARAINFLUENZA, POLINUCLEOTìDEO ISOLADO E VETOR DE EXPRESSãO". Os vírus da parainfluenza quiméricos (PIVs) são fornecidos os quais incorporam um genoma ou antigenoma de vetor PIV e um ou mais determinantes antigênicos de um patógeno PIV ou não PIV heterólogo. Estes vírus quiméricos são infecciosos e atenuados em seres humanos e outros mamíferos e são úteis em formulações de vacina para evocar uma resposta imune contra um ou mais PIVs ou contra patógenos PIV e não PIV. Também são fornecidas moléculas de polinucleotídeos isoladas e vetores que incorporam um genoma ou antigenoma de PIV quiméricos que incluem um genoma ou antigenoma de vetor PIV parciais ou completos combinados ou integrados com um ou mais genes heterólogos ou segmentos de genoma que codificam determinantes antigênicos de um patógeno PIV ou não PIV heterólogo. Em aspectos preferidos da invenção, o PIV quimérico incorpora um genoma ou antigenoma de vetor de PIV, parciais ou completos, humanos, bovinos ou humanos-bovinos quiméricos combinados com um ou mais genes heterólogos ou segmentos de genoma de um patógeno de PIV ou não PIV heterólogo, em que o vírus quimérico é atenuado para o uso como um agente de vacina por qualquer uma de uma variedade de mutações e modificações de nucleotídeo introduzidas no genoma ou antigenoma quiméricos."PARINFLUENZA VIRUSES, METHODS FOR STIMULATING A PATIENT'S IMMUNE SYSTEM TO INDUCE PROTECTION AGAINST PARINFLUENZA VIRUSES AND TO PRODUCE A PARINICUTE OF IMPLEMENTATION OF THE PARINFLUENZA VIRUSES , IMMUNOGENIC COMPOSITION TO EVOCATE AN IMMUNE RESPONSE AGAINST PARINFLUENZA VIRUS, ISOLATED POLINUCLEOTIDE AND EXPRESSION VECTOR ". Chimeric parainfluenza viruses (PIVs) are provided which incorporate a PIV vector genome or antigen and one or more antigenic determinants of a heterologous PIV or non-PIV pathogen. These chimeric viruses are infectious and attenuated in humans and other mammals and are useful in vaccine formulations for eliciting an immune response against one or more PIVs or against PIV and non-PIV pathogens. Isolated polynucleotide molecules and vectors incorporating a chimeric PIV genome or antigenome that include a partial or complete PIV vector genome or antigen combined or integrated with one or more heterologous genes or genome segments encoding antigenic determinants of a pathogen are also provided. PIV or not heterologous PIV. In preferred aspects of the invention, the chimeric PIV incorporates a chimeric human, bovine or human-bovine partial or complete PIV vector genome or antigen combined with one or more heterologous genes or genome segments of a PIV or non-PIV pathogen heterologous, wherein the chimeric virus is attenuated for use as a vaccine agent by any of a variety of nucleotide mutations and modifications introduced into the chimeric genome or antigenome.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR0105530-5A BR0105530A (en) | 2001-11-28 | 2001-11-28 | Parainfluenza virus, methods for stimulating a patient's immune system to induce protection against parainfluenza virus and for producing a particle of parainfluenza virus, a sequential immunization method for stimulating a patient's immune system to induce protection against multiple pathogens, immunogenic composition to evoke an immune response against parainfluenza virus, isolated polynucleotide and expression vector |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR0105530-5A BR0105530A (en) | 2001-11-28 | 2001-11-28 | Parainfluenza virus, methods for stimulating a patient's immune system to induce protection against parainfluenza virus and for producing a particle of parainfluenza virus, a sequential immunization method for stimulating a patient's immune system to induce protection against multiple pathogens, immunogenic composition to evoke an immune response against parainfluenza virus, isolated polynucleotide and expression vector |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0105530A true BR0105530A (en) | 2003-09-09 |
Family
ID=27768059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0105530-5A BR0105530A (en) | 2001-11-28 | 2001-11-28 | Parainfluenza virus, methods for stimulating a patient's immune system to induce protection against parainfluenza virus and for producing a particle of parainfluenza virus, a sequential immunization method for stimulating a patient's immune system to induce protection against multiple pathogens, immunogenic composition to evoke an immune response against parainfluenza virus, isolated polynucleotide and expression vector |
Country Status (1)
| Country | Link |
|---|---|
| BR (1) | BR0105530A (en) |
-
2001
- 2001-11-28 BR BR0105530-5A patent/BR0105530A/en not_active Application Discontinuation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Alu et al. | Intranasal COVID-19 vaccines: From bench to bed | |
| WO2005116270A3 (en) | Influenza virus vaccine composition and method of use | |
| WO2001042445A3 (en) | USE OF RECOMBINANT PARAINFLUENZA VIRUSES (PIVs) AS VECTORS TO PROTECT AGAINST INFECTION AND DISEASE CAUSED BY PIV AND OTHER HUMAN PATHOGENS | |
| DE60041280D1 (en) | CHIMERIC HUMAN CATTLE RESPIRATORY SYNCYTIAL VIRUS VACCINES | |
| FI102382B1 (en) | Expression system for chimeric glycoproteins containing immunogenic fragments of human respiratory syncytial virus glycoproteins | |
| WO2003072719A3 (en) | Metapneumovirus strains and their use in vaccine formulations and as vector for expression of antigenic sequences | |
| ATE499113T1 (en) | INFLUENZA VIRUS VACCINE COMPOSITION | |
| JP2014520117A5 (en) | ||
| BRPI0414381A (en) | adjuvant composition, immunogenic composition (s), vaccine composition, process for the manufacture of an immunogenic composition, pharmaceutical composition (s), kit, methods for treating a patient suffering from, or susceptible to, a tumor, to enhance a mammalian immune response to an antigen and to elicit a mammalian immune response against a disease state, uses an imidazoquinoline or derivative thereof and gm-csf and components | |
| CY1111167T1 (en) | CHEMICAL INFECTION CLINES OF SWINE CIRCULATION AND USE OF THESE | |
| WO2004096993A3 (en) | Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences and methods for propagating virus | |
| BRPI0816134A2 (en) | Herpesvirus, DNA sequence, vector, cell, virus, method for producing infectious particles, infectious particles, vaccine, use of herpesvirus or DNA sequence or vector or infectious particles, and method for preventive and / or treatment. treatment of a disease. | |
| PH12019500592A1 (en) | New swine influenza vaccine | |
| MXPA01013302A (en) | Attenuated human-bovine chimeric parainfluenza virus (piv) vaccines. | |
| PH12018500305A1 (en) | Multivalent vlp conjugates | |
| BRPI0419023A (en) | inactivated polio vaccine derived from the genus sabin of poliovirus | |
| Morçӧl et al. | Calcium phosphate nanoparticle (CaPNP) for dose-sparing of inactivated whole virus pandemic influenza A (H1N1) 2009 vaccine in mice | |
| WO2015138471A1 (en) | Heat inactivated poxvirus improves vaccination results | |
| AU2017261706A1 (en) | Inactivating pathogens and producing highly immunogenic inactivated vaccines using a dual oxidation process | |
| Morcol et al. | Influenza A (H5N1) virus subunit vaccine administered with CaPNP adjuvant induce high virus neutralization antibody titers in mice | |
| Reina | The new generation of messenger RNA (mRNA) vaccines against influenza | |
| BR0105530A (en) | Parainfluenza virus, methods for stimulating a patient's immune system to induce protection against parainfluenza virus and for producing a particle of parainfluenza virus, a sequential immunization method for stimulating a patient's immune system to induce protection against multiple pathogens, immunogenic composition to evoke an immune response against parainfluenza virus, isolated polynucleotide and expression vector | |
| BR112023021812A2 (en) | ADJUVANT VACCINE COMPOSITION AND METHODS | |
| Dehari et al. | RNA-Based Vaccines for Infectious Disease | |
| Banerji et al. | RNA vaccines: the evolution, applications, and the challenges ahead |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according art. 34 industrial property law | ||
| B07A | Technical examination (opinion): publication of technical examination (opinion) | ||
| B09B | Decision: refusal |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM ART. 8O COMBINADO COM ART. 11 DA LPI. |
|
| B09B | Decision: refusal |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |