BR0104357A - Uso de receptores de toxina gbs ou fragmentos imunogênicos dela para prevenir uma condição patoangiogênica em um mamìfero - Google Patents
Uso de receptores de toxina gbs ou fragmentos imunogênicos dela para prevenir uma condição patoangiogênica em um mamìferoInfo
- Publication number
- BR0104357A BR0104357A BR0104357-9A BR0104357A BR0104357A BR 0104357 A BR0104357 A BR 0104357A BR 0104357 A BR0104357 A BR 0104357A BR 0104357 A BR0104357 A BR 0104357A
- Authority
- BR
- Brazil
- Prior art keywords
- gbs toxin
- patoangiogenic
- prevent
- gbs
- condition
- Prior art date
Links
- 239000003053 toxin Substances 0.000 title abstract 8
- 231100000765 toxin Toxicity 0.000 title abstract 8
- 108700012359 toxins Proteins 0.000 title abstract 8
- 239000012634 fragment Substances 0.000 title abstract 3
- 230000002163 immunogen Effects 0.000 title abstract 3
- 241000124008 Mammalia Species 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464402—Receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Zoology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
Abstract
"USO DE RECEPTORES DE TOXINA GBS OU FRAGMENTOS IMUNOGêNICOS DELA PARA PREVENIR UMA CONDIçãO PATOANGIOGêNICA EM UM MAMìFERO". São propiciados métodos para evitar ou atenuar condições patoangiogênicas pela administração de pelo menos um polipeptídeo receptor de toxina GBS ou pelo menos um fragmento imunogênico daquela. São também propiciados uma composição que inclui um polipeptídeo receptor de toxina GBS e um método para fazer tal composição. Em outra modalidade da invenção, animais imunizados também recebem toxina GBS, anticorpos imunocompatíveis ao receptor de toxina GBS e/ou células T autologas expandidas ao receptor de toxina GBS. Métodos de identificação de receptores de toxina GBS adicionais são também incluidos nesta invenção.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17987000P | 2000-02-02 | 2000-02-02 | |
PCT/US2001/003662 WO2001056598A2 (en) | 2000-02-02 | 2001-02-02 | Methods for preventing or attenuating pathoangiogenic conditions by using gbs-toxin (cm101) |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0104357A true BR0104357A (pt) | 2002-05-21 |
Family
ID=22658332
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0104357-9A BR0104357A (pt) | 2000-02-02 | 2001-02-02 | Uso de receptores de toxina gbs ou fragmentos imunogênicos dela para prevenir uma condição patoangiogênica em um mamìfero |
Country Status (14)
Country | Link |
---|---|
US (1) | US20020061846A1 (pt) |
EP (1) | EP1198246B1 (pt) |
JP (1) | JP2003521523A (pt) |
KR (1) | KR20020001817A (pt) |
CN (1) | CN100400100C (pt) |
AT (1) | ATE465751T1 (pt) |
AU (2) | AU782853B2 (pt) |
BR (1) | BR0104357A (pt) |
CA (1) | CA2369050A1 (pt) |
DE (1) | DE60141938D1 (pt) |
IL (1) | IL145710A0 (pt) |
MX (1) | MXPA01009917A (pt) |
NO (1) | NO20014772L (pt) |
WO (1) | WO2001056598A2 (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8609614B2 (en) * | 1998-07-22 | 2013-12-17 | Vanderbilt University | GBS toxin receptor compositions and methods of use |
US6803448B1 (en) * | 1998-07-22 | 2004-10-12 | Vanderbilt University | GBS toxin receptor |
GB0227026D0 (en) * | 2002-11-20 | 2002-12-24 | Molecular Skincare Ltd | Psoriasis diagnostics and therapeutics |
ES2426288T3 (es) | 2003-10-15 | 2013-10-22 | Ube Industries, Ltd. | Novedoso derivado de imidazol |
WO2020209920A2 (en) * | 2019-01-25 | 2020-10-15 | Janssen Pharmaceutica Nv | Methods of mitigating toxic effects of vesicants and caustic gas |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
CA2016842A1 (en) | 1989-05-16 | 1990-11-16 | Richard A. Lerner | Method for tapping the immunological repertoire |
US5010062A (en) * | 1989-09-25 | 1991-04-23 | Vanderbilt University | Therapeutic agent and method of inhibiting vascularization of tumors |
US5858991A (en) * | 1997-01-29 | 1999-01-12 | Vanderbilt University | Facilitation of wound healing with CM101/GBS toxin |
US6803448B1 (en) * | 1998-07-22 | 2004-10-12 | Vanderbilt University | GBS toxin receptor |
DE69942767D1 (de) * | 1998-07-22 | 2010-10-28 | Univ Vanderbilt | Gbs toxin rezeptor |
-
2001
- 2001-02-02 JP JP2001556497A patent/JP2003521523A/ja active Pending
- 2001-02-02 BR BR0104357-9A patent/BR0104357A/pt not_active IP Right Cessation
- 2001-02-02 KR KR1020017012595A patent/KR20020001817A/ko not_active Application Discontinuation
- 2001-02-02 WO PCT/US2001/003662 patent/WO2001056598A2/en active Application Filing
- 2001-02-02 CA CA002369050A patent/CA2369050A1/en not_active Abandoned
- 2001-02-02 AT AT01906979T patent/ATE465751T1/de not_active IP Right Cessation
- 2001-02-02 IL IL14571001A patent/IL145710A0/xx unknown
- 2001-02-02 MX MXPA01009917A patent/MXPA01009917A/es unknown
- 2001-02-02 US US09/776,865 patent/US20020061846A1/en not_active Abandoned
- 2001-02-02 EP EP01906979A patent/EP1198246B1/en not_active Expired - Lifetime
- 2001-02-02 AU AU34817/01A patent/AU782853B2/en not_active Ceased
- 2001-02-02 DE DE60141938T patent/DE60141938D1/de not_active Expired - Lifetime
- 2001-02-02 CN CNB018005993A patent/CN100400100C/zh not_active Expired - Fee Related
- 2001-10-01 NO NO20014772A patent/NO20014772L/no unknown
-
2009
- 2009-10-16 AU AU2009227821A patent/AU2009227821A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
WO2001056598A3 (en) | 2002-02-14 |
CN100400100C (zh) | 2008-07-09 |
MXPA01009917A (es) | 2003-08-01 |
IL145710A0 (en) | 2002-07-25 |
US20020061846A1 (en) | 2002-05-23 |
ATE465751T1 (de) | 2010-05-15 |
CA2369050A1 (en) | 2001-08-09 |
WO2001056598A2 (en) | 2001-08-09 |
AU782853B2 (en) | 2005-09-01 |
JP2003521523A (ja) | 2003-07-15 |
EP1198246B1 (en) | 2010-04-28 |
KR20020001817A (ko) | 2002-01-09 |
NO20014772D0 (no) | 2001-10-01 |
NO20014772L (no) | 2001-11-12 |
EP1198246A2 (en) | 2002-04-24 |
AU3481701A (en) | 2001-08-14 |
AU2009227821A1 (en) | 2009-11-05 |
DE60141938D1 (de) | 2010-06-10 |
CN1372474A (zh) | 2002-10-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 8A., 9A., 10A. E 11A. ANUIDADE(S). |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2138 DE 27/12/2011. |