BR0017193A - Método baseado em computador para identificação de motivos de peptìdeo invariante conservado - Google Patents
Método baseado em computador para identificação de motivos de peptìdeo invariante conservadoInfo
- Publication number
- BR0017193A BR0017193A BR0017193-0A BR0017193A BR0017193A BR 0017193 A BR0017193 A BR 0017193A BR 0017193 A BR0017193 A BR 0017193A BR 0017193 A BR0017193 A BR 0017193A
- Authority
- BR
- Brazil
- Prior art keywords
- computer
- based method
- peptide motifs
- invariant peptide
- identifying
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
- G16B30/10—Sequence alignment; Homology search
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
- G16B35/10—Design of libraries
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
- G16C20/60—In silico combinatorial chemistry
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Evolutionary Biology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Library & Information Science (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Computing Systems (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
"MéTODO BASEADO EM COMPUTADOR PARA IDENTIFICAçãO DE MOTIVOS DE PEPTìDEO INVARIANTE CONSERVADO". A presente invenção refere-se a um método baseado em computador para realização de comparação sensata de genoma de vários organismos, o dito método de computador envolve a criação de bibliotecas de peptídeo a partir de seq³ências de proteína de vários organismos e subseq³ente comparação levando à identificação de motivos de peptídeo invariante conservados, e para esta finalidade vários motivos de peptídeo invariante foram identificados através de comparação de seq³ência direta entre os vários organismos bacterianos e os genomas hospedeiros sem quaisquer suposições a priori, e o presente método é útil para identificação de alvos de drogas potenciais e pode servir como barreira de droga para antibacterianos de amplo espectro bem como para diagnóstico específico de infecções, e, em adição, para determinação da função de proteínas de funções ainda desconhecidas com a ajuda de tais sinais de motivos de peptídeo invariantes.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/539,032 US7657378B1 (en) | 2000-03-30 | 2000-03-30 | Computer based method for identifying peptides useful as drug targets |
| PCT/IN2000/000085 WO2001074130A2 (en) | 2000-03-30 | 2000-08-31 | A computer based method for identifying conserved invariant peptide motifs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0017193A true BR0017193A (pt) | 2003-01-14 |
Family
ID=24149472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0017193-0A BR0017193A (pt) | 2000-03-30 | 2000-08-31 | Método baseado em computador para identificação de motivos de peptìdeo invariante conservado |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7657378B1 (pt) |
| EP (1) | EP1268512B1 (pt) |
| JP (1) | JP2003528639A (pt) |
| KR (1) | KR100780874B1 (pt) |
| CN (1) | CN1211398C (pt) |
| AU (1) | AU2001228793A1 (pt) |
| BR (1) | BR0017193A (pt) |
| CA (1) | CA2376710A1 (pt) |
| CZ (1) | CZ200232A3 (pt) |
| DE (1) | DE60017471T2 (pt) |
| HU (1) | HU228447B1 (pt) |
| IL (1) | IL147435A0 (pt) |
| RU (1) | RU2249044C2 (pt) |
| WO (1) | WO2001074130A2 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005057464A1 (en) * | 2003-12-05 | 2005-06-23 | Council Of Scientific And Industrial Research | A computer based versatile method for identifying protein coding dna sequences useful as drug targets |
| US8165823B2 (en) | 2005-07-15 | 2012-04-24 | Novartis Ag | Pamps, pathogen associated molecular patterns |
| BRPI0708912B8 (pt) * | 2006-03-14 | 2021-07-27 | Univ Oregon Health & Science | métodos in vitro para detecção de mycobacterium tuberculosis e de células t expressando cd8 que especificamente reconhecem seq id no: 11 em um indivíduo |
| EP3373950B1 (en) | 2015-11-11 | 2024-05-01 | Serimmune Inc. | Methods and compositions for assessing antibody specificities |
| GB202101078D0 (en) * | 2021-01-27 | 2021-03-10 | Oxford Immunotec Ltd | Fragment pools |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999050770A1 (en) * | 1998-03-27 | 1999-10-07 | Combichem, Inc. | Method and system for search of implicitly described virtual libraries |
-
2000
- 2000-03-30 US US09/539,032 patent/US7657378B1/en not_active Expired - Fee Related
- 2000-08-31 EP EP00993858A patent/EP1268512B1/en not_active Expired - Lifetime
- 2000-08-31 BR BR0017193-0A patent/BR0017193A/pt not_active Application Discontinuation
- 2000-08-31 IL IL14743500A patent/IL147435A0/xx active IP Right Grant
- 2000-08-31 CZ CZ200232A patent/CZ200232A3/cs unknown
- 2000-08-31 HU HU0204426A patent/HU228447B1/hu not_active IP Right Cessation
- 2000-08-31 JP JP2001571896A patent/JP2003528639A/ja active Pending
- 2000-08-31 CA CA002376710A patent/CA2376710A1/en not_active Abandoned
- 2000-08-31 CN CNB008195900A patent/CN1211398C/zh not_active Expired - Lifetime
- 2000-08-31 WO PCT/IN2000/000085 patent/WO2001074130A2/en active IP Right Grant
- 2000-08-31 RU RU2002103467/15A patent/RU2249044C2/ru active
- 2000-08-31 DE DE60017471T patent/DE60017471T2/de not_active Expired - Lifetime
- 2000-08-31 KR KR1020027000554A patent/KR100780874B1/ko active IP Right Grant
- 2000-08-31 AU AU2001228793A patent/AU2001228793A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0204426A2 (en) | 2003-05-28 |
| HU228447B1 (en) | 2013-03-28 |
| EP1268512B1 (en) | 2005-01-12 |
| EP1268512A2 (en) | 2003-01-02 |
| KR100780874B1 (ko) | 2007-11-29 |
| JP2003528639A (ja) | 2003-09-30 |
| US7657378B1 (en) | 2010-02-02 |
| WO2001074130A2 (en) | 2001-10-11 |
| KR20020097137A (ko) | 2002-12-31 |
| RU2249044C2 (ru) | 2005-03-27 |
| CA2376710A1 (en) | 2001-10-11 |
| DE60017471D1 (de) | 2005-02-17 |
| DE60017471T2 (de) | 2005-12-22 |
| IL147435A0 (en) | 2002-08-14 |
| WO2001074130A3 (en) | 2002-01-24 |
| CN1211398C (zh) | 2005-07-20 |
| HUP0204426A3 (en) | 2004-10-28 |
| CN1452631A (zh) | 2003-10-29 |
| AU2001228793A1 (en) | 2001-10-15 |
| CZ200232A3 (cs) | 2002-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Free format text: A CLASSIFICACAO ANTERIOR ERA: C07K 1/00 Ipc: G06F 19/22 (2011.01) |
|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] |
Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI. |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 25 DA LPI. |
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| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |