BR0014052A - Amine derivatives - Google Patents
Amine derivativesInfo
- Publication number
- BR0014052A BR0014052A BR0014052-0A BR0014052A BR0014052A BR 0014052 A BR0014052 A BR 0014052A BR 0014052 A BR0014052 A BR 0014052A BR 0014052 A BR0014052 A BR 0014052A
- Authority
- BR
- Brazil
- Prior art keywords
- amine derivatives
- ring
- solvates
- inhibition
- therapy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Immunology (AREA)
- Reproductive Health (AREA)
- Otolaryngology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Patente de Invenção: "DERIVADOS DE AMINAS". e seus sais e solvatos fisiologicamente aceitáveis, em que R^ 1^, R^ 2^, R^ 8^, R^ 9^, R^ 10^, R^ 11^, Q, X, Y, Z, r, o anel A e o anel C têm as definições estabelecidas na reivindicação 1, apresentam inibição de fosfodiesterase V e podem ser utilizados para tratar distúrbios do sistema cardiovascular e para o tratamento e/ou terapia da potência prejudicada.Invention Patent: "AMIN DERIVATIVES". and their physiologically acceptable salts and solvates, where R ^ 1 ^, R ^ 2 ^, R ^ 8 ^, R ^ 9 ^, R ^ 10 ^, R ^ 11 ^, Q, X, Y, Z, r, ring A and ring C have the definitions set out in claim 1, exhibit phosphodiesterase V inhibition and can be used to treat disorders of the cardiovascular system and for the treatment and / or therapy of impaired potency.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19944604A DE19944604A1 (en) | 1999-09-17 | 1999-09-17 | Amine derivatives |
PCT/EP2000/008256 WO2001021620A2 (en) | 1999-09-17 | 2000-08-24 | Amine derivatives of benzo-4,5-thieno-2,3-d pyrimidines |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0014052A true BR0014052A (en) | 2002-05-21 |
Family
ID=7922374
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0014052-0A BR0014052A (en) | 1999-09-17 | 2000-08-24 | Amine derivatives |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1212329A2 (en) |
JP (1) | JP2003509511A (en) |
KR (1) | KR20020027652A (en) |
AU (1) | AU7412700A (en) |
BR (1) | BR0014052A (en) |
CA (1) | CA2387520A1 (en) |
CZ (1) | CZ2002817A3 (en) |
DE (1) | DE19944604A1 (en) |
NO (1) | NO20021310D0 (en) |
PL (1) | PL353319A1 (en) |
WO (1) | WO2001021620A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10148883A1 (en) | 2001-10-04 | 2003-04-10 | Merck Patent Gmbh | New fused bi- or tricyclic pyrimidine derivatives, are phosphodiesterase V inhibitors useful e.g. for treating impotence, cardiovascular disorders, inflammation or tumors |
WO2003035653A1 (en) * | 2001-10-26 | 2003-05-01 | Nippon Soda Co.,Ltd. | Pyridothienopyrimidine compound and salt thereof |
AR059901A1 (en) | 2006-03-20 | 2008-05-07 | Bayer Pharmaceuticals Corp | USEFUL TETRAHYDROPIRIDOTIENOPIRIMIDINE COMPOUNDS TO TREAT OR PREVENT CELLULAR PROLIFERATIVE DISORDERS. |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1470356A1 (en) * | 1964-01-15 | 1970-04-30 | Thomae Gmbh Dr K | New thieno [3,2-d] pyrimidines and process for their preparation |
US5869486A (en) * | 1995-02-24 | 1999-02-09 | Ono Pharmaceutical Co., Ltd. | Fused pyrimidines and pyriazines as pharmaceutical compounds |
DE19644228A1 (en) * | 1996-10-24 | 1998-04-30 | Merck Patent Gmbh | Thienopyrimidines |
DE19819023A1 (en) * | 1998-04-29 | 1999-11-04 | Merck Patent Gmbh | Thienopyrimidines |
US5948911A (en) * | 1998-11-20 | 1999-09-07 | Cell Pathways, Inc. | Method for inhibiting neoplastic cells and related conditions by exposure to thienopyrimidine derivatives |
CN1346358A (en) * | 1999-03-30 | 2002-04-24 | 日本曹达株式会社 | Thienopyrimidine compounds and salts thereof and process for the preparation of the same |
DE19928146A1 (en) * | 1999-06-19 | 2000-12-21 | Merck Patent Gmbh | New 3-benzylamino-benzothienopyrimidine derivatives inhibit phosphodiesterase V and are useful for treating cardiac insufficiency and impotence |
-
1999
- 1999-09-17 DE DE19944604A patent/DE19944604A1/en not_active Withdrawn
-
2000
- 2000-08-24 WO PCT/EP2000/008256 patent/WO2001021620A2/en active Search and Examination
- 2000-08-24 KR KR1020027003415A patent/KR20020027652A/en not_active Application Discontinuation
- 2000-08-24 PL PL00353319A patent/PL353319A1/en unknown
- 2000-08-24 EP EP00962374A patent/EP1212329A2/en not_active Withdrawn
- 2000-08-24 AU AU74127/00A patent/AU7412700A/en not_active Abandoned
- 2000-08-24 CZ CZ2002817A patent/CZ2002817A3/en unknown
- 2000-08-24 BR BR0014052-0A patent/BR0014052A/en not_active Application Discontinuation
- 2000-08-24 CA CA002387520A patent/CA2387520A1/en not_active Abandoned
- 2000-08-24 JP JP2001524996A patent/JP2003509511A/en active Pending
-
2002
- 2002-03-15 NO NO20021310A patent/NO20021310D0/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO20021310L (en) | 2002-03-15 |
WO2001021620A2 (en) | 2001-03-29 |
AU7412700A (en) | 2001-04-24 |
KR20020027652A (en) | 2002-04-13 |
CZ2002817A3 (en) | 2002-06-12 |
DE19944604A1 (en) | 2001-03-22 |
PL353319A1 (en) | 2003-11-17 |
NO20021310D0 (en) | 2002-03-15 |
EP1212329A2 (en) | 2002-06-12 |
CA2387520A1 (en) | 2001-03-29 |
JP2003509511A (en) | 2003-03-11 |
WO2001021620A3 (en) | 2001-11-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |