BR0012984A - Method for treating a condition associated with mc4-r in a mammal, compound binding to mc4-r, and pharmaceutical composition - Google Patents

Method for treating a condition associated with mc4-r in a mammal, compound binding to mc4-r, and pharmaceutical composition

Info

Publication number
BR0012984A
BR0012984A BR0012984-4A BR0012984A BR0012984A BR 0012984 A BR0012984 A BR 0012984A BR 0012984 A BR0012984 A BR 0012984A BR 0012984 A BR0012984 A BR 0012984A
Authority
BR
Brazil
Prior art keywords
treating
pharmaceutical composition
mammal
condition associated
compound binding
Prior art date
Application number
BR0012984-4A
Other languages
Portuguese (pt)
Inventor
Martin P Maguire
Mingshi Dai
Tricia J Vos
Original Assignee
Millennium Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc
Publication of BR0012984A publication Critical patent/BR0012984A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"MéTODO PARA TRATAR UM ESTADO ASSOCIADO COM O MC4-R EM UM MAMìFERO, COMPOSTO DE LIGAçãO AO MC4-R, E, COMPOSIçãO FARMACêUTICA". Os compostos de ligação ao MC4-R da fórmula (I): B-Z-E em que B é uma porção de âncora, Z é uma porção centra e E é uma porção que interage com o MC4-R são debatidos. Os métodos de usar os compostos para tratar distúrbios associados com o MC4-R, tais como os distúrbios associados com a perda de peso, também são debatidos."METHOD FOR TREATING AN STATE ASSOCIATED WITH MC4-R IN A MAMMALIAN, COMPOUND OF CONNECTION TO MC4-R, AND, PHARMACEUTICAL COMPOSITION". The MC4-R binding compounds of formula (I): B-Z-E where B is an anchor portion, Z is a center portion and E is a portion that interacts with MC4-R are discussed. Methods of using the compounds to treat disorders associated with MC4-R, such as disorders associated with weight loss, are also debated.

BR0012984-4A 1999-08-04 2000-08-04 Method for treating a condition associated with mc4-r in a mammal, compound binding to mc4-r, and pharmaceutical composition BR0012984A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14728899P 1999-08-04 1999-08-04
US22327700P 2000-08-03 2000-08-03
PCT/US2000/021327 WO2001010842A2 (en) 1999-08-04 2000-08-04 Melanocortin-4 receptor binding compounds and methods of use thereof

Publications (1)

Publication Number Publication Date
BR0012984A true BR0012984A (en) 2002-07-16

Family

ID=26844785

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0012984-4A BR0012984A (en) 1999-08-04 2000-08-04 Method for treating a condition associated with mc4-r in a mammal, compound binding to mc4-r, and pharmaceutical composition

Country Status (7)

Country Link
EP (1) EP1204645A2 (en)
JP (1) JP2003528810A (en)
AU (1) AU6621600A (en)
BR (1) BR0012984A (en)
CA (1) CA2381008A1 (en)
MX (1) MXPA02001160A (en)
WO (1) WO2001010842A2 (en)

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Also Published As

Publication number Publication date
MXPA02001160A (en) 2002-07-02
JP2003528810A (en) 2003-09-30
EP1204645A2 (en) 2002-05-15
AU6621600A (en) 2001-03-05
CA2381008A1 (en) 2001-02-15
WO2001010842A2 (en) 2001-02-15
WO2001010842A3 (en) 2001-08-16

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