BR0011292A - Gene derived from lawsonia and related sodc proteins, peptides and polypeptides and their uses - Google Patents
Gene derived from lawsonia and related sodc proteins, peptides and polypeptides and their usesInfo
- Publication number
- BR0011292A BR0011292A BR0011292-5A BR0011292A BR0011292A BR 0011292 A BR0011292 A BR 0011292A BR 0011292 A BR0011292 A BR 0011292A BR 0011292 A BR0011292 A BR 0011292A
- Authority
- BR
- Brazil
- Prior art keywords
- lawsonia
- sodc
- peptides
- proteins
- present
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 6
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 241001469654 Lawsonia <weevil> Species 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 241001148567 Lawsonia intracellularis Species 0.000 abstract 3
- 241001465754 Metazoa Species 0.000 abstract 2
- 208000028774 intestinal disease Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 244000005700 microbiome Species 0.000 abstract 2
- 238000011321 prophylaxis Methods 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 230000004727 humoral immunity Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Abstract
Patente de Invenção: "GENE DERIVADO DE LAWSONIA E PROTEìNAS, PEPTìDEOS E POLIPEPTìDEOS SodC RELACIONADOS E SEUS USOS". A presente invenção refere-se geralmente a composições terapêuticas para o tratamento e/ou profilaxia de condições de doença intestinal em animais e pássaros causados ou exacerbados por Lawsonía intracellularis ou similar ou de outro modo microorganismos relacionados. Em particular, a presente invenção fornece um novo gene derivado de Lawsonia intracellularis que codifica um peptídeo, polipeptídeo ou proteína de SodC imunogênico que é particularmente útil como um antígeno em preparação de vacina para conferir imunidade humoral contra Lawsonia intracellularis e patógenos relacionados em hospedeiros animais. A presente invenção é também direcionada a métodos para o tratamento e/ou profilaxia de tais condições de doença intestinal e para agentes e procedimentos diagnósticos para detectar a Lawsonia intracellularis ou similar ou microorganismos de outro modo relacionados.Invention Patent: "LAWSONIA DERIVED GENE AND RELATED SodC PROTEINS, PEPTIDES AND POLYPEPTIMES AND THEIR USES". The present invention generally relates to therapeutic compositions for the treatment and / or prophylaxis of intestinal disease conditions in animals and birds caused or exacerbated by Lawsonía intracellularis or similar or otherwise related microorganisms. In particular, the present invention provides a new gene derived from Lawsonia intracellularis that encodes an immunogenic SodC peptide, polypeptide or protein that is particularly useful as an antigen in vaccine preparation to confer humoral immunity against Lawsonia intracellularis and related pathogens in animal hosts. The present invention is also directed to methods for the treatment and / or prophylaxis of such conditions of intestinal disease and to diagnostic agents and procedures for detecting Lawsonia intracellularis or similar or otherwise related microorganisms.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13398999P | 1999-05-13 | 1999-05-13 | |
| PCT/AU2000/000436 WO2000069903A1 (en) | 1999-05-13 | 2000-05-11 | LAWSONIA DERIVED GENE AND RELATED SodC POLYPEPTIDES, PEPTIDES AND PROTEINS AND THEIR USES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0011292A true BR0011292A (en) | 2002-02-26 |
Family
ID=22461256
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0011292-5A BR0011292A (en) | 1999-05-13 | 2000-05-11 | Gene derived from lawsonia and related sodc proteins, peptides and polypeptides and their uses |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1177212A4 (en) |
| JP (1) | JP2003501013A (en) |
| AR (1) | AR023975A1 (en) |
| AU (1) | AU4385800A (en) |
| BR (1) | BR0011292A (en) |
| CA (1) | CA2372095A1 (en) |
| MX (1) | MXPA01011670A (en) |
| NZ (1) | NZ515332A (en) |
| PE (1) | PE20010238A1 (en) |
| WO (1) | WO2000069903A1 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6605696B1 (en) | 1999-10-22 | 2003-08-12 | Pfizer, Inc. | Lawsonia intracellularis proteins, and related methods and materials |
| ES2266090T3 (en) | 2000-12-20 | 2007-03-01 | Intervet International Bv | VACCINE AGAINST LAWSONIA INTRACELLULARIS. |
| EP1664100B1 (en) | 2003-09-12 | 2009-12-02 | Intervet International BV | Lawsonia intracellularis subunit vaccine |
| ATE470673T1 (en) * | 2004-01-22 | 2010-06-15 | Intervet Int Bv | VACCINES CONTAINING LAWSONIAINTRACELLULAR SUBUNIT |
| US8834891B2 (en) | 2005-03-14 | 2014-09-16 | Boehringer Ingelheim Vetmedica, Inc. | Immunogenic compositions comprising Lawsonia intracellularis |
| US8398994B2 (en) | 2005-07-15 | 2013-03-19 | Boehringer Ingelheim Vetmedica, Inc. | Lawsonia vaccine and methods of use thereof |
| EP2859900A1 (en) | 2006-12-11 | 2015-04-15 | Boehringer Ingelheim Vetmedica, Inc. | Effective method of treatment of porcine circovirus and lawsonia intracellularis infections |
| CN111830257B (en) * | 2020-07-17 | 2023-10-24 | 南京农业大学 | Pig-derived lawsonia intracellularis IPMA antigen detection method and application thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5885823A (en) * | 1995-06-05 | 1999-03-23 | Nobl Laboratories, Inc. | Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents |
| DE69636228D1 (en) * | 1995-11-30 | 2006-07-20 | Agriculture Victoria Serv Pty | Therapeutic compositions for the treatment of Lawsonia intracellularis infections |
-
2000
- 2000-05-11 EP EP00924975A patent/EP1177212A4/en not_active Withdrawn
- 2000-05-11 WO PCT/AU2000/000436 patent/WO2000069903A1/en not_active Application Discontinuation
- 2000-05-11 BR BR0011292-5A patent/BR0011292A/en not_active IP Right Cessation
- 2000-05-11 CA CA002372095A patent/CA2372095A1/en not_active Abandoned
- 2000-05-11 AU AU43858/00A patent/AU4385800A/en not_active Abandoned
- 2000-05-11 NZ NZ515332A patent/NZ515332A/en unknown
- 2000-05-11 MX MXPA01011670A patent/MXPA01011670A/en unknown
- 2000-05-11 JP JP2000618319A patent/JP2003501013A/en active Pending
- 2000-05-12 PE PE2000000445A patent/PE20010238A1/en not_active Application Discontinuation
- 2000-05-12 AR ARP000102294A patent/AR023975A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PE20010238A1 (en) | 2001-03-03 |
| CA2372095A1 (en) | 2000-11-23 |
| AU4385800A (en) | 2000-12-05 |
| AR023975A1 (en) | 2002-09-04 |
| EP1177212A4 (en) | 2002-08-28 |
| MXPA01011670A (en) | 2003-10-14 |
| EP1177212A1 (en) | 2002-02-06 |
| WO2000069903A1 (en) | 2000-11-23 |
| JP2003501013A (en) | 2003-01-14 |
| NZ515332A (en) | 2004-01-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7O, 8O E 9O ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2008 DE 30/06/2009. |