BR0007921A - Process for preventing or reducing cardiovascular events associated with coronary intervention - Google Patents

Process for preventing or reducing cardiovascular events associated with coronary intervention

Info

Publication number
BR0007921A
BR0007921A BR0007921-9A BR0007921A BR0007921A BR 0007921 A BR0007921 A BR 0007921A BR 0007921 A BR0007921 A BR 0007921A BR 0007921 A BR0007921 A BR 0007921A
Authority
BR
Brazil
Prior art keywords
coronary intervention
events associated
cardiovascular events
preventing
reducing cardiovascular
Prior art date
Application number
BR0007921-9A
Other languages
Portuguese (pt)
Inventor
Jeffrey R Granett
Neil H Shusterman
David C U Prichard
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of BR0007921A publication Critical patent/BR0007921A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

"PROCESSO PARA PREVENçãO OU REDUçãO DE EVENTOS CARDIOVASCULARES ASSOCIADOS COM INTERVENçãO CORONáRIA". Esta invenção provê um processo para a prevenção ou redução de eventos cardiovasculares associados com intervenção coronária em um mamífero, particularmente um humano, que compreende administração ao sujeito ácido N-(3',4'dimetoxi cinamoil) antranílico (N-5') ou um seu sal farmaceuticamente aceitável em uma dose diária a partir de mais que 300mg a cerca de 1200mg por um período de tratamento de até 89 dias em associação com intervenção coronária."PROCESS FOR THE PREVENTION OR REDUCTION OF CARDIOVASCULAR EVENTS ASSOCIATED WITH CORONARY INTERVENTION". This invention provides a process for the prevention or reduction of cardiovascular events associated with coronary intervention in a mammal, particularly a human, which comprises administration to the subject N- (3 ', 4'dimethoxy cinnamoyl) anthranilic (N-5') or a pharmaceutically acceptable salt thereof in a daily dose from more than 300mg to about 1200mg for a treatment period of up to 89 days in association with coronary intervention.

BR0007921-9A 1999-02-03 2000-02-02 Process for preventing or reducing cardiovascular events associated with coronary intervention BR0007921A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11846299P 1999-02-03 1999-02-03
PCT/US2000/002622 WO2000045811A1 (en) 1999-02-03 2000-02-02 Method for the prevention or reduction of cariovascular events associated with coronary intervention

Publications (1)

Publication Number Publication Date
BR0007921A true BR0007921A (en) 2002-09-10

Family

ID=22378750

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0007921-9A BR0007921A (en) 1999-02-03 2000-02-02 Process for preventing or reducing cardiovascular events associated with coronary intervention

Country Status (17)

Country Link
EP (1) EP1171116A4 (en)
JP (1) JP2002536327A (en)
KR (1) KR20010101934A (en)
CN (1) CN1345237A (en)
AU (1) AU2636600A (en)
BR (1) BR0007921A (en)
CA (1) CA2361581A1 (en)
CO (1) CO5150206A1 (en)
HK (1) HK1045104A1 (en)
HU (1) HUP0200129A3 (en)
IL (1) IL144721A0 (en)
MX (1) MXPA01007835A (en)
NO (1) NO20013788L (en)
PL (1) PL351397A1 (en)
TR (1) TR200102245T2 (en)
WO (1) WO2000045811A1 (en)
ZA (1) ZA200106353B (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2617407B2 (en) * 1992-09-14 1997-06-04 キッセイ薬品工業株式会社 Preventive and therapeutic agent for intimal cell hyperproliferative disease
US5693337A (en) * 1994-07-13 1997-12-02 Wakamoto Pharmaceutical Co., Ltd. Stable lipid emulsion
KR19990044478A (en) * 1995-09-07 1999-06-25 간자와 무츠와 2-acylaminobenzamide derivatives and preventive and therapeutic agents for diseases caused by vascular endothelial hyperplasia
US6019104A (en) * 1996-12-30 2000-02-01 Kissei Pharmaceutical Co., Ltd. Method for the treatment or prevention of restenosis associated with coronary intervention

Also Published As

Publication number Publication date
KR20010101934A (en) 2001-11-15
EP1171116A1 (en) 2002-01-16
TR200102245T2 (en) 2002-05-21
PL351397A1 (en) 2003-04-07
CN1345237A (en) 2002-04-17
MXPA01007835A (en) 2002-04-24
NO20013788D0 (en) 2001-08-02
WO2000045811A1 (en) 2000-08-10
JP2002536327A (en) 2002-10-29
HUP0200129A2 (en) 2002-05-29
NO20013788L (en) 2001-09-28
HK1045104A1 (en) 2002-11-15
CA2361581A1 (en) 2000-08-10
AU2636600A (en) 2000-08-25
ZA200106353B (en) 2002-08-02
CO5150206A1 (en) 2002-04-29
EP1171116A4 (en) 2004-11-17
IL144721A0 (en) 2002-06-30
HUP0200129A3 (en) 2003-06-30

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]