BG60659B2 - Derivatives of 2-phenyl-2-/1hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl/ethylamine - Google Patents
Derivatives of 2-phenyl-2-/1hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl/ethylamine Download PDFInfo
- Publication number
- BG60659B2 BG60659B2 BG096615A BG9661592A BG60659B2 BG 60659 B2 BG60659 B2 BG 60659B2 BG 096615 A BG096615 A BG 096615A BG 9661592 A BG9661592 A BG 9661592A BG 60659 B2 BG60659 B2 BG 60659B2
- Authority
- BG
- Bulgaria
- Prior art keywords
- alkyl
- hydrogen
- derivatives
- hydroxycycloalk
- enyl
- Prior art date
Links
- QUSNBJAOOMFDIB-UHFFFAOYSA-N Ethylamine Chemical compound CCN QUSNBJAOOMFDIB-UHFFFAOYSA-N 0.000 title 2
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- -1 cyano- Chemical class 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Производните на хидроксициклоалканфенетиламина имат антидепресивно действие и са със структурна формула в която а означава остатъците , като пунктираната линия означава в даден случай ненаситена връзка; r1 означава водород или алкил; r2 алкил; r4 водород, алкил, формил или алканоил; r5 и r6 независимо един от друг, са водород, хидроксил, алкил, алкокси-, алканоилокси-, циано-, нитро-, алкилмеркапто-, амино-, алкиламино-, диалкиламино-, алканамидо-, халоген, трифлуорметил или взети заедно образуват метилендиокси остатък; r7 е водород или алкил и n приема стойности 0, 1, 2, 3 или 4. Изобретението се отнася и до техните фармацевтично приемливи соли. 32 претенцииDerivatives of hydroxycycloalkanephenethylamine have an antidepressant effect and have a structural formula in which a denotes the residues, and the dotted line denotes an unsaturated bond in a given case; r 1 is hydrogen or alkyl; r 2 alkyl; r4 is hydrogen, alkyl, formyl or alkanoyl; r5 and r6 are independently hydrogen, hydroxyl, alkyl, alkoxy-, alkanoyloxy-, cyano-, nitro-, alkylmercapto-, amino-, alkylamino-, dialkylamino-, alkanamido-, halogen, trifluoromethyl or taken together form methylenedioxy remainder; r 7 is hydrogen or alkyl and n takes the values 0, 1, 2, 3 or 4. The invention also relates to their pharmaceutically acceptable salts. 32 claims
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/545,701 US4535186A (en) | 1983-04-19 | 1983-10-26 | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG60659B2 true BG60659B2 (en) | 1995-11-30 |
Family
ID=24177213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG096615A BG60659B2 (en) | 1983-10-26 | 1992-07-15 | Derivatives of 2-phenyl-2-/1hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl/ethylamine |
Country Status (1)
| Country | Link |
|---|---|
| BG (1) | BG60659B2 (en) |
-
1992
- 1992-07-15 BG BG096615A patent/BG60659B2/en unknown
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