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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
This compound is known by the name of mianserine hydrochloride and finds application as an antidepressive and antihistamine agent in the medical practice. It is obtained at high yield rates and purity. The method comprises reacting 2-methyl-1,2,3,4,10,14b-hexahydro-dibenzo (c,f)-pyrazino (1,2-a)-azepine sulphate (mianserine sulphate) with calcium chloride at elevated temperatures in an aqueous medium, followed by hot isolation of the resulting calcium sulphate. This is followed by cooling the filtrate down to room temperature and isolating the crystallized mianserine hydrochloride.
BG9648592A1992-06-161992-06-16Process for preparing 2-methyl-1,2,3,4,10,14b-hexahydro-dibenzo (c,f)-pyrazino
BG51804A1
(en)
Process for preparing novel pyrrolo-benzimidazole derivatives, pyrrolo -benzoxazole derivatives and pyrrolo-benzthiazole derivatives and pharmaceutical compositions comprising the same