BG51589A1 - Method for the production of haemostatic layer material - Google Patents

Method for the production of haemostatic layer material

Info

Publication number
BG51589A1
BG51589A1 BG8532088A BG8532088A BG51589A1 BG 51589 A1 BG51589 A1 BG 51589A1 BG 8532088 A BG8532088 A BG 8532088A BG 8532088 A BG8532088 A BG 8532088A BG 51589 A1 BG51589 A1 BG 51589A1
Authority
BG
Bulgaria
Prior art keywords
degrees
temperature
lyophilization
production
layer material
Prior art date
Application number
BG8532088A
Inventor
Nikolaj B Vasilev
Emilija J Miladinova
Blaga S Lisheva
Velichka A Kavardzhikova
Original Assignee
Bg Min Na Narodnata Otbrana
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bg Min Na Narodnata Otbrana filed Critical Bg Min Na Narodnata Otbrana
Priority to BG8532088A priority Critical patent/BG51589A1/en
Publication of BG51589A1 publication Critical patent/BG51589A1/en

Links

Abstract

The method is applied in surgery upon conducting organ-conserving operations of parenchymic organs. It ensures high hemostatic and medical properties of the material, stability upon lyophilization, sterilization and enduring conservation. Fraction I-III following Konn of plasma proteins is solved in a buffer of pH 5.17-5.25 and is left to stay at a temperature between 4 to 8 degrees C, after which the liquid is filtrated. Later, the filtrate is pH-adjusted to 6.8-7.2. Then gelatine is added for an end concentration of 37 g/l and thrombin to an end concentration of 125 E/l. The so-derived foamy mass is poured onto a plate and cooled to a temperature of minus 20 degrees C. On the table, a polyamide antiseptic sheet is laid. There follows a 24-hour lyophilization to an end sheet temperature of 99 degrees C.
BG8532088A 1988-08-26 1988-08-26 Method for the production of haemostatic layer material BG51589A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BG8532088A BG51589A1 (en) 1988-08-26 1988-08-26 Method for the production of haemostatic layer material

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BG8532088A BG51589A1 (en) 1988-08-26 1988-08-26 Method for the production of haemostatic layer material

Publications (1)

Publication Number Publication Date
BG51589A1 true BG51589A1 (en) 1993-07-15

Family

ID=3920975

Family Applications (1)

Application Number Title Priority Date Filing Date
BG8532088A BG51589A1 (en) 1988-08-26 1988-08-26 Method for the production of haemostatic layer material

Country Status (1)

Country Link
BG (1) BG51589A1 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9724078B2 (en) 2013-06-21 2017-08-08 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
US9999703B2 (en) 2012-06-12 2018-06-19 Ferrosan Medical Devices A/S Dry haemostatic composition
US10111980B2 (en) 2013-12-11 2018-10-30 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
US11046818B2 (en) 2014-10-13 2021-06-29 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
US11801324B2 (en) 2018-05-09 2023-10-31 Ferrosan Medical Devices A/S Method for preparing a haemostatic composition

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9999703B2 (en) 2012-06-12 2018-06-19 Ferrosan Medical Devices A/S Dry haemostatic composition
US10799611B2 (en) 2012-06-12 2020-10-13 Ferrosan Medical Devices A/S Dry haemostatic composition
US9724078B2 (en) 2013-06-21 2017-08-08 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
US10595837B2 (en) 2013-06-21 2020-03-24 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
US10111980B2 (en) 2013-12-11 2018-10-30 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
US11103616B2 (en) 2013-12-11 2021-08-31 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
US11046818B2 (en) 2014-10-13 2021-06-29 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
US11801324B2 (en) 2018-05-09 2023-10-31 Ferrosan Medical Devices A/S Method for preparing a haemostatic composition

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