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Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms
(AREA)
Abstract
The compounds obtained are biologically active and may find application in therapeutic practices. They posses beta-blocking activity and low toxicity. They have the common formula, listed below:<IMAGE>where R is a cycloalkyl residue with 5 to 8 carbon atoms, and R1 is a lower alkyl residue with 3 or 4 carbon atoms, a cycloalkyl- or a phenyl residue. According to the method, 1-cycloalkyl-oxy-2,3-epoxypropanes with the below given common formula:<IMAGE>are reacted with alkyl- or arylisocyanates with the following common formula: R1NCO, where R and R1 are identical to the indicated above, in the presence of catalytic amounts of lithium bromide upon boiling the reaction mixture.
BG8852489A1989-05-191989-05-193- alkyl- 5- substituted- 2- oxazolidones and method for their preparation
BG48386A1
(en)