BG108956A - A process for the preparation of tablets from pharmaceutically active substances having unfavourable tabletting properties with a granulating liquid comprising macrocrystalline cellulose
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A process for the preparation of tablets from pharmaceutically active substances having unfavourable tabletting properties with a granulating liquid comprising macrocrystalline cellulose
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Application filed by Egis Gyogyszergyar Rt.filedCriticalEgis Gyogyszergyar Rt.
Priority to BG108956ApriorityCriticalpatent/BG108956A/en
Publication of BG108956ApublicationCriticalpatent/BG108956A/en
The invention relates to a process for the preparation of tablets that can be well compressed and have good mechanical strength from pharmaceutically active ingredient(s) having unfavourable tabletting properties. In the process of the invention a granulating liquid is used which is a suspension of 5-30% of microcrystalline cellulose - 90% of which have a particle size that is lower than 50 Sg(m)m, and the amount of the microcrystalline cellulose refers to the final tablet mass in water and/or ethanol and/or isopropanol, and said suspension may contain also a part of the ingredients of the granules in dissolved form.
BG108956A2004-11-292004-11-29A process for the preparation of tablets from pharmaceutically active substances having unfavourable tabletting properties with a granulating liquid comprising macrocrystalline cellulose
BG108956A
(en)
A process for the preparation of tablets from pharmaceutically active substances having unfavourable tabletting properties with a granulating liquid comprising macrocrystalline cellulose
A process for the preparation of tablets from pharmaceutically active substances having unfavourable tabletting properties with a granulating liquid comprising macrocrystalline cellulose
A process for the preparation of tablets from pharmaceutically active substances having unfavourable tabletting properties with a granulating liquid comprising macrocrystalline cellulose
A process for the preparation of tablets from pharmaceutically active substances having unfavourabletabletting properties with a granulating liquid c omprising microcrystalline cellulose
A process for the preparation of tablets from pharmaceutically active substances having unfavourable tabletting properties with a granulating liquid comprising macrocrystalline cellulose
Compressed solid dosage form manufacturing process well-suited for use with drugs of low aqueous solubility and compressed solid dosage forms made thereby