BG105644A - Method for the preparation of thiamulin - Google Patents

Method for the preparation of thiamulin

Info

Publication number
BG105644A
BG105644A BG105644A BG10564401A BG105644A BG 105644 A BG105644 A BG 105644A BG 105644 A BG105644 A BG 105644A BG 10564401 A BG10564401 A BG 10564401A BG 105644 A BG105644 A BG 105644A
Authority
BG
Bulgaria
Prior art keywords
thiamulin
preparation
reaction
alkaline
pleuromutilintoluenesulphonate
Prior art date
Application number
BG105644A
Other languages
Bulgarian (bg)
Other versions
BG65100B1 (en
Inventor
Антон НАКОВ
Николай СТОЯНОВ
Борислава НАКОВА
Мария РЯДКОВА
Ердуван ЧАУШЕВ
Original Assignee
"Биовет" Ад
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by "Биовет" Ад filed Critical "Биовет" Ад
Priority to BG105644A priority Critical patent/BG65100B1/en
Publication of BG105644A publication Critical patent/BG105644A/en
Publication of BG65100B1 publication Critical patent/BG65100B1/en

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The method for the preparation of thiamulin includes the reaction between different pleuromutilintoluenesulphonate and 2-diethylaminoethanethiol or its derivatives. The reaction by the method occurs in a homogenous medium of C1-C3 alkanols in the presence of alkaline hydroxides or salts of alkaline metals with the carbonic acid. The method can be applied in production, at comparable yields, and it eliminates any operation with metallic sodium and end product of high HPLC-purity is produced. 1 claim
BG105644A 2001-06-25 2001-06-25 Method for the preparation of thiamulin BG65100B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BG105644A BG65100B1 (en) 2001-06-25 2001-06-25 Method for the preparation of thiamulin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BG105644A BG65100B1 (en) 2001-06-25 2001-06-25 Method for the preparation of thiamulin

Publications (2)

Publication Number Publication Date
BG105644A true BG105644A (en) 2003-04-30
BG65100B1 BG65100B1 (en) 2007-02-28

Family

ID=3928426

Family Applications (1)

Application Number Title Priority Date Filing Date
BG105644A BG65100B1 (en) 2001-06-25 2001-06-25 Method for the preparation of thiamulin

Country Status (1)

Country Link
BG (1) BG65100B1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111574416A (en) * 2020-05-29 2020-08-25 新疆浙大阳光生物科技有限公司 Method for preparing tiamulin from isothiourea salt and pleuromutilin p-methylbenzenesulfonate
CN113735747A (en) * 2020-05-29 2021-12-03 新疆上昵生物科技有限公司 Method for producing tiamulin by using diethylaminoethanethiol synthetic solution

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103450060A (en) * 2012-05-29 2013-12-18 大英九合生物化工股份有限公司 Synthesis method of tiamulin
CN103819374A (en) * 2012-11-16 2014-05-28 张丽学 Process for synthesizing diethylaminoethyl mercaptide

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111574416A (en) * 2020-05-29 2020-08-25 新疆浙大阳光生物科技有限公司 Method for preparing tiamulin from isothiourea salt and pleuromutilin p-methylbenzenesulfonate
CN113735747A (en) * 2020-05-29 2021-12-03 新疆上昵生物科技有限公司 Method for producing tiamulin by using diethylaminoethanethiol synthetic solution
CN111574416B (en) * 2020-05-29 2024-05-03 新疆上昵生物科技有限公司 Method for preparing tiamulin from isothiourea salt and pleuromutilin p-toluenesulfonate

Also Published As

Publication number Publication date
BG65100B1 (en) 2007-02-28

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