BG105481A - Tricyclic pyrazole derivatives - Google Patents
Tricyclic pyrazole derivativesInfo
- Publication number
- BG105481A BG105481A BG105481A BG10548101A BG105481A BG 105481 A BG105481 A BG 105481A BG 105481 A BG105481 A BG 105481A BG 10548101 A BG10548101 A BG 10548101A BG 105481 A BG105481 A BG 105481A
- Authority
- BG
- Bulgaria
- Prior art keywords
- pyrazoles
- pyrazole derivatives
- tricyclic pyrazole
- tricyclic
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Abstract
The invention relates to certain 3-aryl or 3-heteroaryl pyrazoles with 4,5(3,4)-bicyclic ring fusion of formula which are inhibitors of protein kinase activity, of which some are novel compounds, to pharmaceutical compositions containing these pyrazoles and to processes for preparing these pyrazoles. 77 claims
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10746798P | 1998-11-06 | 1998-11-06 | |
PCT/US1999/026105 WO2000027822A2 (en) | 1998-11-06 | 1999-11-04 | Tricyclic pyrazole derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
BG105481A true BG105481A (en) | 2001-12-29 |
Family
ID=22316761
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG105481A BG105481A (en) | 1998-11-06 | 2001-04-27 | Tricyclic pyrazole derivatives |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP1127051A2 (en) |
JP (1) | JP2003517447A (en) |
KR (1) | KR20010086005A (en) |
CN (1) | CN1335836A (en) |
AU (1) | AU762992B2 (en) |
BG (1) | BG105481A (en) |
BR (1) | BR9915132A (en) |
CA (1) | CA2350235A1 (en) |
CZ (1) | CZ20011563A3 (en) |
HK (1) | HK1042895A1 (en) |
HU (1) | HUP0200310A3 (en) |
ID (1) | ID30132A (en) |
IL (1) | IL142584A0 (en) |
NO (1) | NO20012219L (en) |
PL (1) | PL348210A1 (en) |
SK (1) | SK5282001A3 (en) |
TR (1) | TR200102277T2 (en) |
WO (1) | WO2000027822A2 (en) |
ZA (1) | ZA200103610B (en) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6462036B1 (en) | 1998-11-06 | 2002-10-08 | Basf Aktiengesellschaft | Tricyclic pyrazole derivatives |
NZ514756A (en) * | 1999-03-26 | 2004-04-30 | Euro Celtique S | Aryl substituted pyrazoles, imidazoles, oxazoles, thiazoles and pyrroles, and the use thereof |
US6297238B1 (en) | 1999-04-06 | 2001-10-02 | Basf Aktiengesellschaft | Therapeutic agents |
CZ20013580A3 (en) * | 1999-04-06 | 2002-03-13 | Knoll Gmbh | Substituted 1,4-dihydroindeno[1,2-c]pyrazoles functioning as tyrosine kinase inhibitors |
US20040048844A1 (en) | 1999-10-20 | 2004-03-11 | Bristol-Myers Squibb Pharma Company | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents |
US6291504B1 (en) | 1999-10-20 | 2001-09-18 | Dupont Pharmaceuticals Company | Acylsemicarbazides and their uses |
AU2001253127A1 (en) | 2000-04-05 | 2001-10-23 | Zymogenetics Inc. | Soluble zalpha11 cytokine receptors |
WO2002008221A2 (en) | 2000-07-20 | 2002-01-31 | Neurogen Corporation | Capsaicin receptor ligands |
ATE295354T1 (en) | 2000-08-18 | 2005-05-15 | Agouron Pharma | HETEROCYCLIC HYDROXIMINO FLUORENES AND THEIR USE FOR INHIBITING PROTEIN KINASES |
US6849631B2 (en) | 2000-12-08 | 2005-02-01 | Bristol Myers Squibb Pharma Company | Semicarbazides and their uses |
AU2002341729A1 (en) | 2001-09-19 | 2003-04-01 | Pharmacia Corporation | Substituted pyrazolyl compounds for the treatment of inflammation |
WO2003027075A2 (en) * | 2001-09-19 | 2003-04-03 | Pharmacia Corporation | Substituted pyrazolyl benzenesulfamide compounds for the treatment of inflammation |
US20040127492A1 (en) * | 2002-02-19 | 2004-07-01 | Pharmacia Corporation | Cyclic pyrazoles for the inhibition of mitogen activated protein kinase-activated protein kinase-2 |
CA2516254A1 (en) * | 2003-02-17 | 2004-08-26 | Pharmacia Italia S.P.A. | Tetracyclic pyrazole derivatives as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them |
US7456169B2 (en) | 2003-02-27 | 2008-11-25 | Abbott Laboratories Inc. | Heterocyclic kinase inhibitors |
US7320986B2 (en) | 2003-03-07 | 2008-01-22 | Abbott Labortories | Fused tri and tetra-cyclic pyrazole kinase inhibitors |
MXPA05009576A (en) * | 2003-03-07 | 2005-12-12 | Abbott Lab | Fused tri and tetra-cyclic pyrazole kinase inhibitors. |
CA2521854C (en) * | 2003-04-07 | 2011-11-01 | Gpc Biotech, Inc. | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto |
AR045037A1 (en) | 2003-07-10 | 2005-10-12 | Aventis Pharma Sa | TETRAHIDRO-1H-PIRAZOLO [3,4-C] SUBSTITUTED PYRIDINS, COMPOSITIONS THAT CONTAIN THEM AND ITS USE. |
GB0326601D0 (en) * | 2003-11-14 | 2003-12-17 | Novartis Ag | Organic compounds |
CA2560691A1 (en) | 2004-03-24 | 2005-10-13 | Abbott Laboratories | Tricyclic pyrazole kinase inhibitors |
WO2005118543A1 (en) * | 2004-06-03 | 2005-12-15 | Ono Pharmaceutical Co., Ltd. | Kinase inhibitor and use thereof |
SI2343304T1 (en) | 2005-02-16 | 2015-08-31 | Anacor Pharmaceuticals, Inc. | Biocidal boronophthalide compounds |
EP1968581A4 (en) * | 2005-12-16 | 2009-05-27 | Genentech Inc | Tetracyclic kinase inhibitors |
EP1976536A4 (en) | 2005-12-30 | 2011-03-02 | Anacor Pharmaceuticals Inc | Boron-containing small molecules |
CN101420854B (en) * | 2006-02-16 | 2013-08-07 | 安纳考尔医药公司 | Boron-containing small molecules as anti-inflammatory agents |
BRPI0711358A2 (en) | 2006-05-09 | 2011-09-27 | Pfizer Prod Inc | cycloalkylamino acid derivatives and their pharmaceutical compositions |
RU2015109165A (en) | 2008-03-06 | 2015-11-10 | Анакор Фармасьютикалз, Инк. | WOODEN SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS |
EP2348863A4 (en) | 2008-09-04 | 2012-03-07 | Anacor Pharmaceuticals Inc | Boron-containing small molecules |
US8461336B2 (en) | 2008-09-04 | 2013-06-11 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
US9346834B2 (en) | 2009-10-20 | 2016-05-24 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as antiprotozoal agents |
US9216972B2 (en) | 2009-10-29 | 2015-12-22 | Bristol-Myers Squibb Company | Tricyclic heterocyclic compounds |
US8461134B2 (en) | 2009-11-11 | 2013-06-11 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
AP2012006482A0 (en) | 2010-03-19 | 2012-10-31 | Anacor Pharmacueticals Inc | Boron-containing small molecules as anti-protozoalagent |
SG10201507032YA (en) | 2010-09-07 | 2015-10-29 | Anacor Pharmaceuticals Inc | Benzoxaborole derivatives for treating bacterial infections |
US8853207B2 (en) | 2012-04-12 | 2014-10-07 | Development Center For Biotechnology | Heterocyclic pyrazole compounds, method for preparing the same and use thereof |
CN102675326B (en) * | 2012-04-26 | 2014-08-20 | 华东理工大学 | Preparation method of 3,4-dihydrobenzene benzopyran [3,4-c] pyrazole tricyclic compound |
US9475816B2 (en) | 2012-09-07 | 2016-10-25 | Takeda Pharmaceutical Company Limited | Substituted-1,4-dihydropyrazolo[4,3-b]indoles |
BR112016000869B1 (en) * | 2013-07-15 | 2021-07-06 | Basf Se | compost, agricultural composition, veterinary composition and uses of a compost |
WO2016113261A1 (en) * | 2015-01-13 | 2016-07-21 | Basf Se | Fused tricyclic compounds, compositions comprising these compounds and their use for con-trolling invertebrate pests |
CN105884828A (en) * | 2015-02-16 | 2016-08-24 | 上海迪诺医药科技有限公司 | Polycyclic compound, pharmaceutical composition and application thereof |
WO2018045149A1 (en) | 2016-09-02 | 2018-03-08 | Bristol-Myers Squibb Company | Substituted tricyclic heterocyclic compounds |
US11225470B2 (en) | 2016-11-28 | 2022-01-18 | Sumitomo Chemical Company, Limited | Tetrazolinone compounds and its use as pest control agents |
US11046646B2 (en) | 2017-08-09 | 2021-06-29 | Bristol-Myers Squibb Company | Alkylphenyl compounds |
US11059784B2 (en) | 2017-08-09 | 2021-07-13 | Bristol-Myers Squibb Company | Oxime ether compounds |
WO2021115560A1 (en) * | 2019-12-09 | 2021-06-17 | Rottapharm Biotech S.R.L. | New fyn and vegfr2 kinase inhibitors |
CN113773258B (en) * | 2020-06-09 | 2023-08-25 | 兰州大学 | Human LRRK2 protein small molecule inhibitor and application thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3843665A (en) * | 1973-04-11 | 1974-10-22 | Sandoz Ag | Process for preparing substituted indeno,naphtho and cyclohepta pyrazoles |
JPS60130521A (en) * | 1983-12-19 | 1985-07-12 | Morishita Seiyaku Kk | Anticancer agent |
AU706262B2 (en) * | 1995-10-23 | 1999-06-10 | Osteoscreen, Inc. | Compositions and methods for treating bone deficit conditions |
JP2001518502A (en) * | 1997-10-06 | 2001-10-16 | ビーエーエスエフ アクチェンゲゼルシャフト | Indeno [1,2-c] pyrazole derivatives for inhibiting tyrosine kinase activity |
PT1023063E (en) * | 1997-10-06 | 2004-02-27 | Abbott Gmbh & Co Kg | DERIVATIVES OF INDENO1,2-C | NAFTO- 1,2-C | -E BENZO-6,7 | CYCLE-HEPTA¬1,2-C | PYRAZOLE |
-
1999
- 1999-11-04 AU AU19091/00A patent/AU762992B2/en not_active Ceased
- 1999-11-04 SK SK528-2001A patent/SK5282001A3/en unknown
- 1999-11-04 HU HU0200310A patent/HUP0200310A3/en unknown
- 1999-11-04 EP EP99962700A patent/EP1127051A2/en not_active Withdrawn
- 1999-11-04 PL PL99348210A patent/PL348210A1/en not_active Application Discontinuation
- 1999-11-04 BR BR9915132-4A patent/BR9915132A/en not_active IP Right Cessation
- 1999-11-04 CN CN99814744A patent/CN1335836A/en active Pending
- 1999-11-04 CZ CZ20011563A patent/CZ20011563A3/en unknown
- 1999-11-04 CA CA002350235A patent/CA2350235A1/en not_active Abandoned
- 1999-11-04 IL IL14258499A patent/IL142584A0/en unknown
- 1999-11-04 JP JP2000581002A patent/JP2003517447A/en active Pending
- 1999-11-04 KR KR1020017005726A patent/KR20010086005A/en not_active Application Discontinuation
- 1999-11-04 TR TR2001/02277T patent/TR200102277T2/en unknown
- 1999-11-04 ID IDW00200101001A patent/ID30132A/en unknown
- 1999-11-04 WO PCT/US1999/026105 patent/WO2000027822A2/en not_active Application Discontinuation
-
2001
- 2001-04-27 BG BG105481A patent/BG105481A/en unknown
- 2001-05-04 NO NO20012219A patent/NO20012219L/en not_active Application Discontinuation
- 2001-05-04 ZA ZA200103610A patent/ZA200103610B/en unknown
-
2002
- 2002-05-31 HK HK02104091.8A patent/HK1042895A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20010086005A (en) | 2001-09-07 |
CA2350235A1 (en) | 2000-05-18 |
EP1127051A2 (en) | 2001-08-29 |
TR200102277T2 (en) | 2002-01-21 |
WO2000027822A3 (en) | 2000-08-10 |
JP2003517447A (en) | 2003-05-27 |
IL142584A0 (en) | 2002-03-10 |
CN1335836A (en) | 2002-02-13 |
HK1042895A1 (en) | 2002-08-30 |
AU762992B2 (en) | 2003-07-10 |
ZA200103610B (en) | 2002-09-23 |
AU1909100A (en) | 2000-05-29 |
NO20012219L (en) | 2001-06-13 |
PL348210A1 (en) | 2002-05-06 |
HUP0200310A3 (en) | 2002-12-28 |
BR9915132A (en) | 2001-08-07 |
CZ20011563A3 (en) | 2003-02-12 |
ID30132A (en) | 2001-11-08 |
WO2000027822A2 (en) | 2000-05-18 |
NO20012219D0 (en) | 2001-05-04 |
HUP0200310A2 (en) | 2002-11-28 |
SK5282001A3 (en) | 2002-01-07 |
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