BG103023A - Bronchodilatation medicamentous form - Google Patents
Bronchodilatation medicamentous formInfo
- Publication number
- BG103023A BG103023A BG103023A BG10302398A BG103023A BG 103023 A BG103023 A BG 103023A BG 103023 A BG103023 A BG 103023A BG 10302398 A BG10302398 A BG 10302398A BG 103023 A BG103023 A BG 103023A
- Authority
- BG
- Bulgaria
- Prior art keywords
- aminophilin
- release
- copolyvidon
- mannitol
- medicament
- Prior art date
Links
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to bronchodilatation medicamentous form based on 3,7-dimethyl-purin-2,6-dion in the form of an adjunctive compound and 1,2-ethanediamine (2:1) which with the name of aminophilin is applied in the medical practice as broncholithic agent and diueretic. It has simplified composition, the supplementary substances ensuring the necessary therapeutical plasma concentrations within 12 h by active substance release in stages without having the necessity of multiple administration of the medicament. The medicament can be either in the form of coated tablets containing 100 mg of aminophilin or tablets of extended release containing 350 mg of aminophilin in wt. ratios to the supplementary substances of 2.4:1 and 2.7:1, respectivelyl. The coated tablets contains, in mg: anhydrous aminophilin from 50 to 150, mannitol SD 200 from 10 to 40, colloid silicon dioxide from 0.5 to 4, copolyvidon VA-64 from 2 to 10, talcum powder from 2 to 8, magnesium stearate from 1 to 4 and ehtylcellulose No. 10 from 1.0 to 5.0 as a coating forming substance. The medicamentous form with extended time of release contains, in mg: anhydrous aminophilin from 200 to 400, hydroxypropylmethyl cellulose K100 M from 25 to 60 mannitol SD 200 from 10 to 40, microcrystal cellulose from 10 to 50, colloidal silicon dioxide from 1 to 6, copolyvidon VA-64 from 5 to 20, talcum powder from 5 to 15 and magnesium stearate from 2 to 6. 2 claims
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BG103023A BG63965B1 (en) | 1998-12-16 | 1998-12-16 | Bronchodilatation medicamentous form |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BG103023A BG63965B1 (en) | 1998-12-16 | 1998-12-16 | Bronchodilatation medicamentous form |
Publications (2)
Publication Number | Publication Date |
---|---|
BG103023A true BG103023A (en) | 2000-06-30 |
BG63965B1 BG63965B1 (en) | 2003-08-29 |
Family
ID=3927638
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG103023A BG63965B1 (en) | 1998-12-16 | 1998-12-16 | Bronchodilatation medicamentous form |
Country Status (1)
Country | Link |
---|---|
BG (1) | BG63965B1 (en) |
-
1998
- 1998-12-16 BG BG103023A patent/BG63965B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
BG63965B1 (en) | 2003-08-29 |
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