BG100932A - Method for the preparation of cellular cultural inactivated vaccine against fowl pest - Google Patents

Method for the preparation of cellular cultural inactivated vaccine against fowl pest

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Publication number
BG100932A
BG100932A BG100932A BG10093296A BG100932A BG 100932 A BG100932 A BG 100932A BG 100932 A BG100932 A BG 100932A BG 10093296 A BG10093296 A BG 10093296A BG 100932 A BG100932 A BG 100932A
Authority
BG
Bulgaria
Prior art keywords
chicks
vaccine
cultural
preparation
infested
Prior art date
Application number
BG100932A
Other languages
Bulgarian (bg)
Inventor
Петко Петров
Георги ХАДЖИЕВ
Незабравка Джамбазова
Лучия Мукова
Васил МИНКОВ
Original Assignee
Научно-Изследов. Произв. Ветеринарно-Медицински Институт По Имунология
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Научно-Изследов. Произв. Ветеринарно-Медицински Институт По Имунология filed Critical Научно-Изследов. Произв. Ветеринарно-Медицински Институт По Имунология
Priority to BG100932A priority Critical patent/BG100932A/en
Publication of BG100932A publication Critical patent/BG100932A/en

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Abstract

The vaccine is inactivated by ethanol and is harmless. Theantigene for its preparation is produced after cultivation underroller conditions of the local cellular cultural strain DD/94 ofcells of the permanent line VIC21. The viral suspension producedwith infection titre 107.5 KID50 is adsorbed in 2% gel ofaliminium hydroxide and is settling for 48 h, after which thesupernatant is removed to 50% of the initial volume and isinactivated by ethanol. As an oleoadjuvant to the antigene mineraloil emulsified by montanide 888 is added in 3:2 ratio. Theimmunogeneity of the vaccine is tested on 18-20-week chicksimmunized with live vaccine in advance. On the 25th day after thevaccination a group of 10 chicks are infested by a virulent strainof the fowl pest virus. Simultaneoulsy a control group of 10unvaccined chicks is also infested. For 15 days 90% of thevaccined chicks remain in good health, and 90% of the controls diewith symptoms of fowl pest.2 claims.
BG100932A 1996-10-22 1996-10-22 Method for the preparation of cellular cultural inactivated vaccine against fowl pest BG100932A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BG100932A BG100932A (en) 1996-10-22 1996-10-22 Method for the preparation of cellular cultural inactivated vaccine against fowl pest

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BG100932A BG100932A (en) 1996-10-22 1996-10-22 Method for the preparation of cellular cultural inactivated vaccine against fowl pest

Publications (1)

Publication Number Publication Date
BG100932A true BG100932A (en) 1998-07-31

Family

ID=3926736

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100932A BG100932A (en) 1996-10-22 1996-10-22 Method for the preparation of cellular cultural inactivated vaccine against fowl pest

Country Status (1)

Country Link
BG (1) BG100932A (en)

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