BG100493A - Method for tylmycosine preparation - Google Patents

Method for tylmycosine preparation

Info

Publication number
BG100493A
BG100493A BG100493A BG10049396A BG100493A BG 100493 A BG100493 A BG 100493A BG 100493 A BG100493 A BG 100493A BG 10049396 A BG10049396 A BG 10049396A BG 100493 A BG100493 A BG 100493A
Authority
BG
Bulgaria
Prior art keywords
tylmycosine
strain
preparation
stageselection
nitrozoguanidin
Prior art date
Application number
BG100493A
Other languages
Bulgarian (bg)
Other versions
BG62353B1 (en
Inventor
Иван МУРГОВ
Запряна ДЕНКОВА
Original Assignee
"Протей-М-Иван Мургов" Ет
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by "Протей-М-Иван Мургов" Ет filed Critical "Протей-М-Иван Мургов" Ет
Priority to BG100493A priority Critical patent/BG62353B1/en
Publication of BG100493A publication Critical patent/BG100493A/en
Publication of BG62353B1 publication Critical patent/BG62353B1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

The invention relates to a method by which tylmycosine isprepared by the cultivation of strain Streptomyces hygroscopicusZM-8 registered in NBIMCC under No. 2413 produced by inducedmutagenesis with N-methyl-N-nitrozoguanidin on museum cultureStreptomyces hygroscopicus NRRL 3017 and subsequent stageselection. The process occurs under aerobic conditions innutritives containing sources of nitrogen, carbon and mineralsalts. The intermediate products 20-dihydro-20-hydroxymycosinesynthetized from the strain is chemically transformed by bindingto cis,3,5-dimethylpiperidine to forming tylmycosine which isseparated and purified.
BG100493A 1996-04-10 1996-04-10 Method for the preparation of tylmycosin BG62353B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BG100493A BG62353B1 (en) 1996-04-10 1996-04-10 Method for the preparation of tylmycosin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BG100493A BG62353B1 (en) 1996-04-10 1996-04-10 Method for the preparation of tylmycosin

Publications (2)

Publication Number Publication Date
BG100493A true BG100493A (en) 1997-12-30
BG62353B1 BG62353B1 (en) 1999-09-30

Family

ID=3926545

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100493A BG62353B1 (en) 1996-04-10 1996-04-10 Method for the preparation of tylmycosin

Country Status (1)

Country Link
BG (1) BG62353B1 (en)

Also Published As

Publication number Publication date
BG62353B1 (en) 1999-09-30

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