BE901727A - DERIVATIVES OF HEXAHYDROAZEPINO 3, 4-D IMIDAZOLES. - Google Patents

DERIVATIVES OF HEXAHYDROAZEPINO 3, 4-D IMIDAZOLES.

Info

Publication number
BE901727A
BE901727A BE0/214511A BE214511A BE901727A BE 901727 A BE901727 A BE 901727A BE 0/214511 A BE0/214511 A BE 0/214511A BE 214511 A BE214511 A BE 214511A BE 901727 A BE901727 A BE 901727A
Authority
BE
Belgium
Prior art keywords
hydrocarbon
acyclic
phenyl
hexahydroazepino
imidazoles
Prior art date
Application number
BE0/214511A
Other languages
French (fr)
Inventor
U Scarponi
L Bernardi
G Arcari
R Ceserani
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of BE901727A publication Critical patent/BE901727A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Dérivés de 1(3), 4, 5, 6, 7, 8- hexahydroazépino ( 3,4-d ) imidazoles exerçant une activité anti-ulcère et répondant à la formule I. R4= H, hydrocarbureacyclique en C1-C4, cycloakyle en C3-C6, benzyle, phényle, benzyle substitué, phényle substitué; R1 (sur N1 ou N3) = H, hydrocarbure acyclique en C1-C4, benzyle substitué; R2 et R3 = indépendamment H, hydrocarbure acyclique en C1-C4,phéyle, phényle substitué; X =O, S, NH, N-CN, N-SO2 C6 H4 CH3, N-COR6, CH-NO2, CH-SO2 R5; R5 = hydrocarbure acyclique en C1-C4, phényle substitué; R6 = hydrocarbure acyclique en C1-C4, cycloalkyle en C3-C6, phényle, phényle substitué.Derivatives of 1 (3), 4, 5, 6, 7, 8- hexahydroazepino (3,4-d) imidazoles exerting anti-ulcer activity and corresponding to formula I. R4 = H, C1-C4 cyclic hydrocarbon, cycloakyle C 3 -C 6, benzyl, phenyl, substituted benzyl, substituted phenyl; R1 (on N1 or N3) = H, C1-C4 acyclic hydrocarbon, substituted benzyl; R2 and R3 = independently H, acyclic C1-C4 hydrocarbon, pheyl, substituted phenyl; X = O, S, NH, N-CN, N-SO2 C6 H4 CH3, N-COR6, CH-NO2, CH-SO2 R5; R5 = acyclic C1-C4 hydrocarbon, substituted phenyl; R6 = C1-C4 acyclic hydrocarbon, C3-C6 cycloalkyl, phenyl, substituted phenyl.

BE0/214511A 1984-02-17 1985-02-13 DERIVATIVES OF HEXAHYDROAZEPINO 3, 4-D IMIDAZOLES. BE901727A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848404241A GB8404241D0 (en) 1984-02-17 1984-02-17 Hexahydroazepino (3 4-d)imidazole derivatives

Publications (1)

Publication Number Publication Date
BE901727A true BE901727A (en) 1985-05-29

Family

ID=10556766

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/214511A BE901727A (en) 1984-02-17 1985-02-13 DERIVATIVES OF HEXAHYDROAZEPINO 3, 4-D IMIDAZOLES.

Country Status (4)

Country Link
JP (1) JPS60184082A (en)
BE (1) BE901727A (en)
DE (1) DE3504711A1 (en)
GB (2) GB8404241D0 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2173187B (en) * 1985-03-23 1988-05-18 Erba Farmitalia Condensed 2-substituted thiazole derivatives
CN116147316A (en) * 2023-03-08 2023-05-23 恒天重工股份有限公司 Energy-saving system for preheating spunlaced nonwoven fabric by utilizing waste heat energy

Also Published As

Publication number Publication date
DE3504711A1 (en) 1985-08-22
GB8503218D0 (en) 1985-03-13
GB2152052B (en) 1987-05-07
GB8404241D0 (en) 1984-03-21
GB2152052A (en) 1985-07-31
JPS60184082A (en) 1985-09-19

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: FARMITALIA CARLO ERBA S.P.A.

Effective date: 19870228