BE900854A - DRUGS BASED ON 1,2-DITHIOLANE DERIVATIVES. - Google Patents

DRUGS BASED ON 1,2-DITHIOLANE DERIVATIVES.

Info

Publication number
BE900854A
BE900854A BE1/11125A BE1011125A BE900854A BE 900854 A BE900854 A BE 900854A BE 1/11125 A BE1/11125 A BE 1/11125A BE 1011125 A BE1011125 A BE 1011125A BE 900854 A BE900854 A BE 900854A
Authority
BE
Belgium
Prior art keywords
amino
drugs based
dithiolane
derivatives
dithiolane derivatives
Prior art date
Application number
BE1/11125A
Other languages
French (fr)
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Publication of BE900854A publication Critical patent/BE900854A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention a pour objet des dérivés du 1,2-dithiolanne, spécialement des composés de formule I dans laquelle R1 représente un groupe hydroxy, alcoxy inférieur, amino, cyclo-alkylamino ou mono-(alkyl inférieur)-amino ou di-(alkyl inférieur)-amino dans lesquels les restes alkyle sont non substitués par un groupe aryle, hétéroaryle ou cycloalkyle et n signifie un nombre entier compris entre 0 et 10. Ces composés exercent une activité immunostimulante.The subject of the invention is derivatives of 1,2-dithiolane, especially compounds of formula I in which R1 represents a hydroxy, lower alkoxy, amino, cyclo-alkylamino or mono- (lower alkyl) -amino or di- ( lower alkyl) -amino in which the alkyl radicals are unsubstituted by an aryl, heteroaryl or cycloalkyl group and n signifies an integer between 0 and 10. These compounds exert an immunostimulatory activity.

BE1/11125A 1983-10-24 1984-10-19 DRUGS BASED ON 1,2-DITHIOLANE DERIVATIVES. BE900854A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH5746/83A CH656382A5 (en) 1983-10-24 1983-10-24 SULFOXIDES, METHOD FOR THEIR PRODUCTION AND THEIR USE.

Publications (1)

Publication Number Publication Date
BE900854A true BE900854A (en) 1985-04-19

Family

ID=4298650

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1/11125A BE900854A (en) 1983-10-24 1984-10-19 DRUGS BASED ON 1,2-DITHIOLANE DERIVATIVES.

Country Status (19)

Country Link
JP (1) JPS60115574A (en)
AU (1) AU3454984A (en)
BE (1) BE900854A (en)
CH (1) CH656382A5 (en)
DE (1) DE3438585A1 (en)
DK (1) DK505684A (en)
ES (1) ES8601183A1 (en)
FI (1) FI844153L (en)
FR (1) FR2553663A1 (en)
GB (1) GB2148296A (en)
GR (1) GR80730B (en)
HU (1) HUT36823A (en)
IL (1) IL73278A0 (en)
IT (1) IT1199212B (en)
LU (1) LU85607A1 (en)
NL (1) NL8403083A (en)
PT (1) PT79389B (en)
SE (1) SE8405275L (en)
ZA (1) ZA848303B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE67874B1 (en) * 1989-11-09 1996-05-01 Asta Medica Ag Medicaments containing as active substance sulphur-containing carboxylic acids and their use in combating retroviruses
JPH05337004A (en) * 1992-06-09 1993-12-21 Gotoujiyuu:Kk Knapsack
JPH077521U (en) * 1993-07-13 1995-02-03 ナース鞄工株式会社 school bag
US5801195A (en) 1994-12-30 1998-09-01 Celgene Corporation Immunotherapeutic aryl amides
CA2260128A1 (en) * 1996-07-05 1998-01-15 William G. Rice Anti-viral pharmaceutical compositions containing saturated 1,2-dithiaheterocyclic compounds and uses thereof
CZ96798A3 (en) * 1997-04-02 1998-10-14 Sankyo Company Limited Dithiolan derivatives, process of their preparation and their therapeutic effects
JP2000169371A (en) * 1998-10-02 2000-06-20 Sankyo Co Ltd Medicament containing dithiolane derivative
FR2787109B1 (en) * 1998-12-15 2001-01-19 Adir NOVEL 1,2-DITHIOLANE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2933430A (en) * 1959-01-22 1960-04-19 Du Pont Lipoic acid compositions

Also Published As

Publication number Publication date
HUT36823A (en) 1985-10-28
ZA848303B (en) 1986-06-25
IL73278A0 (en) 1985-01-31
IT8449056A0 (en) 1984-10-24
FI844153L (en) 1985-04-25
CH656382A5 (en) 1986-06-30
DK505684A (en) 1985-04-25
NL8403083A (en) 1985-05-17
AU3454984A (en) 1985-05-02
ES537010A0 (en) 1985-11-01
LU85607A1 (en) 1985-06-19
GB2148296A (en) 1985-05-30
FI844153A0 (en) 1984-10-22
JPS60115574A (en) 1985-06-22
SE8405275D0 (en) 1984-10-22
SE8405275L (en) 1985-04-25
PT79389B (en) 1986-09-08
PT79389A (en) 1984-11-01
FR2553663A1 (en) 1985-04-26
IT8449056A1 (en) 1986-04-24
GB8426657D0 (en) 1984-11-28
DK505684D0 (en) 1984-10-23
DE3438585A1 (en) 1985-05-02
ES8601183A1 (en) 1985-11-01
IT1199212B (en) 1988-12-30
GR80730B (en) 1985-02-20

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SANDOZ S.A.

Effective date: 19861031