BE883995A - 1,9-dihydroxy-octahydro-benzo (c) quinoleines et 1-hydroxy-hexahydro-benzo (c) quinoleine-9 (8h)-ones a action anti-emetique - Google Patents

1,9-dihydroxy-octahydro-benzo (c) quinoleines et 1-hydroxy-hexahydro-benzo (c) quinoleine-9 (8h)-ones a action anti-emetique

Info

Publication number
BE883995A
BE883995A BE0/201166A BE201166A BE883995A BE 883995 A BE883995 A BE 883995A BE 0/201166 A BE0/201166 A BE 0/201166A BE 201166 A BE201166 A BE 201166A BE 883995 A BE883995 A BE 883995A
Authority
BE
Belgium
Prior art keywords
benzo
quinoleins
quinoleine
octahydro
hexahydro
Prior art date
Application number
BE0/201166A
Other languages
English (en)
Inventor
Milne G Mclean
M Johnson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BE883995A publication Critical patent/BE883995A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • C07D221/12—Phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
BE0/201166A 1979-06-26 1980-06-25 1,9-dihydroxy-octahydro-benzo (c) quinoleines et 1-hydroxy-hexahydro-benzo (c) quinoleine-9 (8h)-ones a action anti-emetique BE883995A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/052,324 US4228169A (en) 1979-06-26 1979-06-26 1,9-Dihydroxyoctahydrobenzo[c]quinolines and 1-hydroxyhexahydrobenzo[c]quinoline-9(8H)-ones as antiemetic agents

Publications (1)

Publication Number Publication Date
BE883995A true BE883995A (fr) 1980-12-29

Family

ID=21976860

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/201166A BE883995A (fr) 1979-06-26 1980-06-25 1,9-dihydroxy-octahydro-benzo (c) quinoleines et 1-hydroxy-hexahydro-benzo (c) quinoleine-9 (8h)-ones a action anti-emetique

Country Status (7)

Country Link
US (1) US4228169A (fr)
JP (1) JPS567718A (fr)
BE (1) BE883995A (fr)
DE (1) DE3023626A1 (fr)
IT (1) IT1150022B (fr)
PH (1) PH14827A (fr)
ZA (1) ZA803781B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4340737A (en) * 1979-05-29 1982-07-20 Pfizer Inc. 9-Hydroxyoctahydrobenzo[C]quinolines and intermediates therefor
US4405626A (en) * 1980-10-03 1983-09-20 Pfizer Inc. 9-Hydroxyoctahydrobenzo(c)quinolines analgesic compositions containing them and processes for producing analgesic with them
US4400385A (en) * 1980-10-03 1983-08-23 Pfizer Inc. 9-Hydroxyoctahydrobenzo [c]quinolines, analgesic compositions containing them and processes for producing analgesia with them
US4320124A (en) * 1980-10-17 1982-03-16 Pfizer Inc. Composition for enhancing binding of a benzodiazepine to central benzodiazepine receptors and use thereof
US4486428A (en) * 1982-03-16 1984-12-04 Pfizer Inc. Bicyclic benzo fused compounds
US4863934A (en) * 1982-03-16 1989-09-05 Pfizer Inc. Bicyclic benzo fused pyran compounds used for producing analgesia
US4870084A (en) * 1982-03-16 1989-09-26 Pfizer Inc. Bicyclic benzo fused pyran compounds used for nausea treatment and prevention
US4473704A (en) * 1982-03-16 1984-09-25 Pfizer Inc. Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4841078A (en) * 1982-03-16 1989-06-20 Pfizer Inc. Benzopyrans
US4920221A (en) * 1982-03-16 1990-04-24 Pfizer Inc. Substituted decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines
US4642373A (en) * 1982-03-16 1987-02-10 Pfizer Inc. Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4680404A (en) * 1983-01-13 1987-07-14 Pfizer Inc. Benzopyrans
US4943428A (en) * 1987-07-10 1990-07-24 Wright State University Stimulation of serotonin-1A receptors in mammals to alleviate motion sickness and emesis induced by chemical agents
US5863928A (en) 1993-11-19 1999-01-26 The Board Of Governors For Higher Education The State Of Rhode Island And Providence Plantation. Octahydrobenzo f!quinoline-based receptor agonists and antagonists
US5605906A (en) * 1995-03-24 1997-02-25 Merck Frosst Canada, Inc. Cannabinoid receptor agonists
WO2005115375A1 (fr) * 2004-05-25 2005-12-08 Othera Pharmaceuticals, Inc. Medicaments et promedicaments oculoselectifs
BRPI0514860A (pt) * 2004-09-02 2008-06-24 Wyeth Corp fenóis de fenantridina carbonila
IL292775A (en) 2019-11-08 2022-07-01 Vella Bioscience Inc preparations containing cannabidiol (cbd) that act peripherally and their use to improve female sexual function or to treat female sexual disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087545A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiemetic drugs
HU180917B (hu) 1976-05-17 1983-05-30 Pfizer Eljárás 5, 6, 6a, 7-tetrahidro-benzo [c] kinolin-9(8H)-on-származékok előállítására
SE7704749L (sv) * 1976-05-17 1977-12-05 Pfizer Kinoliner och forfarande och mellanprodukter for framstellning derav

Also Published As

Publication number Publication date
DE3023626A1 (de) 1981-01-08
ZA803781B (en) 1981-06-24
US4228169A (en) 1980-10-14
DE3023626C2 (fr) 1988-02-04
PH14827A (en) 1981-12-16
IT1150022B (it) 1986-12-10
IT8023058A0 (it) 1980-06-26
JPS567718A (en) 1981-01-27

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: PFIZER INC.

Effective date: 19950630