BE856735A - Oligosaccharides sulfates utiles notamment comme inhibiteurs du complement - Google Patents

Oligosaccharides sulfates utiles notamment comme inhibiteurs du complement

Info

Publication number
BE856735A
BE856735A BE179278A BE179278A BE856735A BE 856735 A BE856735 A BE 856735A BE 179278 A BE179278 A BE 179278A BE 179278 A BE179278 A BE 179278A BE 856735 A BE856735 A BE 856735A
Authority
BE
Belgium
Prior art keywords
oligosaccharides
complement inhibitors
sulphates
useful
sulphates useful
Prior art date
Application number
BE179278A
Other languages
English (en)
French (fr)
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of BE856735A publication Critical patent/BE856735A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
BE179278A 1976-07-12 1977-07-12 Oligosaccharides sulfates utiles notamment comme inhibiteurs du complement BE856735A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/704,584 US4021544A (en) 1976-07-12 1976-07-12 Complement inhibitors

Publications (1)

Publication Number Publication Date
BE856735A true BE856735A (fr) 1978-01-12

Family

ID=24830112

Family Applications (1)

Application Number Title Priority Date Filing Date
BE179278A BE856735A (fr) 1976-07-12 1977-07-12 Oligosaccharides sulfates utiles notamment comme inhibiteurs du complement

Country Status (13)

Country Link
US (1) US4021544A (xx)
JP (1) JPS539325A (xx)
AU (1) AU507327B2 (xx)
BE (1) BE856735A (xx)
DE (1) DE2730993A1 (xx)
FR (1) FR2358157A1 (xx)
GB (1) GB1553552A (xx)
IE (1) IE45524B1 (xx)
LU (1) LU77736A1 (xx)
NL (1) NL7707750A (xx)
PH (1) PH12008A (xx)
PT (1) PT66775B (xx)
ZA (1) ZA773544B (xx)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4221907A (en) * 1979-07-09 1980-09-09 American Cyanamid Company Substituted O-α-D and O-β-D-multi-galactopyranosyl and glucopyranosyl 1→4 and 1→6 galactopyranosyl 1→6 α-D-glucopyranoses
US4247535A (en) * 1979-11-05 1981-01-27 American Cyanamid Company Modified cyclodextrin sulfate salts as complement inhibitors
US4258180A (en) * 1979-11-05 1981-03-24 American Cyanamid Company C6-Modified cyclodextrin sulfate salts as complement inhibitors
US4342753A (en) * 1981-06-15 1982-08-03 American Cyanamid Company Carboxyalkyl derivatives of rutin poly(H-)sulfate
US4342752A (en) * 1981-06-15 1982-08-03 American Cyanamid Company Carbalkoxymethyl derivatives of rutin poly(H-)sulfate and method of use
US4359458A (en) * 1981-09-28 1982-11-16 American Cyanamid Company O-β. -D (and O-α.. -D) Multigalactopyranosyl, xylopyranosyl and glucopyranosyl sulfate salts
US4359459A (en) * 1981-09-28 1982-11-16 American Cyanamid Company O-α-D-Multigalactopyranosyl-O-α-D-multiglucopyranosyl-O-β-D
US4359460A (en) * 1981-10-13 1982-11-16 American Cyanamid Company 6'-(1-Adamantanecarboxylate)-6-O-α-D-galactopyranosyl-α-D-glucopyranose sulfate salts
US4359461A (en) * 1981-10-28 1982-11-16 American Cyanamid Company Mono-, di- and tri-adamantylcarbonyl- digalactopyranosyl- glucopyranosyl- fructofuranose sulfate salts
US4407796A (en) * 1981-12-28 1983-10-04 American Cyanamid Company Modulators of the complement system
US4404365A (en) * 1981-12-28 1983-09-13 American Cyanamid Company Modulators of the complement system
US4459293A (en) * 1981-12-28 1984-07-10 American Cyanamid Company Method of modulating the complement system by administering bis-[β-D-glucopyranosyl-1-thio (or sulfinyl or sulfonyl)]-aryline sulfate derivatives and the cation salts thereof
US4401661A (en) * 1982-04-16 1983-08-30 American Cyanamid Company N,N'-Bis(glucopyranosyl-D-glucopyranosyloxyphenyl)alkaline and methods of use
US4623539A (en) * 1983-02-04 1986-11-18 Tunc Deger C Nutrient barrier polysaccharide compositions and method of use
US4520017A (en) * 1983-02-04 1985-05-28 Tunc Deger C Method of reducing nutrient absorption
DE3331009A1 (de) * 1983-08-27 1985-03-14 Basf Ag, 6700 Ludwigshafen Verfahren zur erhoehung der enteralen resorbierbarkeit von heparin bzw. heparinoiden sowie das so erhaeltliche heparin- bzw. heparinoidpraeparat
US4916219A (en) * 1985-03-28 1990-04-10 University Of Iowa Research Foundation Oligosaccharide heparin fragments as inhibitors of complement cascade
JPS61227777A (ja) * 1985-04-02 1986-10-09 Showa Sangyo Kk ビフイズス菌生育活性剤
FR2584728B1 (fr) * 1985-07-12 1987-11-20 Choay Sa Procede de sulfatation de glycosaminoglycanes et de leurs fragments
US5908836A (en) * 1987-12-21 1999-06-01 Bar-Shalom; Daniel Protecting skin from radiation damage using sulphated sugars
US5709873A (en) * 1988-02-26 1998-01-20 Niels Bukh A/S Method of treating conditions of teeth and their supporting tissue
US5221616A (en) * 1988-07-15 1993-06-22 Quidel Corporation Prevention of spontaneous complement activation in mammalian biological fluids
DE3843572A1 (de) * 1988-12-23 1990-06-28 Henkel Kgaa Fliessfaehiges perlglanzkonzentrat
US5298616A (en) * 1990-10-03 1994-03-29 Hoffmann-La Roche Inc. Sulfated O-polysaccharide-trehaloses
US5705178A (en) * 1991-05-31 1998-01-06 Gliatech, Inc. Methods and compositions based on inhibition of cell invasion and fibrosis by anionic polymers
US5605938A (en) * 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
US5739115A (en) * 1993-10-07 1998-04-14 Glycomed Incorporated Sulfated maltooligosaccharides with heparin-like properties
EP0722326A4 (en) * 1993-10-07 1999-10-06 Glycomed Inc HIGHLY SULFATED MALTOOLIGOSSACCHARIDES WITH HEPARIN-LIKE PROPERTIES
US5783568A (en) * 1994-06-10 1998-07-21 Sugen, Inc. Methods for treating cancer and other cell proliferative diseases
AUPO556297A0 (en) * 1997-03-11 1997-04-10 Australian National University, The Sulfated oligosaccharides having anticoagulant/ antithrombotic activity
WO2006017726A2 (en) * 2004-08-05 2006-02-16 Ivax Drug Research Institute Ltd Polysulfated glycosides and salts thereof
EP3415153A1 (en) * 2012-01-30 2018-12-19 Baxalta GmbH Non-anticoagulant sulfated or sulfonated polysaccharides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2959583A (en) * 1959-01-23 1960-11-08 Warner Lambert Pharmaceutical Method of purifying sulfated polysaccharides
NL286444A (xx) * 1961-12-08
US3838150A (en) * 1971-07-06 1974-09-24 Maruko Pharmaceutical Co Disaccharide polysulfate ester hydroxyaluminum allantoinate-aluminum complex and process for preparing same
US3911915A (en) * 1972-09-05 1975-10-14 Einstein Coll Med Dialytic introduction of maltose into bloodstream
JPS5042019A (xx) * 1973-08-17 1975-04-16

Also Published As

Publication number Publication date
IE45524L (en) 1978-01-12
NL7707750A (nl) 1978-01-16
AU2623677A (en) 1979-01-04
PT66775B (en) 1978-12-15
GB1553552A (en) 1979-09-26
IE45524B1 (en) 1982-09-22
DE2730993A1 (de) 1978-01-19
JPS539325A (en) 1978-01-27
US4021544A (en) 1977-05-03
LU77736A1 (xx) 1977-10-14
FR2358157A1 (fr) 1978-02-10
PT66775A (en) 1977-08-01
PH12008A (en) 1978-10-06
AU507327B2 (en) 1980-02-14
ZA773544B (en) 1978-05-30

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