BE850203A - Nouveaux analogues de prostaglandines - Google Patents

Nouveaux analogues de prostaglandines

Info

Publication number
BE850203A
BE850203A BE173932A BE173932A BE850203A BE 850203 A BE850203 A BE 850203A BE 173932 A BE173932 A BE 173932A BE 173932 A BE173932 A BE 173932A BE 850203 A BE850203 A BE 850203A
Authority
BE
Belgium
Prior art keywords
prostaglandins
new analogues
analogues
new
Prior art date
Application number
BE173932A
Other languages
English (en)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of BE850203A publication Critical patent/BE850203A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/64—Acyl halides
    • C07C57/72—Acyl halides containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BE173932A 1976-01-08 1977-01-07 Nouveaux analogues de prostaglandines BE850203A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05647369 US4032576A (fr) 1976-01-08 1976-01-08

Publications (1)

Publication Number Publication Date
BE850203A true BE850203A (fr) 1977-07-07

Family

ID=24596720

Family Applications (1)

Application Number Title Priority Date Filing Date
BE173932A BE850203A (fr) 1976-01-08 1977-01-07 Nouveaux analogues de prostaglandines

Country Status (9)

Country Link
US (6) US4032576A (fr)
JP (1) JPS5948822B2 (fr)
AU (1) AU502672B2 (fr)
BE (1) BE850203A (fr)
CH (1) CH628316A5 (fr)
DE (1) DE2659216A1 (fr)
FR (1) FR2337714A1 (fr)
NL (1) NL7700116A (fr)
ZA (1) ZA767541B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4140708A (en) * 1975-10-16 1979-02-20 Hoffmann-La Roche Inc. Asymmetric synthesis of optically active prostaglandins
US4117014A (en) * 1976-01-09 1978-09-26 Abbott Laboratories Prostaglandin derivatives
US4229377A (en) * 1978-10-13 1980-10-21 The Upjohn Company 2-Decarboxy-2-hydroxymethyl-16-fluoro-PGE2 compounds
DE3121155A1 (de) * 1981-05-22 1982-12-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
EP0171441A1 (fr) * 1984-08-10 1986-02-19 Ono Pharmaceutical Co., Ltd. Analogues de prostaglandines, leurs préparations et leurs compositions
JPH0312489Y2 (fr) * 1985-09-13 1991-03-25
GB8625322D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Chemical compounds
TW197439B (fr) * 1991-04-04 1993-01-01 Ueno Pharmaceutics Applic Res Co Ltd
PT643051E (pt) * 1992-09-30 2000-06-30 R Tech Ueno Ltd Processo de producao de cetonas alfa,beta-insaturadas
US7851504B2 (en) * 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
EP2454227B1 (fr) 2009-07-13 2020-08-19 Patheon API Services Inc. Synthèse de prostanoïdes
CA2925927C (fr) 2013-09-30 2022-09-06 George Petros Yiannikouros Nouvelles voies de synthese pour des prostaglandines et des intermediaires de prostaglandine par metathese

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959346A (en) * 1969-03-14 1976-05-25 The Upjohn Company Racemic prostaglandins of the 2-series and analogs thereof
GB1334952A (en) * 1971-01-06 1973-10-24 Ici Ltd Cyclopentane derivat-ves and a process for their manufacture
DE2317019A1 (de) * 1972-04-27 1973-11-08 Upjohn Co Neue 4,5-didehydro-prostaglandine
US3933898A (en) * 1972-10-30 1976-01-20 The Upjohn Company PGE1 -oxa phenylene compounds
US3914282A (en) * 1973-01-16 1975-10-21 Upjohn Co Prostaglandin E{HD 1{B , F{HD 1{B , and A{HD 1 {B analogs
US3933892A (en) * 1973-02-12 1976-01-20 Hoffmann-La Roche Inc. Asymmetric synthesis of optically active prostaglandins
US3962293A (en) * 1973-07-20 1976-06-08 The Upjohn Company 13,14-Dihydro-16-fluoro prostaglandin F1
US3932463A (en) * 1974-06-03 1976-01-13 American Cyanamid Company 11-Deoxy-13-dihydro-prostaglandin-9-ketals

Also Published As

Publication number Publication date
FR2337714A1 (fr) 1977-08-05
USRE29926E (en) 1979-03-06
JPS5948822B2 (ja) 1984-11-29
NL7700116A (nl) 1977-07-12
US4139564A (en) 1979-02-13
ZA767541B (en) 1977-11-30
DE2659216A1 (de) 1977-07-21
US4032576A (fr) 1977-06-28
AU502672B2 (en) 1979-08-02
AU2067476A (en) 1978-06-22
US4097529A (en) 1978-06-27
US4088694A (en) 1978-05-09
FR2337714B1 (fr) 1983-05-20
JPS5289650A (en) 1977-07-27
CH628316A5 (de) 1982-02-26
US4088693A (en) 1978-05-09

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: THE UPJOHN CY

Effective date: 19860131