BE844513A - Procede de preparation de nicotinate de 4-(4'-chlorobenzyloxy) benzyle comme agent hypolipidemique - Google Patents
Procede de preparation de nicotinate de 4-(4'-chlorobenzyloxy) benzyle comme agent hypolipidemiqueInfo
- Publication number
- BE844513A BE844513A BE169235A BE169235A BE844513A BE 844513 A BE844513 A BE 844513A BE 169235 A BE169235 A BE 169235A BE 169235 A BE169235 A BE 169235A BE 844513 A BE844513 A BE 844513A
- Authority
- BE
- Belgium
- Prior art keywords
- chlorobenzyloxy
- preparation
- benzyl nicotinate
- hypolipidemic agent
- hypolipidemic
- Prior art date
Links
- VAOFYKUGDPBCRA-UHFFFAOYSA-N [4-[(4-chlorophenyl)methoxy]phenyl]methyl pyridine-3-carboxylate Chemical compound C1=CC(Cl)=CC=C1COC(C=C1)=CC=C1COC(=O)C1=CC=CN=C1 VAOFYKUGDPBCRA-UHFFFAOYSA-N 0.000 title 1
- 239000003524 antilipemic agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP50134445A JPS5259160A (en) | 1975-11-08 | 1975-11-08 | Preparation method of nicotinic acid44*44chlorobenzyloxy*benzyl ester |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE844513A true BE844513A (fr) | 1976-11-16 |
Family
ID=15128509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE169235A BE844513A (fr) | 1975-11-08 | 1976-07-26 | Procede de preparation de nicotinate de 4-(4'-chlorobenzyloxy) benzyle comme agent hypolipidemique |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4042594A (cs) |
| JP (1) | JPS5259160A (cs) |
| AR (1) | AR209667A1 (cs) |
| BE (1) | BE844513A (cs) |
| CA (1) | CA1051904A (cs) |
| DE (1) | DE2629918C3 (cs) |
| ES (1) | ES452186A1 (cs) |
| FR (1) | FR2330397A1 (cs) |
| SE (1) | SE428924B (cs) |
| SU (1) | SU650502A3 (cs) |
| ZA (1) | ZA764132B (cs) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4275068A (en) * | 1977-08-29 | 1981-06-23 | Siegfried Ag | Lipid lowering alkylene glycols and ester derivatives thereof |
| JPS57102866A (en) * | 1980-12-19 | 1982-06-26 | Kyorin Pharmaceut Co Ltd | Nicotinic acid derivative and its preparation |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1312775A (en) * | 1969-07-07 | 1973-04-04 | Mar Pha Etu Expl Marques | Aryloxyalkyl nicotinates |
| BE826867A (fr) * | 1974-11-20 | 1975-07-16 | Medicament hypolipidemiant et hydrocholesterolemiant |
-
1975
- 1975-11-08 JP JP50134445A patent/JPS5259160A/ja active Granted
-
1976
- 1976-06-30 SE SE7607473A patent/SE428924B/xx not_active IP Right Cessation
- 1976-06-30 US US05/701,015 patent/US4042594A/en not_active Expired - Lifetime
- 1976-07-02 DE DE2629918A patent/DE2629918C3/de not_active Expired
- 1976-07-06 FR FR7620577A patent/FR2330397A1/fr active Granted
- 1976-07-13 ZA ZA764132A patent/ZA764132B/xx unknown
- 1976-07-13 AR AR263936A patent/AR209667A1/es active
- 1976-07-26 SU SU762386211A patent/SU650502A3/ru active
- 1976-07-26 BE BE169235A patent/BE844513A/xx not_active IP Right Cessation
- 1976-08-16 CA CA259,125A patent/CA1051904A/en not_active Expired
- 1976-10-07 ES ES452186A patent/ES452186A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US4042594A (en) | 1977-08-16 |
| JPS5421345B2 (cs) | 1979-07-30 |
| ZA764132B (en) | 1977-06-29 |
| DE2629918A1 (de) | 1977-05-12 |
| AR209667A1 (es) | 1977-05-13 |
| ES452186A1 (es) | 1977-11-01 |
| FR2330397A1 (fr) | 1977-06-03 |
| FR2330397B1 (cs) | 1979-09-21 |
| SE7607473L (sv) | 1977-05-09 |
| JPS5259160A (en) | 1977-05-16 |
| AU1542976A (en) | 1978-01-05 |
| SU650502A3 (ru) | 1979-02-28 |
| DE2629918C3 (de) | 1979-01-25 |
| SE428924B (sv) | 1983-08-01 |
| CA1051904A (en) | 1979-04-03 |
| DE2629918B2 (de) | 1978-05-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: KYORIN PHARMACEUTICAL CO. LTD Effective date: 19910731 |