BE802709A - Nouveau produit actif pour le traitement de la leucemie a base d'acide n5 methiltetrahydrohomofulique ou des derives - Google Patents

Nouveau produit actif pour le traitement de la leucemie a base d'acide n5 methiltetrahydrohomofulique ou des derives

Info

Publication number
BE802709A
BE802709A BE133796A BE133796A BE802709A BE 802709 A BE802709 A BE 802709A BE 133796 A BE133796 A BE 133796A BE 133796 A BE133796 A BE 133796A BE 802709 A BE802709 A BE 802709A
Authority
BE
Belgium
Prior art keywords
methiltetrahydrohomofulic
derivatives
acid
treatment
new active
Prior art date
Application number
BE133796A
Other languages
English (en)
French (fr)
Inventor
J A R Mead
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Publication of BE802709A publication Critical patent/BE802709A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BE133796A 1972-07-24 1973-07-24 Nouveau produit actif pour le traitement de la leucemie a base d'acide n5 methiltetrahydrohomofulique ou des derives BE802709A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00274749A US3856959A (en) 1972-07-24 1972-07-24 Inhibition of leukemia utilizing 5-methyltetrahydrohomofolate

Publications (1)

Publication Number Publication Date
BE802709A true BE802709A (fr) 1973-11-16

Family

ID=23049461

Family Applications (1)

Application Number Title Priority Date Filing Date
BE133796A BE802709A (fr) 1972-07-24 1973-07-24 Nouveau produit actif pour le traitement de la leucemie a base d'acide n5 methiltetrahydrohomofulique ou des derives

Country Status (11)

Country Link
US (1) US3856959A (US07223432-20070529-C00017.png)
JP (1) JPS5541207B2 (US07223432-20070529-C00017.png)
AT (1) AT329312B (US07223432-20070529-C00017.png)
AU (1) AU476551B2 (US07223432-20070529-C00017.png)
BE (1) BE802709A (US07223432-20070529-C00017.png)
CA (1) CA1006093A (US07223432-20070529-C00017.png)
DE (1) DE2335898A1 (US07223432-20070529-C00017.png)
FR (1) FR2193608B1 (US07223432-20070529-C00017.png)
GB (1) GB1442772A (US07223432-20070529-C00017.png)
NL (1) NL7309977A (US07223432-20070529-C00017.png)
SE (1) SE431612B (US07223432-20070529-C00017.png)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1572137A (en) * 1977-02-22 1980-07-23 Bioresearch Sas Del Dr Livio C Stable compositions for therapeutic use based on d,1-5-methyltetrahydrofolic acid and its salts
US4927828A (en) * 1985-03-08 1990-05-22 The Trustees Of Princeton University Diastereoisomeric tetrahydropyrido-(2,3,d) pyrimidine derivatives
US4684653A (en) * 1985-03-08 1987-08-04 The Trustees Of Princeton University Pyrido(2,3-d)pyrimidine derivatives
US5026851A (en) * 1985-03-08 1991-06-25 The Trustees Of Princeton University Pyrido[2,3-]pyrimidine derivatives
US4833145A (en) * 1986-06-30 1989-05-23 The Trustees Of Princeton University 4(3H)-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine derivatives
US4902796A (en) * 1986-10-20 1990-02-20 The Trustees Of Princeton University 6-alkenyl and ethynyl derivatives of 2-amino-4-hydroxypyrido[2,3-d]pyrimidines
US4818819A (en) * 1986-10-20 1989-04-04 The Trustees Of Princeton University Process for the preparation of fused pyridine compounds
US5028608A (en) * 1989-12-11 1991-07-02 The Trustees Of Princeton University N-(6-Amino-(pyrrolo(2,3-d)pyrimidin-3-ylacyl) )-glutamic acid derivatives
US9265746B2 (en) * 2006-05-31 2016-02-23 Merck & Cie Method for cell-specific targeting

Also Published As

Publication number Publication date
AT329312B (de) 1976-05-10
NL7309977A (US07223432-20070529-C00017.png) 1974-01-28
GB1442772A (en) 1976-07-14
AU476551B2 (en) 1976-09-30
FR2193608A1 (US07223432-20070529-C00017.png) 1974-02-22
SE431612B (sv) 1984-02-20
JPS4950113A (US07223432-20070529-C00017.png) 1974-05-15
ATA633073A (de) 1975-07-15
DE2335898A1 (de) 1974-02-07
CA1006093A (en) 1977-03-01
US3856959A (en) 1974-12-24
JPS5541207B2 (US07223432-20070529-C00017.png) 1980-10-22
AU5782073A (en) 1975-01-09
FR2193608B1 (US07223432-20070529-C00017.png) 1976-08-13

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: GOUVERNEMENT DES ETATS-UNIS D AMERIQUE REPRESENTE

Effective date: 19840724